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The map label for this gene is yugS [H]

Identifier: 116492149

GI number: 116492149

Start: 393167

End: 394552

Strand: Reverse

Name: yugS [H]

Synonym: PEPE_0346

Alternate gene names: 116492149

Gene position: 394552-393167 (Counterclockwise)

Preceding gene: 116492151

Following gene: 116492147

Centisome position: 21.53

GC content: 37.09

Gene sequence:

>1386_bases
TTGGATAGCGGTCAGATAGTCTCTAACCTGATTGTGATGCTAATTACTTTTATATTAGCTTACTTTTTTGTTGCGGCAGA
ATTTGCTTTAGTGCAAACACGGCTCAGTGCCTTAGAAGAGGCTGAAAAAGAAACAACAAGTGCTCGTAAAAAGAAGAAAT
ATCAACTGGCGATGCGGATGGTTCGTAAACTTAACGAATATTTATCCACCACTCAGGTAGGTACTTCGATCTGTGGTATT
ATCTTAGGTTGGATTGGTGAATCAACCGTTGAATATTTTGTTGTTGAAGTTTTTGGAGCAACTCACCTAATTAACTCAGC
TTCTCTGCATATTGTGGGAGCAGTTGTTGGGGTTCTATTGTTAACTTACTTAGAAGTGGTTATTACAGAAATTGTTCCAA
AGAATATTAGTATCGATATTCCACTAAAAGTTTTAATGTGGGTCGTAACACCCCTCCATTATTTCCATACCACCTTTTAT
CCATTCGTTTGGTTGCTTAATGCTTCGGCCAATGGAATTGTCCGTTTGCTAGGGATGCAACCCGCCGATGAAAGTGACGA
AATATTCTCTCAAGCAGAAATTTTAAATCTTTCTCGAAATGCCGTTAGTGGCGGTGAATTGGATAAAAATGATTATGTTT
ACATGCAACGGGCTTTTGATTTTAATGATAAAGTCGCTAAAGATATCATGATTGACCGTACGCAACTGGTTGTCTTAGAT
ATTAATAGTAAAGTTGATGAAGCTCTACGTCAGTATCTTCAAAGCCGTTTCAGTCGTTTCCCAGTGGTAGCCAATAATGA
TAAAGATAAAATTCTTGGCTATATTTACAATTACGATATTATTCGTCAAAGCCAAGTTGATGGCGATATCAAAGTTAGCA
AATTACTTCGTAATATCATTACCGTTCCTGAAACGCTCGCTTTACAAGATGTTTTAGAACAAATGATTCAAAAACAGGTA
CCAATTTCAGTCGTTGTGGATGAATATGGTGGAACCAGTGGAATTATCACTGATAAGGATATTTACGAAGAAGTCTTCGG
CAACATCAATGATGAAATCGATGACGTTTCTGGTGACTATATTCATAAAGAAGAAAATGGACATTATAAAGTTAGCGGTA
AAATGACCGTTTATGATTTTGAACGTTACTTTGGCATTGATGTTCCAGATTTTGAAGAAGAAGACGTCGTTACTCTTGGT
GGTTACGTTATTGATCACAAACCAGATATCAAAGTTGGTGAACACGTCCGAATTCAAAATTATGATTTCGAAGTTCTCGA
TAATGAAAATGCCCATATCGATTGGTTCTTAGTTCACAAACTAAAACCTGAGGAACTCGCTGATGTCCCTCCTGTTGTCG
CGATAACCGAGACTTTGTTTGATTAA

Upstream 100 bases:

>100_bases
CACTATACAACATTAAAAAGAAAGCTACTTTTCATACTATTTTTAAAATTCTCGTTGTATAATGTAACAATAACTAGAAA
AAAGAAATGGGGAATTATTT

Downstream 100 bases:

>100_bases
ATAAAAAGGGAAGTAGTCCTTTAAAGGCTACTTCCTTTTTTATTTATTTAAAATATGACTCCAAAAAATTCCCAATCCCG
TTTTCCACATTACTATCCGT

Product: hemolysin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MDSGQIVSNLIVMLITFILAYFFVAAEFALVQTRLSALEEAEKETTSARKKKKYQLAMRMVRKLNEYLSTTQVGTSICGI
ILGWIGESTVEYFVVEVFGATHLINSASLHIVGAVVGVLLLTYLEVVITEIVPKNISIDIPLKVLMWVVTPLHYFHTTFY
PFVWLLNASANGIVRLLGMQPADESDEIFSQAEILNLSRNAVSGGELDKNDYVYMQRAFDFNDKVAKDIMIDRTQLVVLD
INSKVDEALRQYLQSRFSRFPVVANNDKDKILGYIYNYDIIRQSQVDGDIKVSKLLRNIITVPETLALQDVLEQMIQKQV
PISVVVDEYGGTSGIITDKDIYEEVFGNINDEIDDVSGDYIHKEENGHYKVSGKMTVYDFERYFGIDVPDFEEEDVVTLG
GYVIDHKPDIKVGEHVRIQNYDFEVLDNENAHIDWFLVHKLKPEELADVPPVVAITETLFD

Sequences:

>Translated_461_residues
MDSGQIVSNLIVMLITFILAYFFVAAEFALVQTRLSALEEAEKETTSARKKKKYQLAMRMVRKLNEYLSTTQVGTSICGI
ILGWIGESTVEYFVVEVFGATHLINSASLHIVGAVVGVLLLTYLEVVITEIVPKNISIDIPLKVLMWVVTPLHYFHTTFY
PFVWLLNASANGIVRLLGMQPADESDEIFSQAEILNLSRNAVSGGELDKNDYVYMQRAFDFNDKVAKDIMIDRTQLVVLD
INSKVDEALRQYLQSRFSRFPVVANNDKDKILGYIYNYDIIRQSQVDGDIKVSKLLRNIITVPETLALQDVLEQMIQKQV
PISVVVDEYGGTSGIITDKDIYEEVFGNINDEIDDVSGDYIHKEENGHYKVSGKMTVYDFERYFGIDVPDFEEEDVVTLG
GYVIDHKPDIKVGEHVRIQNYDFEVLDNENAHIDWFLVHKLKPEELADVPPVVAITETLFD
>Mature_461_residues
MDSGQIVSNLIVMLITFILAYFFVAAEFALVQTRLSALEEAEKETTSARKKKKYQLAMRMVRKLNEYLSTTQVGTSICGI
ILGWIGESTVEYFVVEVFGATHLINSASLHIVGAVVGVLLLTYLEVVITEIVPKNISIDIPLKVLMWVVTPLHYFHTTFY
PFVWLLNASANGIVRLLGMQPADESDEIFSQAEILNLSRNAVSGGELDKNDYVYMQRAFDFNDKVAKDIMIDRTQLVVLD
INSKVDEALRQYLQSRFSRFPVVANNDKDKILGYIYNYDIIRQSQVDGDIKVSKLLRNIITVPETLALQDVLEQMIQKQV
PISVVVDEYGGTSGIITDKDIYEEVFGNINDEIDDVSGDYIHKEENGHYKVSGKMTVYDFERYFGIDVPDFEEEDVVTLG
GYVIDHKPDIKVGEHVRIQNYDFEVLDNENAHIDWFLVHKLKPEELADVPPVVAITETLFD

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=407, Percent_Identity=35.3808353808354, Blast_Score=249, Evalue=4e-66,
Organism=Escherichia coli, GI1790664, Length=444, Percent_Identity=22.7477477477477, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI145693175, Length=431, Percent_Identity=22.969837587007, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1786879, Length=237, Percent_Identity=31.2236286919831, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI87082033, Length=272, Percent_Identity=24.6323529411765, Blast_Score=101, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 52291; Mature: 52291

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSGQIVSNLIVMLITFILAYFFVAAEFALVQTRLSALEEAEKETTSARKKKKYQLAMRM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRKLNEYLSTTQVGTSICGIILGWIGESTVEYFVVEVFGATHLINSASLHIVGAVVGVLL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LTYLEVVITEIVPKNISIDIPLKVLMWVVTPLHYFHTTFYPFVWLLNASANGIVRLLGMQ
HHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEECC
PADESDEIFSQAEILNLSRNAVSGGELDKNDYVYMQRAFDFNDKVAKDIMIDRTQLVVLD
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCEEEEEEE
INSKVDEALRQYLQSRFSRFPVVANNDKDKILGYIYNYDIIRQSQVDGDIKVSKLLRNII
CCCHHHHHHHHHHHHHHHCCCEEECCCCHHEEEEEECEEEEECCCCCCCHHHHHHHHHHH
TVPETLALQDVLEQMIQKQVPISVVVDEYGGTSGIITDKDIYEEVFGNINDEIDDVSGDY
CCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCHHCCCCCE
IHKEENGHYKVSGKMTVYDFERYFGIDVPDFEEEDVVTLGGYVIDHKPDIKVGEHVRIQN
EEECCCCCEEEECCEEEEEHHHHHCCCCCCCCCCCEEEECCEEEECCCCCCCCCEEEEEC
YDFEVLDNENAHIDWFLVHKLKPEELADVPPVVAITETLFD
CCEEEECCCCCEEEEEEEEECCHHHHHCCCCHHHHHHHHCC
>Mature Secondary Structure
MDSGQIVSNLIVMLITFILAYFFVAAEFALVQTRLSALEEAEKETTSARKKKKYQLAMRM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRKLNEYLSTTQVGTSICGIILGWIGESTVEYFVVEVFGATHLINSASLHIVGAVVGVLL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LTYLEVVITEIVPKNISIDIPLKVLMWVVTPLHYFHTTFYPFVWLLNASANGIVRLLGMQ
HHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEECC
PADESDEIFSQAEILNLSRNAVSGGELDKNDYVYMQRAFDFNDKVAKDIMIDRTQLVVLD
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCEEEEEEE
INSKVDEALRQYLQSRFSRFPVVANNDKDKILGYIYNYDIIRQSQVDGDIKVSKLLRNII
CCCHHHHHHHHHHHHHHHCCCEEECCCCHHEEEEEECEEEEECCCCCCCHHHHHHHHHHH
TVPETLALQDVLEQMIQKQVPISVVVDEYGGTSGIITDKDIYEEVFGNINDEIDDVSGDY
CCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCHHCCCCCE
IHKEENGHYKVSGKMTVYDFERYFGIDVPDFEEEDVVTLGGYVIDHKPDIKVGEHVRIQN
EEECCCCCEEEECCEEEEEHHHHHCCCCCCCCCCCEEEECCEEEECCCCCCCCCEEEEEC
YDFEVLDNENAHIDWFLVHKLKPEELADVPPVVAITETLFD
CCEEEECCCCCEEEEEEEEECCHHHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]