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The map label for this gene is asd [H]

Identifier: 116493673

GI number: 116493673

Start: 95459

End: 96517

Strand: Direct

Name: asd [H]

Synonym: LSEI_0101

Alternate gene names: 116493673

Gene position: 95459-96517 (Clockwise)

Preceding gene: 116493672

Following gene: 116493675

Centisome position: 3.3

GC content: 48.82

Gene sequence:

>1059_bases
ATGAGAGGTTATCACGTAGCAGTTGTTGGGACTACTGGAGCTGTTGGCACCCGGATGTTAAAAATGGTGGCAGAAAGTAA
ACTGCCGATTGCGTCTGTCTTGGCACTTGCCAGCAAGCGCTCAGAAGGAAAGCAAGTCCCTTACCGTGATGGGACGCTGA
CCGTCCATGAGACGACCGATGATTCATTCAAGGGCATTGATATTGCCTTATTTTCTGCTGGCGGTTCAGTTTCCAAGCGA
TTTGCACCAGCCGCGGTTAAAGCTGGGGCTATCGTGGTTGATAATACGAGTGCTTTTCGAATGGAACCAGAAATTCCGCT
GGTTGTCCCAGAAGTGAATCCGGAAGCGTTGCGGCAACACAGTGGGATCATTGCAAATCCAAACTGTTCGACGATTCAAA
TGGTCACTGCGCTTGAACCGATTCGGAAAGCCTTTGGTCTTAAACAAGTGGTCGTTTCGACCTATCAGGCTGTTTCTGGC
GCTGGACAATCAGCTGTGAATGAATTGCTTGATGAAACTCGCGCTGCATTGGACGACAAACCGCTTGACCCGCAGATTTT
ACCAACGGCGGGTGACAAGAAACATTATCCGATCGCCTTCAATGCCTTGCCGCAAATCGATGTTTTCGAACCGGATGGCT
ATAGCCATGAAGAATGGAAAATGATCCACGAAACCAAGAAAATCATGGCTGGGGATATGAATAGCGACACCATCAAAGTG
ACCGCAACCTGTGTTCGAATTCCGGTGCCAATTGCCCACTCTGAAGAAGTGTACTTCGAAGTCGAAGACGACAAGGCAAC
TGCCGATGATATTCGCGAGGCATTGGCGCATGCTCCTGGTGTCGTTGTTCAAGACGACCCAAGCAAACAAGTGTATCCGC
AAGCGATGAACGCCGTTGGCAGCAAAGATGTTTTCGTTGGCCGCATTCGGCCAGATGCAGAAAACCCACGATTCTTCCAT
ATGTGGAATGTTTCTGACAATTTATTGAAAGGCGCTGCTTGGAATTCCATGCAGATTGCTGAAACGATGGATGCCATGGG
ACTCATTCAACCTAAGTAA

Upstream 100 bases:

>100_bases
TGAGATTCACGCGACTGGCGAACAGGCTGAGTATGAACGATTTATTGACGCACTGCCGCATCGGAAGTTAGCAAACACAT
TGACAGAAGGAGTTTAGATC

Downstream 100 bases:

>100_bases
ATCGTTCGGTAAAAAAACCGGTATCATCATTGTTCAGGAGGTTCTGAACAGCGACGATGACGGCTTTTTTATTGCTTTGA
GATTGTTCAAAAATAACACC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MRGYHVAVVGTTGAVGTRMLKMVAESKLPIASVLALASKRSEGKQVPYRDGTLTVHETTDDSFKGIDIALFSAGGSVSKR
FAPAAVKAGAIVVDNTSAFRMEPEIPLVVPEVNPEALRQHSGIIANPNCSTIQMVTALEPIRKAFGLKQVVVSTYQAVSG
AGQSAVNELLDETRAALDDKPLDPQILPTAGDKKHYPIAFNALPQIDVFEPDGYSHEEWKMIHETKKIMAGDMNSDTIKV
TATCVRIPVPIAHSEEVYFEVEDDKATADDIREALAHAPGVVVQDDPSKQVYPQAMNAVGSKDVFVGRIRPDAENPRFFH
MWNVSDNLLKGAAWNSMQIAETMDAMGLIQPK

Sequences:

>Translated_352_residues
MRGYHVAVVGTTGAVGTRMLKMVAESKLPIASVLALASKRSEGKQVPYRDGTLTVHETTDDSFKGIDIALFSAGGSVSKR
FAPAAVKAGAIVVDNTSAFRMEPEIPLVVPEVNPEALRQHSGIIANPNCSTIQMVTALEPIRKAFGLKQVVVSTYQAVSG
AGQSAVNELLDETRAALDDKPLDPQILPTAGDKKHYPIAFNALPQIDVFEPDGYSHEEWKMIHETKKIMAGDMNSDTIKV
TATCVRIPVPIAHSEEVYFEVEDDKATADDIREALAHAPGVVVQDDPSKQVYPQAMNAVGSKDVFVGRIRPDAENPRFFH
MWNVSDNLLKGAAWNSMQIAETMDAMGLIQPK
>Mature_352_residues
MRGYHVAVVGTTGAVGTRMLKMVAESKLPIASVLALASKRSEGKQVPYRDGTLTVHETTDDSFKGIDIALFSAGGSVSKR
FAPAAVKAGAIVVDNTSAFRMEPEIPLVVPEVNPEALRQHSGIIANPNCSTIQMVTALEPIRKAFGLKQVVVSTYQAVSG
AGQSAVNELLDETRAALDDKPLDPQILPTAGDKKHYPIAFNALPQIDVFEPDGYSHEEWKMIHETKKIMAGDMNSDTIKV
TATCVRIPVPIAHSEEVYFEVEDDKATADDIREALAHAPGVVVQDDPSKQVYPQAMNAVGSKDVFVGRIRPDAENPRFFH
MWNVSDNLLKGAAWNSMQIAETMDAMGLIQPK

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=343, Percent_Identity=30.3206997084548, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1789841, Length=360, Percent_Identity=27.2222222222222, Blast_Score=93, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320362, Length=408, Percent_Identity=29.4117647058824, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 38133; Mature: 38133

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGYHVAVVGTTGAVGTRMLKMVAESKLPIASVLALASKRSEGKQVPYRDGTLTVHETTD
CCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCC
DSFKGIDIALFSAGGSVSKRFAPAAVKAGAIVVDNTSAFRMEPEIPLVVPEVNPEALRQH
CCCCCEEEEEEECCCCCHHHCCCHHHCCCEEEEECCCCEEECCCCCEEEECCCHHHHHHC
SGIIANPNCSTIQMVTALEPIRKAFGLKQVVVSTYQAVSGAGQSAVNELLDETRAALDDK
CCEEECCCCCEEEHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
PLDPQILPTAGDKKHYPIAFNALPQIDVFEPDGYSHEEWKMIHETKKIMAGDMNSDTIKV
CCCCCEECCCCCCCCCCEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEE
TATCVRIPVPIAHSEEVYFEVEDDKATADDIREALAHAPGVVVQDDPSKQVYPQAMNAVG
EEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHCCC
SKDVFVGRIRPDAENPRFFHMWNVSDNLLKGAAWNSMQIAETMDAMGLIQPK
CCCEEEEEECCCCCCCCEEEEECCCHHHHCCCCCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRGYHVAVVGTTGAVGTRMLKMVAESKLPIASVLALASKRSEGKQVPYRDGTLTVHETTD
CCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCC
DSFKGIDIALFSAGGSVSKRFAPAAVKAGAIVVDNTSAFRMEPEIPLVVPEVNPEALRQH
CCCCCEEEEEEECCCCCHHHCCCHHHCCCEEEEECCCCEEECCCCCEEEECCCHHHHHHC
SGIIANPNCSTIQMVTALEPIRKAFGLKQVVVSTYQAVSGAGQSAVNELLDETRAALDDK
CCEEECCCCCEEEHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
PLDPQILPTAGDKKHYPIAFNALPQIDVFEPDGYSHEEWKMIHETKKIMAGDMNSDTIKV
CCCCCEECCCCCCCCCCEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEE
TATCVRIPVPIAHSEEVYFEVEDDKATADDIREALAHAPGVVVQDDPSKQVYPQAMNAVG
EEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHCCC
SKDVFVGRIRPDAENPRFFHMWNVSDNLLKGAAWNSMQIAETMDAMGLIQPK
CCCEEEEEECCCCCCCCEEEEECCCHHHHCCCCCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8098035; 9384377; 8345520 [H]