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The map label for this gene is comGA [H]

Identifier: 116492986

GI number: 116492986

Start: 1224622

End: 1225584

Strand: Reverse

Name: comGA [H]

Synonym: PEPE_1238

Alternate gene names: 116492986

Gene position: 1225584-1224622 (Counterclockwise)

Preceding gene: 116492987

Following gene: 116492985

Centisome position: 66.88

GC content: 38.21

Gene sequence:

>963_bases
ATGAATATAACCAGTAAGCTAAATCAAATCATCCAAGAGTGTCTTGTCAATCGGGATAGTGATTTATTCATTATGCCGCG
ATTTGATAAATATCAATTATTATATCGAGATGCGGGAGGGTACCGAAAGTCTGCCCTGATTGATAGAGATGAAGCAGAAC
AAATTATGATGTATATCAAATATCGGGCTGATATGGGGATCAGTGAGCGACGAAGGCCACAAAGTGGGGCGATGACTTGG
TTAAACCGCCAGGGAGAATTAGTTAATTTACGAATATCTACGGTGGGCGATTTTTTGGATCGACCTTCGATGGTAATTCG
TTTTATATATGTACTAAAGCAAGATGAACATATTTTGGATAGCGAAAGTATGGAAAAAATCCAACTAGCAACTAAGCTTC
GGGGATTAATGGTTTTTTCAGGTCCAATGGGCTCCGGAAAAACAACGTTGATTTACGAAGTAGCTCGTAAATTAAGTGAA
ACCAAGATGGTAATGTCAATTGAAGATCCGGTAGAAATTCGCGAACATAATTTTTTGCAACTGCAAGTTAATGAAAAATC
GGGGATGTCGTATCAAGAATTACTGAAAAATGGTTTAAGGAATCGACCAGATGTTTTTATTATTGGCGAAATCCGAGATG
GTAAAACTGCAGAAATTGCGATTCAAGCTGCGTTAAGTGGTCATTTAGTTTTAACCACCGTTCACTCTAAAAGTACCCAA
GGGGTATGGAATCGAATTGTTGAATTAGGTGTACGAGAAGAGCACTTAAAAGAAGCCTTAACGGCAGTTATCTATCAAAG
AATGATTCCTGCTAAGGTTGGTGATTTAAAAATTATGGCAGAAATTAAATCATTCCATCCGGCCCTGAAAGGAACAAAGA
AGAAGTGGAGAGAACGACTAGAGGAGTGGAAGGAAAGTGGCCAAATTACTAAAGAAGTATTTGAAGATTTCCAATACGGA
TAG

Upstream 100 bases:

>100_bases
CATGAACCTGAATGGTTCATGTTTTTTTGTTGTCTAAATTTAGCTAATTAAAAAATAAATGTTCTGTTTTTGAGTATATA
TACGGTGAGGAGGACGTGAG

Downstream 100 bases:

>100_bases
AATCCAATTAAATGATCAAGCGTTTATTTTTTCAACTATGGTTGATTTAATGAAAATGGGCGTTTCGATTCGCAAGAGTG
TGGAACTTGTTCGAATTATG

Product: Type II secretory pathway/competence component, ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MNITSKLNQIIQECLVNRDSDLFIMPRFDKYQLLYRDAGGYRKSALIDRDEAEQIMMYIKYRADMGISERRRPQSGAMTW
LNRQGELVNLRISTVGDFLDRPSMVIRFIYVLKQDEHILDSESMEKIQLATKLRGLMVFSGPMGSGKTTLIYEVARKLSE
TKMVMSIEDPVEIREHNFLQLQVNEKSGMSYQELLKNGLRNRPDVFIIGEIRDGKTAEIAIQAALSGHLVLTTVHSKSTQ
GVWNRIVELGVREEHLKEALTAVIYQRMIPAKVGDLKIMAEIKSFHPALKGTKKKWRERLEEWKESGQITKEVFEDFQYG

Sequences:

>Translated_320_residues
MNITSKLNQIIQECLVNRDSDLFIMPRFDKYQLLYRDAGGYRKSALIDRDEAEQIMMYIKYRADMGISERRRPQSGAMTW
LNRQGELVNLRISTVGDFLDRPSMVIRFIYVLKQDEHILDSESMEKIQLATKLRGLMVFSGPMGSGKTTLIYEVARKLSE
TKMVMSIEDPVEIREHNFLQLQVNEKSGMSYQELLKNGLRNRPDVFIIGEIRDGKTAEIAIQAALSGHLVLTTVHSKSTQ
GVWNRIVELGVREEHLKEALTAVIYQRMIPAKVGDLKIMAEIKSFHPALKGTKKKWRERLEEWKESGQITKEVFEDFQYG
>Mature_320_residues
MNITSKLNQIIQECLVNRDSDLFIMPRFDKYQLLYRDAGGYRKSALIDRDEAEQIMMYIKYRADMGISERRRPQSGAMTW
LNRQGELVNLRISTVGDFLDRPSMVIRFIYVLKQDEHILDSESMEKIQLATKLRGLMVFSGPMGSGKTTLIYEVARKLSE
TKMVMSIEDPVEIREHNFLQLQVNEKSGMSYQELLKNGLRNRPDVFIIGEIRDGKTAEIAIQAALSGHLVLTTVHSKSTQ
GVWNRIVELGVREEHLKEALTAVIYQRMIPAKVGDLKIMAEIKSFHPALKGTKKKWRERLEEWKESGQITKEVFEDFQYG

Specific function: Required for uptake of DNA by competent cells [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1786296, Length=272, Percent_Identity=36.3970588235294, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1789723, Length=292, Percent_Identity=30.4794520547945, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI87082188, Length=145, Percent_Identity=31.0344827586207, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 36949; Mature: 36949

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNITSKLNQIIQECLVNRDSDLFIMPRFDKYQLLYRDAGGYRKSALIDRDEAEQIMMYIK
CCHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEECCCCCHHHHCCCCHHHHHHHHHHH
YRADMGISERRRPQSGAMTWLNRQGELVNLRISTVGDFLDRPSMVIRFIYVLKQDEHILD
HHCCCCCHHHCCCCCCCHHHCCCCCCEEEEEHHHHHHHHCCHHHHHHHHHHHHCCCHHCC
SESMEKIQLATKLRGLMVFSGPMGSGKTTLIYEVARKLSETKMVMSIEDPVEIREHNFLQ
CHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHEEEEECCCHHHCCCCEEE
LQVNEKSGMSYQELLKNGLRNRPDVFIIGEIRDGKTAEIAIQAALSGHLVLTTVHSKSTQ
EEECCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCHHEEEEEECCCCEEEEEECCCCCH
GVWNRIVELGVREEHLKEALTAVIYQRMIPAKVGDLKIMAEIKSFHPALKGTKKKWRERL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
EEWKESGQITKEVFEDFQYG
HHHHHCCCHHHHHHHHCCCC
>Mature Secondary Structure
MNITSKLNQIIQECLVNRDSDLFIMPRFDKYQLLYRDAGGYRKSALIDRDEAEQIMMYIK
CCHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEECCCCCHHHHCCCCHHHHHHHHHHH
YRADMGISERRRPQSGAMTWLNRQGELVNLRISTVGDFLDRPSMVIRFIYVLKQDEHILD
HHCCCCCHHHCCCCCCCHHHCCCCCCEEEEEHHHHHHHHCCHHHHHHHHHHHHCCCHHCC
SESMEKIQLATKLRGLMVFSGPMGSGKTTLIYEVARKLSETKMVMSIEDPVEIREHNFLQ
CHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHEEEEECCCHHHCCCCEEE
LQVNEKSGMSYQELLKNGLRNRPDVFIIGEIRDGKTAEIAIQAALSGHLVLTTVHSKSTQ
EEECCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCHHEEEEEECCCCEEEEEECCCCCH
GVWNRIVELGVREEHLKEALTAVIYQRMIPAKVGDLKIMAEIKSFHPALKGTKKKWRERL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
EEWKESGQITKEVFEDFQYG
HHHHHCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2507524; 8969508; 9384377; 9422590; 9723928 [H]