BacMap

Definition	Lactobacillus casei ATCC 334, complete genome.
Accession	NC_008526
Length	2,895,264

Click here to switch to the map view.

The map label for this gene is znuC [H]

Identifier: 116493813

GI number: 116493813

Start: 241879

End: 242598

Strand: Direct

Name: znuC [H]

Synonym: LSEI_0242

Alternate gene names: 116493813

Gene position: 241879-242598 (Clockwise)

Preceding gene: 116493812

Following gene: 116493814

Centisome position: 8.35

GC content: 46.81

Gene sequence:

>720_bases
ATGAGCGAACCGATTTTGACCGTAAATCATCTCAGTTTTGGTTTTCGGGATCAACAGCTTTATCAGGATCTGAGTTTTCA
GTTGAATGTGGGCTCAATGACAAGTCTTGTCGGTCCAAACGGGGTCGGCAAAACAACCTTAATTCGGTTACTAATGGCGC
AACTAAAACCGCAAGCCGGAACGATTCGCTTTCGGCAACAGCCACCGGTTCGATTGGGTTATGTGCCCCAGTTCCGGAAT
GTTGATACGGAATTTCCGTTGTCGATCCGCAGTTTCATTCAACTCCGGCAGTTGGATCATCTCTTTTTCTGGCATACGGG
TAAGGAGAAGGCTGCCTTGGATGCCGTGATTAAAGCGACTCACCTTGGTAAAATTGCTGATACGCGGCTTGGAATGGCGA
GTGGCGGCGAAAAACAAAAGGCTTATCTGGCACAAGCTCTTTTAGATGATCCTAACTTTCTGATTCTGGATGAATCAACG
GCCAGCTTAGATGTCAACACGAAGCAGGAGTTGATGGATCTGGTGCAGGAGTTGAATCAAACGCGGCAATTAACGGTGCT
ATTTGTGACGCATGATCTGAGCTTAGCCAAAAAGTACACCCAACAATACTTACTACTGACCGGGTCAAGTTATGAGATGA
AGCCAACAGCGCAAATGGATTTGAAAGCAATGCCAGAAGAATTACGCAATGATGCCGAGAATCGTGGGGTGATCGCATGA

Upstream 100 bases:

>100_bases
CCGTTTAAGGCAGAAGAATCCAAATAAAACTGGCCTTTTCATGAAAAGTTCGATACAATAGTAAACCGTAATCGTTACCG
TTTACTATTGGGAGGCAGCT

Downstream 100 bases:

>100_bases
ATTTATTTGCTTATGCATTCATGCAAAATGCATTCATGGCAAGTACGTTTATTGCCATTACCACAGGCATTGTCGGTGTG
TTCGTCGTTGCGCGGAACAT

Product: ABC-type Mn/Zn transport system, ATPase component

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MSEPILTVNHLSFGFRDQQLYQDLSFQLNVGSMTSLVGPNGVGKTTLIRLLMAQLKPQAGTIRFRQQPPVRLGYVPQFRN
VDTEFPLSIRSFIQLRQLDHLFFWHTGKEKAALDAVIKATHLGKIADTRLGMASGGEKQKAYLAQALLDDPNFLILDEST
ASLDVNTKQELMDLVQELNQTRQLTVLFVTHDLSLAKKYTQQYLLLTGSSYEMKPTAQMDLKAMPEELRNDAENRGVIA

Sequences:

>Translated_239_residues
MSEPILTVNHLSFGFRDQQLYQDLSFQLNVGSMTSLVGPNGVGKTTLIRLLMAQLKPQAGTIRFRQQPPVRLGYVPQFRN
VDTEFPLSIRSFIQLRQLDHLFFWHTGKEKAALDAVIKATHLGKIADTRLGMASGGEKQKAYLAQALLDDPNFLILDEST
ASLDVNTKQELMDLVQELNQTRQLTVLFVTHDLSLAKKYTQQYLLLTGSSYEMKPTAQMDLKAMPEELRNDAENRGVIA
>Mature_238_residues
SEPILTVNHLSFGFRDQQLYQDLSFQLNVGSMTSLVGPNGVGKTTLIRLLMAQLKPQAGTIRFRQQPPVRLGYVPQFRNV
DTEFPLSIRSFIQLRQLDHLFFWHTGKEKAALDAVIKATHLGKIADTRLGMASGGEKQKAYLAQALLDDPNFLILDESTA
SLDVNTKQELMDLVQELNQTRQLTVLFVTHDLSLAKKYTQQYLLLTGSSYEMKPTAQMDLKAMPEELRNDAENRGVIA

Specific function: Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system [H]

COG id: COG1121

COG function: function code P; ABC-type Mn/Zn transport systems, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI42490749, Length=198, Percent_Identity=28.2828282828283, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI73747915, Length=204, Percent_Identity=30.8823529411765, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI27881501, Length=187, Percent_Identity=26.7379679144385, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI30795238, Length=207, Percent_Identity=24.1545893719807, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI27881506, Length=230, Percent_Identity=27.3913043478261, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI10947137, Length=230, Percent_Identity=27.3913043478261, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI27436953, Length=182, Percent_Identity=26.9230769230769, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1788165, Length=203, Percent_Identity=33.9901477832512, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1790739, Length=212, Percent_Identity=30.188679245283, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1786345, Length=223, Percent_Identity=28.6995515695067, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1786803, Length=207, Percent_Identity=27.0531400966184, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI87081834, Length=230, Percent_Identity=29.1304347826087, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1789891, Length=201, Percent_Identity=30.8457711442786, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788761, Length=218, Percent_Identity=27.5229357798165, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787041, Length=211, Percent_Identity=27.9620853080569, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI87081782, Length=231, Percent_Identity=30.3030303030303, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1788506, Length=230, Percent_Identity=29.5652173913043, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1789864, Length=257, Percent_Identity=28.0155642023346, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787112, Length=226, Percent_Identity=29.2035398230088, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI2367384, Length=192, Percent_Identity=30.2083333333333, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789873, Length=206, Percent_Identity=28.1553398058252, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1787164, Length=201, Percent_Identity=30.8457711442786, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786698, Length=207, Percent_Identity=26.5700483091787, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790544, Length=228, Percent_Identity=25.4385964912281, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787712, Length=184, Percent_Identity=27.1739130434783, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787758, Length=228, Percent_Identity=24.5614035087719, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI48994943, Length=213, Percent_Identity=25.3521126760563, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1786563, Length=216, Percent_Identity=27.3148148148148, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786398, Length=201, Percent_Identity=27.363184079602, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1786703, Length=229, Percent_Identity=28.82096069869, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789751, Length=213, Percent_Identity=28.6384976525822, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787370, Length=220, Percent_Identity=24.0909090909091, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787547, Length=255, Percent_Identity=25.8823529411765, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787182, Length=217, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786319, Length=189, Percent_Identity=26.4550264550265, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87081791, Length=196, Percent_Identity=26.0204081632653, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1789593, Length=227, Percent_Identity=23.7885462555066, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788450, Length=214, Percent_Identity=24.7663551401869, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082268, Length=214, Percent_Identity=25.2336448598131, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786975, Length=205, Percent_Identity=25.3658536585366, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1789032, Length=242, Percent_Identity=24.3801652892562, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI48994883, Length=227, Percent_Identity=25.5506607929515, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786253, Length=196, Percent_Identity=26.0204081632653, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082267, Length=201, Percent_Identity=24.3781094527363, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789991, Length=212, Percent_Identity=26.8867924528302, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1787105, Length=200, Percent_Identity=27, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=196, Percent_Identity=28.0612244897959, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17543740, Length=208, Percent_Identity=31.7307692307692, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71992285, Length=214, Percent_Identity=29.9065420560748, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115533608, Length=201, Percent_Identity=27.363184079602, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71996550, Length=211, Percent_Identity=26.5402843601896, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17565938, Length=216, Percent_Identity=28.2407407407407, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17555318, Length=207, Percent_Identity=24.6376811594203, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71984940, Length=218, Percent_Identity=28.4403669724771, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI193202349, Length=218, Percent_Identity=26.1467889908257, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17533971, Length=227, Percent_Identity=24.6696035242291, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17510237, Length=195, Percent_Identity=24.1025641025641, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17569143, Length=227, Percent_Identity=28.6343612334802, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17558664, Length=221, Percent_Identity=27.6018099547511, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320874, Length=209, Percent_Identity=29.1866028708134, Blast_Score=88, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6321121, Length=202, Percent_Identity=29.2079207920792, Blast_Score=82, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6324985, Length=210, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323959, Length=256, Percent_Identity=26.171875, Blast_Score=74, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641342, Length=196, Percent_Identity=30.6122448979592, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281363262, Length=202, Percent_Identity=28.7128712871287, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24653245, Length=202, Percent_Identity=28.7128712871287, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI85726357, Length=238, Percent_Identity=25.2100840336134, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24642252, Length=208, Percent_Identity=25.9615384615385, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI18859989, Length=208, Percent_Identity=25.9615384615385, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007184, Length=196, Percent_Identity=27.5510204081633, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221500365, Length=196, Percent_Identity=27.5510204081633, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017882
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 26909; Mature: 26778

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPILTVNHLSFGFRDQQLYQDLSFQLNVGSMTSLVGPNGVGKTTLIRLLMAQLKPQAG
CCCCEEEEECCCCCCCHHHHHHCCCEEECCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCC
TIRFRQQPPVRLGYVPQFRNVDTEFPLSIRSFIQLRQLDHLFFWHTGKEKAALDAVIKAT
EEEECCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHH
HLGKIADTRLGMASGGEKQKAYLAQALLDDPNFLILDESTASLDVNTKQELMDLVQELNQ
HCCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCEEECCCHHHHHHHHHHHCC
TRQLTVLFVTHDLSLAKKYTQQYLLLTGSSYEMKPTAQMDLKAMPEELRNDAENRGVIA
CCEEEEEEEECCHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHCCHHHHCCCCCCCCCC
>Mature Secondary Structure 
SEPILTVNHLSFGFRDQQLYQDLSFQLNVGSMTSLVGPNGVGKTTLIRLLMAQLKPQAG
CCCEEEEECCCCCCCHHHHHHCCCEEECCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCC
TIRFRQQPPVRLGYVPQFRNVDTEFPLSIRSFIQLRQLDHLFFWHTGKEKAALDAVIKAT
EEEECCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHH
HLGKIADTRLGMASGGEKQKAYLAQALLDDPNFLILDESTASLDVNTKQELMDLVQELNQ
HCCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCEEECCCHHHHHHHHHHHCC
TRQLTVLFVTHDLSLAKKYTQQYLLLTGSSYEMKPTAQMDLKAMPEELRNDAENRGVIA
CCEEEEEEEECCHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA