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The map label for this gene is malL [H]

Identifier: 116494486

GI number: 116494486

Start: 964491

End: 966167

Strand: Direct

Name: malL [H]

Synonym: LSEI_0980

Alternate gene names: 116494486

Gene position: 964491-966167 (Clockwise)

Preceding gene: 116494485

Following gene: 116494487

Centisome position: 33.31

GC content: 47.94

Gene sequence:

>1677_bases
ATGAGCACTTGGTATGATCGGGCGATTATTTATCAAATTTATCCGAAGTCATTTCAGGACAGTGATGGCGATGGTATTGG
GGATCTTAACGGCATTCGGCAACGCATACCGTATCTGCAGGACTTAGGCATCAACGCCGTTTGGCTGAATCCTGTGTTTG
TATCACCGCAAGTCGATAATGGGTATGATGTCGCCAACTATTACGCGATTGATGAGCGAATGGGAACGATGGCCGATATG
CAGGCTTTGATTCATGAACTTCATGAAGCGGGTATCCGTATCATCTTGGATTTTGTTTTGAACCACACATCGGATCAGCA
CCCGTGGTTTCAAGATGCAAGCCGGAATGTAAAAAGTATTTATCGTGATTATTATATTTTTTCTGGACATCATCATAAAA
GACCAAATAATTGGGGAAGCTTCTTCGGCGGCTCGGTTTGGTCGCCTGATCCAGCCGGTACCGGTCAATCCTATTTCCAT
TTATTTGATCAGCACATGCCGGATTTGAATTGGGCCAATGCCGAGGTTCGGCGTGCAATGGGGGATGTTGCTGAATTTTG
GCTAAACAAGGGAATTGATGGGTTGCGGCTTGACGCGTTTATTCATATTGCCAAAGTTGATCTGGCGCAAAACTATCCAA
CGTCGGAAAGCCAACAAGAGCCTGTGATTGCAGAACCGTTTTTTGCTAATCTGCCCAATGTTCAGCGGTGGTTGCGGCCC
TTCTGTGCTCAGATCAAGGCAGATTTTCCAAATACCTTTATACTTGGGGAAGCAGCAAGTGCAAATGTCAATCTTGCTGT
TGACTACACGAGCCAGCATAACAAATTGATGGATAGTGTGATTACTTTCCGATATTTTACCGAAGATACGACGCAACTTG
ACACCAGCATCCCAGCGCAGTATCAGCCGAAACCTTTGGATTTTGCAAAGTTTAAACAGACACAGGTTGTTTGGCAGCAA
ACACTTGCTGGTGTGTCGTTGCCGACGCTTTATTGGGGCAATCATGATATGGCTCGTCTGGCTACGCGCGTTGCCCATTC
AGCGATTCAGGCGAGAAGTCTGGCAGTGCTGATGTATTTACAACGCGGTATTCCAATCATCTATTACGGTGAAGAGCTAG
GGCTTGAAAATCTCACGTTGCCTGATGCAAAAGCTTTTTCCGATCCAAGCGTCCCGCGCTTCATTGCAGCAGCTGTGGAT
GCAGGGTATACCCAGGAGGCGGCGTTAGCGATGGTCAATGCGACCCATAAGTTGCCAGCGAGAGGGCCGATGACGTGGGA
TGCGACAACCAATAGTGGCTTTACGAGCGGCACGCCTTGGTTGGTTGGCAAGCGCAGCAGTCGCACGCATGTTGTCGAAC
AACAACATGATCCGCACAGCAGCCTTGCATTTTACAAGCAATTGATTGCTTTAAAGAAACGGTCGGTCTTTCAAACAGGC
AGTTTTCGACTGTTGAGTACGGGGCCAGACAGCTATGTGTATCTTCGCCAGACAGACAAGGCGATTGCCGTTGTGGCGGT
TGCTTTGAGTGATAAAACAGTCAACCTTAGATTGCCAGCCGGTGACTATCAAGCGGTGCTAATCGTCGGTGACGCGACAC
TGAGCGAAGAAACACTGACACTATCAGCCGATTCAGCAGCAGTATTCATTCAGGAAAAGGAGCGTGCTAAGCCATGA

Upstream 100 bases:

>100_bases
TGGCTTTTCTTCACTTCATTTTGATAACGGTAACAAACGCAGTTAACTTGTATCATGCGTGCGCTTTCACTATGCTAGTT
GGAAAAGGGGGGCGGGTCAC

Downstream 100 bases:

>100_bases
ATTTAGCAGCTATGTCTCATCGACCAGAAAGTGAAGATTGTTTCTTATATACCAATAAAAAGCTACGTTTGCGGTTCCAT
ACGGCACAAAACGATGTCGC

Product: alpha-glucosidase

Products: NA

Alternate protein names: Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase [H]

Number of amino acids: Translated: 558; Mature: 557

Protein sequence:

>558_residues
MSTWYDRAIIYQIYPKSFQDSDGDGIGDLNGIRQRIPYLQDLGINAVWLNPVFVSPQVDNGYDVANYYAIDERMGTMADM
QALIHELHEAGIRIILDFVLNHTSDQHPWFQDASRNVKSIYRDYYIFSGHHHKRPNNWGSFFGGSVWSPDPAGTGQSYFH
LFDQHMPDLNWANAEVRRAMGDVAEFWLNKGIDGLRLDAFIHIAKVDLAQNYPTSESQQEPVIAEPFFANLPNVQRWLRP
FCAQIKADFPNTFILGEAASANVNLAVDYTSQHNKLMDSVITFRYFTEDTTQLDTSIPAQYQPKPLDFAKFKQTQVVWQQ
TLAGVSLPTLYWGNHDMARLATRVAHSAIQARSLAVLMYLQRGIPIIYYGEELGLENLTLPDAKAFSDPSVPRFIAAAVD
AGYTQEAALAMVNATHKLPARGPMTWDATTNSGFTSGTPWLVGKRSSRTHVVEQQHDPHSSLAFYKQLIALKKRSVFQTG
SFRLLSTGPDSYVYLRQTDKAIAVVAVALSDKTVNLRLPAGDYQAVLIVGDATLSEETLTLSADSAAVFIQEKERAKP

Sequences:

>Translated_558_residues
MSTWYDRAIIYQIYPKSFQDSDGDGIGDLNGIRQRIPYLQDLGINAVWLNPVFVSPQVDNGYDVANYYAIDERMGTMADM
QALIHELHEAGIRIILDFVLNHTSDQHPWFQDASRNVKSIYRDYYIFSGHHHKRPNNWGSFFGGSVWSPDPAGTGQSYFH
LFDQHMPDLNWANAEVRRAMGDVAEFWLNKGIDGLRLDAFIHIAKVDLAQNYPTSESQQEPVIAEPFFANLPNVQRWLRP
FCAQIKADFPNTFILGEAASANVNLAVDYTSQHNKLMDSVITFRYFTEDTTQLDTSIPAQYQPKPLDFAKFKQTQVVWQQ
TLAGVSLPTLYWGNHDMARLATRVAHSAIQARSLAVLMYLQRGIPIIYYGEELGLENLTLPDAKAFSDPSVPRFIAAAVD
AGYTQEAALAMVNATHKLPARGPMTWDATTNSGFTSGTPWLVGKRSSRTHVVEQQHDPHSSLAFYKQLIALKKRSVFQTG
SFRLLSTGPDSYVYLRQTDKAIAVVAVALSDKTVNLRLPAGDYQAVLIVGDATLSEETLTLSADSAAVFIQEKERAKP
>Mature_557_residues
STWYDRAIIYQIYPKSFQDSDGDGIGDLNGIRQRIPYLQDLGINAVWLNPVFVSPQVDNGYDVANYYAIDERMGTMADMQ
ALIHELHEAGIRIILDFVLNHTSDQHPWFQDASRNVKSIYRDYYIFSGHHHKRPNNWGSFFGGSVWSPDPAGTGQSYFHL
FDQHMPDLNWANAEVRRAMGDVAEFWLNKGIDGLRLDAFIHIAKVDLAQNYPTSESQQEPVIAEPFFANLPNVQRWLRPF
CAQIKADFPNTFILGEAASANVNLAVDYTSQHNKLMDSVITFRYFTEDTTQLDTSIPAQYQPKPLDFAKFKQTQVVWQQT
LAGVSLPTLYWGNHDMARLATRVAHSAIQARSLAVLMYLQRGIPIIYYGEELGLENLTLPDAKAFSDPSVPRFIAAAVDA
GYTQEAALAMVNATHKLPARGPMTWDATTNSGFTSGTPWLVGKRSSRTHVVEQQHDPHSSLAFYKQLIALKKRSVFQTGS
FRLLSTGPDSYVYLRQTDKAIAVVAVALSDKTVNLRLPAGDYQAVLIVGDATLSEETLTLSADSAAVFIQEKERAKP

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=572, Percent_Identity=27.4475524475524, Blast_Score=206, Evalue=4e-53,
Organism=Escherichia coli, GI1790687, Length=516, Percent_Identity=35.6589147286822, Blast_Score=292, Evalue=4e-80,
Organism=Escherichia coli, GI1786604, Length=549, Percent_Identity=24.0437158469945, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1789995, Length=92, Percent_Identity=33.695652173913, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25147709, Length=490, Percent_Identity=24.6938775510204, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI32565753, Length=381, Percent_Identity=24.4094488188976, Blast_Score=102, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6322245, Length=565, Percent_Identity=28.3185840707965, Blast_Score=234, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6321726, Length=585, Percent_Identity=28.3760683760684, Blast_Score=231, Evalue=3e-61,
Organism=Saccharomyces cerevisiae, GI6322241, Length=585, Percent_Identity=28.3760683760684, Blast_Score=226, Evalue=7e-60,
Organism=Saccharomyces cerevisiae, GI6322021, Length=585, Percent_Identity=28.3760683760684, Blast_Score=226, Evalue=7e-60,
Organism=Saccharomyces cerevisiae, GI6324416, Length=585, Percent_Identity=28.3760683760684, Blast_Score=224, Evalue=3e-59,
Organism=Saccharomyces cerevisiae, GI6319776, Length=561, Percent_Identity=29.0552584670232, Blast_Score=213, Evalue=6e-56,
Organism=Saccharomyces cerevisiae, GI6321731, Length=561, Percent_Identity=28.8770053475936, Blast_Score=213, Evalue=9e-56,
Organism=Drosophila melanogaster, GI24583749, Length=533, Percent_Identity=31.3320825515947, Blast_Score=239, Evalue=4e-63,
Organism=Drosophila melanogaster, GI24583747, Length=533, Percent_Identity=31.3320825515947, Blast_Score=239, Evalue=4e-63,
Organism=Drosophila melanogaster, GI24583745, Length=503, Percent_Identity=33.9960238568588, Blast_Score=237, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24586599, Length=532, Percent_Identity=29.6992481203008, Blast_Score=231, Evalue=1e-60,
Organism=Drosophila melanogaster, GI45549022, Length=543, Percent_Identity=30.0184162062615, Blast_Score=230, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24586589, Length=509, Percent_Identity=31.237721021611, Blast_Score=229, Evalue=4e-60,
Organism=Drosophila melanogaster, GI24586587, Length=500, Percent_Identity=33.6, Blast_Score=224, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24586593, Length=494, Percent_Identity=30.5668016194332, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI221330053, Length=581, Percent_Identity=29.6041308089501, Blast_Score=213, Evalue=4e-55,
Organism=Drosophila melanogaster, GI24586591, Length=501, Percent_Identity=30.1397205588822, Blast_Score=210, Evalue=3e-54,
Organism=Drosophila melanogaster, GI24586597, Length=203, Percent_Identity=44.3349753694581, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI281360393, Length=439, Percent_Identity=26.879271070615, Blast_Score=138, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 62537; Mature: 62406

