The gene/protein map for NC_011896 is currently unavailable.
Definition Lactobacillus casei ATCC 334, complete genome.
Accession NC_008526
Length 2,895,264

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The map label for this gene is ppiB [C]

Identifier: 116494371

GI number: 116494371

Start: 822265

End: 822849

Strand: Direct

Name: ppiB [C]

Synonym: LSEI_0827

Alternate gene names: 116494371

Gene position: 822265-822849 (Clockwise)

Preceding gene: 116494367

Following gene: 116494372

Centisome position: 28.4

GC content: 45.47

Gene sequence:

>585_bases
ATGGATTACCCACAATTAGAACTCAAAGACTTTAAGGGACCAAAAGCGATTTTTGAAACAAGCGAAGGTCGCTTTGAAAT
CGCACTTTTCCCTGAACAGGCGCCAAAGACAGTTGAAAACTTTGTAGGCCTTGCCAAAAAACATTATTACGACGGTTTGA
TCTTTCACCGGATTATTGATGATTTCATGATTCAAGGCGGCGACCCCACCGGTACCGGCATGGGCGGTGAAAGTCTCTGG
GGGAAGCCCTTTAATGATGAGTTTTCAAATCAGCTATTCAATTTGAAAGGTGCACTTTCAATGGCTAATGCTGGTCCAAA
TACGAATGGCAGCCAATTCTTCATTGTGACTAATGCGCATTTAGACCCGAGCATGCAGGCGCAACTAAGTGAGGCTGGAT
TCCCAGAACCCATCATTGAAGCGTATAAACAAGGCGGTACACCGTGGCTCGATCATCGCCACACAGTCTTTGGCCAAGTC
CTAAGTGGCCTGTCCGTGGTTGAGAAGATTAGTAAAGTCAAAACAGGTGCTAATGATAAGCCGGTTGAACCGGTCACGAT
TGATCAGGTTACGATTGAAGACTAA

Upstream 100 bases:

>100_bases
GACGATCGTTGCATCAGCAAGCCTGTGTAGTTTGCGCTCAGGGGCTGGGCTGGTATACTACGCCTAGTACAAGAACGTTA
ACTTGTAAAGGAGATTGATC

Downstream 100 bases:

>100_bases
TATTGGTCGGCAATGATTTTTAGGGTATACTCAAAGAGAAATCCAATGAAATGAAGTGTCAGAATGGAATATCGCATAGG
AGATATCTTGACTGGCAAAG

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Phosphatase; Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MDYPQLELKDFKGPKAIFETSEGRFEIALFPEQAPKTVENFVGLAKKHYYDGLIFHRIIDDFMIQGGDPTGTGMGGESLW
GKPFNDEFSNQLFNLKGALSMANAGPNTNGSQFFIVTNAHLDPSMQAQLSEAGFPEPIIEAYKQGGTPWLDHRHTVFGQV
LSGLSVVEKISKVKTGANDKPVEPVTIDQVTIED

Sequences:

>Translated_194_residues
MDYPQLELKDFKGPKAIFETSEGRFEIALFPEQAPKTVENFVGLAKKHYYDGLIFHRIIDDFMIQGGDPTGTGMGGESLW
GKPFNDEFSNQLFNLKGALSMANAGPNTNGSQFFIVTNAHLDPSMQAQLSEAGFPEPIIEAYKQGGTPWLDHRHTVFGQV
LSGLSVVEKISKVKTGANDKPVEPVTIDQVTIED
>Mature_194_residues
MDYPQLELKDFKGPKAIFETSEGRFEIALFPEQAPKTVENFVGLAKKHYYDGLIFHRIIDDFMIQGGDPTGTGMGGESLW
GKPFNDEFSNQLFNLKGALSMANAGPNTNGSQFFIVTNAHLDPSMQAQLSEAGFPEPIIEAYKQGGTPWLDHRHTVFGQV
LSGLSVVEKISKVKTGANDKPVEPVTIDQVTIED

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

Organism=Homo sapiens, GI24308049, Length=189, Percent_Identity=47.6190476190476, Blast_Score=158, Evalue=3e-39,
Organism=Homo sapiens, GI7706339, Length=175, Percent_Identity=45.7142857142857, Blast_Score=148, Evalue=4e-36,
Organism=Homo sapiens, GI19557636, Length=178, Percent_Identity=42.1348314606742, Blast_Score=140, Evalue=8e-34,
Organism=Homo sapiens, GI64276486, Length=181, Percent_Identity=37.0165745856354, Blast_Score=125, Evalue=2e-29,
Organism=Homo sapiens, GI22547212, Length=177, Percent_Identity=43.5028248587571, Blast_Score=123, Evalue=1e-28,
Organism=Homo sapiens, GI7657473, Length=177, Percent_Identity=43.5028248587571, Blast_Score=123, Evalue=1e-28,
Organism=Homo sapiens, GI22547215, Length=177, Percent_Identity=43.5028248587571, Blast_Score=123, Evalue=1e-28,
Organism=Homo sapiens, GI4758950, Length=173, Percent_Identity=44.5086705202312, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI5454154, Length=177, Percent_Identity=40.6779661016949, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI4505991, Length=170, Percent_Identity=43.5294117647059, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI10863927, Length=169, Percent_Identity=40.8284023668639, Blast_Score=107, Evalue=9e-24,
Organism=Homo sapiens, GI42560244, Length=184, Percent_Identity=39.6739130434783, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI4826932, Length=204, Percent_Identity=35.7843137254902, Blast_Score=103, Evalue=7e-23,
Organism=Homo sapiens, GI20911035, Length=185, Percent_Identity=32.4324324324324, Blast_Score=103, Evalue=7e-23,
Organism=Homo sapiens, GI256017253, Length=169, Percent_Identity=39.0532544378698, Blast_Score=100, Evalue=8e-22,
Organism=Homo sapiens, GI221139811, Length=169, Percent_Identity=39.0532544378698, Blast_Score=100, Evalue=8e-22,
Organism=Homo sapiens, GI256017251, Length=169, Percent_Identity=39.0532544378698, Blast_Score=100, Evalue=8e-22,
Organism=Homo sapiens, GI178057341, Length=169, Percent_Identity=39.0532544378698, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI6631100, Length=177, Percent_Identity=37.8531073446328, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI5031987, Length=179, Percent_Identity=39.6648044692737, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI45439316, Length=159, Percent_Identity=39.622641509434, Blast_Score=98, Evalue=4e-21,
Organism=Homo sapiens, GI5174637, Length=169, Percent_Identity=38.4615384615385, Blast_Score=98, Evalue=4e-21,
Organism=Homo sapiens, GI209417936, Length=169, Percent_Identity=38.4615384615385, Blast_Score=98, Evalue=5e-21,
Organism=Homo sapiens, GI30102944, Length=169, Percent_Identity=38.4615384615385, Blast_Score=98, Evalue=5e-21,
Organism=Homo sapiens, GI219842199, Length=169, Percent_Identity=38.4615384615385, Blast_Score=98, Evalue=5e-21,
Organism=Homo sapiens, GI303305009, Length=152, Percent_Identity=40.1315789473684, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI310129267, Length=156, Percent_Identity=41.025641025641, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI310120620, Length=156, Percent_Identity=41.025641025641, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI310110104, Length=170, Percent_Identity=38.8235294117647, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI169164185, Length=173, Percent_Identity=38.728323699422, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI169163623, Length=173, Percent_Identity=38.728323699422, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI169163387, Length=173, Percent_Identity=38.728323699422, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI310127646, Length=173, Percent_Identity=38.150289017341, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI310114371, Length=173, Percent_Identity=38.150289017341, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI310119221, Length=173, Percent_Identity=38.150289017341, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI27735045, Length=176, Percent_Identity=32.3863636363636, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI310132444, Length=169, Percent_Identity=36.094674556213, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI310113152, Length=169, Percent_Identity=36.094674556213, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI150418007, Length=152, Percent_Identity=38.1578947368421, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI310114540, Length=161, Percent_Identity=36.6459627329193, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI310127745, Length=145, Percent_Identity=38.6206896551724, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI310119290, Length=145, Percent_Identity=38.6206896551724, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI14277126, Length=195, Percent_Identity=31.2820512820513, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI239751853, Length=174, Percent_Identity=34.4827586206897, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI113428306, Length=174, Percent_Identity=34.4827586206897, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI169214050, Length=174, Percent_Identity=34.4827586206897, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI289803023, Length=202, Percent_Identity=27.7227722772277, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1786736, Length=186, Percent_Identity=34.9462365591398, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1789763, Length=185, Percent_Identity=32.4324324324324, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17539496, Length=177, Percent_Identity=44.0677966101695, Blast_Score=145, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17506311, Length=182, Percent_Identity=41.7582417582418, Blast_Score=132, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI71980594, Length=177, Percent_Identity=39.5480225988701, Blast_Score=129, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI71997782, Length=170, Percent_Identity=40.5882352941176, Blast_Score=127, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71980590, Length=166, Percent_Identity=39.7590361445783, Blast_Score=125, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17532641, Length=175, Percent_Identity=39.4285714285714, Blast_Score=122, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17552780, Length=170, Percent_Identity=44.1176470588235, Blast_Score=121, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17506307, Length=169, Percent_Identity=44.3786982248521, Blast_Score=120, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17565860, Length=192, Percent_Identity=42.7083333333333, Blast_Score=117, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17551282, Length=178, Percent_Identity=39.3258426966292, Blast_Score=112, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17551284, Length=178, Percent_Identity=39.3258426966292, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17532643, Length=181, Percent_Identity=39.2265193370166, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17566266, Length=173, Percent_Identity=39.3063583815029, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17539498, Length=157, Percent_Identity=40.1273885350318, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17559074, Length=178, Percent_Identity=38.7640449438202, Blast_Score=104, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17552784, Length=185, Percent_Identity=38.9189189189189, Blast_Score=103, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17552782, Length=176, Percent_Identity=38.0681818181818, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI32563659, Length=187, Percent_Identity=32.620320855615, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6321848, Length=177, Percent_Identity=41.2429378531073, Blast_Score=119, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6323562, Length=179, Percent_Identity=41.340782122905, Blast_Score=114, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6320510, Length=170, Percent_Identity=41.7647058823529, Blast_Score=112, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6320359, Length=155, Percent_Identity=41.9354838709677, Blast_Score=106, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6323246, Length=198, Percent_Identity=36.8686868686869, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6322492, Length=205, Percent_Identity=31.7073170731707, Blast_Score=74, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17986117, Length=177, Percent_Identity=44.6327683615819, Blast_Score=150, Evalue=3e-37,
Organism=Drosophila melanogaster, GI19922376, Length=174, Percent_Identity=37.3563218390805, Blast_Score=134, Evalue=3e-32,
Organism=Drosophila melanogaster, GI20130249, Length=195, Percent_Identity=46.6666666666667, Blast_Score=130, Evalue=8e-31,
Organism=Drosophila melanogaster, GI19922912, Length=181, Percent_Identity=43.0939226519337, Blast_Score=118, Evalue=3e-27,
Organism=Drosophila melanogaster, GI17647301, Length=177, Percent_Identity=38.9830508474576, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24586038, Length=200, Percent_Identity=38, Blast_Score=111, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24652460, Length=178, Percent_Identity=35.3932584269663, Blast_Score=110, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24650807, Length=191, Percent_Identity=36.6492146596859, Blast_Score=106, Evalue=8e-24,
Organism=Drosophila melanogaster, GI45549139, Length=166, Percent_Identity=40.9638554216867, Blast_Score=106, Evalue=8e-24,
Organism=Drosophila melanogaster, GI17136360, Length=175, Percent_Identity=38.2857142857143, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24664125, Length=190, Percent_Identity=37.8947368421053, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21357783, Length=190, Percent_Identity=37.8947368421053, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21357249, Length=103, Percent_Identity=44.6601941747573, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21355677, Length=187, Percent_Identity=28.8770053475936, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24661775, Length=184, Percent_Identity=32.0652173913043, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21355237, Length=184, Percent_Identity=32.0652173913043, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24661771, Length=184, Percent_Identity=32.0652173913043, Blast_Score=74, Evalue=6e-14,

Paralogues:

None

Copy number: 780 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150
- InterPro:   IPR002130 [H]

Pfam domain/function: PF08282 Hydrolase_3; PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 21349; Mature: 21349

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MDYPQLELKDFKGPKAIFETSEGRFEIALFPEQAPKTVENFVGLAKKHYYDGLIFHRIID
CCCCCCCHHCCCCCHHHEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DFMIQGGDPTGTGMGGESLWGKPFNDEFSNQLFNLKGALSMANAGPNTNGSQFFIVTNAH
HHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEEECC
LDPSMQAQLSEAGFPEPIIEAYKQGGTPWLDHRHTVFGQVLSGLSVVEKISKVKTGANDK
CCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PVEPVTIDQVTIED
CCCCEEECEEEECC
>Mature Secondary Structure
MDYPQLELKDFKGPKAIFETSEGRFEIALFPEQAPKTVENFVGLAKKHYYDGLIFHRIID
CCCCCCCHHCCCCCHHHEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DFMIQGGDPTGTGMGGESLWGKPFNDEFSNQLFNLKGALSMANAGPNTNGSQFFIVTNAH
HHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEEECC
LDPSMQAQLSEAGFPEPIIEAYKQGGTPWLDHRHTVFGQVLSGLSVVEKISKVKTGANDK
CCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PVEPVTIDQVTIED
CCCCEEECEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA