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The map label for this gene is ppnK

Identifier: 116492963

GI number: 116492963

Start: 1202852

End: 1203661

Strand: Reverse

Name: ppnK

Synonym: PEPE_1202

Alternate gene names: 116492963

Gene position: 1203661-1202852 (Counterclockwise)

Preceding gene: 116492964

Following gene: 116492962

Centisome position: 65.69

GC content: 38.27

Gene sequence:

>810_bases
ATGAGAGTAGCTATTTATCATTCAAGTGATGAGCATTCCATTCAAGTTGGTAAAGATTTAGCAAAGATTTTATCTCAAAA
TGAGATTGTAATTGATAACGAAAAACCTACGGTGGTGATTACCATTGGGGGGGATGGGACGTTACTATCTGCCGTTCAAA
AATATCTTAATCTTCTTGAAGAGGTCCGATTTGTAGGCGTACATACGGGACATCTAGGTTTTTACACAGACTGGCGCGAA
TATGAATTGGAAACCTTAGTTAAGGCTTTGAAGAGTGATGGAGGAGCTGAAGTTTCGTATCCATTATTAAATATTGATGT
GACTCATACAGATGGTTCACACATTAGTTATAAGGCAGTTAACGAGTCCACATTACGTAAATTGTCTGGGACAATGGTAG
CGGATGTATTGATTGGTGATAATCTATTTGAACGTTTTCGTGGGGACGGTCTGTGTATTTCTACACCAACAGGATCAACG
GCATACAATCGTTCGGTAGGTGGAGCGATTGTACATCCTAGATTAGAAGTATTACAAATGGCTGAAATTGCGTCAATTAA
TAATCGCGTTTTTCGAACGGTGGGAGCTTCTTTAATTATGGCGCCCAACGAAACTATTACAATTAGGCCAGTACCTAGTT
TCCATCGAACCTACAATTTTACAGCAGATCGTATCGATTTACTGGATAAACATGTCAAAGAGGTTCACTATAGCATTGAT
GAACAAAAAGTGAAATTCTTAAAGTATCGTCATACTGGATTTTGGAATCGAGTTCGAAATTCCTTCATTGGTAGTATCGA
TGAAGTTTAG

Upstream 100 bases:

>100_bases
TGCAGAAGGCCTCGGTTAAATCATATGAATTAGACAAAGAAATGTCTGAAATCAGAAAACAAATTTTATTAGCACAAAAA
GAACAAAAGGATGTCTAAAT

Downstream 100 bases:

>100_bases
ATGGATAGTTAACTTTGAGAGTCGGCAGCACCTACGGACTTTCTTGGGTAGGAAAAGAATTTCAAGGTCATTATTAAAAA
GTATTAAGTTTAATGGCGGT

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MRVAIYHSSDEHSIQVGKDLAKILSQNEIVIDNEKPTVVITIGGDGTLLSAVQKYLNLLEEVRFVGVHTGHLGFYTDWRE
YELETLVKALKSDGGAEVSYPLLNIDVTHTDGSHISYKAVNESTLRKLSGTMVADVLIGDNLFERFRGDGLCISTPTGST
AYNRSVGGAIVHPRLEVLQMAEIASINNRVFRTVGASLIMAPNETITIRPVPSFHRTYNFTADRIDLLDKHVKEVHYSID
EQKVKFLKYRHTGFWNRVRNSFIGSIDEV

Sequences:

>Translated_269_residues
MRVAIYHSSDEHSIQVGKDLAKILSQNEIVIDNEKPTVVITIGGDGTLLSAVQKYLNLLEEVRFVGVHTGHLGFYTDWRE
YELETLVKALKSDGGAEVSYPLLNIDVTHTDGSHISYKAVNESTLRKLSGTMVADVLIGDNLFERFRGDGLCISTPTGST
AYNRSVGGAIVHPRLEVLQMAEIASINNRVFRTVGASLIMAPNETITIRPVPSFHRTYNFTADRIDLLDKHVKEVHYSID
EQKVKFLKYRHTGFWNRVRNSFIGSIDEV
>Mature_269_residues
MRVAIYHSSDEHSIQVGKDLAKILSQNEIVIDNEKPTVVITIGGDGTLLSAVQKYLNLLEEVRFVGVHTGHLGFYTDWRE
YELETLVKALKSDGGAEVSYPLLNIDVTHTDGSHISYKAVNESTLRKLSGTMVADVLIGDNLFERFRGDGLCISTPTGST
AYNRSVGGAIVHPRLEVLQMAEIASINNRVFRTVGASLIMAPNETITIRPVPSFHRTYNFTADRIDLLDKHVKEVHYSID
EQKVKFLKYRHTGFWNRVRNSFIGSIDEV

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family

Homologues:

Organism=Escherichia coli, GI1788968, Length=149, Percent_Identity=31.5436241610738, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPNK_PEDPA (Q03EW6)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804698.1
- ProteinModelPortal:   Q03EW6
- SMR:   Q03EW6
- STRING:   Q03EW6
- GeneID:   4417935
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1202
- NMPDR:   fig|278197.10.peg.1060
- eggNOG:   COG0061
- HOGENOM:   HBG314020
- OMA:   TISFANC
- ProtClustDB:   PRK04885
- BioCyc:   PPEN278197:PEPE_1202-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00361
- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504
- Gene3D:   G3DSA:2.60.200.30
- Gene3D:   G3DSA:3.40.50.10330
- PANTHER:   PTHR20275

Pfam domain/function: PF01513 NAD_kinase; SSF111331 ATP-NAD_kinase_PpnK-typ

EC number: =2.7.1.23

Molecular weight: Translated: 30105; Mature: 30105

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVAIYHSSDEHSIQVGKDLAKILSQNEIVIDNEKPTVVITIGGDGTLLSAVQKYLNLLE
CEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHH
EVRFVGVHTGHLGFYTDWREYELETLVKALKSDGGAEVSYPLLNIDVTHTDGSHISYKAV
HHHHHEEEECCCCEECCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCEEEEEEC
NESTLRKLSGTMVADVLIGDNLFERFRGDGLCISTPTGSTAYNRSVGGAIVHPRLEVLQM
CHHHHHHHHCHHHHHHHHCCHHHHHHCCCCEEEECCCCCCCCCCCCCCEEECCHHHHHHH
AEIASINNRVFRTVGASLIMAPNETITIRPVPSFHRTYNFTADRIDLLDKHVKEVHYSID
HHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCHHHEECCCHHHHHHHHHHHHHHHHCCC
EQKVKFLKYRHTGFWNRVRNSFIGSIDEV
HHHHHHHHHHCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRVAIYHSSDEHSIQVGKDLAKILSQNEIVIDNEKPTVVITIGGDGTLLSAVQKYLNLLE
CEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHH
EVRFVGVHTGHLGFYTDWREYELETLVKALKSDGGAEVSYPLLNIDVTHTDGSHISYKAV
HHHHHEEEECCCCEECCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCEEEEEEC
NESTLRKLSGTMVADVLIGDNLFERFRGDGLCISTPTGSTAYNRSVGGAIVHPRLEVLQM
CHHHHHHHHCHHHHHHHHCCHHHHHHCCCCEEEECCCCCCCCCCCCCCEEECCHHHHHHH
AEIASINNRVFRTVGASLIMAPNETITIRPVPSFHRTYNFTADRIDLLDKHVKEVHYSID
HHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCHHHEECCCHHHHHHHHHHHHHHHHCCC
EQKVKFLKYRHTGFWNRVRNSFIGSIDEV
HHHHHHHHHHCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA