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The map label for this gene is gpmA2 [H]

Identifier: 116492204

GI number: 116492204

Start: 446688

End: 447356

Strand: Reverse

Name: gpmA2 [H]

Synonym: PEPE_0401

Alternate gene names: 116492204

Gene position: 447356-446688 (Counterclockwise)

Preceding gene: 116492205

Following gene: 116492198

Centisome position: 24.41

GC content: 38.27

Gene sequence:

>669_bases
ATGAAAACCGTCAATTATTATTTCGTCCGCCATGGACAAACTTTATTTAATCGTTATCGTCATCTTCAAGGTTGGTCAGA
CTCACCACTAACTGAAAAAGGCGTTGCAGATGCTAAGCATGCTGGTGATTTGCTTACTGATGTTAACTTTGCAAATATCT
ATTGCTCAGATACTACCCGAGCGATTAAGACTGCTCGTTACATCAATGCCCAAAACCAACATCCTAAAAATGAAAAAGAA
ATTGAGATGATTTCAGCTTTTCGCGAACAATTTTTTGGTTACTTCGAAGGAGCTAACTCAGTCGAAACAGAGTTTAAATT
GTATCAACAACACTCCACGGTTGAACCAACCTTAAATGCTATGACGGCTATGCATGGTATCAAGGTCGCTATTGATATCT
GGAAGGACGTTGACCCTTTTCATGATGCTGAAAGCTATGATGAAATTGTCACTCGGCTAAAGCAAGGATTGGATTATACC
TTTAAAAAAGCTCAAGATGGCGATCATCTGCTGGTGGTCTCCCATGGAACCTTGATTCGCATTTTAACATCCATGTTTAA
CGATCAAATCGATGTTTCTCACAGTCCTCGTAACGGAAGTGTTACGGAACTTCAGTTAACTGAAAATAGTGGACAAATTA
AATACTTTGGTAAAACTACTAAAATATAA

Upstream 100 bases:

>100_bases
GGCGTCTTTGCTTGGGGAATCGTAGACGTTATTACAATTGCTGTTTATGCACTGTTCTTTAATATCTTTAAAAAAGCATT
TAAGAAAGCATAGGAGTTAC

Downstream 100 bases:

>100_bases
AAAAGAGGCTTGACGTAAAAACGTCAAGCTTCTTTTTATACTCACTTTATTTTGTAAGCTTCTGCTCGTTGGCGATATTC
TTCAATCTCATCATCGGCTG

Product: fructose-2,6-bisphosphatase

Products: NA

Alternate protein names: BPG-dependent PGAM 2; PGAM 2; Phosphoglyceromutase 2; dPGM 2 [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MKTVNYYFVRHGQTLFNRYRHLQGWSDSPLTEKGVADAKHAGDLLTDVNFANIYCSDTTRAIKTARYINAQNQHPKNEKE
IEMISAFREQFFGYFEGANSVETEFKLYQQHSTVEPTLNAMTAMHGIKVAIDIWKDVDPFHDAESYDEIVTRLKQGLDYT
FKKAQDGDHLLVVSHGTLIRILTSMFNDQIDVSHSPRNGSVTELQLTENSGQIKYFGKTTKI

Sequences:

>Translated_222_residues
MKTVNYYFVRHGQTLFNRYRHLQGWSDSPLTEKGVADAKHAGDLLTDVNFANIYCSDTTRAIKTARYINAQNQHPKNEKE
IEMISAFREQFFGYFEGANSVETEFKLYQQHSTVEPTLNAMTAMHGIKVAIDIWKDVDPFHDAESYDEIVTRLKQGLDYT
FKKAQDGDHLLVVSHGTLIRILTSMFNDQIDVSHSPRNGSVTELQLTENSGQIKYFGKTTKI
>Mature_222_residues
MKTVNYYFVRHGQTLFNRYRHLQGWSDSPLTEKGVADAKHAGDLLTDVNFANIYCSDTTRAIKTARYINAQNQHPKNEKE
IEMISAFREQFFGYFEGANSVETEFKLYQQHSTVEPTLNAMTAMHGIKVAIDIWKDVDPFHDAESYDEIVTRLKQGLDYT
FKKAQDGDHLLVVSHGTLIRILTSMFNDQIDVSHSPRNGSVTELQLTENSGQIKYFGKTTKI

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 25405; Mature: 25405

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVNYYFVRHGQTLFNRYRHLQGWSDSPLTEKGVADAKHAGDLLTDVNFANIYCSDTTR
CCCEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCHHH
AIKTARYINAQNQHPKNEKEIEMISAFREQFFGYFEGANSVETEFKLYQQHSTVEPTLNA
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHH
MTAMHGIKVAIDIWKDVDPFHDAESYDEIVTRLKQGLDYTFKKAQDGDHLLVVSHGTLIR
HHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCEEEEEECCHHHH
ILTSMFNDQIDVSHSPRNGSVTELQLTENSGQIKYFGKTTKI
HHHHHHCCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCC
>Mature Secondary Structure
MKTVNYYFVRHGQTLFNRYRHLQGWSDSPLTEKGVADAKHAGDLLTDVNFANIYCSDTTR
CCCEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCHHH
AIKTARYINAQNQHPKNEKEIEMISAFREQFFGYFEGANSVETEFKLYQQHSTVEPTLNA
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHH
MTAMHGIKVAIDIWKDVDPFHDAESYDEIVTRLKQGLDYTFKKAQDGDHLLVVSHGTLIR
HHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCEEEEEECCHHHH
ILTSMFNDQIDVSHSPRNGSVTELQLTENSGQIKYFGKTTKI
HHHHHHCCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292 [H]