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The map label for this gene is tadA [H]

Identifier: 116493223

GI number: 116493223

Start: 1456157

End: 1456642

Strand: Reverse

Name: tadA [H]

Synonym: PEPE_1485

Alternate gene names: 116493223

Gene position: 1456642-1456157 (Counterclockwise)

Preceding gene: 116493224

Following gene: 116493222

Centisome position: 79.49

GC content: 39.3

Gene sequence:

>486_bases
ATGAATAAGTTAACAGAGCATGAAATTAATTTTTATATGAATGAAGCAATTAAAGAGGCCCAATTCGCCAAAATGATTGA
TGAGGTCCCCATTGGAGCAGTGGTTGTTCATGATGGTAAAATTATCGGTCGTGGTCATAACTTAAGAGAACACTCACAGG
ATTCAACCACTCATGCGGAAGTCTTAGCTATTACGGAAGCTTGCGCTTATTTAAAAAGCTGGCGGCTGTGGGATTGTCAG
CTTTTTGTGACCATTGAACCATGCTTAATGTGTAGTGGAACCATCATCAATTCACAATTACCTCAAGTATTTTTTGGTGC
TCGAGATCCTAAAGCAGGAGCGGTTCGAAGCCTGTATACCGTACTCGAAGATACGCGTTTAAACCATCAAGTGACGGTTC
ATGAAGGGATTGAAGCTGACCGAGCATCGATGTTAATGAAGACGTTTTTTAAAGAAATTCGAAAAAGAAGAAAAAAAACT
AAGTAA

Upstream 100 bases:

>100_bases
AAACAGGGGGCGCCCTCAGCTAAAAAATTAATGCAAGAAACCTTTGGGAATGTCGAAGTCCTAAAAAAGAATAAAGGATA
TTATATTTTAAGAAGTGCAC

Downstream 100 bases:

>100_bases
AATAGTGGAAATTTTTTTAAAATTCGAGTATCATAGTTATTGCCGTAAGGCCTTGAGGCAAGGTTGGACTTACGAATTGT
GTCAGGTCCGGAAGGAAGCA

Product: tRNA-adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MNKLTEHEINFYMNEAIKEAQFAKMIDEVPIGAVVVHDGKIIGRGHNLREHSQDSTTHAEVLAITEACAYLKSWRLWDCQ
LFVTIEPCLMCSGTIINSQLPQVFFGARDPKAGAVRSLYTVLEDTRLNHQVTVHEGIEADRASMLMKTFFKEIRKRRKKT
K

Sequences:

>Translated_161_residues
MNKLTEHEINFYMNEAIKEAQFAKMIDEVPIGAVVVHDGKIIGRGHNLREHSQDSTTHAEVLAITEACAYLKSWRLWDCQ
LFVTIEPCLMCSGTIINSQLPQVFFGARDPKAGAVRSLYTVLEDTRLNHQVTVHEGIEADRASMLMKTFFKEIRKRRKKT
K
>Mature_161_residues
MNKLTEHEINFYMNEAIKEAQFAKMIDEVPIGAVVVHDGKIIGRGHNLREHSQDSTTHAEVLAITEACAYLKSWRLWDCQ
LFVTIEPCLMCSGTIINSQLPQVFFGARDPKAGAVRSLYTVLEDTRLNHQVTVHEGIEADRASMLMKTFFKEIRKRRKKT
K

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=168, Percent_Identity=27.3809523809524, Blast_Score=77, Evalue=9e-15,
Organism=Escherichia coli, GI145693172, Length=151, Percent_Identity=41.7218543046358, Blast_Score=129, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17541138, Length=171, Percent_Identity=33.9181286549708, Blast_Score=94, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17554608, Length=105, Percent_Identity=39.0476190476191, Blast_Score=83, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17555996, Length=137, Percent_Identity=31.3868613138686, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325319, Length=143, Percent_Identity=31.4685314685315, Blast_Score=70, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322425, Length=163, Percent_Identity=28.2208588957055, Blast_Score=66, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21355527, Length=147, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 18405; Mature: 18405

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLTEHEINFYMNEAIKEAQFAKMIDEVPIGAVVVHDGKIIGRGHNLREHSQDSTTHAE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEECCCCCHHCCCCCCHHHH
VLAITEACAYLKSWRLWDCQLFVTIEPCLMCSGTIINSQLPQVFFGARDPKAGAVRSLYT
HHHHHHHHHHHHCCCEEEEEEEEEECHHHHHCCCCCCCCCCHHHCCCCCCCCHHHHHHHH
VLEDTRLNHQVTVHEGIEADRASMLMKTFFKEIRKRRKKTK
HHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKLTEHEINFYMNEAIKEAQFAKMIDEVPIGAVVVHDGKIIGRGHNLREHSQDSTTHAE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEECCCCCHHCCCCCCHHHH
VLAITEACAYLKSWRLWDCQLFVTIEPCLMCSGTIINSQLPQVFFGARDPKAGAVRSLYT
HHHHHHHHHHHHCCCEEEEEEEEEECHHHHHCCCCCCCCCCHHHCCCCCCCCHHHHHHHH
VLEDTRLNHQVTVHEGIEADRASMLMKTFFKEIRKRRKKTK
HHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]