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The map label for this gene is tsf

Identifier: 116492644

GI number: 116492644

Start: 877244

End: 878122

Strand: Direct

Name: tsf

Synonym: PEPE_0878

Alternate gene names: 116492644

Gene position: 877244-878122 (Clockwise)

Preceding gene: 116492643

Following gene: 116492645

Centisome position: 47.87

GC content: 39.48

Gene sequence:

>879_bases
ATGGCAAGTATTTCAGCTAAATTAGTAAAAGAATTACGCGATAAAATCGGTGTTGGTATGATGGACGCTAAAAAAGCACT
TGTTGCTACAGAAGGTGACATGGACAAAGCAGTTGATTTTCTCCGTGAAAAAGGTATTGCAAAGGCTGCTAAGAAGAGTG
ACCGTGTTGCTGCTGAAGGTCTTGCAGATGTTGAAATGCATGACAACACAGCTGCAATTGTAGAAGTTAATTCAGAAACT
GACTTTGTTGCATCAAACGATCGTTTCATCGACTTAGTTAAGGAAATTGCTTCACAAGTTGCACTTGAAAAACCTGCAGA
TGTTGATGCTGCTCTTAAATTGAAGTCACCAAAGGGTACTTTGAATGATGATATCATCGAAGCAACTCAAGTAATTGGTG
AAAAGATTTCTCTTCGTCGCTTTGCTACTTTAGAAAAGGGTGAAAACGAACATTTCGGTTCATATCTTCACATGGGTGGT
AAAATTGCAGCGCTTGTATTGCTTGAAGGTGCTGATGAAGAAACTGCTAAAGACGTTGCTATGCACGTTGCAGCTATCAA
CCCTAAGTATGTTAACCGTGACCAAGTACCTGCTGAGGTATTGGACCACGAACGTGAAGTACTTAGCAAAGAAGCTGAAG
GTGAAGGCAAACCAGCTAACATCATCGAAAAGATGGTTACTGGTCGTTTGAACAAGTTCTTGGCTGAAATTAGTTTAGAT
GATCAAGAATATGTTAAAGATCCTGACCAAACAGTTGCTAAATATGTTGCTTCAAAGGGTGGTAAAGTTAAGTCATTTAT
CCGCTTTGAAGTTGGTGAAGGTATCGAAAAACAAACTGTTGACTTTGCTGAAGAAGTTCGTAAGGAAATGGGCCAATAA

Upstream 100 bases:

>100_bases
TCGTGATTTGAGACCTTTTAGGCCTGAGATTACGCGCGGCCTTTTTTTACGGAATCACAAATTGGTATTAGTAATATAAA
AAGCTAAGGGGGCCATAAAA

Downstream 100 bases:

>100_bases
AACCCAGAGTTTTTGGATATTTAAAAAGCGAATTAATATGAGTTTAGCTCAATTAATTCGCTTTTTTGTAGGATTTTACA
CGTAATAACAGTGTGGTTTG

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MASISAKLVKELRDKIGVGMMDAKKALVATEGDMDKAVDFLREKGIAKAAKKSDRVAAEGLADVEMHDNTAAIVEVNSET
DFVASNDRFIDLVKEIASQVALEKPADVDAALKLKSPKGTLNDDIIEATQVIGEKISLRRFATLEKGENEHFGSYLHMGG
KIAALVLLEGADEETAKDVAMHVAAINPKYVNRDQVPAEVLDHEREVLSKEAEGEGKPANIIEKMVTGRLNKFLAEISLD
DQEYVKDPDQTVAKYVASKGGKVKSFIRFEVGEGIEKQTVDFAEEVRKEMGQ

Sequences:

>Translated_292_residues
MASISAKLVKELRDKIGVGMMDAKKALVATEGDMDKAVDFLREKGIAKAAKKSDRVAAEGLADVEMHDNTAAIVEVNSET
DFVASNDRFIDLVKEIASQVALEKPADVDAALKLKSPKGTLNDDIIEATQVIGEKISLRRFATLEKGENEHFGSYLHMGG
KIAALVLLEGADEETAKDVAMHVAAINPKYVNRDQVPAEVLDHEREVLSKEAEGEGKPANIIEKMVTGRLNKFLAEISLD
DQEYVKDPDQTVAKYVASKGGKVKSFIRFEVGEGIEKQTVDFAEEVRKEMGQ
>Mature_291_residues
ASISAKLVKELRDKIGVGMMDAKKALVATEGDMDKAVDFLREKGIAKAAKKSDRVAAEGLADVEMHDNTAAIVEVNSETD
FVASNDRFIDLVKEIASQVALEKPADVDAALKLKSPKGTLNDDIIEATQVIGEKISLRRFATLEKGENEHFGSYLHMGGK
IAALVLLEGADEETAKDVAMHVAAINPKYVNRDQVPAEVLDHEREVLSKEAEGEGKPANIIEKMVTGRLNKFLAEISLDD
QEYVKDPDQTVAKYVASKGGKVKSFIRFEVGEGIEKQTVDFAEEVRKEMGQ

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=305, Percent_Identity=28.8524590163934, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI291084500, Length=326, Percent_Identity=27.9141104294479, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI291084498, Length=101, Percent_Identity=41.5841584158416, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI291084502, Length=101, Percent_Identity=41.5841584158416, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1786366, Length=286, Percent_Identity=43.006993006993, Blast_Score=207, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI17561440, Length=300, Percent_Identity=28.6666666666667, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI19921466, Length=303, Percent_Identity=28.0528052805281, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_PEDPA (Q03FT5)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804379.1
- ProteinModelPortal:   Q03FT5
- SMR:   Q03FT5
- STRING:   Q03FT5
- GeneID:   4417838
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_0878
- NMPDR:   fig|278197.10.peg.780
- eggNOG:   COG0264
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- PhylomeDB:   Q03FT5
- ProtClustDB:   PRK09377
- BioCyc:   PPEN278197:PEPE_0878-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 31873; Mature: 31741

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASISAKLVKELRDKIGVGMMDAKKALVATEGDMDKAVDFLREKGIAKAAKKSDRVAAEG
CCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
LADVEMHDNTAAIVEVNSETDFVASNDRFIDLVKEIASQVALEKPADVDAALKLKSPKGT
CCCEEECCCCEEEEEECCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCC
LNDDIIEATQVIGEKISLRRFATLEKGENEHFGSYLHMGGKIAALVLLEGADEETAKDVA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEEEECCCHHHHHHHH
MHVAAINPKYVNRDQVPAEVLDHEREVLSKEAEGEGKPANIIEKMVTGRLNKFLAEISLD
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
DQEYVKDPDQTVAKYVASKGGKVKSFIRFEVGEGIEKQTVDFAEEVRKEMGQ
CHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASISAKLVKELRDKIGVGMMDAKKALVATEGDMDKAVDFLREKGIAKAAKKSDRVAAEG
CCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
LADVEMHDNTAAIVEVNSETDFVASNDRFIDLVKEIASQVALEKPADVDAALKLKSPKGT
CCCEEECCCCEEEEEECCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCC
LNDDIIEATQVIGEKISLRRFATLEKGENEHFGSYLHMGGKIAALVLLEGADEETAKDVA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEEEECCCHHHHHHHH
MHVAAINPKYVNRDQVPAEVLDHEREVLSKEAEGEGKPANIIEKMVTGRLNKFLAEISLD
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
DQEYVKDPDQTVAKYVASKGGKVKSFIRFEVGEGIEKQTVDFAEEVRKEMGQ
CHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA