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The map label for this gene is comEA [H]

Identifier: 116492912

GI number: 116492912

Start: 1151244

End: 1151951

Strand: Reverse

Name: comEA [H]

Synonym: PEPE_1151

Alternate gene names: 116492912

Gene position: 1151951-1151244 (Counterclockwise)

Preceding gene: 116492913

Following gene: 116492911

Centisome position: 62.87

GC content: 36.44

Gene sequence:

>708_bases
ATGTTGGAAGAAATTTGGGAAAAATATCAAAAACAAATTATAATAACAGGTATAACAGTCACAATAGTGGTCATGTTTTT
TTGTATTTTGGTAGGAGCGGGGCGTAATGATAGTACTGATAAGATGATTGGAAACAATCTGACTAGTTCGTCCAGTTCTA
TACAAAGCAGCTCAAACTCTGCAACGCCAATGGCGAGTGGACAAGATAAGGAGACTCACGCCCAGAGACTTGCTAGTTCT
AAAATAATGGTGGATGTTAAAGGAGCTGTGAAAAGCCCTGGAGTTTATGAAGTGAAGTCAGGAATGCGAATAATGGATGC
GATTGAAATTGCTGGTGGAATGACTAAATCAGCTGATCAAAGAAATATTAACCTTGCGACTCAATTGTCTGATCAACAAG
TAGTTTATGTACCGATTAAGGGTGAGATAAAAAATTCTGATCCGTCACAATTAAGTGCAGTTGGTTCATCGAGTATTTCA
AGTAGCAGCCCTTCCACAACCGATAGTTCAACTGAAAAAATAGTTAACATAAATACTGCCTCTAAAGCAGAATTGTTGAC
ATTGAATGGTGTAGGAGATAAAAAAGCTGAACAAATTATTAATTATCGTGAACAACAGGGCGAATTTAAATCCATTGAAG
ATTTAAAGCAAGTACAGGGGATTGGTGATAAAATTTTTGAAGGACTACAAGATGCAATTACTGTATAA

Upstream 100 bases:

>100_bases
AGAAGTATTATTAAAATCAAGACTAAAATGACTATTTAAAGGATTGGAAAATAAATTCCAATCTTTTTTTGTATCTTCTG
TTAGCTAAGGAGGTGCAAAA

Downstream 100 bases:

>100_bases
ATTAAGGATGGAAATGATATGGACAATAGAATTGATTGGGATCAATATTTTATGACACAGGCAACCCTGTTATCACTCAG
AAGTACGTGCACGCGGCTTT

Product: DNA uptake protein related DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MLEEIWEKYQKQIIITGITVTIVVMFFCILVGAGRNDSTDKMIGNNLTSSSSSIQSSSNSATPMASGQDKETHAQRLASS
KIMVDVKGAVKSPGVYEVKSGMRIMDAIEIAGGMTKSADQRNINLATQLSDQQVVYVPIKGEIKNSDPSQLSAVGSSSIS
SSSPSTTDSSTEKIVNINTASKAELLTLNGVGDKKAEQIINYREQQGEFKSIEDLKQVQGIGDKIFEGLQDAITV

Sequences:

>Translated_235_residues
MLEEIWEKYQKQIIITGITVTIVVMFFCILVGAGRNDSTDKMIGNNLTSSSSSIQSSSNSATPMASGQDKETHAQRLASS
KIMVDVKGAVKSPGVYEVKSGMRIMDAIEIAGGMTKSADQRNINLATQLSDQQVVYVPIKGEIKNSDPSQLSAVGSSSIS
SSSPSTTDSSTEKIVNINTASKAELLTLNGVGDKKAEQIINYREQQGEFKSIEDLKQVQGIGDKIFEGLQDAITV
>Mature_235_residues
MLEEIWEKYQKQIIITGITVTIVVMFFCILVGAGRNDSTDKMIGNNLTSSSSSIQSSSNSATPMASGQDKETHAQRLASS
KIMVDVKGAVKSPGVYEVKSGMRIMDAIEIAGGMTKSADQRNINLATQLSDQQVVYVPIKGEIKNSDPSQLSAVGSSSIS
SSSPSTTDSSTEKIVNINTASKAELLTLNGVGDKKAEQIINYREQQGEFKSIEDLKQVQGIGDKIFEGLQDAITV

Specific function: Needed for both DNA binding and transport. It is absolutely required for the uptake of transforming DNA but not for binding. Its role in binding may be indirect [H]

COG id: COG1555

COG function: function code L; DNA uptake protein and related DNA-binding proteins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HhH domains [H]

Homologues:

Organism=Escherichia coli, GI1786646, Length=54, Percent_Identity=55.5555555555556, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004787
- InterPro:   IPR004509
- InterPro:   IPR000445
- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR019554 [H]

Pfam domain/function: PF00633 HHH; PF10531 SLBB [H]

EC number: NA

Molecular weight: Translated: 25187; Mature: 25187

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEEIWEKYQKQIIITGITVTIVVMFFCILVGAGRNDSTDKMIGNNLTSSSSSIQSSSNS
CHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCHHHHCCCCC
ATPMASGQDKETHAQRLASSKIMVDVKGAVKSPGVYEVKSGMRIMDAIEIAGGMTKSADQ
CCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCEEHHCCCHHHHHHHHHCCCCCCCCC
RNINLATQLSDQQVVYVPIKGEIKNSDPSQLSAVGSSSISSSSPSTTDSSTEKIVNINTA
CCCEEEEECCCCEEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCC
SKAELLTLNGVGDKKAEQIINYREQQGEFKSIEDLKQVQGIGDKIFEGLQDAITV
CCEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLEEIWEKYQKQIIITGITVTIVVMFFCILVGAGRNDSTDKMIGNNLTSSSSSIQSSSNS
CHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCHHHHCCCCC
ATPMASGQDKETHAQRLASSKIMVDVKGAVKSPGVYEVKSGMRIMDAIEIAGGMTKSADQ
CCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCEEHHCCCHHHHHHHHHCCCCCCCCC
RNINLATQLSDQQVVYVPIKGEIKNSDPSQLSAVGSSSISSSSPSTTDSSTEKIVNINTA
CCCEEEEECCCCEEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCC
SKAELLTLNGVGDKKAEQIINYREQQGEFKSIEDLKQVQGIGDKIFEGLQDAITV
CCEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377; 7768800 [H]