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The map label for this gene is nth [C]

Identifier: 116493740

GI number: 116493740

Start: 167208

End: 167936

Strand: Direct

Name: nth [C]

Synonym: LSEI_0168

Alternate gene names: 116493740

Gene position: 167208-167936 (Clockwise)

Preceding gene: 116493738

Following gene: 116493741

Centisome position: 5.78

GC content: 49.25

Gene sequence:

>729_bases
ATGGATAAACGCTTAATCGTCATGCATAATCTGAGCCGTCATTATGGCAAACAATACTGGTGGCAGCAGAATTCATTGGA
AGATTGGCTGATGATGATTCTCATTCAGCGCACCAGTTCAAAGAATGTTGCCCAAGCCGTGCATAATTTGCAACCGTACA
TGCAGGTTGATCGCTTGATGGCGTTATCGCAATCAGAGCTGGAAACGTTGGTGCGACCAGCCGGCTTTTATCGGCAAAAA
GCGCAGCGGATTCACGATCTATTGACGTGGTTTGTGGCCCAAGGCGGTAGTTTTGAGAAGATTGCAGAAAAACCGGCAGC
TGAGTTACGTGAAACTCTGCTGGCTCTAAATGGCATTGGCAATGAAACGGCGGATGTCATGCTAATGTACACCTTTGGCA
AAAAAACTTTTGTAGCTGATACGTATGCCATGCGTCTTTTCAACCGGCTCGGTTTTGGACCGTATACGAACTATGCCAAA
ATGCAGGCTGATTTTGCGCCAGCACTTGATCAAATCACGTTAGACGAAGCTCGCGAATGGCATGCCTTGATTGACGAACA
TGGTAAAACGCAAGTTCGGCATGCGTATGACGACCGGTTTTTACTGCAGCCAGATTTGACTGAGGCGGCATGGCCGCCGG
AAGCGGTTCAAGTAGAGCCGCCCCATGATGATCCGGGTAGCGGCAAGTGGCGGCACGCCGCCGATCCGTCAGCGATGACT
CATAAATAA

Upstream 100 bases:

>100_bases
TAACAGGACTGCGCCGCGTTTTGCAAAAACTGCTGATAGGACCAGTTTACTTTATTTTTAGAAGAATGTGCGATATTAAT
AGGGGAATAGGGGTGAAAAG

Downstream 100 bases:

>100_bases
ATGCTTTTTGCTCGTGAGTTGTTTTGGCAATCTTGTCACAAGGGAGACCTAAAAATGAATGCTAGCGTTGCTGTGCAAGT
GTTACCGATGTATCCAGAGA

Product: endonuclease III-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MDKRLIVMHNLSRHYGKQYWWQQNSLEDWLMMILIQRTSSKNVAQAVHNLQPYMQVDRLMALSQSELETLVRPAGFYRQK
AQRIHDLLTWFVAQGGSFEKIAEKPAAELRETLLALNGIGNETADVMLMYTFGKKTFVADTYAMRLFNRLGFGPYTNYAK
MQADFAPALDQITLDEAREWHALIDEHGKTQVRHAYDDRFLLQPDLTEAAWPPEAVQVEPPHDDPGSGKWRHAADPSAMT
HK

Sequences:

>Translated_242_residues
MDKRLIVMHNLSRHYGKQYWWQQNSLEDWLMMILIQRTSSKNVAQAVHNLQPYMQVDRLMALSQSELETLVRPAGFYRQK
AQRIHDLLTWFVAQGGSFEKIAEKPAAELRETLLALNGIGNETADVMLMYTFGKKTFVADTYAMRLFNRLGFGPYTNYAK
MQADFAPALDQITLDEAREWHALIDEHGKTQVRHAYDDRFLLQPDLTEAAWPPEAVQVEPPHDDPGSGKWRHAADPSAMT
HK
>Mature_242_residues
MDKRLIVMHNLSRHYGKQYWWQQNSLEDWLMMILIQRTSSKNVAQAVHNLQPYMQVDRLMALSQSELETLVRPAGFYRQK
AQRIHDLLTWFVAQGGSFEKIAEKPAAELRETLLALNGIGNETADVMLMYTFGKKTFVADTYAMRLFNRLGFGPYTNYAK
MQADFAPALDQITLDEAREWHALIDEHGKTQVRHAYDDRFLLQPDLTEAAWPPEAVQVEPPHDDPGSGKWRHAADPSAMT
HK

Specific function: Has Both An Apurinic And/Or Apyrimidinic Endonuclease Activity And A DNA N-Glycosylase Activity. Incises Damaged DNA At Cytosines, Thymines And Guanines. Acts On A Damaged Strand, 5' From The Damaged Site. Required For The Repair Of Both Oxidative DNA Da

COG id: COG2231

COG function: function code L; Uncharacterized protein related to Endonuclease III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Nth/MutY family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003651
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: 4.2.99.18

Molecular weight: Translated: 27887; Mature: 27887

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKRLIVMHNLSRHYGKQYWWQQNSLEDWLMMILIQRTSSKNVAQAVHNLQPYMQVDRLM
CCCCEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ALSQSELETLVRPAGFYRQKAQRIHDLLTWFVAQGGSFEKIAEKPAAELRETLLALNGIG
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHCCC
NETADVMLMYTFGKKTFVADTYAMRLFNRLGFGPYTNYAKMQADFAPALDQITLDEAREW
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
HALIDEHGKTQVRHAYDDRFLLQPDLTEAAWPPEAVQVEPPHDDPGSGKWRHAADPSAMT
HHHHHHCCCHHHHHHCCCCEEECCCCCHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCC
HK
CC
>Mature Secondary Structure
MDKRLIVMHNLSRHYGKQYWWQQNSLEDWLMMILIQRTSSKNVAQAVHNLQPYMQVDRLM
CCCCEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ALSQSELETLVRPAGFYRQKAQRIHDLLTWFVAQGGSFEKIAEKPAAELRETLLALNGIG
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHCCC
NETADVMLMYTFGKKTFVADTYAMRLFNRLGFGPYTNYAKMQADFAPALDQITLDEAREW
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
HALIDEHGKTQVRHAYDDRFLLQPDLTEAAWPPEAVQVEPPHDDPGSGKWRHAADPSAMT
HHHHHHCCCHHHHHHCCCCEEECCCCCHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCC
HK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: 4Fe-4S Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyase [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]