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The map label for this gene is rbsK [H]

Identifier: 116492987

GI number: 116492987

Start: 1225703

End: 1226614

Strand: Reverse

Name: rbsK [H]

Synonym: PEPE_1239

Alternate gene names: 116492987

Gene position: 1226614-1225703 (Counterclockwise)

Preceding gene: 116492988

Following gene: 116492986

Centisome position: 66.94

GC content: 39.91

Gene sequence:

>912_bases
ATGAGTAATAAAGTGGTCGTTCTTGGCAGTCTAAATGTGGATACAATTTTACAAGTTGGACGGTTTCCAGAACCAGGGGA
AACATTGGCTTTAAAAGATAAGCAAATGGCCGGTGGTGGAAAAGGAGCCAATCAAGCAATTGCAGCGGCTCGTTCAGGTG
CAGAAACTAGTTTTATTGGTAAAGTCGGAACCGATGCGAATGGGCAATTTATGCTTAAACAATTACTTGATAGCGGGGTT
TCAACGGAATATGTGGCAACCTCCAAAGTAGCGGATACAGGTCAAGCTTTTGTAATGCTCGAAAATACCGGTGAAAATCG
AATTTTAATTTATGGAGGCTCTAATGCTGAGTTAAATGAGGATGATGTCAATAAGGCAGCTGAAAAAATTCAACAAGCTG
ATTTTATCGTTGCTCAATTGGAAACTCCACTTGAAACAACTAAATATGCCTTCGAAATTGCTAAACAAGCTGGAATCAAA
ACAATTTTAAATCCTGCTCCTGCAGTTAAAAATTTACCTAAGGAATTAATTCAATTGACGGATGTTATCACGCCCAATGA
AACTGAAGCTGAAATTTTAACAGGCGTTACGGTTGTGGACGATGCTTCAATGAAAGAAGCAGCTCAAAGATTACATAAAA
TGGGAGTCCAGACGGTCATTATTACCCTAGGTAGTAAAGGGGTTTATTATGATGATGGCGACGTGAGCGGCATTGTTCCG
GCGTTTAAAGTGCATGCGATTGATACAACAGCAGCTGGAGATACGTTCCTAGGATCTTTTAGTTCGGAATTGAAGCCAGA
TTTAAGTAACTTAAAAGAAGCCATTATGTATGGCAATAAAGCTTCCTCGCTGGCTGTTCAAAAGATGGGTGCCCAACCAT
CAATTCCAACACGCAAAGAAGTTCTAAAATAA

Upstream 100 bases:

>100_bases
AGGCAAGGACAATTAAGTTCTTGCTTTTTTTATTTAATCAAGAATTTGAAAATTTAGTATGATAAAATTTACTTATATAA
CATATAACTGAGGTGGCGTA

Downstream 100 bases:

>100_bases
ATAGTCATAACAAAAAAACATGAACCTGAATGGTTCATGTTTTTTTGTTGTCTAAATTTAGCTAATTAAAAAATAAATGT
TCTGTTTTTGAGTATATATA

Product: ribokinase family sugar kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSNKVVVLGSLNVDTILQVGRFPEPGETLALKDKQMAGGGKGANQAIAAARSGAETSFIGKVGTDANGQFMLKQLLDSGV
STEYVATSKVADTGQAFVMLENTGENRILIYGGSNAELNEDDVNKAAEKIQQADFIVAQLETPLETTKYAFEIAKQAGIK
TILNPAPAVKNLPKELIQLTDVITPNETEAEILTGVTVVDDASMKEAAQRLHKMGVQTVIITLGSKGVYYDDGDVSGIVP
AFKVHAIDTTAAGDTFLGSFSSELKPDLSNLKEAIMYGNKASSLAVQKMGAQPSIPTRKEVLK

Sequences:

>Translated_303_residues
MSNKVVVLGSLNVDTILQVGRFPEPGETLALKDKQMAGGGKGANQAIAAARSGAETSFIGKVGTDANGQFMLKQLLDSGV
STEYVATSKVADTGQAFVMLENTGENRILIYGGSNAELNEDDVNKAAEKIQQADFIVAQLETPLETTKYAFEIAKQAGIK
TILNPAPAVKNLPKELIQLTDVITPNETEAEILTGVTVVDDASMKEAAQRLHKMGVQTVIITLGSKGVYYDDGDVSGIVP
AFKVHAIDTTAAGDTFLGSFSSELKPDLSNLKEAIMYGNKASSLAVQKMGAQPSIPTRKEVLK
>Mature_302_residues
SNKVVVLGSLNVDTILQVGRFPEPGETLALKDKQMAGGGKGANQAIAAARSGAETSFIGKVGTDANGQFMLKQLLDSGVS
TEYVATSKVADTGQAFVMLENTGENRILIYGGSNAELNEDDVNKAAEKIQQADFIVAQLETPLETTKYAFEIAKQAGIKT
ILNPAPAVKNLPKELIQLTDVITPNETEAEILTGVTVVDDASMKEAAQRLHKMGVQTVIITLGSKGVYYDDGDVSGIVPA
FKVHAIDTTAAGDTFLGSFSSELKPDLSNLKEAIMYGNKASSLAVQKMGAQPSIPTRKEVLK

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=297, Percent_Identity=40.7407407407407, Blast_Score=199, Evalue=3e-51,
Organism=Escherichia coli, GI1790193, Length=300, Percent_Identity=46.3333333333333, Blast_Score=231, Evalue=3e-62,
Organism=Escherichia coli, GI87082343, Length=300, Percent_Identity=30.3333333333333, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI87081971, Length=311, Percent_Identity=29.2604501607717, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788491, Length=291, Percent_Identity=27.4914089347079, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788417, Length=303, Percent_Identity=23.1023102310231, Blast_Score=75, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17532905, Length=306, Percent_Identity=36.6013071895425, Blast_Score=177, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6319884, Length=335, Percent_Identity=31.044776119403, Blast_Score=126, Evalue=4e-30,
Organism=Drosophila melanogaster, GI20128807, Length=303, Percent_Identity=36.963696369637, Blast_Score=168, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24583886, Length=302, Percent_Identity=31.7880794701987, Blast_Score=135, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32050; Mature: 31919

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKVVVLGSLNVDTILQVGRFPEPGETLALKDKQMAGGGKGANQAIAAARSGAETSFIG
CCCCEEEEECCCHHHHHHHCCCCCCCCEEEEECHHHCCCCCCCHHHHHHHHCCCCCEEEE
KVGTDANGQFMLKQLLDSGVSTEYVATSKVADTGQAFVMLENTGENRILIYGGSNAELNE
CCCCCCCHHHHHHHHHHCCCCCCEEEHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCH
DDVNKAAEKIQQADFIVAQLETPLETTKYAFEIAKQAGIKTILNPAPAVKNLPKELIQLT
HHHHHHHHHHHHHHHEEEHHCCCHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHH
DVITPNETEAEILTGVTVVDDASMKEAAQRLHKMGVQTVIITLGSKGVYYDDGDVSGIVP
HCCCCCCCCHHHHCCEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCEEECCCCCCCCCC
AFKVHAIDTTAAGDTFLGSFSSELKPDLSNLKEAIMYGNKASSLAVQKMGAQPSIPTRKE
CEEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHH
VLK
HCC
>Mature Secondary Structure 
SNKVVVLGSLNVDTILQVGRFPEPGETLALKDKQMAGGGKGANQAIAAARSGAETSFIG
CCCEEEEECCCHHHHHHHCCCCCCCCEEEEECHHHCCCCCCCHHHHHHHHCCCCCEEEE
KVGTDANGQFMLKQLLDSGVSTEYVATSKVADTGQAFVMLENTGENRILIYGGSNAELNE
CCCCCCCHHHHHHHHHHCCCCCCEEEHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCH
DDVNKAAEKIQQADFIVAQLETPLETTKYAFEIAKQAGIKTILNPAPAVKNLPKELIQLT
HHHHHHHHHHHHHHHEEEHHCCCHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHH
DVITPNETEAEILTGVTVVDDASMKEAAQRLHKMGVQTVIITLGSKGVYYDDGDVSGIVP
HCCCCCCCCHHHHCCEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCEEECCCCCCCCCC
AFKVHAIDTTAAGDTFLGSFSSELKPDLSNLKEAIMYGNKASSLAVQKMGAQPSIPTRKE
CEEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHH
VLK
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]