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The map label for this gene is ziaR [H]

Identifier: 116493696

GI number: 116493696

Start: 121653

End: 122003

Strand: Direct

Name: ziaR [H]

Synonym: LSEI_0124

Alternate gene names: 116493696

Gene position: 121653-122003 (Clockwise)

Preceding gene: 116493695

Following gene: 116493698

Centisome position: 4.2

GC content: 50.14

Gene sequence:

>351_bases
ATGACAACTAATGATGTTCGTAATGCGGACATGAATGAGAACGCGGTGCCTAGTGACGCCGAATTGCGGGATGTGCTTGA
TGTGTTTAAAACCATGAGTGACCCGACCCGCATGCGGATTATTCTTGCTATTGCCAAGGGGCCAATTACAGTCACCGATC
TGGCCGCCATGCTCGACCTCGGTCAGTCAGCGGTTTCCCACCAACTGCGCCTGCTCAAACAAGCGCGGTTGGTTGTGGGG
GATCGCTCCGGCAAACAGATTTATTATCATTTGGTGGATGACCATGTTTTGGAAATCTACGCGCTGACGAAAGCGCACAT
TGAAGAAAAGCAGCATGGACAAGAAAATTAG

Upstream 100 bases:

>100_bases
GCTTAAGGGAAAACTGCCGACATCCGCCCTCAGTGAAAAGTGCCTTTCGATACCAAAGTCTGTTAAAATGGGCCATAAGT
ATCTTAAGGAGCGCAGTGCT

Downstream 100 bases:

>100_bases
TCATTGCTTATTTTAAAAGCACACAAAAACCACCAGTCCGAATTTGAAGCGGATCGGTGGTTTTTTGGTAAACAAAGCAC
GCATTATCATGCAATCTTTA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 116; Mature: 115

Protein sequence:

>116_residues
MTTNDVRNADMNENAVPSDAELRDVLDVFKTMSDPTRMRIILAIAKGPITVTDLAAMLDLGQSAVSHQLRLLKQARLVVG
DRSGKQIYYHLVDDHVLEIYALTKAHIEEKQHGQEN

Sequences:

>Translated_116_residues
MTTNDVRNADMNENAVPSDAELRDVLDVFKTMSDPTRMRIILAIAKGPITVTDLAAMLDLGQSAVSHQLRLLKQARLVVG
DRSGKQIYYHLVDDHVLEIYALTKAHIEEKQHGQEN
>Mature_115_residues
TTNDVRNADMNENAVPSDAELRDVLDVFKTMSDPTRMRIILAIAKGPITVTDLAAMLDLGQSAVSHQLRLLKQARLVVGD
RSGKQIYYHLVDDHVLEIYALTKAHIEEKQHGQEN

Specific function: Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ziaA-mediated efflux of excess zinc into the periplasm [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12995; Mature: 12864

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNDVRNADMNENAVPSDAELRDVLDVFKTMSDPTRMRIILAIAKGPITVTDLAAMLDL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHH
GQSAVSHQLRLLKQARLVVGDRSGKQIYYHLVDDHVLEIYALTKAHIEEKQHGQEN
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTNDVRNADMNENAVPSDAELRDVLDVFKTMSDPTRMRIILAIAKGPITVTDLAAMLDL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHH
GQSAVSHQLRLLKQARLVVGDRSGKQIYYHLVDDHVLEIYALTKAHIEEKQHGQEN
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9724772 [H]