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The map label for this gene is cinA

Identifier: 116493025

GI number: 116493025

Start: 1267566

End: 1268807

Strand: Reverse

Name: cinA

Synonym: PEPE_1277

Alternate gene names: 116493025

Gene position: 1268807-1267566 (Counterclockwise)

Preceding gene: 116493026

Following gene: 116493024

Centisome position: 69.24

GC content: 39.61

Gene sequence:

>1242_bases
ATGAACGCTGAAATTATTTCAGTTGGTACAGAAATTTTGTTAGGAGAAATCGTCGATACTAACGCCGTTTATCTGAGCCA
GCTTTTTGCTAAATTAGGGATTGATGTTTTCAACAAAATAACTGTTGGAGATAACGAAAAAAACATCATGGATGCCTTAG
AAGTCGCTTCGAAGAGAAGTGATTTAGTGGTTACGATCGGCGGATTAGGTCCAACAGAGGACGATATCACTAAGCAATCC
TTGGCTAAATTTGTCGGAAAAAACTTAAAACACCATCCCGAGGCGCTACAACAAATTACAGACTATTTTAAAAAACAAAA
TCGGCCATTGACTAAAAATAATGAACGTCAGGCTTTATTACTGGATGGGGCTAAACCAATTCATAATCCTAATGGATTAG
CCCTGGGTATTTTTTATCACACAGAGCAAACCGATTATATTGTTTTGCCTGGACCGCCTTCGGAATTCGAACCTATGGTG
GATGAAAAGGTACTTCCGCTACTAAGCCAGCAATATGGTTTGGAGAAAACAATTCAATCTAAAACTCTGCATTTTGTTGG
AATCGGTGAGGCAGATTTAGCTGCTCGAGTAGATGAGATTGTTCGTAATCAAAGCAATCCTACTATCGCCCTTTACTTTA
AACCAACCGATGTGACAATTCGATTGACTGCCAAAGCTAATTCTAAGCTAGCTGCTGAGGAAATTTTAAATCATACTAAA
AAGCAACTACTAGATCGAGTTGGAGAATTCTTTTATGCAGAAGGTGACAGAGTTTCTTTCACCGATTTTGTCGTTAATCA
ATTGATTAAACGCAATATTTCATTAACAGCGGCAGAAAGTTTGACGGGGGGAGCTTTTGAAAGTACGGTTGTAGAAACTT
CTGGAGCAGCAACCATTTTTCCGGGAGGATTTGTAACATATGCTGATGAGGTCAAAAGTAAGTTGATAGGGGTTCAACCA
GCAACGATTGAAGAAAACACGGTTGTAAGTCGGCAAGTAGCGGAAGAGATGGCTAGAGGGGCTCAAAAGACGTTAGATAC
GGATATAGCGGTTAGTTTTACTGGAGTAGCTGGACCAGGGGCCTTAGAACATCACCAACCCGGAAACGTATGGATTGGTT
TAGCTAAACGTGATGGGTCAATAGTCACTAAAGAATTTAATTTTGTTGGTAACCGTGAAAAGATTCGGCACCTAGCCGTG
ATGAACGGATTTAGAATGATATGGGAAAATGTTATTAAATAA

Upstream 100 bases:

>100_bases
GGACTATAGCGAAATTTATGATTTTGTTATGGACCTTTTTTTAATACAAAAAAATAAAAACGAGTAAAATTACATATATA
AGCATTGAGGAGGAAAAAAA

Downstream 100 bases:

>100_bases
AACATTCGAACTTTTGTTCGCTTTTTTGTTGATTTTTATAAAATAACTATGTATCATACTAGTATAGAGAAACCCTAGGA
GGTTATTAATTGGCAGACGA

Product: competence/damage-inducible protein cinA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MNAEIISVGTEILLGEIVDTNAVYLSQLFAKLGIDVFNKITVGDNEKNIMDALEVASKRSDLVVTIGGLGPTEDDITKQS
LAKFVGKNLKHHPEALQQITDYFKKQNRPLTKNNERQALLLDGAKPIHNPNGLALGIFYHTEQTDYIVLPGPPSEFEPMV
DEKVLPLLSQQYGLEKTIQSKTLHFVGIGEADLAARVDEIVRNQSNPTIALYFKPTDVTIRLTAKANSKLAAEEILNHTK
KQLLDRVGEFFYAEGDRVSFTDFVVNQLIKRNISLTAAESLTGGAFESTVVETSGAATIFPGGFVTYADEVKSKLIGVQP
ATIEENTVVSRQVAEEMARGAQKTLDTDIAVSFTGVAGPGALEHHQPGNVWIGLAKRDGSIVTKEFNFVGNREKIRHLAV
MNGFRMIWENVIK

Sequences:

>Translated_413_residues
MNAEIISVGTEILLGEIVDTNAVYLSQLFAKLGIDVFNKITVGDNEKNIMDALEVASKRSDLVVTIGGLGPTEDDITKQS
LAKFVGKNLKHHPEALQQITDYFKKQNRPLTKNNERQALLLDGAKPIHNPNGLALGIFYHTEQTDYIVLPGPPSEFEPMV
DEKVLPLLSQQYGLEKTIQSKTLHFVGIGEADLAARVDEIVRNQSNPTIALYFKPTDVTIRLTAKANSKLAAEEILNHTK
KQLLDRVGEFFYAEGDRVSFTDFVVNQLIKRNISLTAAESLTGGAFESTVVETSGAATIFPGGFVTYADEVKSKLIGVQP
ATIEENTVVSRQVAEEMARGAQKTLDTDIAVSFTGVAGPGALEHHQPGNVWIGLAKRDGSIVTKEFNFVGNREKIRHLAV
MNGFRMIWENVIK
>Mature_413_residues
MNAEIISVGTEILLGEIVDTNAVYLSQLFAKLGIDVFNKITVGDNEKNIMDALEVASKRSDLVVTIGGLGPTEDDITKQS
LAKFVGKNLKHHPEALQQITDYFKKQNRPLTKNNERQALLLDGAKPIHNPNGLALGIFYHTEQTDYIVLPGPPSEFEPMV
DEKVLPLLSQQYGLEKTIQSKTLHFVGIGEADLAARVDEIVRNQSNPTIALYFKPTDVTIRLTAKANSKLAAEEILNHTK
KQLLDRVGEFFYAEGDRVSFTDFVVNQLIKRNISLTAAESLTGGAFESTVVETSGAATIFPGGFVTYADEVKSKLIGVQP
ATIEENTVVSRQVAEEMARGAQKTLDTDIAVSFTGVAGPGALEHHQPGNVWIGLAKRDGSIVTKEFNFVGNREKIRHLAV
MNGFRMIWENVIK

Specific function: Unknown

COG id: COG1058

COG function: function code R; Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CinA family

Homologues:

Organism=Homo sapiens, GI41872389, Length=94, Percent_Identity=39.3617021276596, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI41872403, Length=94, Percent_Identity=39.3617021276596, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI296434309, Length=94, Percent_Identity=39.3617021276596, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1788583, Length=286, Percent_Identity=31.1188811188811, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789052, Length=151, Percent_Identity=36.4238410596026, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1787818, Length=142, Percent_Identity=34.5070422535211, Blast_Score=83, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323832, Length=199, Percent_Identity=28.1407035175879, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CINA_PEDPA (Q03EQ4)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804760.1
- ProteinModelPortal:   Q03EQ4
- SMR:   Q03EQ4
- STRING:   Q03EQ4
- GeneID:   4417613
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1277
- NMPDR:   fig|278197.10.peg.1119
- eggNOG:   COG1058
- HOGENOM:   HBG449871
- OMA:   NPTVAPY
- PhylomeDB:   Q03EQ4
- BioCyc:   PPEN278197:PEPE_1277-MONOMER
- HAMAP:   MF_00226_B
- InterPro:   IPR008136
- InterPro:   IPR008135
- InterPro:   IPR001453
- Gene3D:   G3DSA:3.40.980.10
- PIRSF:   PIRSF006728
- SMART:   SM00852
- TIGRFAMs:   TIGR00199
- TIGRFAMs:   TIGR00200

Pfam domain/function: PF02464 CinA; PF00994 MoCF_biosynth; SSF53218 MoCF_biosynth

EC number: NA

Molecular weight: Translated: 45316; Mature: 45316

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAEIISVGTEILLGEIVDTNAVYLSQLFAKLGIDVFNKITVGDNEKNIMDALEVASKRS
CCCEEEECCHHHHHHHHHCCCHHHHHHHHHHHCHHHHHEEECCCCHHHHHHHHHHHCCCC
DLVVTIGGLGPTEDDITKQSLAKFVGKNLKHHPEALQQITDYFKKQNRPLTKNNERQALL
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEE
LDGAKPIHNPNGLALGIFYHTEQTDYIVLPGPPSEFEPMVDEKVLPLLSQQYGLEKTIQS
EECCCCCCCCCCEEEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCHHHHHHH
KTLHFVGIGEADLAARVDEIVRNQSNPTIALYFKPTDVTIRLTAKANSKLAAEEILNHTK
CEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEECCCCCHHHHHHHHHHH
KQLLDRVGEFFYAEGDRVSFTDFVVNQLIKRNISLTAAESLTGGAFESTVVETSGAATIF
HHHHHHHHHHEECCCCCEEHHHHHHHHHHHCCCCEEECCCCCCCCHHHHEEECCCCEEEC
PGGFVTYADEVKSKLIGVQPATIEENTVVSRQVAEEMARGAQKTLDTDIAVSFTGVAGPG
CCCCEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
ALEHHQPGNVWIGLAKRDGSIVTKEFNFVGNREKIRHLAVMNGFRMIWENVIK
CCCCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNAEIISVGTEILLGEIVDTNAVYLSQLFAKLGIDVFNKITVGDNEKNIMDALEVASKRS
CCCEEEECCHHHHHHHHHCCCHHHHHHHHHHHCHHHHHEEECCCCHHHHHHHHHHHCCCC
DLVVTIGGLGPTEDDITKQSLAKFVGKNLKHHPEALQQITDYFKKQNRPLTKNNERQALL
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEE
LDGAKPIHNPNGLALGIFYHTEQTDYIVLPGPPSEFEPMVDEKVLPLLSQQYGLEKTIQS
EECCCCCCCCCCEEEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCHHHHHHH
KTLHFVGIGEADLAARVDEIVRNQSNPTIALYFKPTDVTIRLTAKANSKLAAEEILNHTK
CEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEECCCCCHHHHHHHHHHH
KQLLDRVGEFFYAEGDRVSFTDFVVNQLIKRNISLTAAESLTGGAFESTVVETSGAATIF
HHHHHHHHHHEECCCCCEEHHHHHHHHHHHCCCCEEECCCCCCCCHHHHEEECCCCEEEC
PGGFVTYADEVKSKLIGVQPATIEENTVVSRQVAEEMARGAQKTLDTDIAVSFTGVAGPG
CCCCEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
ALEHHQPGNVWIGLAKRDGSIVTKEFNFVGNREKIRHLAVMNGFRMIWENVIK
CCCCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA