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The map label for this gene is fabH1 [H]

Identifier: 116493249

GI number: 116493249

Start: 1478016

End: 1478987

Strand: Reverse

Name: fabH1 [H]

Synonym: PEPE_1511

Alternate gene names: 116493249

Gene position: 1478987-1478016 (Counterclockwise)

Preceding gene: 116493251

Following gene: 116493248

Centisome position: 80.71

GC content: 37.96

Gene sequence:

>972_bases
ATGAGTTTAAAAATTTTATCTACAGCACATTATGTACCCGAACGGGTGGTTGATAACGATGAGTTATCCAAAATTATGGA
TACAAATGATGAGTGGATTCAATCCCACACAGGAATTCAAACTCGTCATTATGCCATGGGCGAAGAGAATACATCAAGCT
TAGCAGTCGAAGTGGGACAAAAATTATTAAACGAAAGTGGTTTAACGGCTGATCAAATCGATGTTATTATTCTTTCAACG
ATTACGCCAGACGCTTTAACTCCGGCTACTGCAACCATTGTGCAAGCTAAGTTAGGTGCCAAAAATGCTATTGCTTTTGA
TATATCGGCTGCTTGTGCTGGATTTGTTTTTGGGCTAAGTACGGCTGAAAAATTTATGCGTTCTGGACGTTACCGAAACG
CGATGGTGATTAGTGCGGAAACCAATTCTAAAATGATGGATTTTAAAGATCGGACCTCCGCAGTATTTTTTGGTGACGGA
GCGGGTGGTGTAATTATTTCTGCTGATGCGCATAACACAGAAGATTTCTTTATTGACGAAGAATTAGCCACCTTAGCGGA
AAAAAATGAGTATATTCATAGCGGCCGAATTCCGGCTTTAACGGCTGTGAAAGCTAATAACTTTCCAACAATCGACGCTT
TTTTCCAAAGTGGACGAGATGTTTTTAGTTTTGCTACCGGAGTAGTTCCTCCTCAAATGGTAGAAATTTTAAATCGAAAT
GATTTACATGATAAGGTTGATTACGTAATCTGTCATCAAGCTAACTTAAGAATTATTGAAAAGATTTCTGAAACGATTAA
CATTCCAATGGAAAAATTTGTTACGAATGTTGAACAATATGGAAATACTTCATCAGCTGGAATTCCAATGGCATTGGCTC
AACTCCAAGAAAAAGATCCTAATCCTAAAACTGTTTTAATGACTGGGTTTGGTGCGGGTCTGGACTATGGAAGTATGTTG
ATTAGAATTTAA

Upstream 100 bases:

>100_bases
GAAAACGTTTGTTAGATGTGATCTGTCACGCACACTATTTTCACAAATAATATTTTACTGGTAGAATAGAATGATAAACA
AAGTGAGGAAGAAGCTTAAA

Downstream 100 bases:

>100_bases
TCATTGGAATTAAAACTAAACTGTGGTTCGTAATGTGGACCACAGTTTTTTAGTATCTTCATGTAAAAAGTTTTAATGGG
ATTAAGACTTGCAACTAGTT

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III protein 1; Beta-ketoacyl-ACP synthase III 1; KAS III 1 [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MSLKILSTAHYVPERVVDNDELSKIMDTNDEWIQSHTGIQTRHYAMGEENTSSLAVEVGQKLLNESGLTADQIDVIILST
ITPDALTPATATIVQAKLGAKNAIAFDISAACAGFVFGLSTAEKFMRSGRYRNAMVISAETNSKMMDFKDRTSAVFFGDG
AGGVIISADAHNTEDFFIDEELATLAEKNEYIHSGRIPALTAVKANNFPTIDAFFQSGRDVFSFATGVVPPQMVEILNRN
DLHDKVDYVICHQANLRIIEKISETINIPMEKFVTNVEQYGNTSSAGIPMALAQLQEKDPNPKTVLMTGFGAGLDYGSML
IRI

Sequences:

>Translated_323_residues
MSLKILSTAHYVPERVVDNDELSKIMDTNDEWIQSHTGIQTRHYAMGEENTSSLAVEVGQKLLNESGLTADQIDVIILST
ITPDALTPATATIVQAKLGAKNAIAFDISAACAGFVFGLSTAEKFMRSGRYRNAMVISAETNSKMMDFKDRTSAVFFGDG
AGGVIISADAHNTEDFFIDEELATLAEKNEYIHSGRIPALTAVKANNFPTIDAFFQSGRDVFSFATGVVPPQMVEILNRN
DLHDKVDYVICHQANLRIIEKISETINIPMEKFVTNVEQYGNTSSAGIPMALAQLQEKDPNPKTVLMTGFGAGLDYGSML
IRI
>Mature_322_residues
SLKILSTAHYVPERVVDNDELSKIMDTNDEWIQSHTGIQTRHYAMGEENTSSLAVEVGQKLLNESGLTADQIDVIILSTI
TPDALTPATATIVQAKLGAKNAIAFDISAACAGFVFGLSTAEKFMRSGRYRNAMVISAETNSKMMDFKDRTSAVFFGDGA
GGVIISADAHNTEDFFIDEELATLAEKNEYIHSGRIPALTAVKANNFPTIDAFFQSGRDVFSFATGVVPPQMVEILNRND
LHDKVDYVICHQANLRIIEKISETINIPMEKFVTNVEQYGNTSSAGIPMALAQLQEKDPNPKTVLMTGFGAGLDYGSMLI
RI

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=325, Percent_Identity=33.2307692307692, Blast_Score=191, Evalue=5e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 35239; Mature: 35108

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKILSTAHYVPERVVDNDELSKIMDTNDEWIQSHTGIQTRHYAMGEENTSSLAVEVGQ
CCEEEEHHHHHCHHHHCCCHHHHHHHCCCHHHHHHCCCCCEEEEECCCCCCHHHHHHHHH
KLLNESGLTADQIDVIILSTITPDALTPATATIVQAKLGAKNAIAFDISAACAGFVFGLS
HHHHHCCCCHHHEEEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHH
TAEKFMRSGRYRNAMVISAETNSKMMDFKDRTSAVFFGDGAGGVIISADAHNTEDFFIDE
HHHHHHHCCCCCCEEEEEECCCCCEECCCCCCCEEEEECCCCCEEEEECCCCCCCEEECH
ELATLAEKNEYIHSGRIPALTAVKANNFPTIDAFFQSGRDVFSFATGVVPPQMVEILNRN
HHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHCCCHHHHHHHCCCCHHHHHHHCCC
DLHDKVDYVICHQANLRIIEKISETINIPMEKFVTNVEQYGNTSSAGIPMALAQLQEKDP
CCHHHHCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
NPKTVLMTGFGAGLDYGSMLIRI
CCCEEEEEECCCCCCCCCEEEEC
>Mature Secondary Structure 
SLKILSTAHYVPERVVDNDELSKIMDTNDEWIQSHTGIQTRHYAMGEENTSSLAVEVGQ
CEEEEHHHHHCHHHHCCCHHHHHHHCCCHHHHHHCCCCCEEEEECCCCCCHHHHHHHHH
KLLNESGLTADQIDVIILSTITPDALTPATATIVQAKLGAKNAIAFDISAACAGFVFGLS
HHHHHCCCCHHHEEEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHH
TAEKFMRSGRYRNAMVISAETNSKMMDFKDRTSAVFFGDGAGGVIISADAHNTEDFFIDE
HHHHHHHCCCCCCEEEEEECCCCCEECCCCCCCEEEEECCCCCEEEEECCCCCCCEEECH
ELATLAEKNEYIHSGRIPALTAVKANNFPTIDAFFQSGRDVFSFATGVVPPQMVEILNRN
HHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHCCCHHHHHHHCCCCHHHHHHHCCC
DLHDKVDYVICHQANLRIIEKISETINIPMEKFVTNVEQYGNTSSAGIPMALAQLQEKDP
CCHHHHCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
NPKTVLMTGFGAGLDYGSMLIRI
CCCEEEEEECCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11133475; 12566566 [H]