Click here to switch to the map view.

The map label for this gene is yunD [H]

Identifier: 116494363

GI number: 116494363

Start: 816202

End: 817578

Strand: Direct

Name: yunD [H]

Synonym: LSEI_0819

Alternate gene names: 116494363

Gene position: 816202-817578 (Clockwise)

Preceding gene: 116494362

Following gene: 116494364

Centisome position: 28.19

GC content: 46.84

Gene sequence:

>1377_bases
GTGGAAAAGTTAGTGATCCTGCATACCAATGATCTGCATTCTCATTTTGAAAATTGGCCGAAGATTCGGCGGTTTATGTT
GGGAACACGCGCTGCAGAACAAGCAGAAGGCGCGAGTGTGTTGGCATTTGATGACGGGGATGCGATGGATCGCTCAGCGC
CCTTAACGGAGGCTACGCAAGGTCAGATCAATGTGCAATTGCTGAATGAAATTGGTTACGATGCAGCAACCATCGGCAAT
AATGAAGGTGTCGGTAACCCGCATGATGTGCTGGAACATTTATACGATCATGCGAACTTTCCAGTGGCACTGGCTAATTT
ATTCGAGGTTGACGGCAGCCGACCGACATGGGCTAAACCGTTTGTGCGAACGCAAACGCGTGCTGGTACACGCATTGCGA
TTGTCGGATTCACGGCGCCATTTTTTCTGACATATCGACCAAATGGCTGGCAAGTTAAAACCGTGGCGGATGTATTTCCG
GATATTTTGAAGCAATTATCAGGTACCTATGACGTGTTAATTGTGCTGTCACATTTAGGAATTGAGGCTGATCGGCACTT
AGCAAAACAGTATCCAGAGATTGATGTCGTGATTGGTGGTCATACGCATCATTTATTGGCAGACGGCGAGTTACATGGCA
CCACCTTATTAACAGCTGCAGAAAAGTATGGCCATTATGTCGGCAAAGTGACGCTGACGCTGGATGATCAGCATCAAATT
ATCACCCGTCAGGCCGAGACATTTAAAACTGAGCTCATGCAAGCGGCAGCTGCTGACCCGCGTGAGATACAGGGCTATGA
GAGCAAAGGAATTGCTTTGCTCAAGCAGCATCAGGTGGCGCGGTTGCCCAAGCAGCTATCGATCAAATATGATGGGCCTT
CACCATTACTGGATTTAGGTTTAGAAGCATTGGCTGATGGCGCTCAGGTGGACGCGGCGATTTTAAATGCCGGACTTTTC
CTTATGCCGCTGGGTCCGGGTGTTGTCACCCAAGCGGATTTATTAACCTGTTTGCCGCATCCCATGCATCTGTTAAAAGT
AACGCTGAGTGGTAAGGAACTGTGGCGCTTAATCATGGAAATGGAAAAGAATCGAATGTTCCTGCGACATTTTCATATGA
TCGGCATGAGTTTTCGTGGCAAGATTTTTGGTGACATTGGTTACCGGGGGATTAGCGTTAATCGTGAAAAACGGGTTGTT
CTATGGCATGGGAAACCGTTGGTGCCAGAACAACAATATACGTTTGTGACGGTGGACAATTTTCTGTTCATTCCATTCTT
TCCAACCATTGAGATTATGGGCAGCAATGAATTGCTTTTTCCTAAGCTATTACGGAATGTGGTGGGCGAGTACTTAGCTC
AAAAATATCCATTATGA

Upstream 100 bases:

>100_bases
TTTGACCGCCCGCTTATCAGAGCATAGGATAAAAATAAGAAAGCGCGCCGGTGATTCACCAGTTAGAGTATTTATTTTTG
CCGGCACAGGGAGGTTTCTC

Downstream 100 bases:

>100_bases
TTTCGTGATATACTTTGCGAAGCATCAGCACACATAAGGAGGTGAGCACATGGGCGAACATGAACCGCTTATACAACAAA
TTGATGCCGCATTGACCCCA

Product: 5'-nucleotidase/2',3'-cyclic phosphodiesterase related esterase

Products: Phosphate; Uridine [C]

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MEKLVILHTNDLHSHFENWPKIRRFMLGTRAAEQAEGASVLAFDDGDAMDRSAPLTEATQGQINVQLLNEIGYDAATIGN
NEGVGNPHDVLEHLYDHANFPVALANLFEVDGSRPTWAKPFVRTQTRAGTRIAIVGFTAPFFLTYRPNGWQVKTVADVFP
DILKQLSGTYDVLIVLSHLGIEADRHLAKQYPEIDVVIGGHTHHLLADGELHGTTLLTAAEKYGHYVGKVTLTLDDQHQI
ITRQAETFKTELMQAAAADPREIQGYESKGIALLKQHQVARLPKQLSIKYDGPSPLLDLGLEALADGAQVDAAILNAGLF
LMPLGPGVVTQADLLTCLPHPMHLLKVTLSGKELWRLIMEMEKNRMFLRHFHMIGMSFRGKIFGDIGYRGISVNREKRVV
LWHGKPLVPEQQYTFVTVDNFLFIPFFPTIEIMGSNELLFPKLLRNVVGEYLAQKYPL

Sequences:

>Translated_458_residues
MEKLVILHTNDLHSHFENWPKIRRFMLGTRAAEQAEGASVLAFDDGDAMDRSAPLTEATQGQINVQLLNEIGYDAATIGN
NEGVGNPHDVLEHLYDHANFPVALANLFEVDGSRPTWAKPFVRTQTRAGTRIAIVGFTAPFFLTYRPNGWQVKTVADVFP
DILKQLSGTYDVLIVLSHLGIEADRHLAKQYPEIDVVIGGHTHHLLADGELHGTTLLTAAEKYGHYVGKVTLTLDDQHQI
ITRQAETFKTELMQAAAADPREIQGYESKGIALLKQHQVARLPKQLSIKYDGPSPLLDLGLEALADGAQVDAAILNAGLF
LMPLGPGVVTQADLLTCLPHPMHLLKVTLSGKELWRLIMEMEKNRMFLRHFHMIGMSFRGKIFGDIGYRGISVNREKRVV
LWHGKPLVPEQQYTFVTVDNFLFIPFFPTIEIMGSNELLFPKLLRNVVGEYLAQKYPL
>Mature_458_residues
MEKLVILHTNDLHSHFENWPKIRRFMLGTRAAEQAEGASVLAFDDGDAMDRSAPLTEATQGQINVQLLNEIGYDAATIGN
NEGVGNPHDVLEHLYDHANFPVALANLFEVDGSRPTWAKPFVRTQTRAGTRIAIVGFTAPFFLTYRPNGWQVKTVADVFP
DILKQLSGTYDVLIVLSHLGIEADRHLAKQYPEIDVVIGGHTHHLLADGELHGTTLLTAAEKYGHYVGKVTLTLDDQHQI
ITRQAETFKTELMQAAAADPREIQGYESKGIALLKQHQVARLPKQLSIKYDGPSPLLDLGLEALADGAQVDAAILNAGLF
LMPLGPGVVTQADLLTCLPHPMHLLKVTLSGKELWRLIMEMEKNRMFLRHFHMIGMSFRGKIFGDIGYRGISVNREKRVV
LWHGKPLVPEQQYTFVTVDNFLFIPFFPTIEIMGSNELLFPKLLRNVVGEYLAQKYPL

Specific function: Degradation Of External Udp-Glucose To Uridine Monophosphate And Glucose-1-Phosphate, Which Can Then Be Used By The Cell. [C]

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallophosphoesterase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786687, Length=232, Percent_Identity=26.7241379310345, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573524, Length=439, Percent_Identity=21.4123006833713, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19922444, Length=288, Percent_Identity=23.6111111111111, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19922446, Length=232, Percent_Identity=25.4310344827586, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24654424, Length=232, Percent_Identity=25.4310344827586, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006179
- InterPro:   IPR011240 [H]

Pfam domain/function: PF02872 5_nucleotid_C [H]

EC number: 3.6.1.45; 3.1.3.5 [C]

Molecular weight: Translated: 51136; Mature: 51136

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00785 5_NUCLEOTIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLVILHTNDLHSHFENWPKIRRFMLGTRAAEQAEGASVLAFDDGDAMDRSAPLTEATQ
CCCEEEEECCHHHHHHHHHHHHHHHHHHCHHHHHCCCCEEEEECCCCCCCCCCCCCCCCC
GQINVQLLNEIGYDAATIGNNEGVGNPHDVLEHLYDHANFPVALANLFEVDGSRPTWAKP
CEEEEEEHHHCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCEEEHHHHHCCCCCCCCCCC
FVRTQTRAGTRIAIVGFTAPFFLTYRPNGWQVKTVADVFPDILKQLSGTYDVLIVLSHLG
HHHHHCCCCCEEEEEEECCCEEEEECCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHC
IEADRHLAKQYPEIDVVIGGHTHHLLADGELHGTTLLTAAEKYGHYVGKVTLTLDDQHQI
CCHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCCHHHHHHHHCCEEEEEEEEECCCHHH
ITRQAETFKTELMQAAAADPREIQGYESKGIALLKQHQVARLPKQLSIKYDGPSPLLDLG
HHHHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHCCHHEEEEECCCCHHHHHH
LEALADGAQVDAAILNAGLFLMPLGPGVVTQADLLTCLPHPMHLLKVTLSGKELWRLIME
HHHHCCCCHHHHHHHCCCEEEEECCCCCCCHHHHHHHCCCCCEEEEEEECHHHHHHHHHH
MEKNRMFLRHFHMIGMSFRGKIFGDIGYRGISVNREKRVVLWHGKPLVPEQQYTFVTVDN
HHHCHHHHHHHHHHCCCCCCEEEECCCCEEEEECCCCEEEEECCCCCCCCCCEEEEEECC
FLFIPFFPTIEIMGSNELLFPKLLRNVVGEYLAQKYPL
EEEEECCCEEEEECCCCEEHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEKLVILHTNDLHSHFENWPKIRRFMLGTRAAEQAEGASVLAFDDGDAMDRSAPLTEATQ
CCCEEEEECCHHHHHHHHHHHHHHHHHHCHHHHHCCCCEEEEECCCCCCCCCCCCCCCCC
GQINVQLLNEIGYDAATIGNNEGVGNPHDVLEHLYDHANFPVALANLFEVDGSRPTWAKP
CEEEEEEHHHCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCEEEHHHHHCCCCCCCCCCC
FVRTQTRAGTRIAIVGFTAPFFLTYRPNGWQVKTVADVFPDILKQLSGTYDVLIVLSHLG
HHHHHCCCCCEEEEEEECCCEEEEECCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHC
IEADRHLAKQYPEIDVVIGGHTHHLLADGELHGTTLLTAAEKYGHYVGKVTLTLDDQHQI
CCHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCCHHHHHHHHCCEEEEEEEEECCCHHH
ITRQAETFKTELMQAAAADPREIQGYESKGIALLKQHQVARLPKQLSIKYDGPSPLLDLG
HHHHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHCCHHEEEEECCCCHHHHHH
LEALADGAQVDAAILNAGLFLMPLGPGVVTQADLLTCLPHPMHLLKVTLSGKELWRLIME
HHHHCCCCHHHHHHHCCCEEEEECCCCCCCHHHHHHHCCCCCEEEEEEECHHHHHHHHHH
MEKNRMFLRHFHMIGMSFRGKIFGDIGYRGISVNREKRVVLWHGKPLVPEQQYTFVTVDN
HHHCHHHHHHHHHHCCCCCCEEEECCCCEEEEECCCCEEEEECCCCCCCCCCEEEEEECC
FLFIPFFPTIEIMGSNELLFPKLLRNVVGEYLAQKYPL
EEEEECCCEEEEECCCCEEHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; UMP [C]

Specific reaction: H2O + UMP --> Phosphate + Uridine [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Inhibitor from Salmonella typhimurium cytoplasm [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]