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The map label for this gene is tdk [H]

Identifier: 116493079

GI number: 116493079

Start: 1320471

End: 1321064

Strand: Reverse

Name: tdk [H]

Synonym: PEPE_1331

Alternate gene names: 116493079

Gene position: 1321064-1320471 (Counterclockwise)

Preceding gene: 116493082

Following gene: 116493078

Centisome position: 72.1

GC content: 35.35

Gene sequence:

>594_bases
ATGGCACAGTTATTTTTTCATTACGGAGCAATGAATAGTGGTAAGTCAATTGAAATTTTAAAAGTGGCTCATAACTATGA
AGAACAAGATAAAAAAGTTATTTTAATGACGAGTGGTATTGATACTAGAACGGCTGTTGGTGAAATTTCCAGCCGGATTG
GGTTGCGCCGAGATGCTCTTCCAATTTTTGATGATACGAATATTTTGGAATTGATTACGCAAGCTAGTGCCCAAGAAGAT
ACTGCTTGTATCTTGATTGATGAAGCTCAATTTTTGAAAAAACATCACATTATAGAACTAGCTAAAGTAGTCGATGACTT
AGGAATTCCAGTCATGACGTTTGGTTTAAAAAATGATTTCAGAAATGAATTGTTTGAAGGAACTAAATACTTACTTTTAT
ATGCCGATAAAATTGTGGAAATGAAGACAATTTGTTGGTTCTGTAAGCACAAAGCGCTAATGAATTTACGCGTTCATGAT
GGTAAACCGGTCTATGATGGTGAGCAAGTTCAAATTGGTGGTAATGAGTCTTATTACCCGGTTTGTCGTCGCCATTATTT
TCACCCACTGACTGAAGAAGAAATGAGGAATTAA

Upstream 100 bases:

>100_bases
TTGATAAAAAAGAAAGTTTCTTATATTAATAAGAGATGAATTTTTATTTTATATCAGCTATACTTAAATTTCGGAGAATA
AAATTAGGAGTGGGGCTAGA

Downstream 100 bases:

>100_bases
TTAAATGGATATTATTGAAAAAGTTCAGGCTGTTGCCGACCGCTATGAAGAATTAAGCGAACTATTAGCTGATCCTGAAG
TTCTAGGAGATTCACAACGT

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MAQLFFHYGAMNSGKSIEILKVAHNYEEQDKKVILMTSGIDTRTAVGEISSRIGLRRDALPIFDDTNILELITQASAQED
TACILIDEAQFLKKHHIIELAKVVDDLGIPVMTFGLKNDFRNELFEGTKYLLLYADKIVEMKTICWFCKHKALMNLRVHD
GKPVYDGEQVQIGGNESYYPVCRRHYFHPLTEEEMRN

Sequences:

>Translated_197_residues
MAQLFFHYGAMNSGKSIEILKVAHNYEEQDKKVILMTSGIDTRTAVGEISSRIGLRRDALPIFDDTNILELITQASAQED
TACILIDEAQFLKKHHIIELAKVVDDLGIPVMTFGLKNDFRNELFEGTKYLLLYADKIVEMKTICWFCKHKALMNLRVHD
GKPVYDGEQVQIGGNESYYPVCRRHYFHPLTEEEMRN
>Mature_196_residues
AQLFFHYGAMNSGKSIEILKVAHNYEEQDKKVILMTSGIDTRTAVGEISSRIGLRRDALPIFDDTNILELITQASAQEDT
ACILIDEAQFLKKHHIIELAKVVDDLGIPVMTFGLKNDFRNELFEGTKYLLLYADKIVEMKTICWFCKHKALMNLRVHDG
KPVYDGEQVQIGGNESYYPVCRRHYFHPLTEEEMRN

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787490, Length=191, Percent_Identity=47.6439790575916, Blast_Score=190, Evalue=4e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 22642; Mature: 22511

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLFFHYGAMNSGKSIEILKVAHNYEEQDKKVILMTSGIDTRTAVGEISSRIGLRRDAL
CCEEEEEECCCCCCCCEEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCC
PIFDDTNILELITQASAQEDTACILIDEAQFLKKHHIIELAKVVDDLGIPVMTFGLKNDF
CCCCCCHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHH
RNELFEGTKYLLLYADKIVEMKTICWFCKHKALMNLRVHDGKPVYDGEQVQIGGNESYYP
HHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCEEEECCCCCCHH
VCRRHYFHPLTEEEMRN
HHHHHHCCCCCHHHHCC
>Mature Secondary Structure 
AQLFFHYGAMNSGKSIEILKVAHNYEEQDKKVILMTSGIDTRTAVGEISSRIGLRRDAL
CEEEEEECCCCCCCCEEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCC
PIFDDTNILELITQASAQEDTACILIDEAQFLKKHHIIELAKVVDDLGIPVMTFGLKNDF
CCCCCCHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHH
RNELFEGTKYLLLYADKIVEMKTICWFCKHKALMNLRVHDGKPVYDGEQVQIGGNESYYP
HHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCEEEECCCCCCHH
VCRRHYFHPLTEEEMRN
HHHHHHCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12566566 [H]