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The map label for this gene is deoD

Identifier: 116493848

GI number: 116493848

Start: 280255

End: 280971

Strand: Direct

Name: deoD

Synonym: LSEI_0280

Alternate gene names: 116493848

Gene position: 280255-280971 (Clockwise)

Preceding gene: 116493847

Following gene: 116493849

Centisome position: 9.68

GC content: 49.23

Gene sequence:

>717_bases
ATGAGCACACATATTGATGCCCCAAAAGGAGCCATTGCCGACGTCGTCTTATTGCCAGGTGATCCATTGCGAGCACAGTA
CATCGCGGAAAACTTTCTGGACAATGCCCAACGTTACAACACGGTGCGGAATGCATTTGGATTCACCGGCACGTTTGAAG
GCCGGCGCGTGTCGGTTCAAGCGACCGGGATGGGCATTCCTTCGATCTCAATTTATGTTAATGAATTGATTCAAGACTAT
GGGGTTAAAACGCTCATTCGCGTTGGCACAGCTGGCGGCATGGGCGAAAATGTCAAAGTTCGCGATGTTGTGCTGGCCCA
AGGATCTTCGACTGATAGCAGCATTATCTTGAATACGTTTGGCGCGGGGCTTTATTTTGCCCCACTAGCCGACTTCAACC
TTCTTCGTGAGGCGGCAAACTTGGCAGATACTAGCGCAATTCGCTATCATGTTGGTAACGTGCTTGGCGAGGATCGCTTT
TATAACGATGAGATGGATCGTCAAAAACTCATTGATTATGAAGTGCTGGCGACTGAGATGGAAACGCCGGCACTTTATCT
ACTTGCGGCTAAGTACCATGTGCACGCGTTATCGATCCTCACGGTTTCAAATCACTTGGTTACAGGTGAAGAAACCTCAG
CCCAAGAGCGACAGACCAGCTTTAATGACATGATCGGTCTGGCACTCGGTGTTGCCAAAACAGTTCCTGATCGTTAG

Upstream 100 bases:

>100_bases
GCCACGATTTTAGATAATTTTGGTGTCACAGGTAATCAAGTTGGCCAGTCGTTCTTAAAGCTGCTTAAATAAACCCACAT
TTTGAAGGAGAATCATTGTC

Downstream 100 bases:

>100_bases
ATAACGCATGAAATCTAGTTATACCAAGGCTTTGGCGCCGTGAATTTTACAGTTGAAATATTTTTTTAATGTGCGTACCA
GTAGGAAACGTGTTATTCTG

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MSTHIDAPKGAIADVVLLPGDPLRAQYIAENFLDNAQRYNTVRNAFGFTGTFEGRRVSVQATGMGIPSISIYVNELIQDY
GVKTLIRVGTAGGMGENVKVRDVVLAQGSSTDSSIILNTFGAGLYFAPLADFNLLREAANLADTSAIRYHVGNVLGEDRF
YNDEMDRQKLIDYEVLATEMETPALYLLAAKYHVHALSILTVSNHLVTGEETSAQERQTSFNDMIGLALGVAKTVPDR

Sequences:

>Translated_238_residues
MSTHIDAPKGAIADVVLLPGDPLRAQYIAENFLDNAQRYNTVRNAFGFTGTFEGRRVSVQATGMGIPSISIYVNELIQDY
GVKTLIRVGTAGGMGENVKVRDVVLAQGSSTDSSIILNTFGAGLYFAPLADFNLLREAANLADTSAIRYHVGNVLGEDRF
YNDEMDRQKLIDYEVLATEMETPALYLLAAKYHVHALSILTVSNHLVTGEETSAQERQTSFNDMIGLALGVAKTVPDR
>Mature_237_residues
STHIDAPKGAIADVVLLPGDPLRAQYIAENFLDNAQRYNTVRNAFGFTGTFEGRRVSVQATGMGIPSISIYVNELIQDYG
VKTLIRVGTAGGMGENVKVRDVVLAQGSSTDSSIILNTFGAGLYFAPLADFNLLREAANLADTSAIRYHVGNVLGEDRFY
NDEMDRQKLIDYEVLATEMETPALYLLAAKYHVHALSILTVSNHLVTGEETSAQERQTSFNDMIGLALGVAKTVPDR

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family

Homologues:

Organism=Escherichia coli, GI1790844, Length=229, Percent_Identity=48.9082969432314, Blast_Score=220, Evalue=6e-59,
Organism=Escherichia coli, GI1790265, Length=154, Percent_Identity=34.4155844155844, Blast_Score=78, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOD_LACC3 (Q03CD2)

Other databases:

- EMBL:   CP000423
- RefSeq:   YP_805582.1
- ProteinModelPortal:   Q03CD2
- SMR:   Q03CD2
- STRING:   Q03CD2
- GeneID:   4421565
- GenomeReviews:   CP000423_GR
- KEGG:   lca:LSEI_0280
- eggNOG:   COG0813
- HOGENOM:   HBG617197
- OMA:   SFETHAF
- PhylomeDB:   Q03CD2
- ProtClustDB:   PRK05819
- BioCyc:   LCAS321967:LSEI_0280-MONOMER
- HAMAP:   MF_01627
- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR000845
- PANTHER:   PTHR21234
- TIGRFAMs:   TIGR00107

Pfam domain/function: PF01048 PNP_UDP_1

EC number: =2.4.2.1

Molecular weight: Translated: 25892; Mature: 25760

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTHIDAPKGAIADVVLLPGDPLRAQYIAENFLDNAQRYNTVRNAFGFTGTFEGRRVSVQ
CCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEE
ATGMGIPSISIYVNELIQDYGVKTLIRVGTAGGMGENVKVRDVVLAQGSSTDSSIILNTF
ECCCCCCHHHHHHHHHHHHHCHHEEEEECCCCCCCCCCEEEEEEEECCCCCCCEEEEEEC
GAGLYFAPLADFNLLREAANLADTSAIRYHVGNVLGEDRFYNDEMDRQKLIDYEVLATEM
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHC
ETPALYLLAAKYHVHALSILTVSNHLVTGEETSAQERQTSFNDMIGLALGVAKTVPDR
CCCEEEEEEEHHHHEEEEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
STHIDAPKGAIADVVLLPGDPLRAQYIAENFLDNAQRYNTVRNAFGFTGTFEGRRVSVQ
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEE
ATGMGIPSISIYVNELIQDYGVKTLIRVGTAGGMGENVKVRDVVLAQGSSTDSSIILNTF
ECCCCCCHHHHHHHHHHHHHCHHEEEEECCCCCCCCCCEEEEEEEECCCCCCCEEEEEEC
GAGLYFAPLADFNLLREAANLADTSAIRYHVGNVLGEDRFYNDEMDRQKLIDYEVLATEM
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHC
ETPALYLLAAKYHVHALSILTVSNHLVTGEETSAQERQTSFNDMIGLALGVAKTVPDR
CCCEEEEEEEHHHHEEEEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA