Click here to switch to the map view.

The map label for this gene is ywlC [H]

Identifier: 116493076

GI number: 116493076

Start: 1317511

End: 1318533

Strand: Reverse

Name: ywlC [H]

Synonym: PEPE_1328

Alternate gene names: 116493076

Gene position: 1318533-1317511 (Counterclockwise)

Preceding gene: 116493077

Following gene: 116493075

Centisome position: 71.96

GC content: 41.64

Gene sequence:

>1023_bases
ATGAGTAAATTATTTAGTTCTGATGAAATACAAGTAGCGGCTCAAGCCATCAAAGCTGGTGAATTAGTATCTTTCCCAAC
CGAAACCGTTTATGGACTGGGTGCGGATGCAACTAATCCAGAGGCAGTAAAAAAAGTTTATGCTGCTAAAGGCCGTCCTT
CGGATAATCCGCTAATTGTCCATGTTGCGGACCAAACAGAAGTTGCAAAGTTTGCTAATATTGACGACAAAAGCAAAAAA
TTAATGGATCAATTTTGGCCAGGACCACTAACCATTATCTTACCAATTAAAAAGGGAGCTTTAAATTCGATTGTTACAGG
TGGATTAGATACAGCTGCTTTTCGTAATCCGGCTACTCAAGTAACAATTGATTTAATTCGTGCAGCTGGAGTTCCATTGG
TGGGCCCATCCGCTAATACATCAGGAAAACCTAGCCCCACTAAACCGGAGCATGTGTTGCATGATTTGGACGGAAAAATT
GCTGGAGTTCTAGATGATGGGGAAACTACCATCGGTGTTGAATCAACGGTTTTAGATATGTCAAGTACAACGCCAAGTAT
CTTGCGGCCAGGGGCCATTACAGAACAAGCATTGGCACCCTTAATAGGTGAGGTCCAGACCGACCATCATAAAGTCGGAA
AAGATGAAGTTCCTAAGGCGCCTGGAATGAAATACAAACACTATGCTCCGAATGCCCAAGTATACATAGTGTCTGATCAG
GATTGGGACGGTGTCGTAGCTTGGCTCCAAAAGCATACTGATCAAACTATTGGAATTATGGCCACAAATGAAATTTTCGA
GACCAAAAAATTAGGAGAATTCGACCAAGTTCGATACATTTCCTTAGGGGTAGATTCTAAGACGGCTAGTCGAGAACTAT
TCGATGGATTACGAACCTTTGATGCTGATTCAGCAATAAAAACCATTTTTGCTCAAGGATTTGATAGAATAGGGATTGGC
GAGGCATACATGAATCGTCTCCAAAAATCTGCAGGTAACACATACTTTAGTGACATCGATTAG

Upstream 100 bases:

>100_bases
GTATTTCTTAGAAAAGAAGTATATTGACCAAGCGGAAGTTATAAAAGATCTTAGTCAACACGATCGAATTCTTTGGGTTA
AAAAGAAATAGGTGATAAAA

Downstream 100 bases:

>100_bases
GGGGAATTGGTCAATGAATTATACAAAACAAGATCCAGAATTATGGTCAGCAATTGAACGTGAAGAAAAGCGTCAGCAAC
ATAATATTGAATTAATTGCT

Product: translation factor SUA5

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSKLFSSDEIQVAAQAIKAGELVSFPTETVYGLGADATNPEAVKKVYAAKGRPSDNPLIVHVADQTEVAKFANIDDKSKK
LMDQFWPGPLTIILPIKKGALNSIVTGGLDTAAFRNPATQVTIDLIRAAGVPLVGPSANTSGKPSPTKPEHVLHDLDGKI
AGVLDDGETTIGVESTVLDMSSTTPSILRPGAITEQALAPLIGEVQTDHHKVGKDEVPKAPGMKYKHYAPNAQVYIVSDQ
DWDGVVAWLQKHTDQTIGIMATNEIFETKKLGEFDQVRYISLGVDSKTASRELFDGLRTFDADSAIKTIFAQGFDRIGIG
EAYMNRLQKSAGNTYFSDID

Sequences:

>Translated_340_residues
MSKLFSSDEIQVAAQAIKAGELVSFPTETVYGLGADATNPEAVKKVYAAKGRPSDNPLIVHVADQTEVAKFANIDDKSKK
LMDQFWPGPLTIILPIKKGALNSIVTGGLDTAAFRNPATQVTIDLIRAAGVPLVGPSANTSGKPSPTKPEHVLHDLDGKI
AGVLDDGETTIGVESTVLDMSSTTPSILRPGAITEQALAPLIGEVQTDHHKVGKDEVPKAPGMKYKHYAPNAQVYIVSDQ
DWDGVVAWLQKHTDQTIGIMATNEIFETKKLGEFDQVRYISLGVDSKTASRELFDGLRTFDADSAIKTIFAQGFDRIGIG
EAYMNRLQKSAGNTYFSDID
>Mature_339_residues
SKLFSSDEIQVAAQAIKAGELVSFPTETVYGLGADATNPEAVKKVYAAKGRPSDNPLIVHVADQTEVAKFANIDDKSKKL
MDQFWPGPLTIILPIKKGALNSIVTGGLDTAAFRNPATQVTIDLIRAAGVPLVGPSANTSGKPSPTKPEHVLHDLDGKIA
GVLDDGETTIGVESTVLDMSSTTPSILRPGAITEQALAPLIGEVQTDHHKVGKDEVPKAPGMKYKHYAPNAQVYIVSDQD
WDGVVAWLQKHTDQTIGIMATNEIFETKKLGEFDQVRYISLGVDSKTASRELFDGLRTFDADSAIKTIFAQGFDRIGIGE
AYMNRLQKSAGNTYFSDID

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=147, Percent_Identity=29.9319727891156, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87081864, Length=185, Percent_Identity=22.7027027027027, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321269, Length=367, Percent_Identity=36.2397820163488, Blast_Score=205, Evalue=1e-53,
Organism=Drosophila melanogaster, GI78707274, Length=178, Percent_Identity=29.2134831460674, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 36569; Mature: 36438

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLFSSDEIQVAAQAIKAGELVSFPTETVYGLGADATNPEAVKKVYAAKGRPSDNPLIV
CCCCCCCCHHHHHHHHHHCCCEECCCCHHHEECCCCCCCHHHHHHHHHHCCCCCCCCEEE
HVADQTEVAKFANIDDKSKKLMDQFWPGPLTIILPIKKGALNSIVTGGLDTAAFRNPATQ
EECCCHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCCCCHHHHCCCCHH
VTIDLIRAAGVPLVGPSANTSGKPSPTKPEHVLHDLDGKIAGVLDDGETTIGVESTVLDM
HHHHHHHHCCCCEECCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCEEECCCCEEEEC
SSTTPSILRPGAITEQALAPLIGEVQTDHHKVGKDEVPKAPGMKYKHYAPNAQVYIVSDQ
CCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEEECC
DWDGVVAWLQKHTDQTIGIMATNEIFETKKLGEFDQVRYISLGVDSKTASRELFDGLRTF
CCHHHHHHHHHHCCCEEEEEEECHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHC
DADSAIKTIFAQGFDRIGIGEAYMNRLQKSAGNTYFSDID
CCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SKLFSSDEIQVAAQAIKAGELVSFPTETVYGLGADATNPEAVKKVYAAKGRPSDNPLIV
CCCCCCCHHHHHHHHHHCCCEECCCCHHHEECCCCCCCHHHHHHHHHHCCCCCCCCEEE
HVADQTEVAKFANIDDKSKKLMDQFWPGPLTIILPIKKGALNSIVTGGLDTAAFRNPATQ
EECCCHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCCCCHHHHCCCCHH
VTIDLIRAAGVPLVGPSANTSGKPSPTKPEHVLHDLDGKIAGVLDDGETTIGVESTVLDM
HHHHHHHHCCCCEECCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCEEECCCCEEEEC
SSTTPSILRPGAITEQALAPLIGEVQTDHHKVGKDEVPKAPGMKYKHYAPNAQVYIVSDQ
CCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEEECC
DWDGVVAWLQKHTDQTIGIMATNEIFETKKLGEFDQVRYISLGVDSKTASRELFDGLRTF
CCHHHHHHHHHHCCCEEEEEEECHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHC
DADSAIKTIFAQGFDRIGIGEAYMNRLQKSAGNTYFSDID
CCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]