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The map label for this gene is comFA [H]

Identifier: 116494433

GI number: 116494433

Start: 903616

End: 904878

Strand: Direct

Name: comFA [H]

Synonym: LSEI_0926

Alternate gene names: 116494433

Gene position: 903616-904878 (Clockwise)

Preceding gene: 116494431

Following gene: 116494434

Centisome position: 31.21

GC content: 52.57

Gene sequence:

>1263_bases
ATGAATCTTGCTGGGGCACAATTGACAGAAAATGAACTGATGCGCTTAACCGTTTCTAATATAGCACAGGCCACATCACT
GCCAGCGTTGATTCAAGAACACGGGCGCTGGTGTTGCCAACGTTGCGGTGATCGAAAGCCAGTTCAATTGCCTGATGGGC
GGTTTTATTGTTCAGCTTGCGTGAGTTTAGGCTGCTTAACAAATCGTGATTTGCTTTACCGCTTTGAACAGCCGCACCGG
CCTGTTGGCGACGGCTTATTAACGTGGCACGGGACATTGACGCCTGCCCAGCAAAAAGCGTCAACAGCTTTACAAACGAG
TGTTACAGCAGGGGCTGATCATTTGATTTGGGCAGTGACAGGTGCTGGCAAAACCGAGATGCTTTTTCCGACCATTTCAC
AGATGGTACAACAAGGCAAGCGCGTGGCTATTGTTTCGCCGAGAATTGATGTTATTCGGGAGCTTGCGCCGCGACTTCGA
ACTGCTTTTGCAACCACCCCCATCGCCGTTCGATATGGCGGTCATTTTGATCAAACCGACAGTGATTTGGTGCTGGCCAC
CGTGCATCAATTATTACGATTTCATCGGGCTTTTGATCTGATTGTCGTTGATGAGGTCGATGCGTTTCCGATGGCGGGAA
CACCCATGCTCCATCGGGCTGTTCAAGGTGCCCGGCGTGGACCGGTTGTTTATTTAACGGCAACGCCGGATCGGCCATTG
AAGGCGGCGATGCGTAAAGGGTTGATGGTCAGTCGATTGTTTCGTCGATTTCACGGGCACCCTTTGCCAGTTCCAGCGAT
TCGGTTGATGAATTTTAAAAAATTACCGTCCCAGTTGCCACCTGCCATCGTGAAGTGGGTGCGTGATGTCGTGGCGACAG
GGCGGTCATGTTTGCTGTTTGTTCCTAAGATCAGCTGGGCGCCTCAAATTGCTGCGCTTGTTCAACGTAACGGGCTAAGG
GTAGCTGGCGTTGCTAGCACGGACCGTCTACGGGCAGAGAAAATAACGGCTTTTCGTCAGCGGCAAATTCAGGTTTTAGT
CACGACGACAATTTTGGAACGCGGCGTAACGGTGTCCAAGTGTGCGGTTGGGGTCGTGGCCGCAGCCGATCGGGCATTCA
CGGCCTCGGCGCTAGTACAGATCGCTGGTCGAGCCGGGCGGGCAGCCGATAGTGCCGACGATCCGGTTGTCTTTTTCACG
GATCGCTATACGTTAGCATTGCTAGCGGCCAAACGTCAGATTGTCATGATGAATGGACGGTGA

Upstream 100 bases:

>100_bases
TGATGAAACGCGATTTTTTAATGGTATTTGTGTAGTTGCCGGTTTGTTGGATGGTAAGATATTGCTCTGACATGCGTAAT
CTCCTTATGAGGTGATCATG

Downstream 100 bases:

>100_bases
TGGTGATGCGTTGTTGCGGGTGTGATCGCCATGTTGATCGTAGTCCGACATTGAAGGCGTTGTTAGCTGGCAGCAAGTTG
ATAGCACCCCGATTGTGCAG

Product: superfamily II DNA/RNA helicase

Products: NA

Alternate protein names: ATP-dependent helicase ComFA [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MNLAGAQLTENELMRLTVSNIAQATSLPALIQEHGRWCCQRCGDRKPVQLPDGRFYCSACVSLGCLTNRDLLYRFEQPHR
PVGDGLLTWHGTLTPAQQKASTALQTSVTAGADHLIWAVTGAGKTEMLFPTISQMVQQGKRVAIVSPRIDVIRELAPRLR
TAFATTPIAVRYGGHFDQTDSDLVLATVHQLLRFHRAFDLIVVDEVDAFPMAGTPMLHRAVQGARRGPVVYLTATPDRPL
KAAMRKGLMVSRLFRRFHGHPLPVPAIRLMNFKKLPSQLPPAIVKWVRDVVATGRSCLLFVPKISWAPQIAALVQRNGLR
VAGVASTDRLRAEKITAFRQRQIQVLVTTTILERGVTVSKCAVGVVAAADRAFTASALVQIAGRAGRAADSADDPVVFFT
DRYTLALLAAKRQIVMMNGR

Sequences:

>Translated_420_residues
MNLAGAQLTENELMRLTVSNIAQATSLPALIQEHGRWCCQRCGDRKPVQLPDGRFYCSACVSLGCLTNRDLLYRFEQPHR
PVGDGLLTWHGTLTPAQQKASTALQTSVTAGADHLIWAVTGAGKTEMLFPTISQMVQQGKRVAIVSPRIDVIRELAPRLR
TAFATTPIAVRYGGHFDQTDSDLVLATVHQLLRFHRAFDLIVVDEVDAFPMAGTPMLHRAVQGARRGPVVYLTATPDRPL
KAAMRKGLMVSRLFRRFHGHPLPVPAIRLMNFKKLPSQLPPAIVKWVRDVVATGRSCLLFVPKISWAPQIAALVQRNGLR
VAGVASTDRLRAEKITAFRQRQIQVLVTTTILERGVTVSKCAVGVVAAADRAFTASALVQIAGRAGRAADSADDPVVFFT
DRYTLALLAAKRQIVMMNGR
>Mature_420_residues
MNLAGAQLTENELMRLTVSNIAQATSLPALIQEHGRWCCQRCGDRKPVQLPDGRFYCSACVSLGCLTNRDLLYRFEQPHR
PVGDGLLTWHGTLTPAQQKASTALQTSVTAGADHLIWAVTGAGKTEMLFPTISQMVQQGKRVAIVSPRIDVIRELAPRLR
TAFATTPIAVRYGGHFDQTDSDLVLATVHQLLRFHRAFDLIVVDEVDAFPMAGTPMLHRAVQGARRGPVVYLTATPDRPL
KAAMRKGLMVSRLFRRFHGHPLPVPAIRLMNFKKLPSQLPPAIVKWVRDVVATGRSCLLFVPKISWAPQIAALVQRNGLR
VAGVASTDRLRAEKITAFRQRQIQVLVTTTILERGVTVSKCAVGVVAAADRAFTASALVQIAGRAGRAADSADDPVVFFT
DRYTLALLAAKRQIVMMNGR

Specific function: Involved in transformation (competence for DNA uptake). Required for DNA uptake but not for binding. May provide the driving force for transport of DNA through an aqueous channel [H]

COG id: COG4098

COG function: function code L; Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 46046; Mature: 46046

Theoretical pI: Translated: 11.13; Mature: 11.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLAGAQLTENELMRLTVSNIAQATSLPALIQEHGRWCCQRCGDRKPVQLPDGRFYCSAC
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
VSLGCLTNRDLLYRFEQPHRPVGDGLLTWHGTLTPAQQKASTALQTSVTAGADHLIWAVT
HHHCCCCCCHHHEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEE
GAGKTEMLFPTISQMVQQGKRVAIVSPRIDVIRELAPRLRTAFATTPIAVRYGGHFDQTD
CCCCCEEHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
SDLVLATVHQLLRFHRAFDLIVVDEVDAFPMAGTPMLHRAVQGARRGPVVYLTATPDRPL
CCHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCHH
KAAMRKGLMVSRLFRRFHGHPLPVPAIRLMNFKKLPSQLPPAIVKWVRDVVATGRSCLLF
HHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCHHCCCHHHHHHHHHHHHCCCEEEEE
VPKISWAPQIAALVQRNGLRVAGVASTDRLRAEKITAFRQRQIQVLVTTTILERGVTVSK
ECCCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHEEEEEEHHHHHCCCCHHH
CAVGVVAAADRAFTASALVQIAGRAGRAADSADDPVVFFTDRYTLALLAAKRQIVMMNGR
HHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHHHCCEEEEECCC
>Mature Secondary Structure
MNLAGAQLTENELMRLTVSNIAQATSLPALIQEHGRWCCQRCGDRKPVQLPDGRFYCSAC
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
VSLGCLTNRDLLYRFEQPHRPVGDGLLTWHGTLTPAQQKASTALQTSVTAGADHLIWAVT
HHHCCCCCCHHHEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEE
GAGKTEMLFPTISQMVQQGKRVAIVSPRIDVIRELAPRLRTAFATTPIAVRYGGHFDQTD
CCCCCEEHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
SDLVLATVHQLLRFHRAFDLIVVDEVDAFPMAGTPMLHRAVQGARRGPVVYLTATPDRPL
CCHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCHH
KAAMRKGLMVSRLFRRFHGHPLPVPAIRLMNFKKLPSQLPPAIVKWVRDVVATGRSCLLF
HHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCHHCCCHHHHHHHHHHHHCCCEEEEE
VPKISWAPQIAALVQRNGLRVAGVASTDRLRAEKITAFRQRQIQVLVTTTILERGVTVSK
ECCCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHEEEEEEHHHHHCCCCHHH
CAVGVVAAADRAFTASALVQIAGRAGRAADSADDPVVFFTDRYTLALLAAKRQIVMMNGR
HHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHHHCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8412657; 9384377 [H]