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The map label for this gene is coaE [H]

Identifier: 116492458

GI number: 116492458

Start: 731758

End: 732348

Strand: Direct

Name: coaE [H]

Synonym: PEPE_0690

Alternate gene names: 116492458

Gene position: 731758-732348 (Clockwise)

Preceding gene: 116492457

Following gene: 116492459

Centisome position: 39.93

GC content: 33.84

Gene sequence:

>591_bases
ATGACAGTGATAGTTGGTCTAACTGGCGGGATTGCAATGGGTAAAACGACGATTAGCCAATTTTTGAAATCTAAAGCAAT
TCCGGTAGTTGATGCTGATCAAATTGCACACGAAATCTTAACAGTTGATGAAGTTAAAGTGAAATTGATGGATACTTTTG
GTGAAAGTATTCTAGATAAAAATCAAAATATTGATCGTCGAAAACTAGGACCAATTGTATTCAATGATCAAAGACAATTG
GAAAAGCTAAATATAATTGTGCAACCTTATATTCGAACCGAAATAGTAAGACAATTGGACACTTTTAGCGCAAGTAAGGT
AGTAGTTTTAGATGCTCCGGTGCTCTTTGAGCAAGGATATGAAAAAATGGTTGATTATTTAATGGTCATTAAAACTAGTG
CTCAAATTCAAGTAGAACGTTTAATGCAACGTGATAGTTTAAATGAAATTGACGCTCAAAAAAGAATTCAAGCTCAGATG
CCTATCGAAGAAAAGGTAAAAAAAGCTGATATTGTGATTGATACCAGTGGAACAATTGAAGAGACACGAAGTCAAGTGGT
AAAATGGCTTGTTGACAAGAATTTATTCTAA

Upstream 100 bases:

>100_bases
GGTTTGCCGTGTCAGCGATGCGGGACACCCATTGAACGGATTAAAGTGGCACAACGTGGGACCCATTTTTGCCCCCATTG
CCAAGTTTTGAGGTAGTGAT

Downstream 100 bases:

>100_bases
GCTTCCGAAGCATTCGGCGAGGTGAAACGAAATGAAATGTCCACACTGTGGAAATAATGGATCAAGAGTTGTTGATAGTC
GACCAACCGATGAAGGTCGG

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MTVIVGLTGGIAMGKTTISQFLKSKAIPVVDADQIAHEILTVDEVKVKLMDTFGESILDKNQNIDRRKLGPIVFNDQRQL
EKLNIIVQPYIRTEIVRQLDTFSASKVVVLDAPVLFEQGYEKMVDYLMVIKTSAQIQVERLMQRDSLNEIDAQKRIQAQM
PIEEKVKKADIVIDTSGTIEETRSQVVKWLVDKNLF

Sequences:

>Translated_196_residues
MTVIVGLTGGIAMGKTTISQFLKSKAIPVVDADQIAHEILTVDEVKVKLMDTFGESILDKNQNIDRRKLGPIVFNDQRQL
EKLNIIVQPYIRTEIVRQLDTFSASKVVVLDAPVLFEQGYEKMVDYLMVIKTSAQIQVERLMQRDSLNEIDAQKRIQAQM
PIEEKVKKADIVIDTSGTIEETRSQVVKWLVDKNLF
>Mature_195_residues
TVIVGLTGGIAMGKTTISQFLKSKAIPVVDADQIAHEILTVDEVKVKLMDTFGESILDKNQNIDRRKLGPIVFNDQRQLE
KLNIIVQPYIRTEIVRQLDTFSASKVVVLDAPVLFEQGYEKMVDYLMVIKTSAQIQVERLMQRDSLNEIDAQKRIQAQMP
IEEKVKKADIVIDTSGTIEETRSQVVKWLVDKNLF

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=192, Percent_Identity=36.9791666666667, Blast_Score=119, Evalue=1e-27,
Organism=Homo sapiens, GI191252795, Length=192, Percent_Identity=36.9791666666667, Blast_Score=119, Evalue=1e-27,
Organism=Homo sapiens, GI110227607, Length=188, Percent_Identity=32.4468085106383, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI205277394, Length=188, Percent_Identity=32.4468085106383, Blast_Score=94, Evalue=5e-20,
Organism=Homo sapiens, GI110227605, Length=190, Percent_Identity=32.6315789473684, Blast_Score=94, Evalue=8e-20,
Organism=Homo sapiens, GI110227603, Length=190, Percent_Identity=32.6315789473684, Blast_Score=94, Evalue=8e-20,
Organism=Homo sapiens, GI110227601, Length=190, Percent_Identity=32.6315789473684, Blast_Score=94, Evalue=8e-20,
Organism=Escherichia coli, GI1786292, Length=189, Percent_Identity=29.6296296296296, Blast_Score=82, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17554944, Length=189, Percent_Identity=38.0952380952381, Blast_Score=146, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI25143409, Length=190, Percent_Identity=33.1578947368421, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6320402, Length=193, Percent_Identity=31.6062176165803, Blast_Score=110, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24644728, Length=190, Percent_Identity=36.3157894736842, Blast_Score=127, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24658602, Length=188, Percent_Identity=35.1063829787234, Blast_Score=123, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22246; Mature: 22115

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVIVGLTGGIAMGKTTISQFLKSKAIPVVDADQIAHEILTVDEVKVKLMDTFGESILDK
CEEEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NQNIDRRKLGPIVFNDQRQLEKLNIIVQPYIRTEIVRQLDTFSASKVVVLDAPVLFEQGY
CCCCCHHHCCCEEECCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECHHHHHHHH
EKMVDYLMVIKTSAQIQVERLMQRDSLNEIDAQKRIQAQMPIEEKVKKADIVIDTSGTIE
HHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHCEEEECCCCHH
ETRSQVVKWLVDKNLF
HHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TVIVGLTGGIAMGKTTISQFLKSKAIPVVDADQIAHEILTVDEVKVKLMDTFGESILDK
EEEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NQNIDRRKLGPIVFNDQRQLEKLNIIVQPYIRTEIVRQLDTFSASKVVVLDAPVLFEQGY
CCCCCHHHCCCEEECCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECHHHHHHHH
EKMVDYLMVIKTSAQIQVERLMQRDSLNEIDAQKRIQAQMPIEEKVKKADIVIDTSGTIE
HHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHCEEEECCCCHH
ETRSQVVKWLVDKNLF
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA