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The map label for this gene is xseA

Identifier: 116492585

GI number: 116492585

Start: 824102

End: 825445

Strand: Direct

Name: xseA

Synonym: PEPE_0818

Alternate gene names: 116492585

Gene position: 824102-825445 (Clockwise)

Preceding gene: 116492584

Following gene: 116492586

Centisome position: 44.97

GC content: 37.35

Gene sequence:

>1344_bases
ATGCAAGAAGATAAGTATTTAACGGTCAGTGCACTAACCAATTATATTAAACGAAAATTTGATGCTGATCCGTATTTACA
TCGCGTTTATTTAGTGGGGGAAATTTCAAACTTTCGCTTAAGAACTAACAGTCACCAATATTTTAGTTTGAAGGACGAAA
ACGCGAAGATTAGTGCGATCATGTTTAAATCTGCATTTGCGAAGGTTAAGTTTCAACCTGAAGAAGGCATGCGAGTGATT
GTGAGTGGGCGAATTAGTTTATACCCAGGAAATGGTAGTTACCAAATTTATGTCGATAGTATGCAACCGGATGGTGTAGG
AGCTTTATATCAAGCATATGAACAGTTAAAGATAAAATTATCCCAAGAAGGTTTATTTGAAGCCCCTAAGCTACCAATTC
CTAAGTATCCCCGTAAGATTGCGATTGTGACTAGCCCTTCTGGGGCCGTGATTAGAGATATTATCACGACGGTGAGCCGT
CGTTATCCGATTGTTCAACTGGTTTTATTTCCAGCTTTAGTTCAAGGTAATGAGGCAGCCAATAGTATAGCTGCACAAAT
AAAGATGATTAATACGTTGGATGATTTTGATACCATCATTATTGGCCGAGGTGGGGGCTCAATTGAAGATTTATGGCCAT
TCAATGAAGAAGTAGTTGCTCGAGCAATCTTTGCAAGTAAGTTACCGGTTATTTCCTCTGTCGGACATGAAACAGATACG
ACAATCGCCGATTTAGTTGCAGATATGCGGGCAGCAACTCCAACGGCCGCCGCTGAACTAGCTACGCCTGTACTGACCGA
TATCTTAGAAGAGCTTCAAAAACTCCAGCTACAAACTATTGTGGCGTTTAGAAATATTTTAAAAATGCGTAGCCAGCAGG
TTCAACATTTACAACAATCGTATATTTTTCAAGAACCTCAACGTTTATATGAAGGTTATGTGCAAAATGTTGATATTTTA
ACGGAAAAGTTGATTTCGTTGGAGAAACAACAAATTACTACAGCTGAGGGATCATTTAAAACTCTAAATTCAAGATTGTT
AGCCAATACTCCAGCTAGTAGAATTAAAATGGCAAAACAAAATGTTGAGCATCTACGACAGATGACCAATAATAATATAA
CTAATCGTTTTTCAAAGTATGCGAATGATTTGAATTCGCTGATTGGATCTTTAGATACTCTGAGCCCCCTCAAGATAATG
AGTAGAGGTTATACTTATGTAACTAGAGATACGAAGGTCGTTAAATCGATTGAGGATTTATCAATTGACGATAAAATTCA
ACTGAATTTTAGTGATGGTAGTGCAAATGCAGTAATTAAAACAATTAACAGCGAGGATAAATAA

Upstream 100 bases:

>100_bases
ACATGTTTCATACATCACCCCCGTTCCTAAGGGCGTTGGTCCGATGACAATATCAATGTTAATGAAACAAACGGTGAATT
TAACTAAATGGAGTATTTAA

Downstream 100 bases:

>100_bases
TGGCTGAAGAAAAAACATTTGAAGAAAATTTACAAGAATTACAACAAGTTGTTTCCAATTTAGAACAAGGTGATATTCCA
TTGGAAAAAGCTTTGACAGA

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MQEDKYLTVSALTNYIKRKFDADPYLHRVYLVGEISNFRLRTNSHQYFSLKDENAKISAIMFKSAFAKVKFQPEEGMRVI
VSGRISLYPGNGSYQIYVDSMQPDGVGALYQAYEQLKIKLSQEGLFEAPKLPIPKYPRKIAIVTSPSGAVIRDIITTVSR
RYPIVQLVLFPALVQGNEAANSIAAQIKMINTLDDFDTIIIGRGGGSIEDLWPFNEEVVARAIFASKLPVISSVGHETDT
TIADLVADMRAATPTAAAELATPVLTDILEELQKLQLQTIVAFRNILKMRSQQVQHLQQSYIFQEPQRLYEGYVQNVDIL
TEKLISLEKQQITTAEGSFKTLNSRLLANTPASRIKMAKQNVEHLRQMTNNNITNRFSKYANDLNSLIGSLDTLSPLKIM
SRGYTYVTRDTKVVKSIEDLSIDDKIQLNFSDGSANAVIKTINSEDK

Sequences:

>Translated_447_residues
MQEDKYLTVSALTNYIKRKFDADPYLHRVYLVGEISNFRLRTNSHQYFSLKDENAKISAIMFKSAFAKVKFQPEEGMRVI
VSGRISLYPGNGSYQIYVDSMQPDGVGALYQAYEQLKIKLSQEGLFEAPKLPIPKYPRKIAIVTSPSGAVIRDIITTVSR
RYPIVQLVLFPALVQGNEAANSIAAQIKMINTLDDFDTIIIGRGGGSIEDLWPFNEEVVARAIFASKLPVISSVGHETDT
TIADLVADMRAATPTAAAELATPVLTDILEELQKLQLQTIVAFRNILKMRSQQVQHLQQSYIFQEPQRLYEGYVQNVDIL
TEKLISLEKQQITTAEGSFKTLNSRLLANTPASRIKMAKQNVEHLRQMTNNNITNRFSKYANDLNSLIGSLDTLSPLKIM
SRGYTYVTRDTKVVKSIEDLSIDDKIQLNFSDGSANAVIKTINSEDK
>Mature_447_residues
MQEDKYLTVSALTNYIKRKFDADPYLHRVYLVGEISNFRLRTNSHQYFSLKDENAKISAIMFKSAFAKVKFQPEEGMRVI
VSGRISLYPGNGSYQIYVDSMQPDGVGALYQAYEQLKIKLSQEGLFEAPKLPIPKYPRKIAIVTSPSGAVIRDIITTVSR
RYPIVQLVLFPALVQGNEAANSIAAQIKMINTLDDFDTIIIGRGGGSIEDLWPFNEEVVARAIFASKLPVISSVGHETDT
TIADLVADMRAATPTAAAELATPVLTDILEELQKLQLQTIVAFRNILKMRSQQVQHLQQSYIFQEPQRLYEGYVQNVDIL
TEKLISLEKQQITTAEGSFKTLNSRLLANTPASRIKMAKQNVEHLRQMTNNNITNRFSKYANDLNSLIGSLDTLSPLKIM
SRGYTYVTRDTKVVKSIEDLSIDDKIQLNFSDGSANAVIKTINSEDK

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=443, Percent_Identity=34.7629796839729, Blast_Score=280, Evalue=2e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_PEDPA (Q03FZ4)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804320.1
- STRING:   Q03FZ4
- GeneID:   4418004
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_0818
- NMPDR:   fig|278197.10.peg.723
- eggNOG:   COG1570
- HOGENOM:   HBG634411
- OMA:   INIYLFP
- PhylomeDB:   Q03FZ4
- ProtClustDB:   PRK00286
- BioCyc:   PPEN278197:PEPE_0818-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti

EC number: =3.1.11.6

Molecular weight: Translated: 50115; Mature: 50115

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEDKYLTVSALTNYIKRKFDADPYLHRVYLVGEISNFRLRTNSHQYFSLKDENAKISAI
CCCCCEEEHHHHHHHHHHHCCCCHHHEEEEEEEECCCEEEEECCCEEEEEECCCCEEEEE
MFKSAFAKVKFQPEEGMRVIVSGRISLYPGNGSYQIYVDSMQPDGVGALYQAYEQLKIKL
EEHHHHHHEEECCCCCCEEEEEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHEEE
SQEGLFEAPKLPIPKYPRKIAIVTSPSGAVIRDIITTVSRRYPIVQLVLFPALVQGNEAA
CCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHH
NSIAAQIKMINTLDDFDTIIIGRGGGSIEDLWPFNEEVVARAIFASKLPVISSVGHETDT
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCCCCCH
TIADLVADMRAATPTAAAELATPVLTDILEELQKLQLQTIVAFRNILKMRSQQVQHLQQS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIFQEPQRLYEGYVQNVDILTEKLISLEKQQITTAEGSFKTLNSRLLANTPASRIKMAKQ
HHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHH
NVEHLRQMTNNNITNRFSKYANDLNSLIGSLDTLSPLKIMSRGYTYVTRDTKVVKSIEDL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEECCHHHHHHHHHC
SIDDKIQLNFSDGSANAVIKTINSEDK
CCCCEEEEEECCCCCCEEEEECCCCCC
>Mature Secondary Structure
MQEDKYLTVSALTNYIKRKFDADPYLHRVYLVGEISNFRLRTNSHQYFSLKDENAKISAI
CCCCCEEEHHHHHHHHHHHCCCCHHHEEEEEEEECCCEEEEECCCEEEEEECCCCEEEEE
MFKSAFAKVKFQPEEGMRVIVSGRISLYPGNGSYQIYVDSMQPDGVGALYQAYEQLKIKL
EEHHHHHHEEECCCCCCEEEEEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHEEE
SQEGLFEAPKLPIPKYPRKIAIVTSPSGAVIRDIITTVSRRYPIVQLVLFPALVQGNEAA
CCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHH
NSIAAQIKMINTLDDFDTIIIGRGGGSIEDLWPFNEEVVARAIFASKLPVISSVGHETDT
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCCCCCH
TIADLVADMRAATPTAAAELATPVLTDILEELQKLQLQTIVAFRNILKMRSQQVQHLQQS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIFQEPQRLYEGYVQNVDILTEKLISLEKQQITTAEGSFKTLNSRLLANTPASRIKMAKQ
HHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHH
NVEHLRQMTNNNITNRFSKYANDLNSLIGSLDTLSPLKIMSRGYTYVTRDTKVVKSIEDL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEECCHHHHHHHHHC
SIDDKIQLNFSDGSANAVIKTINSEDK
CCCCEEEEEECCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA