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The map label for this gene is frr

Identifier: 116492646

GI number: 116492646

Start: 879001

End: 879561

Strand: Direct

Name: frr

Synonym: PEPE_0880

Alternate gene names: 116492646

Gene position: 879001-879561 (Clockwise)

Preceding gene: 116492645

Following gene: 116492647

Centisome position: 47.97

GC content: 36.54

Gene sequence:

>561_bases
ATGGCAAAAAATGAGATAATCCAAAAAGCTGAAGAAAAAATGCAAAAGGCACAGAATGTTTTAGAACGTGATCTAGGTTC
AATCCGTGCTGGCCGTGCTAATGCTTCATTACTTGATAAAGTCTCAGTGGATTATTATGGAGCTCCAACTCCACTTAATC
AAATGGCTTCAATTACCATTCCGGAACCACGAGTATTGTTAGTTACTCCTTATGATAAGAGCGTATTGAACGACATTGAA
CAAGCTATTTTAATGTCAGATCTAGGGATTAATCCTGCTAATGATGGCTCAGCAATTCGTTTAGTAGTTCCTCAATTAAC
TGAAGAAACCCGTAAAGATTTAGCCAAGAATGTTAAAGCAGAAGGCGAAAAAGCTAAAGTAGCAGTTCGTAATATTCGTC
GTGATGCAATGGACACTTTGAAAAAGGCTAATAAAAATGGCGACTACAATGATGATGAATTCCATGATTTAGAAAAACAA
ACTCAAGATAGTACGGATAAAGCAATTAAAGTTGTAGACGAAATCGTAGCTAATAAGGAAAAAGAAGTCCTTGAAGGCTA
G

Upstream 100 bases:

>100_bases
ATAATATTCCATTAGTTGTTTTCAACTTAAACCAAGCAGGTAACATTAAAAAGGTTGTTGCAGGTGAAAATATTGGAACA
ACGGTTAGAGGAGAAGAATA

Downstream 100 bases:

>100_bases
TATTAACTTTTGATAAAGCACCCCAAGAATTGTAGTGAAAACTCAACTTTTGGGGTGCTTTACTGGTTATTGAAAAATTC
CAACTTCAACCAAAAAGTAT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MAKNEIIQKAEEKMQKAQNVLERDLGSIRAGRANASLLDKVSVDYYGAPTPLNQMASITIPEPRVLLVTPYDKSVLNDIE
QAILMSDLGINPANDGSAIRLVVPQLTEETRKDLAKNVKAEGEKAKVAVRNIRRDAMDTLKKANKNGDYNDDEFHDLEKQ
TQDSTDKAIKVVDEIVANKEKEVLEG

Sequences:

>Translated_186_residues
MAKNEIIQKAEEKMQKAQNVLERDLGSIRAGRANASLLDKVSVDYYGAPTPLNQMASITIPEPRVLLVTPYDKSVLNDIE
QAILMSDLGINPANDGSAIRLVVPQLTEETRKDLAKNVKAEGEKAKVAVRNIRRDAMDTLKKANKNGDYNDDEFHDLEKQ
TQDSTDKAIKVVDEIVANKEKEVLEG
>Mature_185_residues
AKNEIIQKAEEKMQKAQNVLERDLGSIRAGRANASLLDKVSVDYYGAPTPLNQMASITIPEPRVLLVTPYDKSVLNDIEQ
AILMSDLGINPANDGSAIRLVVPQLTEETRKDLAKNVKAEGEKAKVAVRNIRRDAMDTLKKANKNGDYNDDEFHDLEKQT
QDSTDKAIKVVDEIVANKEKEVLEG

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=180, Percent_Identity=28.8888888888889, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI291042689, Length=149, Percent_Identity=32.2147651006711, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1786368, Length=182, Percent_Identity=43.956043956044, Blast_Score=154, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24661488, Length=173, Percent_Identity=27.7456647398844, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_PEDPA (Q03FT3)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804381.1
- ProteinModelPortal:   Q03FT3
- SMR:   Q03FT3
- STRING:   Q03FT3
- GeneID:   4417840
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_0880
- NMPDR:   fig|278197.10.peg.782
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- BioCyc:   PPEN278197:PEPE_0880-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20631; Mature: 20499

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKNEIIQKAEEKMQKAQNVLERDLGSIRAGRANASLLDKVSVDYYGAPTPLNQMASITI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHCEEEC
PEPRVLLVTPYDKSVLNDIEQAILMSDLGINPANDGSAIRLVVPQLTEETRKDLAKNVKA
CCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHC
EGEKAKVAVRNIRRDAMDTLKKANKNGDYNDDEFHDLEKQTQDSTDKAIKVVDEIVANKE
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCH
KEVLEG
HHHHCC
>Mature Secondary Structure 
AKNEIIQKAEEKMQKAQNVLERDLGSIRAGRANASLLDKVSVDYYGAPTPLNQMASITI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHCEEEC
PEPRVLLVTPYDKSVLNDIEQAILMSDLGINPANDGSAIRLVVPQLTEETRKDLAKNVKA
CCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHC
EGEKAKVAVRNIRRDAMDTLKKANKNGDYNDDEFHDLEKQTQDSTDKAIKVVDEIVANKE
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCH
KEVLEG
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA