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The map label for this gene is 116493186

Identifier: 116493186

GI number: 116493186

Start: 1421394

End: 1422956

Strand: Reverse

Name: 116493186

Synonym: PEPE_1448

Alternate gene names: NA

Gene position: 1422956-1421394 (Counterclockwise)

Preceding gene: 116493187

Following gene: 116493185

Centisome position: 77.66

GC content: 39.22

Gene sequence:

>1563_bases
ATGGCAACGATTTTGATCGTCGTTTTGCTATTGGCTTCCATTGGAGTAGGGTATGGATTGCGAGCCAAAAAGCATAGTGA
AACATTAGCGCAAGCCCGCAAAGCGGCAGAAAAAATTATTGAACATGAACGGCAAAAAACTAAAGCCGAAGTGGCTGAAT
ATGAAAAAAATAGTGTTCAAGAAACTCAACAATATCAAGAGACCATTGACCAAGAACTCGCAGATGATCTACATGATAAT
CAACGTAAAGAGGCGTGGATTGAACAAAGAATGAACTTATTGAACCAAAAAAAGATTGTGTTAACTAATCGAGCAGATGC
ATTAGCTAAAAAAAGACAAAGTCTATTACAAGAACGTGACAACGTACGGACAACTTTAGGCGAAGCTAAACAACTAATTA
CTGATCGATGGAATAAACTTCAGGAAGTTGCTGATTTGGAAGAGCAAGCAGCTTCAAAGTTGGTTTTGAAAGAAACTAAA
CAAGATGCAATTCGTTCTAAAGATGAGTTTGTTAATAACGCTCAAACCGAATTAGAAAGCTCCTGCGAGCGTGAAGCTGA
GGATTTGATAGCTTTAGCCATGGAACATAGTGATGTTCCAAGAGGTCAAGCCGAAAATCACCGCAGTTTTATTGCAGAAA
ATGCTGAATATCTTGGTAAACTGATTGGAAATTCGGGTCAGAATGTACGAGCAATTGAAGCATTAACTGGTGTAGATATT
GTGATTGATGATCAAGAAAAAGAGGTCATTCTTAACGGATATGACCCAGTTCGTCGAGCAGTGGCCATGGAAACCATGGA
AATGATTAAAACTGAGAAACGAGTTGTTCCAGATACAATCGAACGGTTGGTTAATAAGGCTAATAAAGTAATTGACCAGC
GTATTCGCCAGTATGGGGAAGACGCGGTTCGAGAATTGAAATTAAAATATGTTGCGCCGGATTTAATCAAATTTATTGGT
CGAATGCATTACCGGACGAGTTATGGACAAAATATTTTAGAACATTCTATTGAAACTGCTAAGCTAGCAGGTATTTTTGC
TGTTGAGTTAGGTGAAGACGCTACTTTAGCACGACGTGCAGGCTTACTACATGATATCGGTAAATCTATTGATCGCGATA
TTGAAGCGACTCATGTGGAATTGGGTGTGGAATTGACCACCAAATATCGAGAGAGTCCAGTGATAGTGAATACTATTGCT
TCTCACCATGGGGATGTTGAAGCTCGATATGTAATTGCTAATTTGGTTGAGGCAGCGGATGCCATTTCTGGAGCTCGTCA
AGGTGCTAGAAGTGAATCAGTGGCTGACTATATCCAAAGAATTAAGAGCTTAGAAGAGATTGCTAACAAACATCCAGAAG
TCAAGGAAAGTTATGCTATCCAAGCTGGTCGTGAACTTCGAGTAATTGTTCAACCTAAAGAGACAGATGATAAGACGATT
CATAGTTTAGCTACTAACGTAAAGAATCAGATTGAAGAGGATGTTACTTATCCTGGTCAGGTGAAGGTAACGGTTGTTAG
AAAGTTAGAGATTGTAGAATACGTGGAGAAAAAACAAGCATGA

Upstream 100 bases:

>100_bases
TTAACGTAAGTTTCTTCTAAGAAGCTCTTTTTTTGTACCAACTTTTTGAATATATTTTTATGATATAATTAACTTCGACT
AAAAAGAAAGGGGCGACGCG

Downstream 100 bases:

>100_bases
GTGAAGACAACACCGCACAGTTAGAAAAAATCGATAGTTTTGTTAAAGAGAAGCTTCAAGATGACTTAACCGGGCATGAT
TATGCTCATATTCAACGAGT

Product: HD superfamily hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MATILIVVLLLASIGVGYGLRAKKHSETLAQARKAAEKIIEHERQKTKAEVAEYEKNSVQETQQYQETIDQELADDLHDN
QRKEAWIEQRMNLLNQKKIVLTNRADALAKKRQSLLQERDNVRTTLGEAKQLITDRWNKLQEVADLEEQAASKLVLKETK
QDAIRSKDEFVNNAQTELESSCEREAEDLIALAMEHSDVPRGQAENHRSFIAENAEYLGKLIGNSGQNVRAIEALTGVDI
VIDDQEKEVILNGYDPVRRAVAMETMEMIKTEKRVVPDTIERLVNKANKVIDQRIRQYGEDAVRELKLKYVAPDLIKFIG
RMHYRTSYGQNILEHSIETAKLAGIFAVELGEDATLARRAGLLHDIGKSIDRDIEATHVELGVELTTKYRESPVIVNTIA
SHHGDVEARYVIANLVEAADAISGARQGARSESVADYIQRIKSLEEIANKHPEVKESYAIQAGRELRVIVQPKETDDKTI
HSLATNVKNQIEEDVTYPGQVKVTVVRKLEIVEYVEKKQA

Sequences:

>Translated_520_residues
MATILIVVLLLASIGVGYGLRAKKHSETLAQARKAAEKIIEHERQKTKAEVAEYEKNSVQETQQYQETIDQELADDLHDN
QRKEAWIEQRMNLLNQKKIVLTNRADALAKKRQSLLQERDNVRTTLGEAKQLITDRWNKLQEVADLEEQAASKLVLKETK
QDAIRSKDEFVNNAQTELESSCEREAEDLIALAMEHSDVPRGQAENHRSFIAENAEYLGKLIGNSGQNVRAIEALTGVDI
VIDDQEKEVILNGYDPVRRAVAMETMEMIKTEKRVVPDTIERLVNKANKVIDQRIRQYGEDAVRELKLKYVAPDLIKFIG
RMHYRTSYGQNILEHSIETAKLAGIFAVELGEDATLARRAGLLHDIGKSIDRDIEATHVELGVELTTKYRESPVIVNTIA
SHHGDVEARYVIANLVEAADAISGARQGARSESVADYIQRIKSLEEIANKHPEVKESYAIQAGRELRVIVQPKETDDKTI
HSLATNVKNQIEEDVTYPGQVKVTVVRKLEIVEYVEKKQA
>Mature_519_residues
ATILIVVLLLASIGVGYGLRAKKHSETLAQARKAAEKIIEHERQKTKAEVAEYEKNSVQETQQYQETIDQELADDLHDNQ
RKEAWIEQRMNLLNQKKIVLTNRADALAKKRQSLLQERDNVRTTLGEAKQLITDRWNKLQEVADLEEQAASKLVLKETKQ
DAIRSKDEFVNNAQTELESSCEREAEDLIALAMEHSDVPRGQAENHRSFIAENAEYLGKLIGNSGQNVRAIEALTGVDIV
IDDQEKEVILNGYDPVRRAVAMETMEMIKTEKRVVPDTIERLVNKANKVIDQRIRQYGEDAVRELKLKYVAPDLIKFIGR
MHYRTSYGQNILEHSIETAKLAGIFAVELGEDATLARRAGLLHDIGKSIDRDIEATHVELGVELTTKYRESPVIVNTIAS
HHGDVEARYVIANLVEAADAISGARQGARSESVADYIQRIKSLEEIANKHPEVKESYAIQAGRELRVIVQPKETDDKTIH
SLATNVKNQIEEDVTYPGQVKVTVVRKLEIVEYVEKKQA

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CNPD2_PEDPA (Q03E93)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804921.1
- ProteinModelPortal:   Q03E93
- STRING:   Q03E93
- GeneID:   4417271
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1448
- NMPDR:   fig|278197.10.peg.1274
- eggNOG:   COG1418
- HOGENOM:   HBG734610
- OMA:   ESYAIQA
- BioCyc:   PPEN278197:PEPE_1448-MONOMER
- GO:   GO:0016020
- HAMAP:   MF_00335
- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675
- SMART:   SM00471
- SMART:   SM00322
- TIGRFAMs:   TIGR00277
- TIGRFAMs:   TIGR03319

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1

EC number: =3.1.4.16

Molecular weight: Translated: 58704; Mature: 58573

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATILIVVLLLASIGVGYGLRAKKHSETLAQARKAAEKIIEHERQKTKAEVAEYEKNSVQ
CHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETQQYQETIDQELADDLHDNQRKEAWIEQRMNLLNQKKIVLTNRADALAKKRQSLLQERD
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHH
NVRTTLGEAKQLITDRWNKLQEVADLEEQAASKLVLKETKQDAIRSKDEFVNNAQTELES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SCEREAEDLIALAMEHSDVPRGQAENHRSFIAENAEYLGKLIGNSGQNVRAIEALTGVDI
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCEE
VIDDQEKEVILNGYDPVRRAVAMETMEMIKTEKRVVPDTIERLVNKANKVIDQRIRQYGE
EEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
DAVRELKLKYVAPDLIKFIGRMHYRTSYGQNILEHSIETAKLAGIFAVELGEDATLARRA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHH
GLLHDIGKSIDRDIEATHVELGVELTTKYRESPVIVNTIASHHGDVEARYVIANLVEAAD
HHHHHHHHHHCCCCHHHHHHHCHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHH
AISGARQGARSESVADYIQRIKSLEEIANKHPEVKESYAIQAGRELRVIVQPKETDDKTI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCCHHHH
HSLATNVKNQIEEDVTYPGQVKVTVVRKLEIVEYVEKKQA
HHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATILIVVLLLASIGVGYGLRAKKHSETLAQARKAAEKIIEHERQKTKAEVAEYEKNSVQ
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETQQYQETIDQELADDLHDNQRKEAWIEQRMNLLNQKKIVLTNRADALAKKRQSLLQERD
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHH
NVRTTLGEAKQLITDRWNKLQEVADLEEQAASKLVLKETKQDAIRSKDEFVNNAQTELES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SCEREAEDLIALAMEHSDVPRGQAENHRSFIAENAEYLGKLIGNSGQNVRAIEALTGVDI
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCEE
VIDDQEKEVILNGYDPVRRAVAMETMEMIKTEKRVVPDTIERLVNKANKVIDQRIRQYGE
EEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
DAVRELKLKYVAPDLIKFIGRMHYRTSYGQNILEHSIETAKLAGIFAVELGEDATLARRA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHH
GLLHDIGKSIDRDIEATHVELGVELTTKYRESPVIVNTIASHHGDVEARYVIANLVEAAD
HHHHHHHHHHCCCCHHHHHHHCHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHH
AISGARQGARSESVADYIQRIKSLEEIANKHPEVKESYAIQAGRELRVIVQPKETDDKTI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCCHHHH
HSLATNVKNQIEEDVTYPGQVKVTVVRKLEIVEYVEKKQA
HHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA