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The map label for this gene is ykuT [H]

Identifier: 116493003

GI number: 116493003

Start: 1241220

End: 1242065

Strand: Direct

Name: ykuT [H]

Synonym: PEPE_1255

Alternate gene names: 116493003

Gene position: 1241220-1242065 (Clockwise)

Preceding gene: 116492999

Following gene: 116493044

Centisome position: 67.74

GC content: 38.3

Gene sequence:

>846_bases
ATGAAAAACATGCTTACTATTGCAGCAGGCTTCCCATCATTAAAATCCAGCTTTACTCATATTGATTGGGAAAAAATTGG
TGTAGCTTTTATGGAACATTTTTTCCAACTCGTTCTAATCACCATTATTTTCTGGATTATTAATCGGATTGGTAAACATA
TCATCCGTAATAGTTTTCAACATCACGATCCAATTGAAAAACAATCCGCTCGTTCACAAACCGTTTACGCAGTGGTTAAA
AATATTTTCAAGTATTCCGTCCTATTCTTTTACGTCTATACTATTTTATCAAATTTAGGAGTACCAGTGGGCACTTTATT
GGCCGGTGCTGGAATCTTAAGTGTTGCGATTGGTCTCGGGACTCAAGGGATTGTGTCCGATGTTATTAACGGCCTAACTA
TTTTAATTGAAGGCCAACTACGTGTTGGTGATAGTGTTACGATTCAATCCATCGATGGAACCGTCGTTTCAATCGGTTTA
CGAACCATTGAACTTCAAGCACTCGATGGTACTTTACATTACCTACCGAATCGCTCCATTTCAACAATTTCAAATCATTC
TCGCGGAAGTCAAACTATTTCCATCTTTCTACGAATCAGTGATCCGTTTGAAATTGACCGTGCTAAAGACTTGTTGCGTG
ACCAACTAGCTTCGATTAAACAAGACACCGATAAAATTAAAGCTACTCCCATTGTTCTCGCTCCTGTAGTCGAAAAGACT
TACGGATATCTGGGAGTTCAAATCTCTGCCAAGGTTAAGGCCGGCTATCAAACTCCGATGAAAACTATGATTTTGGATCG
TTGTCTACGAACTTTAGCCCAAGAACAAATTAAAATTCAAAATTAG

Upstream 100 bases:

>100_bases
AGAATAGCATTACAAATAATTAAGTGCAATTAAAACCCCTACTTATTCGCTACAAAATTCTGTTAGAATAGTATTATTAC
TGAAAGGACGATTTTTATTT

Downstream 100 bases:

>100_bases
TAAAAAAGTATGCCATCTTATAATCACCCAAAGTTAGATCCAATTCACTCTACTACGGGTTCAATGTTGATGGCATACTT
TTTTATTTATTCCCAGAATT

Product: small-conductance mechanosensitive channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MKNMLTIAAGFPSLKSSFTHIDWEKIGVAFMEHFFQLVLITIIFWIINRIGKHIIRNSFQHHDPIEKQSARSQTVYAVVK
NIFKYSVLFFYVYTILSNLGVPVGTLLAGAGILSVAIGLGTQGIVSDVINGLTILIEGQLRVGDSVTIQSIDGTVVSIGL
RTIELQALDGTLHYLPNRSISTISNHSRGSQTISIFLRISDPFEIDRAKDLLRDQLASIKQDTDKIKATPIVLAPVVEKT
YGYLGVQISAKVKAGYQTPMKTMILDRCLRTLAQEQIKIQN

Sequences:

>Translated_281_residues
MKNMLTIAAGFPSLKSSFTHIDWEKIGVAFMEHFFQLVLITIIFWIINRIGKHIIRNSFQHHDPIEKQSARSQTVYAVVK
NIFKYSVLFFYVYTILSNLGVPVGTLLAGAGILSVAIGLGTQGIVSDVINGLTILIEGQLRVGDSVTIQSIDGTVVSIGL
RTIELQALDGTLHYLPNRSISTISNHSRGSQTISIFLRISDPFEIDRAKDLLRDQLASIKQDTDKIKATPIVLAPVVEKT
YGYLGVQISAKVKAGYQTPMKTMILDRCLRTLAQEQIKIQN
>Mature_281_residues
MKNMLTIAAGFPSLKSSFTHIDWEKIGVAFMEHFFQLVLITIIFWIINRIGKHIIRNSFQHHDPIEKQSARSQTVYAVVK
NIFKYSVLFFYVYTILSNLGVPVGTLLAGAGILSVAIGLGTQGIVSDVINGLTILIEGQLRVGDSVTIQSIDGTVVSIGL
RTIELQALDGTLHYLPNRSISTISNHSRGSQTISIFLRISDPFEIDRAKDLLRDQLASIKQDTDKIKATPIVLAPVVEKT
YGYLGVQISAKVKAGYQTPMKTMILDRCLRTLAQEQIKIQN

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI87081787, Length=192, Percent_Identity=30.7291666666667, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786670, Length=141, Percent_Identity=31.9148936170213, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 31143; Mature: 31143

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNMLTIAAGFPSLKSSFTHIDWEKIGVAFMEHFFQLVLITIIFWIINRIGKHIIRNSFQ
CCCEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HHDPIEKQSARSQTVYAVVKNIFKYSVLFFYVYTILSNLGVPVGTLLAGAGILSVAIGLG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
TQGIVSDVINGLTILIEGQLRVGDSVTIQSIDGTVVSIGLRTIELQALDGTLHYLPNRSI
CHHHHHHHHCCEEEEEECCEECCCCEEEEECCCEEEEEEEEEEEEEEECCHHHHCCCCCH
STISNHSRGSQTISIFLRISDPFEIDRAKDLLRDQLASIKQDTDKIKATPIVLAPVVEKT
HHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHH
YGYLGVQISAKVKAGYQTPMKTMILDRCLRTLAQEQIKIQN
CCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKNMLTIAAGFPSLKSSFTHIDWEKIGVAFMEHFFQLVLITIIFWIINRIGKHIIRNSFQ
CCCEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HHDPIEKQSARSQTVYAVVKNIFKYSVLFFYVYTILSNLGVPVGTLLAGAGILSVAIGLG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
TQGIVSDVINGLTILIEGQLRVGDSVTIQSIDGTVVSIGLRTIELQALDGTLHYLPNRSI
CHHHHHHHHCCEEEEEECCEECCCCEEEEECCCEEEEEEEEEEEEEEECCHHHHCCCCCH
STISNHSRGSQTISIFLRISDPFEIDRAKDLLRDQLASIKQDTDKIKATPIVLAPVVEKT
HHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHH
YGYLGVQISAKVKAGYQTPMKTMILDRCLRTLAQEQIKIQN
CCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]