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The map label for this gene is nrdR

Identifier: 116492459

GI number: 116492459

Start: 732380

End: 732853

Strand: Direct

Name: nrdR

Synonym: PEPE_0691

Alternate gene names: 116492459

Gene position: 732380-732853 (Clockwise)

Preceding gene: 116492458

Following gene: 116492460

Centisome position: 39.97

GC content: 35.44

Gene sequence:

>474_bases
ATGAAATGTCCACACTGTGGAAATAATGGATCAAGAGTTGTTGATAGTCGACCAACCGATGAAGGTCGGGTTATTCGACG
AAGAAGAGAATGTGAAAAATGTGGCTTTAGATTTACCACGTTTGAACGTGTTGAAGCAACACCATTACTAGTTATTAAGA
AAAATGGATCAAGAGAAGAGTTTGATCGAGATAAAATTTTAAAAGGGATTGTACGAGCAGCTGAAAAACGGCCCTTAAAC
ATGGAACAGATGACGGATATGGTCGATAAGGTTGAAAATAAGGTTCGTTCTTTAGGTGAGAGCGAAATTTCAAGTCAAAT
TATTGGCGAATATGTGATGAATATTTTAGTAGATTTAGATGAGATTGCTTATATTCGTTTTGCTAGTGTTTACCGTCAAT
TTAAAGATATGCATGTCTTTTTAGATGAGCTGCAAGATATGATGAAAAAAGACGAAGAAAAGGAAAAAGAGTAG

Upstream 100 bases:

>100_bases
ACCAGTGGAACAATTGAAGAGACACGAAGTCAAGTGGTAAAATGGCTTGTTGACAAGAATTTATTCTAAGCTTCCGAAGC
ATTCGGCGAGGTGAAACGAA

Downstream 100 bases:

>100_bases
ATGGCAACTGAGATGAGTGAATTAGCACCCCATGATTCATTTATAATTGATAGCCAACGTCAAATTACTGATTTTGAGCA
ACGTTCATTGACGACACTAT

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MKCPHCGNNGSRVVDSRPTDEGRVIRRRRECEKCGFRFTTFERVEATPLLVIKKNGSREEFDRDKILKGIVRAAEKRPLN
MEQMTDMVDKVENKVRSLGESEISSQIIGEYVMNILVDLDEIAYIRFASVYRQFKDMHVFLDELQDMMKKDEEKEKE

Sequences:

>Translated_157_residues
MKCPHCGNNGSRVVDSRPTDEGRVIRRRRECEKCGFRFTTFERVEATPLLVIKKNGSREEFDRDKILKGIVRAAEKRPLN
MEQMTDMVDKVENKVRSLGESEISSQIIGEYVMNILVDLDEIAYIRFASVYRQFKDMHVFLDELQDMMKKDEEKEKE
>Mature_157_residues
MKCPHCGNNGSRVVDSRPTDEGRVIRRRRECEKCGFRFTTFERVEATPLLVIKKNGSREEFDRDKILKGIVRAAEKRPLN
MEQMTDMVDKVENKVRSLGESEISSQIIGEYVMNILVDLDEIAYIRFASVYRQFKDMHVFLDELQDMMKKDEEKEKE

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=144, Percent_Identity=43.75, Blast_Score=127, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_PEDPA (Q03GC0)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804194.1
- STRING:   Q03GC0
- GeneID:   4418121
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_0691
- NMPDR:   fig|278197.10.peg.615
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   Q03GC0
- ProtClustDB:   PRK00464
- BioCyc:   PPEN278197:PEPE_0691-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 18440; Mature: 18440

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCPHCGNNGSRVVDSRPTDEGRVIRRRRECEKCGFRFTTFERVEATPLLVIKKNGSREE
CCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCEEEEEECCCCHHH
FDRDKILKGIVRAAEKRPLNMEQMTDMVDKVENKVRSLGESEISSQIIGEYVMNILVDLD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
EIAYIRFASVYRQFKDMHVFLDELQDMMKKDEEKEKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKCPHCGNNGSRVVDSRPTDEGRVIRRRRECEKCGFRFTTFERVEATPLLVIKKNGSREE
CCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCEEEEEECCCCHHH
FDRDKILKGIVRAAEKRPLNMEQMTDMVDKVENKVRSLGESEISSQIIGEYVMNILVDLD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
EIAYIRFASVYRQFKDMHVFLDELQDMMKKDEEKEKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA