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The map label for this gene is lspA [H]

Identifier: 116492704

GI number: 116492704

Start: 941392

End: 941844

Strand: Direct

Name: lspA [H]

Synonym: PEPE_0940

Alternate gene names: 116492704

Gene position: 941392-941844 (Clockwise)

Preceding gene: 116492703

Following gene: 116492705

Centisome position: 51.38

GC content: 32.67

Gene sequence:

>453_bases
ATGAAATGGTTTAGTTATATAGTTGGTTTATTACTTTTAGTAATTGATCAGCTGGTAAAAAGCGCTGTTAGTAATCAGAT
TGCTTTAGGAACTGTTAAAAGTTTTATTCCAGGAGTATTGTCCTTAACCAATTTACGTAATGATGGTGCCGCTTGGAGTA
TTTTATCAGGAAATCAGATATTTTTTTATCTAATCACCGTAGTAGCTTTAGTCGTATTAATCTATTTACTAGTTACACAG
CGCCAGCACTTATTATATCAATGGGGATTAACCCTCATGATTACAGGAACCTTGGGTAATTTTATTGACCGCATTCGTTT
AAAATACGTTGTTGATATGTTTCAAATTGACTTTTTCAATTTTCCAATTTTTAACATTGCTGATATGTGCTTAACTTTTG
GTGTCATCATATTATTCATTGCCATTATTCGCGACGAAAGAATTGAGGGGTAG

Upstream 100 bases:

>100_bases
GTGCTTACTATGCCAGGACTTCCCAAGCATCCTGCCGCATTAGATATCGACATCGATAGTAAAGGAGAAATTACCGGATT
ATTCTAGTAATTAAAGTTTT

Downstream 100 bases:

>100_bases
TTAGAGTTTATGGAACAATTTTCATTTGTGGTTTCAGATCAAGAAAGTGGGCGTTTGGATAAAGTAGTTACCAATCATTA
TCCAGATTTAACACGGTCAA

Product: signal peptidase II

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MKWFSYIVGLLLLVIDQLVKSAVSNQIALGTVKSFIPGVLSLTNLRNDGAAWSILSGNQIFFYLITVVALVVLIYLLVTQ
RQHLLYQWGLTLMITGTLGNFIDRIRLKYVVDMFQIDFFNFPIFNIADMCLTFGVIILFIAIIRDERIEG

Sequences:

>Translated_150_residues
MKWFSYIVGLLLLVIDQLVKSAVSNQIALGTVKSFIPGVLSLTNLRNDGAAWSILSGNQIFFYLITVVALVVLIYLLVTQ
RQHLLYQWGLTLMITGTLGNFIDRIRLKYVVDMFQIDFFNFPIFNIADMCLTFGVIILFIAIIRDERIEG
>Mature_150_residues
MKWFSYIVGLLLLVIDQLVKSAVSNQIALGTVKSFIPGVLSLTNLRNDGAAWSILSGNQIFFYLITVVALVVLIYLLVTQ
RQHLLYQWGLTLMITGTLGNFIDRIRLKYVVDMFQIDFFNFPIFNIADMCLTFGVIILFIAIIRDERIEG

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 17068; Mature: 17068

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWFSYIVGLLLLVIDQLVKSAVSNQIALGTVKSFIPGVLSLTNLRNDGAAWSILSGNQI
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHH
FFYLITVVALVVLIYLLVTQRQHLLYQWGLTLMITGTLGNFIDRIRLKYVVDMFQIDFFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHC
FPIFNIADMCLTFGVIILFIAIIRDERIEG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKWFSYIVGLLLLVIDQLVKSAVSNQIALGTVKSFIPGVLSLTNLRNDGAAWSILSGNQI
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHH
FFYLITVVALVVLIYLLVTQRQHLLYQWGLTLMITGTLGNFIDRIRLKYVVDMFQIDFFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHC
FPIFNIADMCLTFGVIILFIAIIRDERIEG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12566566 [H]