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The map label for this gene is murG

Identifier: 116492947

GI number: 116492947

Start: 1186387

End: 1187475

Strand: Reverse

Name: murG

Synonym: PEPE_1186

Alternate gene names: 116492947

Gene position: 1187475-1186387 (Counterclockwise)

Preceding gene: 116492948

Following gene: 116492946

Centisome position: 64.8

GC content: 37.56

Gene sequence:

>1089_bases
ATGAGACTGATGGTTTCTGGTGGTGGAACTGGTGGACATATTTATCCAGCCCTAGCACTGATTAAACAAGTTAAACAAAG
TGAACCTGATTCACAGATTTTGTACGTTGGTACAAGTAAGGGATTAGAAAGTAAAATTGTCCCAGATAGTGGAATTGATT
TTAAAACCATAAATATCCAAGGATTCAAACGTTCACTTTCACTTGAAAATTTTAAGACAATCGGACTTTTCTTAAGTAGC
GTGGTTAAAGCGCGTAAGATGGTTAAGGAATTTAAACCAGATGTAGTCTTGGGAACGGGGGGCTACGTTAGTGGTGCGGT
TGTATTTGCAGCTAGTATGATGGGTGTACCTACTGTGATTCACGAACAAAATAGTGTGGTTGGCGTTACCAATAAGTTTT
TGAGTAAGTTCGTTAAAAAAATTGCTATTTCGTTTGAGGCGGCTGCAAGTCAATTTCCTACCAAGAAAGTTGTGTTAACT
GGTAATCCTCGCGCTACTGAAGTAGCACAGATTAAACCAAGTGGACTAAGTCAATTTGGTCTAGACGATAAGGTGCCTAC
CGTATTGATTTTTGGTGGAAGCCGTGGAGCTGAGAAGATTAATCAGGTCACTATCGACACCTTGGAAGAATTAATGGAAC
GTCCATATCAAACAATATTTGTAACAGGAAGAGTTCATTTCGAACGTTTAACCAAAGATATTGATTTGGCTAAATATCAA
GGCAAAATAGCTATTTTACCTTACATTGCAAATATGCCAGAAATTCTTTCCAATATGGAAGTAATTGTGGGGCGAGCTGG
AGCAACTAGTTTAGCAGAAATTACTTCTTTAGGAATACCGTCAATTTTAATTCCTAGCCCATATGTAACCAATGATCATC
AAACAAAAAATGCAATGAGTCTGGTTAATAATGATGCAGCAGAGATTATCAAAGAAAGTGATCTTACTTCCGAAGCATTG
ATTAATACGCTTGATACATTGATGCTAGATCAGAAATTTCGAAACGTAATGGCAGAAAACGCTAAGAAAATGGGTCAACC
ACGTGCTGCTGAAAATCTTTATGATGTTTTGAAATCGGTTAGTAAGTAG

Upstream 100 bases:

>100_bases
TCACCGGCAGCGGCTAGTTGGGATCAATACAAAACATTTGAAGAACGTGGTGACGAATTTATTGCAGCAGTTCAAAATTT
ACATAAAGGGGAATAATTAA

Downstream 100 bases:

>100_bases
ATATAGGTAGTAAGATGAAAAAGAAGAAGGATGAAGAATTAACTCCGTGGGCCAAATATCAAAAAGAACATAATGCAAAT
AGTAGAAGCAGATTTAAGCG

Product: UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MRLMVSGGGTGGHIYPALALIKQVKQSEPDSQILYVGTSKGLESKIVPDSGIDFKTINIQGFKRSLSLENFKTIGLFLSS
VVKARKMVKEFKPDVVLGTGGYVSGAVVFAASMMGVPTVIHEQNSVVGVTNKFLSKFVKKIAISFEAAASQFPTKKVVLT
GNPRATEVAQIKPSGLSQFGLDDKVPTVLIFGGSRGAEKINQVTIDTLEELMERPYQTIFVTGRVHFERLTKDIDLAKYQ
GKIAILPYIANMPEILSNMEVIVGRAGATSLAEITSLGIPSILIPSPYVTNDHQTKNAMSLVNNDAAEIIKESDLTSEAL
INTLDTLMLDQKFRNVMAENAKKMGQPRAAENLYDVLKSVSK

Sequences:

>Translated_362_residues
MRLMVSGGGTGGHIYPALALIKQVKQSEPDSQILYVGTSKGLESKIVPDSGIDFKTINIQGFKRSLSLENFKTIGLFLSS
VVKARKMVKEFKPDVVLGTGGYVSGAVVFAASMMGVPTVIHEQNSVVGVTNKFLSKFVKKIAISFEAAASQFPTKKVVLT
GNPRATEVAQIKPSGLSQFGLDDKVPTVLIFGGSRGAEKINQVTIDTLEELMERPYQTIFVTGRVHFERLTKDIDLAKYQ
GKIAILPYIANMPEILSNMEVIVGRAGATSLAEITSLGIPSILIPSPYVTNDHQTKNAMSLVNNDAAEIIKESDLTSEAL
INTLDTLMLDQKFRNVMAENAKKMGQPRAAENLYDVLKSVSK
>Mature_362_residues
MRLMVSGGGTGGHIYPALALIKQVKQSEPDSQILYVGTSKGLESKIVPDSGIDFKTINIQGFKRSLSLENFKTIGLFLSS
VVKARKMVKEFKPDVVLGTGGYVSGAVVFAASMMGVPTVIHEQNSVVGVTNKFLSKFVKKIAISFEAAASQFPTKKVVLT
GNPRATEVAQIKPSGLSQFGLDDKVPTVLIFGGSRGAEKINQVTIDTLEELMERPYQTIFVTGRVHFERLTKDIDLAKYQ
GKIAILPYIANMPEILSNMEVIVGRAGATSLAEITSLGIPSILIPSPYVTNDHQTKNAMSLVNNDAAEIIKESDLTSEAL
INTLDTLMLDQKFRNVMAENAKKMGQPRAAENLYDVLKSVSK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=362, Percent_Identity=32.3204419889503, Blast_Score=172, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_PEDPA (Q03EY2)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804682.1
- ProteinModelPortal:   Q03EY2
- SMR:   Q03EY2
- STRING:   Q03EY2
- GeneID:   4417585
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1186
- NMPDR:   fig|278197.10.peg.1044
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   Q03EY2
- BioCyc:   PPEN278197:PEPE_1186-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39241; Mature: 39241

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLMVSGGGTGGHIYPALALIKQVKQSEPDSQILYVGTSKGLESKIVPDSGIDFKTINIQ
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEC
GFKRSLSLENFKTIGLFLSSVVKARKMVKEFKPDVVLGTGGYVSGAVVFAASMMGVPTVI
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCEEE
HEQNSVVGVTNKFLSKFVKKIAISFEAAASQFPTKKVVLTGNPRATEVAQIKPSGLSQFG
ECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCCCCC
LDDKVPTVLIFGGSRGAEKINQVTIDTLEELMERPYQTIFVTGRVHFERLTKDIDLAKYQ
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHC
GKIAILPYIANMPEILSNMEVIVGRAGATSLAEITSLGIPSILIPSPYVTNDHQTKNAMS
CCEEEEEHHCCCHHHHCCCCEEEECCCCHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHH
LVNNDAAEIIKESDLTSEALINTLDTLMLDQKFRNVMAENAKKMGQPRAAENLYDVLKSV
HHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SK
CC
>Mature Secondary Structure
MRLMVSGGGTGGHIYPALALIKQVKQSEPDSQILYVGTSKGLESKIVPDSGIDFKTINIQ
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEC
GFKRSLSLENFKTIGLFLSSVVKARKMVKEFKPDVVLGTGGYVSGAVVFAASMMGVPTVI
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCEEE
HEQNSVVGVTNKFLSKFVKKIAISFEAAASQFPTKKVVLTGNPRATEVAQIKPSGLSQFG
ECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCCCCC
LDDKVPTVLIFGGSRGAEKINQVTIDTLEELMERPYQTIFVTGRVHFERLTKDIDLAKYQ
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHC
GKIAILPYIANMPEILSNMEVIVGRAGATSLAEITSLGIPSILIPSPYVTNDHQTKNAMS
CCEEEEEHHCCCHHHHCCCCEEEECCCCHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHH
LVNNDAAEIIKESDLTSEALINTLDTLMLDQKFRNVMAENAKKMGQPRAAENLYDVLKSV
HHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA