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The map label for this gene is cah [H]

Identifier: 116492426

GI number: 116492426

Start: 695602

End: 696240

Strand: Direct

Name: cah [H]

Synonym: PEPE_0657

Alternate gene names: 116492426

Gene position: 695602-696240 (Clockwise)

Preceding gene: 116492424

Following gene: 116492428

Centisome position: 37.96

GC content: 37.09

Gene sequence:

>639_bases
ATGCGAAAACTAAAGTATACTCAACAAGATCAGTGGGAATCAGAGGCTCGAGAAACCCAATCACCAATTCTAATTGAAAC
GGCAAAGTTAAAAGCTAAGAAAAATCAGATTGTGGATGGGTTGAAAAATTATACTGCAACAGAATTACATAAAAATTATA
ATAGTTTATCGTTAACTGCTAATGGGAAAATGGAAGCAGATCAACGAAGCTTCCAGCTGGAGGAGGTTCATTTCCATCAT
CCAGCAGAACATTGCTTTAAGGGTGAGGCTACACCGCGAGTACTAGAGGCCCACTTCGTCCATTATGGTTGCCTCAGACA
GCCTTTAGTGGTCAGTGTGACCTTTAAGTTGGGGGCTAAAAATGCTACTTTTGAAAAAATATTAACGGCTATGGATGATA
ATAAAGTGGAACAATTCATACTTTTAGATGATTTGATTCCAAAAAGGGGTTATTTTTATCGCTACATAGGTTCATTGACT
ACTCCTCCATTAACGGAGGGCGTAGAGTGGGTGGTATTTGAGCAAGCCCAAATGATTGATATTGATCAACTTAATCTCTA
TATGGCGACATTTAAGGAACAAAATAATCGAGAACTGCAAAAATTAAACCACCGAAAAATTGAAAAATATGAAATTTAA

Upstream 100 bases:

>100_bases
GATTCACATCGTTGAAGATTTACCCTGAGCAAAAAACTGGCGTAAAATTAGATAAAAAGTATACTGATGCTGTAATTGAT
TTTTTTGAAAGGAATAGATG

Downstream 100 bases:

>100_bases
GCTAAAAAGCTGGTGTCAACGAAAGTAACAGAGACAATGACTAAACAATCATTGAGAATACTTTCGATGACACCAGCTTT
TATATTGCATGGATAATTAA

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MRKLKYTQQDQWESEARETQSPILIETAKLKAKKNQIVDGLKNYTATELHKNYNSLSLTANGKMEADQRSFQLEEVHFHH
PAEHCFKGEATPRVLEAHFVHYGCLRQPLVVSVTFKLGAKNATFEKILTAMDDNKVEQFILLDDLIPKRGYFYRYIGSLT
TPPLTEGVEWVVFEQAQMIDIDQLNLYMATFKEQNNRELQKLNHRKIEKYEI

Sequences:

>Translated_212_residues
MRKLKYTQQDQWESEARETQSPILIETAKLKAKKNQIVDGLKNYTATELHKNYNSLSLTANGKMEADQRSFQLEEVHFHH
PAEHCFKGEATPRVLEAHFVHYGCLRQPLVVSVTFKLGAKNATFEKILTAMDDNKVEQFILLDDLIPKRGYFYRYIGSLT
TPPLTEGVEWVVFEQAQMIDIDQLNLYMATFKEQNNRELQKLNHRKIEKYEI
>Mature_212_residues
MRKLKYTQQDQWESEARETQSPILIETAKLKAKKNQIVDGLKNYTATELHKNYNSLSLTANGKMEADQRSFQLEEVHFHH
PAEHCFKGEATPRVLEAHFVHYGCLRQPLVVSVTFKLGAKNATFEKILTAMDDNKVEQFILLDDLIPKRGYFYRYIGSLT
TPPLTEGVEWVVFEQAQMIDIDQLNLYMATFKEQNNRELQKLNHRKIEKYEI

Specific function: Reversible hydration of carbon dioxide [H]

COG id: COG3338

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha-carbonic anhydrase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17568715, Length=222, Percent_Identity=29.7297297297297, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001148
- InterPro:   IPR018338
- InterPro:   IPR018340 [H]

Pfam domain/function: PF00194 Carb_anhydrase [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 24780; Mature: 24780

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS51144 ALPHA_CA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLKYTQQDQWESEARETQSPILIETAKLKAKKNQIVDGLKNYTATELHKNYNSLSLTA
CCCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
NGKMEADQRSFQLEEVHFHHPAEHCFKGEATPRVLEAHFVHYGCLRQPLVVSVTFKLGAK
CCCCCCHHHHCCHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCC
NATFEKILTAMDDNKVEQFILLDDLIPKRGYFYRYIGSLTTPPLTEGVEWVVFEQAQMID
CCHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCEEEEECCCCEEC
IDQLNLYMATFKEQNNRELQKLNHRKIEKYEI
HHHHHHHHHHHHCCCCHHHHHHHHHCCHHCCC
>Mature Secondary Structure
MRKLKYTQQDQWESEARETQSPILIETAKLKAKKNQIVDGLKNYTATELHKNYNSLSLTA
CCCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
NGKMEADQRSFQLEEVHFHHPAEHCFKGEATPRVLEAHFVHYGCLRQPLVVSVTFKLGAK
CCCCCCHHHHCCHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCC
NATFEKILTAMDDNKVEQFILLDDLIPKRGYFYRYIGSLTTPPLTEGVEWVVFEQAQMID
CCHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCEEEEECCCCEEC
IDQLNLYMATFKEQNNRELQKLNHRKIEKYEI
HHHHHHHHHHHHCCCCHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9108244; 7721686; 9761692 [H]