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The map label for this gene is gntK [H]

Identifier: 116493107

GI number: 116493107

Start: 1347533

End: 1349095

Strand: Reverse

Name: gntK [H]

Synonym: PEPE_1361

Alternate gene names: 116493107

Gene position: 1349095-1347533 (Counterclockwise)

Preceding gene: 116493108

Following gene: 116493106

Centisome position: 73.63

GC content: 39.48

Gene sequence:

>1563_bases
ATGGATTATATGATTGGTGTTGATCTTGGCACTACTAGTACAAAAGTAGTTTTATTTGATATGAAGGGAAATTCAATTGC
CTATGCAAACAATCCTTATCCTTTATATCAGGATAGTCCAGATATGGCCGAGGAAGATCCAGCCGAAATTTTTGAAGCAG
TTATTAATGGATTAACTGAAGTGATGCGTAAGGGAAATGTTAAGAATGGTGAATTAAAGGGAGTATCATTCTCAAGTGCG
ATGCATAGTTTGATTTTGATGGATAAAGATAATCATCCATTAACTAGAGTTATAACTTGGGCAGATAACCGTTCGAGCAA
GTATGCTGAAGAATTAAAGGACAATGGACTTGGCCAACAATTATACGCCCATACTGGTGTACCCACTCATCCAATGTCAC
CATTAGTTAAATTGATTTGGTTAAAGAATGAACAACCAGAAATTTTTAAAAAGGCGACTCATTTTATTGGTATTAAGGAT
TATGTTTTATTTCGATTATATGGAAAGTATGTTCAGGACTACTCTCTTGCTAACGCGACTGGACTATTTAACATTTTCAC
GATGGATTGGGATGAACAAGCCCTTGAAATTACGGGTGTAACGCGAGACCAGCTTCCAGAATTAGTTTCCCCTGAATATC
AATTAACGGGGTTAGCTAAATCGTATGCGGAGGTGACTGGGATTCCGGAAGATACTCCGTTCATCATGGGAGCTAGTGAT
GGTACCCTTAGTAATCTAGGGGTTAATGCAATTGAACCAGGAGTTTTGGCGGTAACAATTGGAACTTCTGGAGCAGTACG
CGTGGTTGTGGATAAGCCAGTTGTTGATCCACGGGGTCGATTATTCACATATTACTTAGATGATGGTAAGTGGGTAGTAG
GTGGACCGGTCAATAATGGTGGAATTGTATTTCGCTGGGTTCGCGATCAATTATTCTCTCCTGAAAAAATTACGGCTGAA
CAAATGCAAGTCAATTCTTATGAAATTTTAACCGACATTGCTTCTAAGATTCCAGCTGGCGCAGATGGACTATTATTTCA
CCCATATTTAGGCGGAGAAAGAGCGCCGATTTGGGATGCAAACGCACGTGGAAGTTTCTTCGGATTAACGCGTCAACATA
CTCGTGCACACATGGTTAGAGCAGCTTTGGAAGGCATTGTATATAACCTTTACATGGTAATGCTAATGATTGAAGGAGTA
GCCGGTAAACCGAAATCAATTCAAGCCACCGGTGGATTTGCTAGGAGCGCACTTTGGCGTCAAATGTTAGCTGACATTTT
TGAACAAGATGTTAATATTCCAGAAAGTTTTGAAAGCTCAGCGCTGGGGGCCGTGGTGATAGGGATGAAGAGTTTGGGAA
TTGTCGACGATTTGAGCGTTGTTAAGGATATGGTTGGGGTAACAAATACACATAAACCCAATCAAGAGAATTTTGCTTCC
TATCGAGAATTGCTACCAATTTGGATTAGATTAACAGATGAATTATCTGGAGAATACGATAGTATTGCAAAATTTCAAAG
AAATCATCCTAATGAACATGCAAAAATAGCTGAAGAAGATTAA

Upstream 100 bases:

>100_bases
CTGAAGAAGATGATACGATGACAGGAAAAGTAGTATCTGCCTTAAGAAATGGTTTTGGCGGACATAAAGTTGATCATAAA
GAATAGTTGAGGTACAGAAT

Downstream 100 bases:

>100_bases
AGAGACGATCAACGGTCTTTTTAATTTAATAGCAAAAAGAAAGCGGTTACTTAGATGGGGGCGTGTTATTTATGGAAATT
ATGGTCTTAGTTATTGGAAT

Product: gluconate kinase

Products: NA

Alternate protein names: Gluconate kinase [H]

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MDYMIGVDLGTTSTKVVLFDMKGNSIAYANNPYPLYQDSPDMAEEDPAEIFEAVINGLTEVMRKGNVKNGELKGVSFSSA
MHSLILMDKDNHPLTRVITWADNRSSKYAEELKDNGLGQQLYAHTGVPTHPMSPLVKLIWLKNEQPEIFKKATHFIGIKD
YVLFRLYGKYVQDYSLANATGLFNIFTMDWDEQALEITGVTRDQLPELVSPEYQLTGLAKSYAEVTGIPEDTPFIMGASD
GTLSNLGVNAIEPGVLAVTIGTSGAVRVVVDKPVVDPRGRLFTYYLDDGKWVVGGPVNNGGIVFRWVRDQLFSPEKITAE
QMQVNSYEILTDIASKIPAGADGLLFHPYLGGERAPIWDANARGSFFGLTRQHTRAHMVRAALEGIVYNLYMVMLMIEGV
AGKPKSIQATGGFARSALWRQMLADIFEQDVNIPESFESSALGAVVIGMKSLGIVDDLSVVKDMVGVTNTHKPNQENFAS
YRELLPIWIRLTDELSGEYDSIAKFQRNHPNEHAKIAEED

Sequences:

>Translated_520_residues
MDYMIGVDLGTTSTKVVLFDMKGNSIAYANNPYPLYQDSPDMAEEDPAEIFEAVINGLTEVMRKGNVKNGELKGVSFSSA
MHSLILMDKDNHPLTRVITWADNRSSKYAEELKDNGLGQQLYAHTGVPTHPMSPLVKLIWLKNEQPEIFKKATHFIGIKD
YVLFRLYGKYVQDYSLANATGLFNIFTMDWDEQALEITGVTRDQLPELVSPEYQLTGLAKSYAEVTGIPEDTPFIMGASD
GTLSNLGVNAIEPGVLAVTIGTSGAVRVVVDKPVVDPRGRLFTYYLDDGKWVVGGPVNNGGIVFRWVRDQLFSPEKITAE
QMQVNSYEILTDIASKIPAGADGLLFHPYLGGERAPIWDANARGSFFGLTRQHTRAHMVRAALEGIVYNLYMVMLMIEGV
AGKPKSIQATGGFARSALWRQMLADIFEQDVNIPESFESSALGAVVIGMKSLGIVDDLSVVKDMVGVTNTHKPNQENFAS
YRELLPIWIRLTDELSGEYDSIAKFQRNHPNEHAKIAEED
>Mature_520_residues
MDYMIGVDLGTTSTKVVLFDMKGNSIAYANNPYPLYQDSPDMAEEDPAEIFEAVINGLTEVMRKGNVKNGELKGVSFSSA
MHSLILMDKDNHPLTRVITWADNRSSKYAEELKDNGLGQQLYAHTGVPTHPMSPLVKLIWLKNEQPEIFKKATHFIGIKD
YVLFRLYGKYVQDYSLANATGLFNIFTMDWDEQALEITGVTRDQLPELVSPEYQLTGLAKSYAEVTGIPEDTPFIMGASD
GTLSNLGVNAIEPGVLAVTIGTSGAVRVVVDKPVVDPRGRLFTYYLDDGKWVVGGPVNNGGIVFRWVRDQLFSPEKITAE
QMQVNSYEILTDIASKIPAGADGLLFHPYLGGERAPIWDANARGSFFGLTRQHTRAHMVRAALEGIVYNLYMVMLMIEGV
AGKPKSIQATGGFARSALWRQMLADIFEQDVNIPESFESSALGAVVIGMKSLGIVDDLSVVKDMVGVTNTHKPNQENFAS
YRELLPIWIRLTDELSGEYDSIAKFQRNHPNEHAKIAEED

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=460, Percent_Identity=26.7391304347826, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI189409120, Length=459, Percent_Identity=26.5795206971678, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI4504007, Length=459, Percent_Identity=26.5795206971678, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI41393575, Length=449, Percent_Identity=26.0579064587973, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI88196792, Length=525, Percent_Identity=20.7619047619048, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI164663828, Length=554, Percent_Identity=24.0072202166065, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI164663830, Length=578, Percent_Identity=23.5294117647059, Blast_Score=84, Evalue=5e-16,
Organism=Escherichia coli, GI1789987, Length=494, Percent_Identity=26.7206477732794, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1787789, Length=503, Percent_Identity=26.6401590457256, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1790361, Length=492, Percent_Identity=25, Blast_Score=158, Evalue=9e-40,
Organism=Escherichia coli, GI1790005, Length=504, Percent_Identity=24.6031746031746, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1789168, Length=467, Percent_Identity=23.5546038543897, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1789138, Length=501, Percent_Identity=22.5548902195609, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17535599, Length=464, Percent_Identity=25, Blast_Score=125, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6321755, Length=430, Percent_Identity=23.953488372093, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6320314, Length=526, Percent_Identity=22.4334600760456, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI17864214, Length=477, Percent_Identity=25.3668763102725, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24656367, Length=529, Percent_Identity=22.4952741020794, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24654573, Length=404, Percent_Identity=25.990099009901, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21357867, Length=541, Percent_Identity=21.2569316081331, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24655555, Length=430, Percent_Identity=23.4883720930233, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24655560, Length=430, Percent_Identity=23.4883720930233, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24655570, Length=430, Percent_Identity=23.4883720930233, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24655574, Length=430, Percent_Identity=23.4883720930233, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24655565, Length=430, Percent_Identity=23.4883720930233, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24656372, Length=346, Percent_Identity=25.4335260115607, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24652871, Length=439, Percent_Identity=22.0956719817768, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19922058, Length=439, Percent_Identity=22.0956719817768, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI45552909, Length=240, Percent_Identity=25.4166666666667, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006002 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 57556; Mature: 57556

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYMIGVDLGTTSTKVVLFDMKGNSIAYANNPYPLYQDSPDMAEEDPAEIFEAVINGLTE
CCEEEEEECCCCCEEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VMRKGNVKNGELKGVSFSSAMHSLILMDKDNHPLTRVITWADNRSSKYAEELKDNGLGQQ
HHHCCCCCCCCCCCEEHHHHHCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHCCCCCH
LYAHTGVPTHPMSPLVKLIWLKNEQPEIFKKATHFIGIKDYVLFRLYGKYVQDYSLANAT
HHHCCCCCCCCHHHHHEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCC
GLFNIFTMDWDEQALEITGVTRDQLPELVSPEYQLTGLAKSYAEVTGIPEDTPFIMGASD
CEEEEEEECCCCCEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEECCC
GTLSNLGVNAIEPGVLAVTIGTSGAVRVVVDKPVVDPRGRLFTYYLDDGKWVVGGPVNNG
CCHHHCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCEEEEEEECCCEEECCCCCCC
GIVFRWVRDQLFSPEKITAEQMQVNSYEILTDIASKIPAGADGLLFHPYLGGERAPIWDA
CEEEEEEHHHCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCC
NARGSFFGLTRQHTRAHMVRAALEGIVYNLYMVMLMIEGVAGKPKSIQATGGFARSALWR
CCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHH
QMLADIFEQDVNIPESFESSALGAVVIGMKSLGIVDDLSVVKDMVGVTNTHKPNQENFAS
HHHHHHHHHCCCCCCHHHCCCCCEEEECHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHH
YRELLPIWIRLTDELSGEYDSIAKFQRNHPNEHAKIAEED
HHHHHHEEEEEEHHHCCCHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MDYMIGVDLGTTSTKVVLFDMKGNSIAYANNPYPLYQDSPDMAEEDPAEIFEAVINGLTE
CCEEEEEECCCCCEEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VMRKGNVKNGELKGVSFSSAMHSLILMDKDNHPLTRVITWADNRSSKYAEELKDNGLGQQ
HHHCCCCCCCCCCCEEHHHHHCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHCCCCCH
LYAHTGVPTHPMSPLVKLIWLKNEQPEIFKKATHFIGIKDYVLFRLYGKYVQDYSLANAT
HHHCCCCCCCCHHHHHEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCC
GLFNIFTMDWDEQALEITGVTRDQLPELVSPEYQLTGLAKSYAEVTGIPEDTPFIMGASD
CEEEEEEECCCCCEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEECCC
GTLSNLGVNAIEPGVLAVTIGTSGAVRVVVDKPVVDPRGRLFTYYLDDGKWVVGGPVNNG
CCHHHCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCEEEEEEECCCEEECCCCCCC
GIVFRWVRDQLFSPEKITAEQMQVNSYEILTDIASKIPAGADGLLFHPYLGGERAPIWDA
CEEEEEEHHHCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCC
NARGSFFGLTRQHTRAHMVRAALEGIVYNLYMVMLMIEGVAGKPKSIQATGGFARSALWR
CCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHH
QMLADIFEQDVNIPESFESSALGAVVIGMKSLGIVDDLSVVKDMVGVTNTHKPNQENFAS
HHHHHHHHHCCCCCCHHHCCCCCEEEECHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHH
YRELLPIWIRLTDELSGEYDSIAKFQRNHPNEHAKIAEED
HHHHHHEEEEEEHHHCCCHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8535972 [H]