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The map label for this gene is treA [H]

Identifier: 116493533

GI number: 116493533

Start: 1785154

End: 1786800

Strand: Direct

Name: treA [H]

Synonym: PEPE_1806

Alternate gene names: 116493533

Gene position: 1785154-1786800 (Clockwise)

Preceding gene: 116493532

Following gene: 116493535

Centisome position: 97.42

GC content: 37.52

Gene sequence:

>1647_bases
ATGAATTTTAAAAATAAGGTTATTTACCAAATTTATCCCAAATCATTCTATGATTCTAACAACGATGGCATTGGAGATTT
ACAAGGAATTATCAAAAAAATTCCTTATATTGATAAGTTGAATATCGATATGATTTGGTTCAATCCTTTTTTCGTTTCTC
CTCAATACGATAATGGTTATGACATTGCCAATTTCTATGAAATTGACCCTGTCTTTGGTACGATGTCAGCTTTTGAAGAA
TTAGTCCGTAAATTAAAGGAAATCCATGTCGGAGTTATGCTAGATATGGTGTTAAATCATATTTCTACTGAGCATGAATG
GTTTCAAAAAGCCTTAGCTGGCGACGAACACTATCAAAAATACTTCTACATTCGAGATCCTAAACCAAATGGTGATTTAC
CCAACAATTGGACTTCTAAATTTGGTGGACCAGCTTGGGCTAAATTTGGTGATACCGGTAAATATTTCTTACACTTATAC
GACGAGCATCAAGCCGATCTTGACTGGCATAACCCTGAAGTTCGCCAAGAACTTTTCAAGGTCATTAATTTTTGGCATGC
CAAGGGGGTTAAGGGATTCCGCTTTGATGTAATTAATGTGACTGGAAAGGACGTAGAGTTAACCGACGCTCCTGAAGGCG
TAGAATCAAAATTTATGTATACCGATACACCTATCGTTCAAAGTTATCTTAAGGAAATGCATCAAGCTGCACTTCAAGAC
CCTGAAGTAATTACCGTAGGAGAGTTTTCTTCAGCTTCAGTTGAAAATGGTGTGAAATATACTCGTCCGGAAGAACATGA
ATTAACCATGGCTTTCACCTTCCACCATTTAAAAGTAGATTACGACCACGGACAAAAATGGACGAAAGTTCCTTTTGACT
TTGCTGCACTTAAAAAGACGATAAATACTTGGCAAGTGGGCATGGATGAAGGTGATGGATGGAACGCCCTCTTCTGGAAT
AATCACGATCAGCCTTGGGCCTTAAATCGCTTTGGAGATTCTGGTAAATACCGAGCTAAGTCTGCCGAAATGCTTGCCAC
CACGATGCATTTGCTTCGTGGAACGCCCTATATTTATCAGGGAGAAGAAATCGGCATGGTCGATCCAGATTACCAAAACA
TTGACGAATATGTTGATGTAGAAGCCTTAAACGCTTATCAACGACTCTTGAAAGAAAATAAATCTCCTCAAGATGCACTT
GAAATCGTGAAGTCTAAAGCTCGCGATAATAGTCGAGTTCCTATGCATTGGGATGATTCCAAATATGCTGGCTTTTCTGA
AGTTCAACCTTGGTTAAAACCAACTAAGCAAACTGAAATTAACGTTGCAAATGAACTAGAACACGGTGAAATTTTTGCTT
ATTACCAAAAATTAATTCAACTTCGCCGAGAATTCTCCATTATTTCTGAAGGAGATTATCAATCCTTTGAACTTAATCAC
CCTTCTGTATTCGCTTATATTCGTACCTATCAAGACCAAAGCTTGTTGGTTCTCAATAACTTCTATGGAAATGATGCTAC
CATCTCAATTCCTAGTAAATACACCACTGAAACTGCTAAAATCTTGATTAACAACTACGAGACTAATCCTGAATTAACAA
CAACGCTGAAATTGAAACCTTATCAATCCATAGCAATTCTGATTTAG

Upstream 100 bases:

>100_bases
ATGACACCACGTTGTTCCAATTTACCGAATCTATTCATCGAGCTGATAAATTTAGTTTTGTTGATTTTGCTAGAAGACAA
AAATTGAAAGGACACTAACT

Downstream 100 bases:

>100_bases
TGCAATAAAATAAGTCCTTCAAGTTAACTAAGTAGCTTGAAGGACTTTTATTATCTAGCATTAATTTTAATTTCATGTTT
ATACTTGCACCAATAAATAT

Product: alpha, alpha-phosphotrehalase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MNFKNKVIYQIYPKSFYDSNNDGIGDLQGIIKKIPYIDKLNIDMIWFNPFFVSPQYDNGYDIANFYEIDPVFGTMSAFEE
LVRKLKEIHVGVMLDMVLNHISTEHEWFQKALAGDEHYQKYFYIRDPKPNGDLPNNWTSKFGGPAWAKFGDTGKYFLHLY
DEHQADLDWHNPEVRQELFKVINFWHAKGVKGFRFDVINVTGKDVELTDAPEGVESKFMYTDTPIVQSYLKEMHQAALQD
PEVITVGEFSSASVENGVKYTRPEEHELTMAFTFHHLKVDYDHGQKWTKVPFDFAALKKTINTWQVGMDEGDGWNALFWN
NHDQPWALNRFGDSGKYRAKSAEMLATTMHLLRGTPYIYQGEEIGMVDPDYQNIDEYVDVEALNAYQRLLKENKSPQDAL
EIVKSKARDNSRVPMHWDDSKYAGFSEVQPWLKPTKQTEINVANELEHGEIFAYYQKLIQLRREFSIISEGDYQSFELNH
PSVFAYIRTYQDQSLLVLNNFYGNDATISIPSKYTTETAKILINNYETNPELTTTLKLKPYQSIAILI

Sequences:

>Translated_548_residues
MNFKNKVIYQIYPKSFYDSNNDGIGDLQGIIKKIPYIDKLNIDMIWFNPFFVSPQYDNGYDIANFYEIDPVFGTMSAFEE
LVRKLKEIHVGVMLDMVLNHISTEHEWFQKALAGDEHYQKYFYIRDPKPNGDLPNNWTSKFGGPAWAKFGDTGKYFLHLY
DEHQADLDWHNPEVRQELFKVINFWHAKGVKGFRFDVINVTGKDVELTDAPEGVESKFMYTDTPIVQSYLKEMHQAALQD
PEVITVGEFSSASVENGVKYTRPEEHELTMAFTFHHLKVDYDHGQKWTKVPFDFAALKKTINTWQVGMDEGDGWNALFWN
NHDQPWALNRFGDSGKYRAKSAEMLATTMHLLRGTPYIYQGEEIGMVDPDYQNIDEYVDVEALNAYQRLLKENKSPQDAL
EIVKSKARDNSRVPMHWDDSKYAGFSEVQPWLKPTKQTEINVANELEHGEIFAYYQKLIQLRREFSIISEGDYQSFELNH
PSVFAYIRTYQDQSLLVLNNFYGNDATISIPSKYTTETAKILINNYETNPELTTTLKLKPYQSIAILI
>Mature_548_residues
MNFKNKVIYQIYPKSFYDSNNDGIGDLQGIIKKIPYIDKLNIDMIWFNPFFVSPQYDNGYDIANFYEIDPVFGTMSAFEE
LVRKLKEIHVGVMLDMVLNHISTEHEWFQKALAGDEHYQKYFYIRDPKPNGDLPNNWTSKFGGPAWAKFGDTGKYFLHLY
DEHQADLDWHNPEVRQELFKVINFWHAKGVKGFRFDVINVTGKDVELTDAPEGVESKFMYTDTPIVQSYLKEMHQAALQD
PEVITVGEFSSASVENGVKYTRPEEHELTMAFTFHHLKVDYDHGQKWTKVPFDFAALKKTINTWQVGMDEGDGWNALFWN
NHDQPWALNRFGDSGKYRAKSAEMLATTMHLLRGTPYIYQGEEIGMVDPDYQNIDEYVDVEALNAYQRLLKENKSPQDAL
EIVKSKARDNSRVPMHWDDSKYAGFSEVQPWLKPTKQTEINVANELEHGEIFAYYQKLIQLRREFSIISEGDYQSFELNH
PSVFAYIRTYQDQSLLVLNNFYGNDATISIPSKYTTETAKILINNYETNPELTTTLKLKPYQSIAILI

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=450, Percent_Identity=29.3333333333333, Blast_Score=177, Evalue=2e-44,
Organism=Escherichia coli, GI1790687, Length=544, Percent_Identity=43.75, Blast_Score=478, Evalue=1e-136,
Organism=Escherichia coli, GI1786604, Length=185, Percent_Identity=25.9459459459459, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25147709, Length=496, Percent_Identity=24.1935483870968, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI32565753, Length=203, Percent_Identity=27.5862068965517, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322245, Length=578, Percent_Identity=32.1799307958478, Blast_Score=298, Evalue=2e-81,
Organism=Saccharomyces cerevisiae, GI6321731, Length=576, Percent_Identity=32.9861111111111, Blast_Score=297, Evalue=4e-81,
Organism=Saccharomyces cerevisiae, GI6319776, Length=576, Percent_Identity=32.8125, Blast_Score=296, Evalue=7e-81,
Organism=Saccharomyces cerevisiae, GI6321726, Length=570, Percent_Identity=32.4561403508772, Blast_Score=291, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6322241, Length=570, Percent_Identity=32.280701754386, Blast_Score=283, Evalue=7e-77,
Organism=Saccharomyces cerevisiae, GI6322021, Length=570, Percent_Identity=32.280701754386, Blast_Score=283, Evalue=7e-77,
Organism=Saccharomyces cerevisiae, GI6324416, Length=570, Percent_Identity=32.280701754386, Blast_Score=281, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24586593, Length=581, Percent_Identity=30.8089500860585, Blast_Score=232, Evalue=6e-61,
Organism=Drosophila melanogaster, GI24583747, Length=548, Percent_Identity=31.3868613138686, Blast_Score=229, Evalue=3e-60,
Organism=Drosophila melanogaster, GI24583749, Length=548, Percent_Identity=31.3868613138686, Blast_Score=229, Evalue=3e-60,
Organism=Drosophila melanogaster, GI24586591, Length=509, Percent_Identity=31.6306483300589, Blast_Score=218, Evalue=7e-57,
Organism=Drosophila melanogaster, GI24583745, Length=579, Percent_Identity=29.706390328152, Blast_Score=218, Evalue=9e-57,
Organism=Drosophila melanogaster, GI221330053, Length=575, Percent_Identity=28, Blast_Score=213, Evalue=3e-55,
Organism=Drosophila melanogaster, GI24586589, Length=546, Percent_Identity=29.4871794871795, Blast_Score=211, Evalue=8e-55,
Organism=Drosophila melanogaster, GI45549022, Length=572, Percent_Identity=30.2447552447552, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24586597, Length=541, Percent_Identity=28.0961182994455, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24586599, Length=577, Percent_Identity=28.7694974003466, Blast_Score=198, Evalue=7e-51,
Organism=Drosophila melanogaster, GI24586587, Length=597, Percent_Identity=29.8157453936348, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI281360393, Length=527, Percent_Identity=29.0322580645161, Blast_Score=171, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 63684; Mature: 63684

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFKNKVIYQIYPKSFYDSNNDGIGDLQGIIKKIPYIDKLNIDMIWFNPFFVSPQYDNGY
CCCCCCEEEEECCHHHCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECEEEECCCCCCCC
DIANFYEIDPVFGTMSAFEELVRKLKEIHVGVMLDMVLNHISTEHEWFQKALAGDEHYQK
CCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEE
YFYIRDPKPNGDLPNNWTSKFGGPAWAKFGDTGKYFLHLYDEHQADLDWHNPEVRQELFK
EEEEECCCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHH
VINFWHAKGVKGFRFDVINVTGKDVELTDAPEGVESKFMYTDTPIVQSYLKEMHQAALQD
HHHHHHHCCCCCEEEEEEEECCCCEEECCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCC
PEVITVGEFSSASVENGVKYTRPEEHELTMAFTFHHLKVDYDHGQKWTKVPFDFAALKKT
CCEEEECCCCCCHHHCCCCCCCCCCCEEEEEEEEEEEEEECCCCCCEECCCCHHHHHHHH
INTWQVGMDEGDGWNALFWNNHDQPWALNRFGDSGKYRAKSAEMLATTMHLLRGTPYIYQ
HHHHEEECCCCCCCEEEEECCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEE
GEEIGMVDPDYQNIDEYVDVEALNAYQRLLKENKSPQDALEIVKSKARDNSRVPMHWDDS
CCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEECCC
KYAGFSEVQPWLKPTKQTEINVANELEHGEIFAYYQKLIQLRREFSIISEGDYQSFELNH
CCCCHHHCCHHHCCCCCCEEEHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCC
PSVFAYIRTYQDQSLLVLNNFYGNDATISIPSKYTTETAKILINNYETNPELTTTLKLKP
CEEEEEEEECCCCEEEEEEECCCCCEEEECCCCCCCCEEEEEEECCCCCCCEEEEEEECC
YQSIAILI
CCCEEEEC
>Mature Secondary Structure
MNFKNKVIYQIYPKSFYDSNNDGIGDLQGIIKKIPYIDKLNIDMIWFNPFFVSPQYDNGY
CCCCCCEEEEECCHHHCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECEEEECCCCCCCC
DIANFYEIDPVFGTMSAFEELVRKLKEIHVGVMLDMVLNHISTEHEWFQKALAGDEHYQK
CCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEE
YFYIRDPKPNGDLPNNWTSKFGGPAWAKFGDTGKYFLHLYDEHQADLDWHNPEVRQELFK
EEEEECCCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHH
VINFWHAKGVKGFRFDVINVTGKDVELTDAPEGVESKFMYTDTPIVQSYLKEMHQAALQD
HHHHHHHCCCCCEEEEEEEECCCCEEECCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCC
PEVITVGEFSSASVENGVKYTRPEEHELTMAFTFHHLKVDYDHGQKWTKVPFDFAALKKT
CCEEEECCCCCCHHHCCCCCCCCCCCEEEEEEEEEEEEEECCCCCCEECCCCHHHHHHHH
INTWQVGMDEGDGWNALFWNNHDQPWALNRFGDSGKYRAKSAEMLATTMHLLRGTPYIYQ
HHHHEEECCCCCCCEEEEECCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEE
GEEIGMVDPDYQNIDEYVDVEALNAYQRLLKENKSPQDALEIVKSKARDNSRVPMHWDDS
CCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEECCC
KYAGFSEVQPWLKPTKQTEINVANELEHGEIFAYYQKLIQLRREFSIISEGDYQSFELNH
CCCCHHHCCHHHCCCCCCEEEHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCC
PSVFAYIRTYQDQSLLVLNNFYGNDATISIPSKYTTETAKILINNYETNPELTTTLKLKP
CEEEEEEEECCCCEEEEEEECCCCCEEEECCCCCCCCEEEEEEECCCCCCCEEEEEEECC
YQSIAILI
CCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7651129; 8969503; 9384377; 7751281 [H]