Click here to switch to the map view.

The map label for this gene is fabZ

Identifier: 116492620

GI number: 116492620

Start: 859008

End: 859457

Strand: Direct

Name: fabZ

Synonym: PEPE_0854

Alternate gene names: 116492620

Gene position: 859008-859457 (Clockwise)

Preceding gene: 116492618

Following gene: 116492621

Centisome position: 46.88

GC content: 35.56

Gene sequence:

>450_bases
TTGAGTATTTTAAATACAACAGAGATTATGGAACTAATTCCTAATCGTTACCCCATTCTATTCATGGACTATGTTGATGA
ATTAGAACCTGGAAAATCAATCGTGGCGACTAAAAACGTCACAATCAACGAAGAATTTTTCCAAGGACATTTTCCTGGTA
ACCCGGTTATGCCTGGAGTTTTAATCATTGAATCTCTAGCACAAGCTGCATCAATTCTAATTCTAAAATCAGAAGAATTT
GCAGGTAAGACAGCATATCTAGGTGCCATTAATGGTGCTAAATTTAGACAGATCGTCCGTCCTGGTGATGTTTTAAAACT
TCATGTTGAAATGATCAAGAAAAAGAGAAACATGGGTGTTGTTGAAACATTTGCAATGGTCGGTGATAAAAAAGTTTGCC
AAGCAGAACTAACATTCATTGTTGGAGCAACTGATAAGAAAGATAAATAG

Upstream 100 bases:

>100_bases
TATTTTTTTTGATTGCGAAAAGACTAAATACCGATTATTCTTTTTATTATTCCAATAACGTTGGAGTACAGATCATTAAT
TACTAGGAGGAAATAATAAT

Downstream 100 bases:

>100_bases
TCGGTGAATTGCAATGGGATTGAGAATAATTGATTCAGCACTATCTACTCCTAAAAAAGTCGTTACTAACGATGATTTAA
CTAAAATACTGGATACGTCA

Product: 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MSILNTTEIMELIPNRYPILFMDYVDELEPGKSIVATKNVTINEEFFQGHFPGNPVMPGVLIIESLAQAASILILKSEEF
AGKTAYLGAINGAKFRQIVRPGDVLKLHVEMIKKKRNMGVVETFAMVGDKKVCQAELTFIVGATDKKDK

Sequences:

>Translated_149_residues
MSILNTTEIMELIPNRYPILFMDYVDELEPGKSIVATKNVTINEEFFQGHFPGNPVMPGVLIIESLAQAASILILKSEEF
AGKTAYLGAINGAKFRQIVRPGDVLKLHVEMIKKKRNMGVVETFAMVGDKKVCQAELTFIVGATDKKDK
>Mature_148_residues
SILNTTEIMELIPNRYPILFMDYVDELEPGKSIVATKNVTINEEFFQGHFPGNPVMPGVLIIESLAQAASILILKSEEFA
GKTAYLGAINGAKFRQIVRPGDVLKLHVEMIKKKRNMGVVETFAMVGDKKVCQAELTFIVGATDKKDK

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=136, Percent_Identity=43.3823529411765, Blast_Score=119, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_PEDPA (Q03FV9)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804355.1
- ProteinModelPortal:   Q03FV9
- SMR:   Q03FV9
- STRING:   Q03FV9
- GeneID:   4417971
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_0854
- NMPDR:   fig|278197.10.peg.758
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   AELTFIV
- ProtClustDB:   CLSK912452
- BioCyc:   PPEN278197:PEPE_0854-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 16516; Mature: 16384

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: ACT_SITE 50-50

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILNTTEIMELIPNRYPILFMDYVDELEPGKSIVATKNVTINEEFFQGHFPGNPVMPGV
CCCCCHHHHHHHCCCCCCEEEEEHHHCCCCCCEEEEECCCEECHHHHCCCCCCCCCCCHH
LIIESLAQAASILILKSEEFAGKTAYLGAINGAKFRQIVRPGDVLKLHVEMIKKKRNMGV
HHHHHHHHHHHEEEEECCCCCCCEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCH
VETFAMVGDKKVCQAELTFIVGATDKKDK
HHHHHHHCCCHHHEEEEEEEEECCCCCCC
>Mature Secondary Structure 
SILNTTEIMELIPNRYPILFMDYVDELEPGKSIVATKNVTINEEFFQGHFPGNPVMPGV
CCCCHHHHHHHCCCCCCEEEEEHHHCCCCCCEEEEECCCEECHHHHCCCCCCCCCCCHH
LIIESLAQAASILILKSEEFAGKTAYLGAINGAKFRQIVRPGDVLKLHVEMIKKKRNMGV
HHHHHHHHHHHEEEEECCCCCCCEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCH
VETFAMVGDKKVCQAELTFIVGATDKKDK
HHHHHHHCCCHHHEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA