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The map label for this gene is fabH [H]

Identifier: 116492621

GI number: 116492621

Start: 859471

End: 860430

Strand: Direct

Name: fabH [H]

Synonym: PEPE_0855

Alternate gene names: 116492621

Gene position: 859471-860430 (Clockwise)

Preceding gene: 116492620

Following gene: 116492622

Centisome position: 46.9

GC content: 39.9

Gene sequence:

>960_bases
ATGGGATTGAGAATAATTGATTCAGCACTATCTACTCCTAAAAAAGTCGTTACTAACGATGATTTAACTAAAATACTGGA
TACGTCAGATGAATGGATTTCAAAAAGAACGGGAATCAAGCAACGCTATCAAGCCGTTGAAGAAACTACTTCTTCAATGG
CGATAGAAGTCGCTAAACAGCTCTTAGAGAAATCTAAAACGGATCCAAGTGGAATTGATTTAATTGTCGTGGCAACGATG
TCACCGGACTATATGTCGCCATCTGTTGCAGCTATAGTACAAGGAAGCATTGGTGCAACCAATGCAATGGCTTTTGACAT
TAGTGCCGCATGTAGCGGTTTTGTGTACGGCATGAGCATTGTTAATAACATGCTTCATGGAGGGAAGTTTAAGAAAGCGA
TCTTAATTGGTGCGGAAAAACTAACCCGGTTGCTAGATTGGACGGACCGTAGTACAGCCGTTTTGTTCGGTGACGCAGCA
GCTGGTATTTTGGCTGAAAATGATTCTTCGAACTCTTCATATTTAATCAACGAAAAATTGAATACATATGGGAATATGGG
CCAATATTTAACCGCTGGAAACGTAGCAGCCTTAGATGACCCAGCACAATCGTATTTCTTCCAAATGAACGGACGTAAAG
TTTATGAATTTGCCACTAAACGAGTTCCGGAATCAATTTTGACGGTTCTTCGTGAAGCGAACATTGATCCTAGTGAGGTA
AAGTATTTCTTACTTCATCAAGCAAATGAACGTATTATTAAAAGCGTTGCGAAAAAACTAGATTTATCAATGGATAAATT
TCCAGTCAACATTGATCGCTTTGGTAATACTGCAGCAGCCAGTGAACCCGTCTTGTTAGCAGAAATGTTAGCAGATGGAA
AAATTAATCGCGGTGACATTATCGTCTTTAGCGGCTTTGGCGGGGGCTTAACCGTCGGAACAAATGTTATCAAATATTAA

Upstream 100 bases:

>100_bases
GAAACATTTGCAATGGTCGGTGATAAAAAAGTTTGCCAAGCAGAACTAACATTCATTGTTGGAGCAACTGATAAGAAAGA
TAAATAGTCGGTGAATTGCA

Downstream 100 bases:

>100_bases
AAAAATAAATTAAATTATATTCTCGGAGGAATAATATTATGACTAAAGAAGAAGTATTCACAAAGGTACAAGCAGTAATC
GCAGAACAATTGGAAAAAGA

Product: 3-oxoacyl-[acyl-carrier-protein] synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MGLRIIDSALSTPKKVVTNDDLTKILDTSDEWISKRTGIKQRYQAVEETTSSMAIEVAKQLLEKSKTDPSGIDLIVVATM
SPDYMSPSVAAIVQGSIGATNAMAFDISAACSGFVYGMSIVNNMLHGGKFKKAILIGAEKLTRLLDWTDRSTAVLFGDAA
AGILAENDSSNSSYLINEKLNTYGNMGQYLTAGNVAALDDPAQSYFFQMNGRKVYEFATKRVPESILTVLREANIDPSEV
KYFLLHQANERIIKSVAKKLDLSMDKFPVNIDRFGNTAAASEPVLLAEMLADGKINRGDIIVFSGFGGGLTVGTNVIKY

Sequences:

>Translated_319_residues
MGLRIIDSALSTPKKVVTNDDLTKILDTSDEWISKRTGIKQRYQAVEETTSSMAIEVAKQLLEKSKTDPSGIDLIVVATM
SPDYMSPSVAAIVQGSIGATNAMAFDISAACSGFVYGMSIVNNMLHGGKFKKAILIGAEKLTRLLDWTDRSTAVLFGDAA
AGILAENDSSNSSYLINEKLNTYGNMGQYLTAGNVAALDDPAQSYFFQMNGRKVYEFATKRVPESILTVLREANIDPSEV
KYFLLHQANERIIKSVAKKLDLSMDKFPVNIDRFGNTAAASEPVLLAEMLADGKINRGDIIVFSGFGGGLTVGTNVIKY
>Mature_318_residues
GLRIIDSALSTPKKVVTNDDLTKILDTSDEWISKRTGIKQRYQAVEETTSSMAIEVAKQLLEKSKTDPSGIDLIVVATMS
PDYMSPSVAAIVQGSIGATNAMAFDISAACSGFVYGMSIVNNMLHGGKFKKAILIGAEKLTRLLDWTDRSTAVLFGDAAA
GILAENDSSNSSYLINEKLNTYGNMGQYLTAGNVAALDDPAQSYFFQMNGRKVYEFATKRVPESILTVLREANIDPSEVK
YFLLHQANERIIKSVAKKLDLSMDKFPVNIDRFGNTAAASEPVLLAEMLADGKINRGDIIVFSGFGGGLTVGTNVIKY

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=321, Percent_Identity=38.9408099688474, Blast_Score=229, Evalue=3e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 34535; Mature: 34404

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLRIIDSALSTPKKVVTNDDLTKILDTSDEWISKRTGIKQRYQAVEETTSSMAIEVAKQ
CCCEEEHHHHCCCHHHHCCCHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LLEKSKTDPSGIDLIVVATMSPDYMSPSVAAIVQGSIGATNAMAFDISAACSGFVYGMSI
HHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHEECCCCCCCEEEEEHHHHHHHHHHHHHH
VNNMLHGGKFKKAILIGAEKLTRLLDWTDRSTAVLFGDAAAGILAENDSSNSSYLINEKL
HHHHHCCCCHHHHEEECHHHHHHHHCCCCCCCEEEEECCCCCEEECCCCCCCCEEEECHH
NTYGNMGQYLTAGNVAALDDPAQSYFFQMNGRKVYEFATKRVPESILTVLREANIDPSEV
HHHCCCCCEEECCCEEECCCHHHHHEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCHHHH
KYFLLHQANERIIKSVAKKLDLSMDKFPVNIDRFGNTAAASEPVLLAEMLADGKINRGDI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHCCCCCCCCE
IVFSGFGGGLTVGTNVIKY
EEEECCCCCEECCCHHHCC
>Mature Secondary Structure 
GLRIIDSALSTPKKVVTNDDLTKILDTSDEWISKRTGIKQRYQAVEETTSSMAIEVAKQ
CCEEEHHHHCCCHHHHCCCHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LLEKSKTDPSGIDLIVVATMSPDYMSPSVAAIVQGSIGATNAMAFDISAACSGFVYGMSI
HHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHEECCCCCCCEEEEEHHHHHHHHHHHHHH
VNNMLHGGKFKKAILIGAEKLTRLLDWTDRSTAVLFGDAAAGILAENDSSNSSYLINEKL
HHHHHCCCCHHHHEEECHHHHHHHHCCCCCCCEEEEECCCCCEEECCCCCCCCEEEECHH
NTYGNMGQYLTAGNVAALDDPAQSYFFQMNGRKVYEFATKRVPESILTVLREANIDPSEV
HHHCCCCCEEECCCEEECCCHHHHHEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCHHHH
KYFLLHQANERIIKSVAKKLDLSMDKFPVNIDRFGNTAAASEPVLLAEMLADGKINRGDI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHCCCCCCCCE
IVFSGFGGGLTVGTNVIKY
EEEECCCCCEECCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA