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The map label for this gene is pgi

Identifier: 116493096

GI number: 116493096

Start: 1335739

End: 1337088

Strand: Reverse

Name: pgi

Synonym: PEPE_1350

Alternate gene names: 116493096

Gene position: 1337088-1335739 (Counterclockwise)

Preceding gene: 116493097

Following gene: 116493095

Centisome position: 72.97

GC content: 40.3

Gene sequence:

>1350_bases
ATGGCACATATTTCATTTGACAGTTCTAATGTTGCAGATTTTGTACATGAAAACGAACTTGCAGAAATCCAACCACTTGT
TACAGCTGCTGATCAGATTTTACGTGATGGCTCTGGCGCCGGTAGTGATTTCCGTGGATGGATCGATTTACCATCAAATT
ATGATAAGGACGAATTTGCCCGTATCAAGAAAGCCGCTGATAAGATCCGCAACGACTCAGAAGTATTCGTTGCTATCGGT
ATTGGTGGTTCATATTTGGGTGCTCGTGCAGCCATTGATTTCTTGAACAACACTTTCTACAATCTTCTTACTAAAGAACA
ACGTAATGGTGCTCCTCAAGTAATCTTCGCTGGTAACTCAATTAGTTCAACATATCTTGCAGACGTATTGAACTTGATCG
GTGACCGTGACTTCTCAATTAACGTAATTTCTAAGTCAGGTACAACTACAGAACCAGCTATTGCATTCCGTGTTCTTAAA
GAAAAACTAATCAAGAAGTACGGTGAAGAAGAAGCTAAGAAACGTATTTATGCAACAACTGACCGTGCTAAAGGTGCCCT
AAAGACAGAAGCTGATGCAGAAAACTATGAAGAATTCGTAGTTCCTGATGACATTGGTGGTCGTTTCTCTGTTCTTTCAG
CTGTTGGTTTATTACCAATCGCAGTTGCTGGTGGTGATATTGACCAATTGATGAAGGGTGCTGAAGATGCAAGCAACGAA
TACAAGGATGCTGATGTTACAAAGAACGAAGCATACAAGTACGCTGCTTTACGTAACATCCTTTACCGTAAGGGCTACAC
AACAGAACTTCTTGAAAACTACGAACCAACACTTCAATACTTCGGCGAATGGTGGAAGCAATTGATGGGTGAATCAGAAG
GTAAAGATCAAAAAGGTATCTACCCATCTTCTGCTAACTTCTCAACTGACTTACATTCACTAGGACAATACATCCAAGAA
GGTCGTCGCAATTTGATGGAAACGGTTATCAATGTTGAAAAGCCTAACCATGACATCGACATTCCTAAGGCTGACCAAGA
CCTTGATGGATTACGTTATCTTGAAGGTCGCACAATGGACGAAGTTAACAAGAAAGCTTATCAAGGTGTAACTCTTGCTC
ATAACGACGGTGGTGTTCCAGTTATGACAGTTAACATTCCTGATCAAACAGCTTACACATTAGGCTACATGATTTACTTC
TTCGAAGCAGCTGTTGCTGTATCTGGTTACTTGAACGGAATTAATCCATTCAATCAACCAGGTGTTGAAGCATACAAGTC
AAATATGTTTGCATTACTTGGTAAACCAGGTTATGAAGATAAGACAGCTGAATTAAACGCTCGTCTATAA

Upstream 100 bases:

>100_bases
TAGTAAATATTAGGTTAAATCGGATAGGCTTAACCAAATTAAGTAATTTTATTGTATAATGGTACAGATAAAGAATTTTA
AACAAAAGGGGTAGTTATTA

Downstream 100 bases:

>100_bases
AAAACTGAAGTACTACTCAGAAGCTATCACATTTGTGATAGCTTTTTTTATTGAAAATAATTTCCAAACTACAAAAGAAA
TCGTTTTCTAGGTAAGGTAT

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MAHISFDSSNVADFVHENELAEIQPLVTAADQILRDGSGAGSDFRGWIDLPSNYDKDEFARIKKAADKIRNDSEVFVAIG
IGGSYLGARAAIDFLNNTFYNLLTKEQRNGAPQVIFAGNSISSTYLADVLNLIGDRDFSINVISKSGTTTEPAIAFRVLK
EKLIKKYGEEEAKKRIYATTDRAKGALKTEADAENYEEFVVPDDIGGRFSVLSAVGLLPIAVAGGDIDQLMKGAEDASNE
YKDADVTKNEAYKYAALRNILYRKGYTTELLENYEPTLQYFGEWWKQLMGESEGKDQKGIYPSSANFSTDLHSLGQYIQE
GRRNLMETVINVEKPNHDIDIPKADQDLDGLRYLEGRTMDEVNKKAYQGVTLAHNDGGVPVMTVNIPDQTAYTLGYMIYF
FEAAVAVSGYLNGINPFNQPGVEAYKSNMFALLGKPGYEDKTAELNARL

Sequences:

>Translated_449_residues
MAHISFDSSNVADFVHENELAEIQPLVTAADQILRDGSGAGSDFRGWIDLPSNYDKDEFARIKKAADKIRNDSEVFVAIG
IGGSYLGARAAIDFLNNTFYNLLTKEQRNGAPQVIFAGNSISSTYLADVLNLIGDRDFSINVISKSGTTTEPAIAFRVLK
EKLIKKYGEEEAKKRIYATTDRAKGALKTEADAENYEEFVVPDDIGGRFSVLSAVGLLPIAVAGGDIDQLMKGAEDASNE
YKDADVTKNEAYKYAALRNILYRKGYTTELLENYEPTLQYFGEWWKQLMGESEGKDQKGIYPSSANFSTDLHSLGQYIQE
GRRNLMETVINVEKPNHDIDIPKADQDLDGLRYLEGRTMDEVNKKAYQGVTLAHNDGGVPVMTVNIPDQTAYTLGYMIYF
FEAAVAVSGYLNGINPFNQPGVEAYKSNMFALLGKPGYEDKTAELNARL
>Mature_448_residues
AHISFDSSNVADFVHENELAEIQPLVTAADQILRDGSGAGSDFRGWIDLPSNYDKDEFARIKKAADKIRNDSEVFVAIGI
GGSYLGARAAIDFLNNTFYNLLTKEQRNGAPQVIFAGNSISSTYLADVLNLIGDRDFSINVISKSGTTTEPAIAFRVLKE
KLIKKYGEEEAKKRIYATTDRAKGALKTEADAENYEEFVVPDDIGGRFSVLSAVGLLPIAVAGGDIDQLMKGAEDASNEY
KDADVTKNEAYKYAALRNILYRKGYTTELLENYEPTLQYFGEWWKQLMGESEGKDQKGIYPSSANFSTDLHSLGQYIQEG
RRNLMETVINVEKPNHDIDIPKADQDLDGLRYLEGRTMDEVNKKAYQGVTLAHNDGGVPVMTVNIPDQTAYTLGYMIYFF
EAAVAVSGYLNGINPFNQPGVEAYKSNMFALLGKPGYEDKTAELNARL

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family

Homologues:

Organism=Saccharomyces cerevisiae, GI6319673, Length=376, Percent_Identity=24.2021276595745, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24651916, Length=381, Percent_Identity=26.509186351706, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24651914, Length=381, Percent_Identity=26.509186351706, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17737445, Length=381, Percent_Identity=26.509186351706, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): G6PI_PEDPA (Q03EI3)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804831.1
- ProteinModelPortal:   Q03EI3
- SMR:   Q03EI3
- STRING:   Q03EI3
- GeneID:   4416965
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1350
- NMPDR:   fig|278197.10.peg.1185
- eggNOG:   COG0166
- HOGENOM:   HBG615843
- OMA:   KACAMSA
- ProtClustDB:   PRK14097
- BioCyc:   PPEN278197:PEPE_1350-MONOMER
- GO:   GO:0005737
- GO:   GO:0006094
- GO:   GO:0006096
- HAMAP:   MF_00473
- InterPro:   IPR001672
- InterPro:   IPR018189
- PANTHER:   PTHR11469
- PRINTS:   PR00662

Pfam domain/function: PF00342 PGI

EC number: =5.3.1.9

Molecular weight: Translated: 49653; Mature: 49522

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1; PS00174 P_GLUCOSE_ISOMERASE_2; PS51463 P_GLUCOSE_ISOMERASE_3

Important sites: ACT_SITE 291-291 ACT_SITE 312-312 ACT_SITE 426-426

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHISFDSSNVADFVHENELAEIQPLVTAADQILRDGSGAGSDFRGWIDLPSNYDKDEFA
CCEECCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHH
RIKKAADKIRNDSEVFVAIGIGGSYLGARAAIDFLNNTFYNLLTKEQRNGAPQVIFAGNS
HHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
ISSTYLADVLNLIGDRDFSINVISKSGTTTEPAIAFRVLKEKLIKKYGEEEAKKRIYATT
CCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHEEEEC
DRAKGALKTEADAENYEEFVVPDDIGGRFSVLSAVGLLPIAVAGGDIDQLMKGAEDASNE
HHHCCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHEECCCCHHHHHHCHHHHCCC
YKDADVTKNEAYKYAALRNILYRKGYTTELLENYEPTLQYFGEWWKQLMGESEGKDQKGI
CCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCC
YPSSANFSTDLHSLGQYIQEGRRNLMETVINVEKPNHDIDIPKADQDLDGLRYLEGRTMD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCHH
EVNKKAYQGVTLAHNDGGVPVMTVNIPDQTAYTLGYMIYFFEAAVAVSGYLNGINPFNQP
HHHHHHHCCCEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GVEAYKSNMFALLGKPGYEDKTAELNARL
CHHHHHCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AHISFDSSNVADFVHENELAEIQPLVTAADQILRDGSGAGSDFRGWIDLPSNYDKDEFA
CEECCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHH
RIKKAADKIRNDSEVFVAIGIGGSYLGARAAIDFLNNTFYNLLTKEQRNGAPQVIFAGNS
HHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
ISSTYLADVLNLIGDRDFSINVISKSGTTTEPAIAFRVLKEKLIKKYGEEEAKKRIYATT
CCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHEEEEC
DRAKGALKTEADAENYEEFVVPDDIGGRFSVLSAVGLLPIAVAGGDIDQLMKGAEDASNE
HHHCCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHEECCCCHHHHHHCHHHHCCC
YKDADVTKNEAYKYAALRNILYRKGYTTELLENYEPTLQYFGEWWKQLMGESEGKDQKGI
CCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCC
YPSSANFSTDLHSLGQYIQEGRRNLMETVINVEKPNHDIDIPKADQDLDGLRYLEGRTMD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCHH
EVNKKAYQGVTLAHNDGGVPVMTVNIPDQTAYTLGYMIYFFEAAVAVSGYLNGINPFNQP
HHHHHHHCCCEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GVEAYKSNMFALLGKPGYEDKTAELNARL
CHHHHHCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA