BacMap

Definition	Pediococcus pentosaceus ATCC 25745, complete genome.
Accession	NC_008525
Length	1,832,387

Click here to switch to the map view.

The map label for this gene is ppiB [C]

Identifier: 116492019

GI number: 116492019

Start: 252255

End: 252839

Strand: Direct

Name: ppiB [C]

Synonym: PEPE_0211

Alternate gene names: 116492019

Gene position: 252255-252839 (Clockwise)

Preceding gene: 116492018

Following gene: 116492022

Centisome position: 13.77

GC content: 38.8

Gene sequence:

>585_bases
ATGGCTTATCCACAATTAGACTTAGAAAATGCAACTGGTACAAAAGTAACTATTAAAACTAACCAAGGTGACATCAAAAT
TCAACTTTTTGATGAATTGGTACCTAAAACAGTTAAAAACTTTATTGAATTAGCAGAGAAGGGCTACTACAACGGCGTTA
TTTTTCATCGGGTGATCCCAGATTTTATGATTCAAGGTGGTGATCCTACGGGAACTGGTATGGGTGGCGAAAGCATCTAT
GGCAGAACGTTTGAAGATGAATTTTCAAATAAGCTCTATAACTTAAACGGGGCCCTATCTATGGCTAACGCCGGTCCAAA
TACTAATGGTAGTCAATTCTTTATCGTTACTAACAGTAATGTTCCTAAGCGAATGATTAAACAACTTAAAGCGGCAGAAT
TTCCTGAAGAAATTGTGGAAGCATATCGTCAAGGAGGAACTCCCTGGCTAGATGGTCGGCATACGGTCTTCGGACAAGTG
TTCGAAGGGATGGATGTTGTTAAAGCAATTAGTAAGGTAAAACGTAATGGCGAAGATCGCCCTAACGTAGATGTTGTGAT
GGAACAAGTAATCGTTGAAAAATAA

Upstream 100 bases:

>100_bases
AAAAAGCCCTTATTATAATCCGTTACTTTAGACGTGTTTTTATATTTCAAATAGATTAGAATGGTTTATGACCCAAAAAA
AGAAGCAGGAGAATTAATAA

Downstream 100 bases:

>100_bases
AGTAAAACCCTCTGAAAATTAATTTTTCGGAGGGTTTTACTTATTGTGCTAAATATTTCTGTAAATCTGCAAATTGATTT
TGAATAACTTCAGTTCCTTT

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Phosphatase; Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MAYPQLDLENATGTKVTIKTNQGDIKIQLFDELVPKTVKNFIELAEKGYYNGVIFHRVIPDFMIQGGDPTGTGMGGESIY
GRTFEDEFSNKLYNLNGALSMANAGPNTNGSQFFIVTNSNVPKRMIKQLKAAEFPEEIVEAYRQGGTPWLDGRHTVFGQV
FEGMDVVKAISKVKRNGEDRPNVDVVMEQVIVEK

Sequences:

>Translated_194_residues
MAYPQLDLENATGTKVTIKTNQGDIKIQLFDELVPKTVKNFIELAEKGYYNGVIFHRVIPDFMIQGGDPTGTGMGGESIY
GRTFEDEFSNKLYNLNGALSMANAGPNTNGSQFFIVTNSNVPKRMIKQLKAAEFPEEIVEAYRQGGTPWLDGRHTVFGQV
FEGMDVVKAISKVKRNGEDRPNVDVVMEQVIVEK
>Mature_193_residues
AYPQLDLENATGTKVTIKTNQGDIKIQLFDELVPKTVKNFIELAEKGYYNGVIFHRVIPDFMIQGGDPTGTGMGGESIYG
RTFEDEFSNKLYNLNGALSMANAGPNTNGSQFFIVTNSNVPKRMIKQLKAAEFPEEIVEAYRQGGTPWLDGRHTVFGQVF
EGMDVVKAISKVKRNGEDRPNVDVVMEQVIVEK

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

Organism=Homo sapiens, GI24308049, Length=195, Percent_Identity=47.1794871794872, Blast_Score=155, Evalue=2e-38,
Organism=Homo sapiens, GI7706339, Length=171, Percent_Identity=47.3684210526316, Blast_Score=155, Evalue=3e-38,
Organism=Homo sapiens, GI19557636, Length=180, Percent_Identity=43.8888888888889, Blast_Score=145, Evalue=3e-35,
Organism=Homo sapiens, GI4505991, Length=164, Percent_Identity=50.609756097561, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI64276486, Length=153, Percent_Identity=43.7908496732026, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI4758950, Length=201, Percent_Identity=43.2835820895522, Blast_Score=130, Evalue=7e-31,
Organism=Homo sapiens, GI10863927, Length=169, Percent_Identity=44.3786982248521, Blast_Score=123, Evalue=8e-29,
Organism=Homo sapiens, GI4826932, Length=178, Percent_Identity=42.6966292134831, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI5031987, Length=152, Percent_Identity=49.3421052631579, Blast_Score=118, Evalue=3e-27,
Organism=Homo sapiens, GI22547212, Length=179, Percent_Identity=42.4581005586592, Blast_Score=118, Evalue=4e-27,
Organism=Homo sapiens, GI7657473, Length=179, Percent_Identity=42.4581005586592, Blast_Score=118, Evalue=4e-27,
Organism=Homo sapiens, GI22547215, Length=179, Percent_Identity=42.4581005586592, Blast_Score=118, Evalue=4e-27,
Organism=Homo sapiens, GI310129267, Length=166, Percent_Identity=42.7710843373494, Blast_Score=114, Evalue=6e-26,
Organism=Homo sapiens, GI310120620, Length=166, Percent_Identity=42.7710843373494, Blast_Score=114, Evalue=6e-26,
Organism=Homo sapiens, GI45439316, Length=173, Percent_Identity=41.0404624277457, Blast_Score=114, Evalue=6e-26,
Organism=Homo sapiens, GI256017253, Length=151, Percent_Identity=45.6953642384106, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI221139811, Length=151, Percent_Identity=45.6953642384106, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI256017251, Length=151, Percent_Identity=45.6953642384106, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI303305009, Length=152, Percent_Identity=43.421052631579, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI178057341, Length=152, Percent_Identity=44.078947368421, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI5174637, Length=171, Percent_Identity=40.9356725146199, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI310110104, Length=166, Percent_Identity=41.566265060241, Blast_Score=111, Evalue=4e-25,
Organism=Homo sapiens, GI20911035, Length=185, Percent_Identity=35.1351351351351, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI209417936, Length=152, Percent_Identity=44.7368421052632, Blast_Score=110, Evalue=8e-25,
Organism=Homo sapiens, GI30102944, Length=152, Percent_Identity=44.7368421052632, Blast_Score=110, Evalue=8e-25,
Organism=Homo sapiens, GI219842199, Length=152, Percent_Identity=44.7368421052632, Blast_Score=110, Evalue=8e-25,
Organism=Homo sapiens, GI5454154, Length=177, Percent_Identity=37.2881355932203, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI6631100, Length=175, Percent_Identity=41.1428571428571, Blast_Score=109, Evalue=1e-24,
Organism=Homo sapiens, GI310127646, Length=169, Percent_Identity=41.4201183431953, Blast_Score=109, Evalue=1e-24,
Organism=Homo sapiens, GI310114371, Length=169, Percent_Identity=41.4201183431953, Blast_Score=109, Evalue=1e-24,
Organism=Homo sapiens, GI310119221, Length=169, Percent_Identity=41.4201183431953, Blast_Score=109, Evalue=1e-24,
Organism=Homo sapiens, GI42560244, Length=175, Percent_Identity=40.5714285714286, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI169163387, Length=169, Percent_Identity=40.2366863905325, Blast_Score=107, Evalue=9e-24,
Organism=Homo sapiens, GI169164185, Length=169, Percent_Identity=40.2366863905325, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI169163623, Length=169, Percent_Identity=40.2366863905325, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI150418007, Length=152, Percent_Identity=45.3947368421053, Blast_Score=103, Evalue=6e-23,
Organism=Homo sapiens, GI310132444, Length=169, Percent_Identity=39.0532544378698, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI310113152, Length=169, Percent_Identity=39.0532544378698, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI239751853, Length=174, Percent_Identity=37.9310344827586, Blast_Score=94, Evalue=7e-20,
Organism=Homo sapiens, GI113428306, Length=174, Percent_Identity=37.9310344827586, Blast_Score=94, Evalue=7e-20,
Organism=Homo sapiens, GI169214050, Length=174, Percent_Identity=37.9310344827586, Blast_Score=94, Evalue=7e-20,
Organism=Homo sapiens, GI310127745, Length=150, Percent_Identity=40, Blast_Score=94, Evalue=8e-20,
Organism=Homo sapiens, GI310119290, Length=150, Percent_Identity=40, Blast_Score=94, Evalue=8e-20,
Organism=Homo sapiens, GI310114540, Length=150, Percent_Identity=40, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI27735045, Length=170, Percent_Identity=35.8823529411765, Blast_Score=90, Evalue=9e-19,
Organism=Homo sapiens, GI14277126, Length=198, Percent_Identity=32.8282828282828, Blast_Score=88, Evalue=4e-18,
Organism=Homo sapiens, GI289803023, Length=196, Percent_Identity=31.1224489795918, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1786736, Length=186, Percent_Identity=37.0967741935484, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1789763, Length=159, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17539496, Length=171, Percent_Identity=45.0292397660819, Blast_Score=149, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI17506307, Length=193, Percent_Identity=47.6683937823834, Blast_Score=137, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17552780, Length=169, Percent_Identity=49.112426035503, Blast_Score=137, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17506311, Length=183, Percent_Identity=43.1693989071038, Blast_Score=135, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71980594, Length=179, Percent_Identity=40.7821229050279, Blast_Score=132, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI71980590, Length=169, Percent_Identity=42.603550295858, Blast_Score=131, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17532641, Length=179, Percent_Identity=41.8994413407821, Blast_Score=129, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17565860, Length=176, Percent_Identity=44.8863636363636, Blast_Score=128, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71997782, Length=150, Percent_Identity=42, Blast_Score=127, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17559074, Length=160, Percent_Identity=46.875, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17566266, Length=168, Percent_Identity=45.8333333333333, Blast_Score=124, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17552782, Length=159, Percent_Identity=44.0251572327044, Blast_Score=120, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17539498, Length=164, Percent_Identity=43.2926829268293, Blast_Score=120, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17551284, Length=173, Percent_Identity=41.6184971098266, Blast_Score=117, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17551282, Length=173, Percent_Identity=41.6184971098266, Blast_Score=116, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI32563659, Length=185, Percent_Identity=34.5945945945946, Blast_Score=101, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17532643, Length=177, Percent_Identity=36.7231638418079, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17552784, Length=180, Percent_Identity=35.5555555555556, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI115533296, Length=159, Percent_Identity=31.4465408805031, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323562, Length=175, Percent_Identity=48, Blast_Score=141, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6321848, Length=165, Percent_Identity=47.2727272727273, Blast_Score=129, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6320359, Length=155, Percent_Identity=48.3870967741936, Blast_Score=128, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6320510, Length=190, Percent_Identity=44.2105263157895, Blast_Score=126, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6323246, Length=183, Percent_Identity=39.8907103825137, Blast_Score=110, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17986117, Length=180, Percent_Identity=46.1111111111111, Blast_Score=157, Evalue=3e-39,
Organism=Drosophila melanogaster, GI19922376, Length=180, Percent_Identity=42.2222222222222, Blast_Score=146, Evalue=8e-36,
Organism=Drosophila melanogaster, GI20130249, Length=170, Percent_Identity=49.4117647058824, Blast_Score=133, Evalue=6e-32,
Organism=Drosophila melanogaster, GI19922912, Length=187, Percent_Identity=45.9893048128342, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI45549139, Length=152, Percent_Identity=48.6842105263158, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24652460, Length=180, Percent_Identity=36.6666666666667, Blast_Score=120, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24664125, Length=174, Percent_Identity=43.6781609195402, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21357783, Length=174, Percent_Identity=43.6781609195402, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17647301, Length=157, Percent_Identity=43.9490445859873, Blast_Score=117, Evalue=4e-27,
Organism=Drosophila melanogaster, GI21357249, Length=109, Percent_Identity=49.5412844036697, Blast_Score=116, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24650807, Length=177, Percent_Identity=40.6779661016949, Blast_Score=111, Evalue=3e-25,
Organism=Drosophila melanogaster, GI17136360, Length=176, Percent_Identity=40.3409090909091, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24586038, Length=180, Percent_Identity=35.5555555555556, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21355677, Length=185, Percent_Identity=32.972972972973, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24661775, Length=166, Percent_Identity=32.5301204819277, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21355237, Length=166, Percent_Identity=32.5301204819277, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24661771, Length=166, Percent_Identity=32.5301204819277, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: 780 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150
- InterPro:   IPR002130 [H]

Pfam domain/function: PF08282 Hydrolase_3; PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 21570; Mature: 21439

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYPQLDLENATGTKVTIKTNQGDIKIQLFDELVPKTVKNFIELAEKGYYNGVIFHRVIP
CCCCCCCCCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
DFMIQGGDPTGTGMGGESIYGRTFEDEFSNKLYNLNGALSMANAGPNTNGSQFFIVTNSN
HHHEECCCCCCCCCCCCCCCCCCHHHHHHHHEECCCCCEEECCCCCCCCCCEEEEEECCC
VPKRMIKQLKAAEFPEEIVEAYRQGGTPWLDGRHTVFGQVFEGMDVVKAISKVKRNGEDR
CHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
PNVDVVMEQVIVEK
CCHHHHHHHHHHCC
>Mature Secondary Structure 
AYPQLDLENATGTKVTIKTNQGDIKIQLFDELVPKTVKNFIELAEKGYYNGVIFHRVIP
CCCCCCCCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
DFMIQGGDPTGTGMGGESIYGRTFEDEFSNKLYNLNGALSMANAGPNTNGSQFFIVTNSN
HHHEECCCCCCCCCCCCCCCCCCHHHHHHHHEECCCCCEEECCCCCCCCCCEEEEEECCC
VPKRMIKQLKAAEFPEEIVEAYRQGGTPWLDGRHTVFGQVFEGMDVVKAISKVKRNGEDR
CHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
PNVDVVMEQVIVEK
CCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA