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The map label for this gene is fruR [H]

Identifier: 116492927

GI number: 116492927

Start: 1165736

End: 1166485

Strand: Reverse

Name: fruR [H]

Synonym: PEPE_1166

Alternate gene names: 116492927

Gene position: 1166485-1165736 (Counterclockwise)

Preceding gene: 116492928

Following gene: 116492926

Centisome position: 63.66

GC content: 37.2

Gene sequence:

>750_bases
GTGCTTACAGAACTTCGAGAACGAAATATTTTACGTTTATTAAGAGAGAAACAAGTTATCAAAGTTGATGAAATTATGCA
TGCAAATCAATCATCAATTTCTACGGTTCGTCGAGATTTAAAAAAACTTGAAGCAGAAGGAAAGCTAGTCCGTGTTCATG
GTGGAGCTCAACTTGAAAATGGGCTTCAAACCGAAACGGATTTTCAAGTTAAATCGAAAATGAATCTATTAGAAAAAAAT
GAAATTGGGCGACAAGCTGCAGAACTGGTTCAAAGTGGAGAGATTATTTTTCTGGATGCCGGAACTTCCACTGCAACGAT
CATTCCATACTTGGCAGAAAGCGAGGGACTGTTAGTTGTAACCAATGGATTGACGATTGCTGGATTACTGTCAGATTTTG
ATATCAATGCGTATCTAGTTGGTGGCCAATTAAAAAATAAAACCCGGGCTTTGATTGGATCAGAGGTAACGGATCGGATT
CGAACATTTCAATTTGATCGATGTTTCATGGGAACCAATGGGGTATCCCAAGAATTAGGATTTACCACTCCAGATATTCA
AGAAGCCCAGATTAAGTCAGAAGTGATTAAAAGAAGTCGAAATGCTTATGTTTTAGCAGATAGCTCTAAGTTTAATAAGA
CTTCATTTGTACGTTTTGCAGAATTGCAAGATGCAACAATTATTGCCGACCATTGTCCAGAATGGCTCAAAGCAGAGGAA
AATATATATTATATGGAGGTTCAAAAATGA

Upstream 100 bases:

>100_bases
CTTTTTTTGATGTAAAATGAACGAAATTGAATTTTTTTGAATTAATTTGATTGATTTTGAACTAAAATGATGGTATATTC
TTCTATGGAGGTTGATGAAA

Downstream 100 bases:

>100_bases
TTTACACAGTTACACTTAACCCATCGATTGATTATGTAATCAGTCTGGATGAAATGAAAGTTGGCTTGGTCAATCGCTTG
AAGACATCAAGTAAATTTCC

Product: lactose transport regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MLTELRERNILRLLREKQVIKVDEIMHANQSSISTVRRDLKKLEAEGKLVRVHGGAQLENGLQTETDFQVKSKMNLLEKN
EIGRQAAELVQSGEIIFLDAGTSTATIIPYLAESEGLLVVTNGLTIAGLLSDFDINAYLVGGQLKNKTRALIGSEVTDRI
RTFQFDRCFMGTNGVSQELGFTTPDIQEAQIKSEVIKRSRNAYVLADSSKFNKTSFVRFAELQDATIIADHCPEWLKAEE
NIYYMEVQK

Sequences:

>Translated_249_residues
MLTELRERNILRLLREKQVIKVDEIMHANQSSISTVRRDLKKLEAEGKLVRVHGGAQLENGLQTETDFQVKSKMNLLEKN
EIGRQAAELVQSGEIIFLDAGTSTATIIPYLAESEGLLVVTNGLTIAGLLSDFDINAYLVGGQLKNKTRALIGSEVTDRI
RTFQFDRCFMGTNGVSQELGFTTPDIQEAQIKSEVIKRSRNAYVLADSSKFNKTSFVRFAELQDATIIADHCPEWLKAEE
NIYYMEVQK
>Mature_249_residues
MLTELRERNILRLLREKQVIKVDEIMHANQSSISTVRRDLKKLEAEGKLVRVHGGAQLENGLQTETDFQVKSKMNLLEKN
EIGRQAAELVQSGEIIFLDAGTSTATIIPYLAESEGLLVVTNGLTIAGLLSDFDINAYLVGGQLKNKTRALIGSEVTDRI
RTFQFDRCFMGTNGVSQELGFTTPDIQEAQIKSEVIKRSRNAYVLADSSKFNKTSFVRFAELQDATIIADHCPEWLKAEE
NIYYMEVQK

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI226510968, Length=237, Percent_Identity=32.0675105485232, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789519, Length=236, Percent_Identity=27.9661016949153, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1789829, Length=218, Percent_Identity=27.9816513761468, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789059, Length=212, Percent_Identity=29.2452830188679, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787540, Length=207, Percent_Identity=31.8840579710145, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1788069, Length=206, Percent_Identity=30.5825242718447, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87082344, Length=240, Percent_Identity=25.8333333333333, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790753, Length=229, Percent_Identity=27.0742358078603, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1789170, Length=229, Percent_Identity=26.2008733624454, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787063, Length=253, Percent_Identity=24.901185770751, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790635, Length=216, Percent_Identity=25, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27973; Mature: 27973

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTELRERNILRLLREKQVIKVDEIMHANQSSISTVRRDLKKLEAEGKLVRVHGGAQLEN
CCCCHHHHHHHHHHHHCCCEEHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHCC
GLQTETDFQVKSKMNLLEKNEIGRQAAELVQSGEIIFLDAGTSTATIIPYLAESEGLLVV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEEECCCCEEEE
TNGLTIAGLLSDFDINAYLVGGQLKNKTRALIGSEVTDRIRTFQFDRCFMGTNGVSQELG
ECCCEEEEEHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHEECCEEEECCCCCCHHCC
FTTPDIQEAQIKSEVIKRSRNAYVLADSSKFNKTSFVRFAELQDATIIADHCPEWLKAEE
CCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHEEEEECCCCCEEEHHCCHHHHCCCC
NIYYMEVQK
CEEEEEECC
>Mature Secondary Structure
MLTELRERNILRLLREKQVIKVDEIMHANQSSISTVRRDLKKLEAEGKLVRVHGGAQLEN
CCCCHHHHHHHHHHHHCCCEEHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHCC
GLQTETDFQVKSKMNLLEKNEIGRQAAELVQSGEIIFLDAGTSTATIIPYLAESEGLLVV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEEECCCCEEEE
TNGLTIAGLLSDFDINAYLVGGQLKNKTRALIGSEVTDRIRTFQFDRCFMGTNGVSQELG
ECCCEEEEEHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHEECCEEEECCCCCCHHCC
FTTPDIQEAQIKSEVIKRSRNAYVLADSSKFNKTSFVRFAELQDATIIADHCPEWLKAEE
CCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHEEEEECCCCCEEEHHCCHHHHCCCC
NIYYMEVQK
CEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]