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The map label for this gene is yacO [H]

Identifier: 116493236

GI number: 116493236

Start: 1465274

End: 1466032

Strand: Reverse

Name: yacO [H]

Synonym: PEPE_1498

Alternate gene names: 116493236

Gene position: 1466032-1465274 (Counterclockwise)

Preceding gene: 116493237

Following gene: 116493235

Centisome position: 80.01

GC content: 39.92

Gene sequence:

>759_bases
TTGAATAATTCAAATGAAACGCAACAACCAGATTTTGTCATTGGCCGCCATCCAGCAATGGCTAGTTTGCAAAGTGATCA
TTCAATTAACAAGGTTTTTATTCAAGAAGGGCTAAAATCGGATGGAATTGGACAAATTATTGCTAAAGCAAAAAAACAAG
GTCTGGTAATTCAACGAGTTACTAAGTCGAAATTGGATACATTATCGAACGGACAAAATCACCAAGGGGTGGTATTAGCG
GTTGCATCCTTTGAATATGCTGAATTAGATGATATCTTCAAGTTAGCTAAAGCACGCGAAGAGGAACCCTTCATTTTAAT
TTTAGATGGAATTGAAGACCCGCATAACTTAGGTTCAATTTTAAGAACGGCAGATGCAGCAGGCGTTCACGGAGTAATTA
TTCCAAAACGACGGGCAGTTGGTTTAACCAGTACCGTAGCCAAAACTTCTGCGGGAGCAATTGAACGAGTTCCTGTCGTC
CAAGTTAGCAACTTAGTTAACGCGATTAAAGAACTTAAAGAACGTGGACTTTGGATTTTTGGTACTGATATGAAGGGAAC
GGATTATCGCCGCTGGGATGCAAAAGGGGCGGTAGGTTTGATTATCGGTAACGAAGGAAAAGGTATGGCCCGCCTAACTA
AGGATAATGTGGACGAAATGTTAACGATTCCGATGGTTGGTGAAATTCAAAGTTTAAATGCAAGTGTAGCAGCCGGACTT
TTAATTTACCAAGGCTATAATTCAAGACATCAACTTTAA

Upstream 100 bases:

>100_bases
GAGGCAATTGTTGGATATCTGTCATTGACAAATCAAACTGAACGTTTAGCTGAATTTGCTCAATGGTGTATTGAAAAAGT
CGAGGAAGGAAATTTACGTA

Downstream 100 bases:

>100_bases
AAATTAGAAACGAATGATTGGAATGCCAATTATTCGTTTTTTATTTACGAAAAATGCGGTTAGAAAATTTTAACAACCTT
GCTAAGATCGTTTCCATTGA

Product: rRNA methylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MNNSNETQQPDFVIGRHPAMASLQSDHSINKVFIQEGLKSDGIGQIIAKAKKQGLVIQRVTKSKLDTLSNGQNHQGVVLA
VASFEYAELDDIFKLAKAREEEPFILILDGIEDPHNLGSILRTADAAGVHGVIIPKRRAVGLTSTVAKTSAGAIERVPVV
QVSNLVNAIKELKERGLWIFGTDMKGTDYRRWDAKGAVGLIIGNEGKGMARLTKDNVDEMLTIPMVGEIQSLNASVAAGL
LIYQGYNSRHQL

Sequences:

>Translated_252_residues
MNNSNETQQPDFVIGRHPAMASLQSDHSINKVFIQEGLKSDGIGQIIAKAKKQGLVIQRVTKSKLDTLSNGQNHQGVVLA
VASFEYAELDDIFKLAKAREEEPFILILDGIEDPHNLGSILRTADAAGVHGVIIPKRRAVGLTSTVAKTSAGAIERVPVV
QVSNLVNAIKELKERGLWIFGTDMKGTDYRRWDAKGAVGLIIGNEGKGMARLTKDNVDEMLTIPMVGEIQSLNASVAAGL
LIYQGYNSRHQL
>Mature_252_residues
MNNSNETQQPDFVIGRHPAMASLQSDHSINKVFIQEGLKSDGIGQIIAKAKKQGLVIQRVTKSKLDTLSNGQNHQGVVLA
VASFEYAELDDIFKLAKAREEEPFILILDGIEDPHNLGSILRTADAAGVHGVIIPKRRAVGLTSTVAKTSAGAIERVPVV
QVSNLVNAIKELKERGLWIFGTDMKGTDYRRWDAKGAVGLIIGNEGKGMARLTKDNVDEMLTIPMVGEIQSLNASVAAGL
LIYQGYNSRHQL

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=266, Percent_Identity=27.4436090225564, Blast_Score=104, Evalue=9e-23,
Organism=Escherichia coli, GI1790623, Length=242, Percent_Identity=39.2561983471074, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1790083, Length=168, Percent_Identity=30.952380952381, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788935, Length=189, Percent_Identity=25.9259259259259, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17555908, Length=256, Percent_Identity=25, Blast_Score=80, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6324775, Length=165, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27335; Mature: 27335

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNSNETQQPDFVIGRHPAMASLQSDHSINKVFIQEGLKSDGIGQIIAKAKKQGLVIQRV
CCCCCCCCCCCEEEECCCHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHH
TKSKLDTLSNGQNHQGVVLAVASFEYAELDDIFKLAKAREEEPFILILDGIEDPHNLGSI
HHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH
LRTADAAGVHGVIIPKRRAVGLTSTVAKTSAGAIERVPVVQVSNLVNAIKELKERGLWIF
HHHHCCCCCCEEEECCCCCCCCHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHCCCEEE
GTDMKGTDYRRWDAKGAVGLIIGNEGKGMARLTKDNVDEMLTIPMVGEIQSLNASVAAGL
ECCCCCCCCEEECCCCCEEEEECCCCCCCCCCCCCCCCCEEECCCCCCHHHCCHHHHHCE
LIYQGYNSRHQL
EEECCCCCCCCC
>Mature Secondary Structure
MNNSNETQQPDFVIGRHPAMASLQSDHSINKVFIQEGLKSDGIGQIIAKAKKQGLVIQRV
CCCCCCCCCCCEEEECCCHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHH
TKSKLDTLSNGQNHQGVVLAVASFEYAELDDIFKLAKAREEEPFILILDGIEDPHNLGSI
HHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH
LRTADAAGVHGVIIPKRRAVGLTSTVAKTSAGAIERVPVVQVSNLVNAIKELKERGLWIF
HHHHCCCCCCEEEECCCCCCCCHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHCCCEEE
GTDMKGTDYRRWDAKGAVGLIIGNEGKGMARLTKDNVDEMLTIPMVGEIQSLNASVAAGL
ECCCCCCCCEEECCCCCEEEEECCCCCCCCCCCCCCCCCEEECCCCCCHHHCCHHHHHCE
LIYQGYNSRHQL
EEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]