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTWYDRAIIYQIYPKSFQDSDGDGIGDLNGIRQRIPYLQDLGINAVWLNPVFVSPQVDN
CCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCHHHHCCCCEEEECCEEECCCCCC
GYDVANYYAIDERMGTMADMQALIHELHEAGIRIILDFVLNHTSDQHPWFQDASRNVKSI
CCCHHHEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
YRDYYIFSGHHHKRPNNWGSFFGGSVWSPDPAGTGQSYFHLFDQHMPDLNWANAEVRRAM
HHHHEEECCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
GDVAEFWLNKGIDGLRLDAFIHIAKVDLAQNYPTSESQQEPVIAEPFFANLPNVQRWLRP
HHHHHHHHHCCCCCEEEEEEEEEEEEHHHCCCCCCCCCCCCCEECCHHCCCCHHHHHHHH
FCAQIKADFPNTFILGEAASANVNLAVDYTSQHNKLMDSVITFRYFTEDTTQLDTSIPAQ
HHHHHHCCCCCEEEEECCCCCCEEEEEEECCHHHHHHHHHHHEEEECCCCHHHCCCCCCC
YQPKPLDFAKFKQTQVVWQQTLAGVSLPTLYWGNHDMARLATRVAHSAIQARSLAVLMYL
CCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
QRGIPIIYYGEELGLENLTLPDAKAFSDPSVPRFIAAAVDAGYTQEAALAMVNATHKLPA
HHCCCEEEECHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCC
RGPMTWDATTNSGFTSGTPWLVGKRSSRTHVVEQQHDPHSSLAFYKQLIALKKRSVFQTG
CCCEEECCCCCCCCCCCCCEEEECCCCCCEEHHCCCCCHHHHHHHHHHHHHHHHHHCCCC
SFRLLSTGPDSYVYLRQTDKAIAVVAVALSDKTVNLRLPAGDYQAVLIVGDATLSEETLT
CEEEEECCCCCEEEEEECCCEEEEEEEEECCCEEEEEECCCCCEEEEEEECCCCCCCEEE
LSADSAAVFIQEKERAKP
EECCCEEEEEECCCCCCC
>Mature Secondary Structure 
STWYDRAIIYQIYPKSFQDSDGDGIGDLNGIRQRIPYLQDLGINAVWLNPVFVSPQVDN
CCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCHHHHCCCCEEEECCEEECCCCCC
GYDVANYYAIDERMGTMADMQALIHELHEAGIRIILDFVLNHTSDQHPWFQDASRNVKSI
CCCHHHEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
YRDYYIFSGHHHKRPNNWGSFFGGSVWSPDPAGTGQSYFHLFDQHMPDLNWANAEVRRAM
HHHHEEECCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
GDVAEFWLNKGIDGLRLDAFIHIAKVDLAQNYPTSESQQEPVIAEPFFANLPNVQRWLRP
HHHHHHHHHCCCCCEEEEEEEEEEEEHHHCCCCCCCCCCCCCEECCHHCCCCHHHHHHHH
FCAQIKADFPNTFILGEAASANVNLAVDYTSQHNKLMDSVITFRYFTEDTTQLDTSIPAQ
HHHHHHCCCCCEEEEECCCCCCEEEEEEECCHHHHHHHHHHHEEEECCCCHHHCCCCCCC
YQPKPLDFAKFKQTQVVWQQTLAGVSLPTLYWGNHDMARLATRVAHSAIQARSLAVLMYL
CCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
QRGIPIIYYGEELGLENLTLPDAKAFSDPSVPRFIAAAVDAGYTQEAALAMVNATHKLPA
HHCCCEEEECHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCC
RGPMTWDATTNSGFTSGTPWLVGKRSSRTHVVEQQHDPHSSLAFYKQLIALKKRSVFQTG
CCCEEECCCCCCCCCCCCCEEEECCCCCCEEHHCCCCCHHHHHHHHHHHHHHHHHHCCCC
SFRLLSTGPDSYVYLRQTDKAIAVVAVALSDKTVNLRLPAGDYQAVLIVGDATLSEETLT
CEEEEECCCCCEEEEEECCCEEEEEEEEECCCEEEEEECCCCCEEEEEEECCCCCCCEEE
LSADSAAVFIQEKERAKP
EECCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]