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The map label for this gene is gpmA1 [H]

Identifier: 116493248

GI number: 116493248

Start: 1477164

End: 1477844

Strand: Reverse

Name: gpmA1 [H]

Synonym: PEPE_1510

Alternate gene names: 116493248

Gene position: 1477844-1477164 (Counterclockwise)

Preceding gene: 116493249

Following gene: 116493247

Centisome position: 80.65

GC content: 38.47

Gene sequence:

>681_bases
TTGGCTAAATTAGTTTTAATTAGGCATGGGGAAAGTACCGCCAATCGTGATAATATTTATACAGGGTGGTCGGATGTTCC
GCTTACTCCGCTTGGTATTAAGCAAGCACAACGAGCAGGAAAATTAATTGCTAAATTAGGAATTAATTTTGATATGGTTC
ACACTTCAATGCTGAAGCGCGCGATTGTGACTGCTAATATCGTTTTAGATGATCTTAATCAAAATTGGTTACCGATTAAT
AAGACTTGGCGATTAAATGAACGCCATTATGGGGCTTTAAGGGGACAAAATAAGGATGAGACCCGCCAAATTTATGGTAA
GGAGCAGGTTGCTTTATGGCGTCGGAGTTTTGATGCAGTACCACCCCTGCTAGAGCATCCCGATGATGATCGACGATATG
CGGTTAATGGAATTTTGAATGAACCACTGGGTGAAAGTTTACATATGGCTTATAATCGCTTGCTACCATACTGGATTGAT
CAAATTGCTCCTAGATTAATGGAAGGACAAAATCAATTGGTAGTCGCACATGGAAGTTCTTTGCGAGCATTAATTAAATA
TTTGGAGAACATTTCTGACCAGGGTATTGATGGAGTCGAAGTTGAAAATGGAGAACCCATCATTTACGAATTAAAATCGG
ATTTATCTATCCAAAATAAAATTATCTTGAAAGAAGCCTAA

Upstream 100 bases:

>100_bases
TTTAATGGGATTAAGACTTGCAACTAGTTAGAAAATGAATAACAATGAAGTAGAGTTGAACGATAAGATTGAATTAATAT
TGAGCAGGGAGAGAAAAGAA

Downstream 100 bases:

>100_bases
TTATTTAGGCTCTTTTTTTATGCATAAAGTATTGATTTCAGTAAAATGGGACAATTTTGTCTCTATGCGACAAAATTGTG
CGTACTTCTATAAATGTCAT

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: BPG-dependent PGAM 1; PGAM 1; Phosphoglyceromutase 1; dPGM 1 [H]

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MAKLVLIRHGESTANRDNIYTGWSDVPLTPLGIKQAQRAGKLIAKLGINFDMVHTSMLKRAIVTANIVLDDLNQNWLPIN
KTWRLNERHYGALRGQNKDETRQIYGKEQVALWRRSFDAVPPLLEHPDDDRRYAVNGILNEPLGESLHMAYNRLLPYWID
QIAPRLMEGQNQLVVAHGSSLRALIKYLENISDQGIDGVEVENGEPIIYELKSDLSIQNKIILKEA

Sequences:

>Translated_226_residues
MAKLVLIRHGESTANRDNIYTGWSDVPLTPLGIKQAQRAGKLIAKLGINFDMVHTSMLKRAIVTANIVLDDLNQNWLPIN
KTWRLNERHYGALRGQNKDETRQIYGKEQVALWRRSFDAVPPLLEHPDDDRRYAVNGILNEPLGESLHMAYNRLLPYWID
QIAPRLMEGQNQLVVAHGSSLRALIKYLENISDQGIDGVEVENGEPIIYELKSDLSIQNKIILKEA
>Mature_225_residues
AKLVLIRHGESTANRDNIYTGWSDVPLTPLGIKQAQRAGKLIAKLGINFDMVHTSMLKRAIVTANIVLDDLNQNWLPINK
TWRLNERHYGALRGQNKDETRQIYGKEQVALWRRSFDAVPPLLEHPDDDRRYAVNGILNEPLGESLHMAYNRLLPYWIDQ
IAPRLMEGQNQLVVAHGSSLRALIKYLENISDQGIDGVEVENGEPIIYELKSDLSIQNKIILKEA

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=220, Percent_Identity=45.9090909090909, Blast_Score=201, Evalue=3e-52,
Organism=Homo sapiens, GI4502445, Length=222, Percent_Identity=44.5945945945946, Blast_Score=192, Evalue=1e-49,
Organism=Homo sapiens, GI40353764, Length=222, Percent_Identity=44.5945945945946, Blast_Score=192, Evalue=1e-49,
Organism=Homo sapiens, GI4505753, Length=220, Percent_Identity=45, Blast_Score=190, Evalue=1e-48,
Organism=Homo sapiens, GI71274132, Length=220, Percent_Identity=43.1818181818182, Blast_Score=178, Evalue=4e-45,
Organism=Homo sapiens, GI310129614, Length=161, Percent_Identity=46.583850931677, Blast_Score=136, Evalue=1e-32,
Organism=Escherichia coli, GI1786970, Length=231, Percent_Identity=46.7532467532467, Blast_Score=218, Evalue=3e-58,
Organism=Escherichia coli, GI1786857, Length=89, Percent_Identity=44.9438202247191, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322697, Length=222, Percent_Identity=44.1441441441441, Blast_Score=195, Evalue=6e-51,
Organism=Saccharomyces cerevisiae, GI6324516, Length=265, Percent_Identity=30.9433962264151, Blast_Score=122, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6320183, Length=266, Percent_Identity=30.8270676691729, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324857, Length=188, Percent_Identity=26.5957446808511, Blast_Score=66, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24646216, Length=221, Percent_Identity=42.0814479638009, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI85725270, Length=221, Percent_Identity=43.8914027149321, Blast_Score=180, Evalue=6e-46,
Organism=Drosophila melanogaster, GI85725272, Length=221, Percent_Identity=43.8914027149321, Blast_Score=180, Evalue=6e-46,
Organism=Drosophila melanogaster, GI24650981, Length=221, Percent_Identity=43.8914027149321, Blast_Score=180, Evalue=6e-46,
Organism=Drosophila melanogaster, GI28571815, Length=220, Percent_Identity=38.1818181818182, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI28571817, Length=220, Percent_Identity=38.1818181818182, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24648979, Length=220, Percent_Identity=38.1818181818182, Blast_Score=162, Evalue=2e-40,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 25727; Mature: 25596

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLVLIRHGESTANRDNIYTGWSDVPLTPLGIKQAQRAGKLIAKLGINFDMVHTSMLKR
CCEEEEEECCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AIVTANIVLDDLNQNWLPINKTWRLNERHYGALRGQNKDETRQIYGKEQVALWRRSFDAV
HHHHHHHEEECCCCCCCCCCCEEEECCCCCHHCCCCCHHHHHHHHCHHHHHHHHHHHHCC
PPLLEHPDDDRRYAVNGILNEPLGESLHMAYNRLLPYWIDQIAPRLMEGQNQLVVAHGSS
CHHHCCCCCCCEEEECCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHH
LRALIKYLENISDQGIDGVEVENGEPIIYELKSDLSIQNKIILKEA
HHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCCCCCCCEEEEECC
>Mature Secondary Structure 
AKLVLIRHGESTANRDNIYTGWSDVPLTPLGIKQAQRAGKLIAKLGINFDMVHTSMLKR
CEEEEEECCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AIVTANIVLDDLNQNWLPINKTWRLNERHYGALRGQNKDETRQIYGKEQVALWRRSFDAV
HHHHHHHEEECCCCCCCCCCCEEEECCCCCHHCCCCCHHHHHHHHCHHHHHHHHHHHHCC
PPLLEHPDDDRRYAVNGILNEPLGESLHMAYNRLLPYWIDQIAPRLMEGQNQLVVAHGSS
CHHHCCCCCCCEEEECCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHH
LRALIKYLENISDQGIDGVEVENGEPIIYELKSDLSIQNKIILKEA
HHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12566566 [H]