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The map label for this gene is infC [H]

Identifier: 116492467

GI number: 116492467

Start: 741626

End: 742126

Strand: Direct

Name: infC [H]

Synonym: PEPE_0699

Alternate gene names: 116492467

Gene position: 741626-742126 (Clockwise)

Preceding gene: 116492466

Following gene: 116492468

Centisome position: 40.47

GC content: 39.12

Gene sequence:

>501_bases
ATGGTAAATGAAACCATTCGGGCTAGAGAAGTCCGCTTAATTGGTGTCAACGGTGATCAATTGGGAGTTAAAACTAAGGC
TGAAGCAATTAGTATGGCTGAGGAAGCTAACTTAGACGTCGTAGTCGTATCCCCAAAGGCTAAGCCACCCGTTGCCAAGA
TTATGGATTATGGAAAATATCGATTCGAGCAACAAAAGAAACAACGTGAAGCTCGTAAAAAGCAAAAGACTGTCAGCATT
AAAGAAATTCGTTTGAGTCCTACAATTGATACAAATGATTTTAATACTAAGCTTAAAAACGCTACTAAGTTCTTGAGTAA
AGGTGATAAAGTTCGTGTTTCAATTCGTTTTAAGGGACGTGCCATCACTCATAAAGAGATTGGTCGTAAGGTACTTGAAC
GAATGGCTAAAGAAACTTCAGATGTCGCACGTGTTGAGGTTCATCCAAAGATGGACGGCAGAAGTATGTTTCTTGTGCTA
TCACCAATTGCTGATAAATAA

Upstream 100 bases:

>100_bases
TACTAATTAATTATCCAAACAAAGCGGGTGGCGTATGCCATCCGCTTTTCTGCATTCTCGCTAATTTTCCTGGAGGTGAA
GAACCATAGCAAACGATATA

Downstream 100 bases:

>100_bases
TTTAAAATTCTGGAGGAACAGATTATGCCTAAAATGAAGACAAACCGCGCTGCTGCTAAGCGTTTTAAGAAAACTGCTAA
TGGCGGTCTTAAGAGTGCAA

Product: translation initiation factor 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MVNETIRAREVRLIGVNGDQLGVKTKAEAISMAEEANLDVVVVSPKAKPPVAKIMDYGKYRFEQQKKQREARKKQKTVSI
KEIRLSPTIDTNDFNTKLKNATKFLSKGDKVRVSIRFKGRAITHKEIGRKVLERMAKETSDVARVEVHPKMDGRSMFLVL
SPIADK

Sequences:

>Translated_166_residues
MVNETIRAREVRLIGVNGDQLGVKTKAEAISMAEEANLDVVVVSPKAKPPVAKIMDYGKYRFEQQKKQREARKKQKTVSI
KEIRLSPTIDTNDFNTKLKNATKFLSKGDKVRVSIRFKGRAITHKEIGRKVLERMAKETSDVARVEVHPKMDGRSMFLVL
SPIADK
>Mature_166_residues
MVNETIRAREVRLIGVNGDQLGVKTKAEAISMAEEANLDVVVVSPKAKPPVAKIMDYGKYRFEQQKKQREARKKQKTVSI
KEIRLSPTIDTNDFNTKLKNATKFLSKGDKVRVSIRFKGRAITHKEIGRKVLERMAKETSDVARVEVHPKMDGRSMFLVL
SPIADK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=162, Percent_Identity=45.679012345679, Blast_Score=148, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 18792; Mature: 18792

Theoretical pI: Translated: 10.91; Mature: 10.91

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNETIRAREVRLIGVNGDQLGVKTKAEAISMAEEANLDVVVVSPKAKPPVAKIMDYGKY
CCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHH
RFEQQKKQREARKKQKTVSIKEIRLSPTIDTNDFNTKLKNATKFLSKGDKVRVSIRFKGR
HHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCC
AITHKEIGRKVLERMAKETSDVARVEVHPKMDGRSMFLVLSPIADK
CCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCC
>Mature Secondary Structure
MVNETIRAREVRLIGVNGDQLGVKTKAEAISMAEEANLDVVVVSPKAKPPVAKIMDYGKY
CCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHH
RFEQQKKQREARKKQKTVSIKEIRLSPTIDTNDFNTKLKNATKFLSKGDKVRVSIRFKGR
HHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCC
AITHKEIGRKVLERMAKETSDVARVEVHPKMDGRSMFLVLSPIADK
CCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12566566 [H]