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The map label for this gene is pepQ [H]

Identifier: 116492999

GI number: 116492999

Start: 1237247

End: 1238341

Strand: Direct

Name: pepQ [H]

Synonym: PEPE_1251

Alternate gene names: 116492999

Gene position: 1237247-1238341 (Clockwise)

Preceding gene: 116492997

Following gene: 116493003

Centisome position: 67.52

GC content: 37.99

Gene sequence:

>1095_bases
ATGTCACAATTAGATAAAGTCCAAGCATGGGTTTCAGATCATAAGTTAGACGTTGCATATATTAGTAATTTTGAAAGTAT
TAAATACTTAACTGGTTTTGGTAGCGACCCTATCGAACGCGTTTTAGCTTTATTTGTTTTTCCTGATCATGAACCATTCT
TATTTGCTCCTGCACTAGAAATTGAAGCAATTAAAGATACTGGATGGAATCACCCCGTTTATGGTTATTTAGATCACGAG
AAGCCCTTTCAATTAATTGCTAAATATATTCGTGAACGCAATGCTAACCCTATTCACTGGGGAATTGAAAATAATAATCT
TACATTTGATCGTTATGAAGTACTTCGTTCTGAATTTCCAAATGCTAAATTTGAACAAAACTTAACTCCAGTTTTTGAAA
AACTTCGTATGATTAAAACTGCCGACGAAATCGAAAAATTAAATGCTGCTGGTGCAGAGGCTGATTACGCCTTTGAAGTT
GGTTTCAATGCAGTTGCCGCTGGTAAAACTGAAGCTGATGTTGCTGCTGAACTTGAATATGCTTTAAAAAAGCGTGGTGT
AATGGAAATGAGTTTTGATACTCTCATTCAAGCGGGCGCTCATGCTGCTGAACCCCATGGTGCAACTGGCATGAACCAAA
TTCAAAATAATGAATTAGTACTTTTCGACTTAGGTACCATCCATGATGGTTATATTAGTGATGCTTCTAGAACGGTCGCT
TTAGGAACTTTAAATGACAAACAAAAAGATATTTACAAAGTTTGTCTAGAAGCTCAATTAACTGCCCAAGCTTACGCCAA
ACCTGGAATTACTGCTGCTAGTTTAGATAAAGTCGCACGTGACATCATCGATAAGGCCGGTTACGGTGAATACTTCATTC
ATCGCCTAGGACATGGAATGGGTATGGGAGAACACGAATTCCCATCCATCATGGAAGGAAACGATTTAATCCTCCAAGAA
GGTATGTGTTTCTCAATCGAACCTGGTATCTATATCCCTGGCGTTGCTGGTGTTCGCATTGAAGACTGTGTTCACATCAC
TAAGGATGGTTGCCTACCATTTACCCATACTTCAAAAGAACTTAGATATCTATAA

Upstream 100 bases:

>100_bases
TTATCAAATTTTCAGCATACTTGCAACCTTTTTTTATTTTATTACCTATTTCCCTATGTGCTATAATCTAACTATCCGAA
TATAAGAAAGAAGAGATTAA

Downstream 100 bases:

>100_bases
TATTTCTACCAAAAAGCACTTCGGTTCTAAGCCGAAGCGCTTTTTATATAGCCTAATTATTCGGCAGAATATTGAGCTAA
ATATTCATCAAATGGCTTCA

Product: Mername-AA019 peptidase

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MSQLDKVQAWVSDHKLDVAYISNFESIKYLTGFGSDPIERVLALFVFPDHEPFLFAPALEIEAIKDTGWNHPVYGYLDHE
KPFQLIAKYIRERNANPIHWGIENNNLTFDRYEVLRSEFPNAKFEQNLTPVFEKLRMIKTADEIEKLNAAGAEADYAFEV
GFNAVAAGKTEADVAAELEYALKKRGVMEMSFDTLIQAGAHAAEPHGATGMNQIQNNELVLFDLGTIHDGYISDASRTVA
LGTLNDKQKDIYKVCLEAQLTAQAYAKPGITAASLDKVARDIIDKAGYGEYFIHRLGHGMGMGEHEFPSIMEGNDLILQE
GMCFSIEPGIYIPGVAGVRIEDCVHITKDGCLPFTHTSKELRYL

Sequences:

>Translated_364_residues
MSQLDKVQAWVSDHKLDVAYISNFESIKYLTGFGSDPIERVLALFVFPDHEPFLFAPALEIEAIKDTGWNHPVYGYLDHE
KPFQLIAKYIRERNANPIHWGIENNNLTFDRYEVLRSEFPNAKFEQNLTPVFEKLRMIKTADEIEKLNAAGAEADYAFEV
GFNAVAAGKTEADVAAELEYALKKRGVMEMSFDTLIQAGAHAAEPHGATGMNQIQNNELVLFDLGTIHDGYISDASRTVA
LGTLNDKQKDIYKVCLEAQLTAQAYAKPGITAASLDKVARDIIDKAGYGEYFIHRLGHGMGMGEHEFPSIMEGNDLILQE
GMCFSIEPGIYIPGVAGVRIEDCVHITKDGCLPFTHTSKELRYL
>Mature_363_residues
SQLDKVQAWVSDHKLDVAYISNFESIKYLTGFGSDPIERVLALFVFPDHEPFLFAPALEIEAIKDTGWNHPVYGYLDHEK
PFQLIAKYIRERNANPIHWGIENNNLTFDRYEVLRSEFPNAKFEQNLTPVFEKLRMIKTADEIEKLNAAGAEADYAFEVG
FNAVAAGKTEADVAAELEYALKKRGVMEMSFDTLIQAGAHAAEPHGATGMNQIQNNELVLFDLGTIHDGYISDASRTVAL
GTLNDKQKDIYKVCLEAQLTAQAYAKPGITAASLDKVARDIIDKAGYGEYFIHRLGHGMGMGEHEFPSIMEGNDLILQEG
MCFSIEPGIYIPGVAGVRIEDCVHITKDGCLPFTHTSKELRYL

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=251, Percent_Identity=29.0836653386454, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI149589008, Length=305, Percent_Identity=26.2295081967213, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI260593665, Length=305, Percent_Identity=26.2295081967213, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI93141226, Length=166, Percent_Identity=30.7228915662651, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1788728, Length=256, Percent_Identity=36.71875, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1789275, Length=262, Percent_Identity=26.3358778625954, Blast_Score=93, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17509539, Length=191, Percent_Identity=31.413612565445, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320922, Length=256, Percent_Identity=24.21875, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19920384, Length=254, Percent_Identity=25.1968503937008, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357079, Length=288, Percent_Identity=26.7361111111111, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 40599; Mature: 40468

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLDKVQAWVSDHKLDVAYISNFESIKYLTGFGSDPIERVLALFVFPDHEPFLFAPALE
CCHHHHHHHHHHCCCEEEHHHCCCHHHHHHHCCCCCHHHHHHEEEECCCCCCEEEECCCE
IEAIKDTGWNHPVYGYLDHEKPFQLIAKYIRERNANPIHWGIENNNLTFDRYEVLRSEFP
EEEECCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCC
NAKFEQNLTPVFEKLRMIKTADEIEKLNAAGAEADYAFEVGFNAVAAGKTEADVAAELEY
CCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEECCCCHHHHHHHHHH
ALKKRGVMEMSFDTLIQAGAHAAEPHGATGMNQIQNNELVLFDLGTIHDGYISDASRTVA
HHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCEEEEECCCCCCCCCCCCCCEEE
LGTLNDKQKDIYKVCLEAQLTAQAYAKPGITAASLDKVARDIIDKAGYGEYFIHRLGHGM
EECCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
GMGEHEFPSIMEGNDLILQEGMCFSIEPGIYIPGVAGVRIEDCVHITKDGCLPFTHTSKE
CCCCCCCCCCCCCCEEEEECCCEEEECCCEEECCCCCCCHHHHEEECCCCCCCCCCCCHH
LRYL
HCCC
>Mature Secondary Structure 
SQLDKVQAWVSDHKLDVAYISNFESIKYLTGFGSDPIERVLALFVFPDHEPFLFAPALE
CHHHHHHHHHHCCCEEEHHHCCCHHHHHHHCCCCCHHHHHHEEEECCCCCCEEEECCCE
IEAIKDTGWNHPVYGYLDHEKPFQLIAKYIRERNANPIHWGIENNNLTFDRYEVLRSEFP
EEEECCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCC
NAKFEQNLTPVFEKLRMIKTADEIEKLNAAGAEADYAFEVGFNAVAAGKTEADVAAELEY
CCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEECCCCHHHHHHHHHH
ALKKRGVMEMSFDTLIQAGAHAAEPHGATGMNQIQNNELVLFDLGTIHDGYISDASRTVA
HHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCEEEEECCCCCCCCCCCCCCEEE
LGTLNDKQKDIYKVCLEAQLTAQAYAKPGITAASLDKVARDIIDKAGYGEYFIHRLGHGM
EECCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
GMGEHEFPSIMEGNDLILQEGMCFSIEPGIYIPGVAGVRIEDCVHITKDGCLPFTHTSKE
CCCCCCCCCCCCCCEEEEECCCEEEECCCEEECCCCCCCHHHHEEECCCCCCCCCCCCHH
LRYL
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA