Click here to switch to the map view.

The map label for this gene is sftA [H]

Identifier: 116492453

GI number: 116492453

Start: 724082

End: 725998

Strand: Direct

Name: sftA [H]

Synonym: PEPE_0685

Alternate gene names: 116492453

Gene position: 724082-725998 (Clockwise)

Preceding gene: 116492452

Following gene: 116492454

Centisome position: 39.52

GC content: 39.8

Gene sequence:

>1917_bases
ATGGTTAAATATGATGGGCCTGCTTTTTTTCGAAAAAAAGGCGTAGATTTTAATAATCCAAGTTTAAATATTCAAGAAGA
CCAAACTTCGAAGTTAAAAAATGAGGATTTTACCCCTGCTATTAAACGGCGTAAACAGGTTCCAGAGACCATTTCCCAAG
CAAAATTATCGCAGGCGGTAGATCCCATCCAACCAACGTTGGCTAAAGATACACCTGAACCAACTAAACAAGTGGTAGAG
AAAACTGAGCATCGACAGCCTCGTTTTAGAATGCCCCGTACAAAATATGAGGCACCGAAACGTCCAGCAAAGGTTATGCA
TGAAATTAAGCATCGACACCAGCTTGAGAAAAGTCATCATGAACTTGATGAAAATATTACACCGGTGATAGAAAAAAACG
TACCGAAAACGATGGTTGAAAAAGCTGTCCCAATTGAAAATAATAATCACTTTGAAGAGCAACCGCTGGAAGAAAATCCA
AGGCAGTCATTTGAACGAAGTGAAACTAATGAATTCGGGTATCAATTTCCAAGTTTGAATTTATTACCTAATCCAGTAAT
TGACACTGATAATACGGACGAGTGGGTTAATGATCAAATTCAAAGATTGAATGATGCCTTATTAGCGTTTGATGTTGATG
CTGAGGTTGTAAATTGGACTGTGGGTCCAACGGTAACTCAATTTGAAATTGAACTCGGTCGAGGAGTTAAAGTCAATAAA
ATCACGAATTTAACGGATGATTTAAAGCTGCAGTTAGCAGCTAAGGATATTCGAATTGAGGCTCCAATTCCTGGTAAAAA
TACCGTGGGGATTGAAGTACCTAACTTGCATCCTCGACCAGTGCCTTTAAGTGAAATTATTAGTTCAGATAAGTTTAAAG
CAAGTGAGTCACCATTAACCGTGGCTTTGGGAGTTGATTTGTTTGGTCAACCTCAAACTTATGATCTTCGCAAGATGCCG
CATGGTCTGATTGCTGGTGCCACTGGTTCTGGTAAAAGTGTTTTTATTAACAGTGTTTTGGTGTCGTTGTTATACAAAGC
GACTCCTCAAGAGTTGAAACTACTATTAATTGATCCCAAGACGGTTGAGTTAGCGCCATACAATGGACTGCCACATTTGC
TTGCTCCAGTTATTTCAGATCCTAAGGCCGCATCGGCTTCTTTAAAATGGGTTACCAAAGAGATGGATGAGCGTTATGAA
AGACTGGCGGCTGCAGGTGCTCGCAACATTGAGCAATATAATAAAAAGGCCGAAAAAGCCCAAGATTACGCCAATAAAAT
GCCGTACATTGTAGTTATTATCGATGAATTAGCTGATTTAATGATGGTTTCTTCTTCAGAAGTACAGGATTACATTGTAC
GAATTACGCAAAAAGCACGGGCAGCTGGGATTCATCTATTGATTGCAACCCAGCGACCTAGCGTGGACGTAGTAACCGGA
TTGATTAAAAATAATATTCCAACAAGGGTAGCGTTTATGGTATCCAGTCAAGTCGATTCAAGAACAATCTTGGATCATTC
AGGGGCAGAGCGACTCTTAGGAAGAGGAGATATGCTGTTCCTTGGAAATGGAAAGAGTAATCCGGTTCGTCTACAAGGGG
CCTTTATTGATGAAGAAATCGATGACATTACTGATTTTGTCCGAGCACAGGCTGCGCCACAATATACTTTCAATCCTAAT
GAGTTGAAAGTCCAAAGTGAAGAGTTGGATAGCGAAGACGAATTAATGGATAATGTACTTGAATTCTTAGCGGATGAGGA
AACTATCTCAACATCTAAATTACAGAGAATGTTTTCAATTGGATACAACCGAGCAGCAACCATTATGGATCAACTTGAGG
CTTCAGGATATATTTCGGAAGCTCGTGGTTCAAAACCACGGGAAGTTTTTTATGATGGAAACAATAACGAAGTGTAG

Upstream 100 bases:

>100_bases
CAGAAGAAGGGAGCATTAATTTTACCTGATGATTTCGTTGTAGGTGAAGCATTTGATTTTGAAAAAGGTAATCATATCTT
TGATTAAAGAAGGGATTTAG

Downstream 100 bases:

>100_bases
TGTGGTAAACTAAAAACAATTTAATTATAGGAGTGGTAAAGGTGGATAAAGATTCAACTTATTATTTTATCGGTATTAAG
GGGTCAGGGATGAGTTCCCT

Product: DNA segregation ATPase FtsK/SpoIIIE related protein

Products: NA

Alternate protein names: Septum-associated ftsK-like translocase of DNA [H]

Number of amino acids: Translated: 638; Mature: 638

Protein sequence:

>638_residues
MVKYDGPAFFRKKGVDFNNPSLNIQEDQTSKLKNEDFTPAIKRRKQVPETISQAKLSQAVDPIQPTLAKDTPEPTKQVVE
KTEHRQPRFRMPRTKYEAPKRPAKVMHEIKHRHQLEKSHHELDENITPVIEKNVPKTMVEKAVPIENNNHFEEQPLEENP
RQSFERSETNEFGYQFPSLNLLPNPVIDTDNTDEWVNDQIQRLNDALLAFDVDAEVVNWTVGPTVTQFEIELGRGVKVNK
ITNLTDDLKLQLAAKDIRIEAPIPGKNTVGIEVPNLHPRPVPLSEIISSDKFKASESPLTVALGVDLFGQPQTYDLRKMP
HGLIAGATGSGKSVFINSVLVSLLYKATPQELKLLLIDPKTVELAPYNGLPHLLAPVISDPKAASASLKWVTKEMDERYE
RLAAAGARNIEQYNKKAEKAQDYANKMPYIVVIIDELADLMMVSSSEVQDYIVRITQKARAAGIHLLIATQRPSVDVVTG
LIKNNIPTRVAFMVSSQVDSRTILDHSGAERLLGRGDMLFLGNGKSNPVRLQGAFIDEEIDDITDFVRAQAAPQYTFNPN
ELKVQSEELDSEDELMDNVLEFLADEETISTSKLQRMFSIGYNRAATIMDQLEASGYISEARGSKPREVFYDGNNNEV

Sequences:

>Translated_638_residues
MVKYDGPAFFRKKGVDFNNPSLNIQEDQTSKLKNEDFTPAIKRRKQVPETISQAKLSQAVDPIQPTLAKDTPEPTKQVVE
KTEHRQPRFRMPRTKYEAPKRPAKVMHEIKHRHQLEKSHHELDENITPVIEKNVPKTMVEKAVPIENNNHFEEQPLEENP
RQSFERSETNEFGYQFPSLNLLPNPVIDTDNTDEWVNDQIQRLNDALLAFDVDAEVVNWTVGPTVTQFEIELGRGVKVNK
ITNLTDDLKLQLAAKDIRIEAPIPGKNTVGIEVPNLHPRPVPLSEIISSDKFKASESPLTVALGVDLFGQPQTYDLRKMP
HGLIAGATGSGKSVFINSVLVSLLYKATPQELKLLLIDPKTVELAPYNGLPHLLAPVISDPKAASASLKWVTKEMDERYE
RLAAAGARNIEQYNKKAEKAQDYANKMPYIVVIIDELADLMMVSSSEVQDYIVRITQKARAAGIHLLIATQRPSVDVVTG
LIKNNIPTRVAFMVSSQVDSRTILDHSGAERLLGRGDMLFLGNGKSNPVRLQGAFIDEEIDDITDFVRAQAAPQYTFNPN
ELKVQSEELDSEDELMDNVLEFLADEETISTSKLQRMFSIGYNRAATIMDQLEASGYISEARGSKPREVFYDGNNNEV
>Mature_638_residues
MVKYDGPAFFRKKGVDFNNPSLNIQEDQTSKLKNEDFTPAIKRRKQVPETISQAKLSQAVDPIQPTLAKDTPEPTKQVVE
KTEHRQPRFRMPRTKYEAPKRPAKVMHEIKHRHQLEKSHHELDENITPVIEKNVPKTMVEKAVPIENNNHFEEQPLEENP
RQSFERSETNEFGYQFPSLNLLPNPVIDTDNTDEWVNDQIQRLNDALLAFDVDAEVVNWTVGPTVTQFEIELGRGVKVNK
ITNLTDDLKLQLAAKDIRIEAPIPGKNTVGIEVPNLHPRPVPLSEIISSDKFKASESPLTVALGVDLFGQPQTYDLRKMP
HGLIAGATGSGKSVFINSVLVSLLYKATPQELKLLLIDPKTVELAPYNGLPHLLAPVISDPKAASASLKWVTKEMDERYE
RLAAAGARNIEQYNKKAEKAQDYANKMPYIVVIIDELADLMMVSSSEVQDYIVRITQKARAAGIHLLIATQRPSVDVVTG
LIKNNIPTRVAFMVSSQVDSRTILDHSGAERLLGRGDMLFLGNGKSNPVRLQGAFIDEEIDDITDFVRAQAAPQYTFNPN
ELKVQSEELDSEDELMDNVLEFLADEETISTSKLQRMFSIGYNRAATIMDQLEASGYISEARGSKPREVFYDGNNNEV

Specific function: Required for the accurate completion of chromosome partitioning, in part by promoting efficient resolution of chromosome dimers, before the formation of the division septum. Binds to DNA in a non-specific manner. Shows ATPase activity. Not required for cy

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cytoplasm. Note=Colocalizes with ftsZ at nascent division sites [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=484, Percent_Identity=45.2479338842975, Blast_Score=413, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 71635; Mature: 71635

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKYDGPAFFRKKGVDFNNPSLNIQEDQTSKLKNEDFTPAIKRRKQVPETISQAKLSQAV
CCCCCCCHHHHHCCCCCCCCCCEECCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHC
DPIQPTLAKDTPEPTKQVVEKTEHRQPRFRMPRTKYEAPKRPAKVMHEIKHRHQLEKSHH
CCCCCHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ELDENITPVIEKNVPKTMVEKAVPIENNNHFEEQPLEENPRQSFERSETNEFGYQFPSLN
HHCCCCCCHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHCCCCCCCC
LLPNPVIDTDNTDEWVNDQIQRLNDALLAFDVDAEVVNWTVGPTVTQFEIELGRGVKVNK
CCCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCEEEEEECCCCEEEEEEECCCCEEEEH
ITNLTDDLKLQLAAKDIRIEAPIPGKNTVGIEVPNLHPRPVPLSEIISSDKFKASESPLT
HCCCCCCCEEEEEEECEEEECCCCCCCEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCEE
VALGVDLFGQPQTYDLRKMPHGLIAGATGSGKSVFINSVLVSLLYKATPQELKLLLIDPK
EEEECCCCCCCCCCHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCC
TVELAPYNGLPHLLAPVISDPKAASASLKWVTKEMDERYERLAAAGARNIEQYNKKAEKA
EEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDYANKMPYIVVIIDELADLMMVSSSEVQDYIVRITQKARAAGIHLLIATQRPSVDVVTG
HHHHHCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHH
LIKNNIPTRVAFMVSSQVDSRTILDHSGAERLLGRGDMLFLGNGKSNPVRLQGAFIDEEI
HHHCCCCCEEEEEECCCCCCCHHHCCCCHHHHHCCCCEEEEECCCCCCEEEEECCCHHHH
DDITDFVRAQAAPQYTFNPNELKVQSEELDSEDELMDNVLEFLADEETISTSKLQRMFSI
HHHHHHHHHHCCCCCCCCCCCEEEEHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GYNRAATIMDQLEASGYISEARGSKPREVFYDGNNNEV
CCCHHHHHHHHHHHCCCHHHHCCCCCCEEEECCCCCCC
>Mature Secondary Structure
MVKYDGPAFFRKKGVDFNNPSLNIQEDQTSKLKNEDFTPAIKRRKQVPETISQAKLSQAV
CCCCCCCHHHHHCCCCCCCCCCEECCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHC
DPIQPTLAKDTPEPTKQVVEKTEHRQPRFRMPRTKYEAPKRPAKVMHEIKHRHQLEKSHH
CCCCCHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ELDENITPVIEKNVPKTMVEKAVPIENNNHFEEQPLEENPRQSFERSETNEFGYQFPSLN
HHCCCCCCHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHCCCCCCCC
LLPNPVIDTDNTDEWVNDQIQRLNDALLAFDVDAEVVNWTVGPTVTQFEIELGRGVKVNK
CCCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCEEEEEECCCCEEEEEEECCCCEEEEH
ITNLTDDLKLQLAAKDIRIEAPIPGKNTVGIEVPNLHPRPVPLSEIISSDKFKASESPLT
HCCCCCCCEEEEEEECEEEECCCCCCCEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCEE
VALGVDLFGQPQTYDLRKMPHGLIAGATGSGKSVFINSVLVSLLYKATPQELKLLLIDPK
EEEECCCCCCCCCCHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCC
TVELAPYNGLPHLLAPVISDPKAASASLKWVTKEMDERYERLAAAGARNIEQYNKKAEKA
EEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDYANKMPYIVVIIDELADLMMVSSSEVQDYIVRITQKARAAGIHLLIATQRPSVDVVTG
HHHHHCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHH
LIKNNIPTRVAFMVSSQVDSRTILDHSGAERLLGRGDMLFLGNGKSNPVRLQGAFIDEEI
HHHCCCCCEEEEEECCCCCCCHHHCCCCHHHHHCCCCEEEEECCCCCCEEEEECCCHHHH
DDITDFVRAQAAPQYTFNPNELKVQSEELDSEDELMDNVLEFLADEETISTSKLQRMFSI
HHHHHHHHHHCCCCCCCCCCCEEEEHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GYNRAATIMDQLEASGYISEARGSKPREVFYDGNNNEV
CCCHHHHHHHHHHHCCCHHHHCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]