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The map label for this gene is nanE

Identifier: 116491966

GI number: 116491966

Start: 179297

End: 179986

Strand: Reverse

Name: nanE

Synonym: PEPE_0152

Alternate gene names: 116491966

Gene position: 179986-179297 (Counterclockwise)

Preceding gene: 116491967

Following gene: 116491965

Centisome position: 9.82

GC content: 43.48

Gene sequence:

>690_bases
ATGAAAAATAATTTTTTTGAGGCGGTTAAAGGTAAGTTAATTATTTCATGTCAGGCTTTGCCTAATGAGCCATTGCATAG
TTCTTTTATTATGGCTCGTATGGCAAGGGCAGCTAAAATGGCCGGGGCGGCTGGTATTCGCGCGAACTCTGTTGTGGATA
TTCAAGCAATTCAAGATGAAGCTGGATTACCGATGATCGGAATCGCAAAAACAGATTATCCTGATTCCGATGTTTTTATT
ACCCCCACTTTAAAGGAAATGCGGGCTGTGGCAGCTACTGGTGTCGAAGTTGTCGCTTGCCAAGTAACTGGTCAACGCCG
ACCCCATGATGAAAAACTTGCGGAAATCGTTCAACAATTCCGGACAGAATTTCCTAATACATTATTGATGGCTGACACTG
ATACCATTGAAAATGCACTTGAGGCAGACCGCTTGGGATTTGATATGATTGGGACCACGATGCGTGGTTACACGCCGGCC
ACCCAAGGTATGAATATTGCTGATCATGATTTTGAATATTTGAAGGAATTGCGTTCCCAAGTTACGCGACCAATTATCGC
TGAAGGAAAAATTGATACTCCCGAAAAACTAAAATGCTGTTTAGAATTAGGCTGCCACGCGGTCGTTGTTGGTGGCGCGA
TTACTCGTCCCTTGGAAATTGCCACTCGTTTTATTGAGGCCATTAAATAG

Upstream 100 bases:

>100_bases
AACTATTACAAAACTAACTTTGATTAAATCACTATTTCAAATCACATATTTAATATTGCTATATTTCACCTAAATTTGAT
AAAAGAGAAGTGTCAGTATT

Downstream 100 bases:

>100_bases
GACCCCTGTATTAAAGACTGGAATACTTGAAAAAAGTTCCAGTCTTTTTTATTTTCAGCGTATAATTAATACTAATCAAA
CCTAATCTAGGAGGATTTTT

Product: N-acetylmannosamine-6-phosphate 2-epimerase

Products: NA

Alternate protein names: ManNAc-6-P epimerase

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MKNNFFEAVKGKLIISCQALPNEPLHSSFIMARMARAAKMAGAAGIRANSVVDIQAIQDEAGLPMIGIAKTDYPDSDVFI
TPTLKEMRAVAATGVEVVACQVTGQRRPHDEKLAEIVQQFRTEFPNTLLMADTDTIENALEADRLGFDMIGTTMRGYTPA
TQGMNIADHDFEYLKELRSQVTRPIIAEGKIDTPEKLKCCLELGCHAVVVGGAITRPLEIATRFIEAIK

Sequences:

>Translated_229_residues
MKNNFFEAVKGKLIISCQALPNEPLHSSFIMARMARAAKMAGAAGIRANSVVDIQAIQDEAGLPMIGIAKTDYPDSDVFI
TPTLKEMRAVAATGVEVVACQVTGQRRPHDEKLAEIVQQFRTEFPNTLLMADTDTIENALEADRLGFDMIGTTMRGYTPA
TQGMNIADHDFEYLKELRSQVTRPIIAEGKIDTPEKLKCCLELGCHAVVVGGAITRPLEIATRFIEAIK
>Mature_229_residues
MKNNFFEAVKGKLIISCQALPNEPLHSSFIMARMARAAKMAGAAGIRANSVVDIQAIQDEAGLPMIGIAKTDYPDSDVFI
TPTLKEMRAVAATGVEVVACQVTGQRRPHDEKLAEIVQQFRTEFPNTLLMADTDTIENALEADRLGFDMIGTTMRGYTPA
TQGMNIADHDFEYLKELRSQVTRPIIAEGKIDTPEKLKCCLELGCHAVVVGGAITRPLEIATRFIEAIK

Specific function: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential)

COG id: COG3010

COG function: function code G; Putative N-acetylmannosamine-6-phosphate epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nanE family

Homologues:

Organism=Escherichia coli, GI1789617, Length=223, Percent_Identity=36.7713004484305, Blast_Score=108, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NANE_PEDPA (Q03HR3)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_803701.1
- ProteinModelPortal:   Q03HR3
- SMR:   Q03HR3
- STRING:   Q03HR3
- GeneID:   4418666
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_0152
- NMPDR:   fig|278197.10.peg.136
- eggNOG:   COG3010
- HOGENOM:   HBG296941
- OMA:   TRPQEIT
- PhylomeDB:   Q03HR3
- ProtClustDB:   PRK01130
- BioCyc:   PPEN278197:PEPE_0152-MONOMER
- HAMAP:   MF_01235
- InterPro:   IPR013785
- InterPro:   IPR007260
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70

Pfam domain/function: PF04131 NanE; SSF51366 RibP_bind_barrel

EC number: =5.1.3.9

Molecular weight: Translated: 25037; Mature: 25037

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNNFFEAVKGKLIISCQALPNEPLHSSFIMARMARAAKMAGAAGIRANSVVDIQAIQDE
CCCCHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCC
AGLPMIGIAKTDYPDSDVFITPTLKEMRAVAATGVEVVACQVTGQRRPHDEKLAEIVQQF
CCCCEEEEECCCCCCCCEEECCCHHHHHHHHHCCEEEEEEEECCCCCCCHHHHHHHHHHH
RTEFPNTLLMADTDTIENALEADRLGFDMIGTTMRGYTPATQGMNIADHDFEYLKELRSQ
HHHCCCEEEEECCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
VTRPIIAEGKIDTPEKLKCCLELGCHAVVVGGAITRPLEIATRFIEAIK
HCCCEECCCCCCCHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNNFFEAVKGKLIISCQALPNEPLHSSFIMARMARAAKMAGAAGIRANSVVDIQAIQDE
CCCCHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCC
AGLPMIGIAKTDYPDSDVFITPTLKEMRAVAATGVEVVACQVTGQRRPHDEKLAEIVQQF
CCCCEEEEECCCCCCCCEEECCCHHHHHHHHHCCEEEEEEEECCCCCCCHHHHHHHHHHH
RTEFPNTLLMADTDTIENALEADRLGFDMIGTTMRGYTPATQGMNIADHDFEYLKELRSQ
HHHCCCEEEEECCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
VTRPIIAEGKIDTPEKLKCCLELGCHAVVVGGAITRPLEIATRFIEAIK
HCCCEECCCCCCCHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA