Click here to switch to the map view.

The map label for this gene is dapB [H]

Identifier: 116491946

GI number: 116491946

Start: 157093

End: 157857

Strand: Reverse

Name: dapB [H]

Synonym: PEPE_0132

Alternate gene names: 116491946

Gene position: 157857-157093 (Counterclockwise)

Preceding gene: 116491947

Following gene: 116491945

Centisome position: 8.61

GC content: 42.88

Gene sequence:

>765_bases
ATGATAAATCAGGTTAAAACTGTTGTGATTGCTGGTTGTACAGGATCTATGGGTCAACAAACCGTTCAGTTAATCCAAAA
CTTACCGGGTTTCGAGTTAGTTGGTGGTTACGCACCACATGCCATCCCCCAAACATCTGATTATTTGGTCACTAATCAGC
TAGCTGAACTTCCGCAAGCTGACATTTGGATTGATTTCACCGTCCCCTCCGTTGTTTTTCAAAATATTAAGTATGCAATT
ACCCATGGCTATCATCCGGTCGTTGGAACTAGTGGTCTTTCAACGTCCGAAATGCATGAGCTCCAAACTTTGGCAGCTAC
TAAAGAGTTGGGAGGATTAATTGCTCCTAATTTTGGATTATCAGCTGTCCTTTTAATTCAATTTGCTAAGCAGGCTGCTA
AATATTTCCCAGAAGCTGAAGTGGTTGAAATGCATCATCAAGATAAACAAGATGCTCCATCTGGAACCGCTATTGCCACC
GCCAAAGCCATCAGCGCATCTCGTACTCATGCTAACGACTATGATGAAATTGAAACTATCCCTGGTGCTCGAGGAGGTAA
AGTTGATGGTGTTCCAATCCATTCAATTCGTTTACCGGGCTACGTTGCCCACGAACAAGTTCTCTTCGGTGGACCGGGTG
AGGCTTTAACCATTCGTCAAGATTCATTTGACCGCCAATCTTTCATGTCTGGAGTTCGACTGGCTTGTCAAAAAGTGACC
GATTTAAATACCTTAGTGGTTGGTCTAGAAAATATCTTAGATTAG

Upstream 100 bases:

>100_bases
CTTGCCATTAAATCAAAAAGAAAAGCTCAATTTAGCCCATCAGCTGGGGGTTAATCATCTTGCCGACGTGCAGTTGCATT
ACTAGGAAAGGAGCCATTAT

Downstream 100 bases:

>100_bases
GGGGCTTTATAAATGCCTGAACTCGATTCAGCTTTACAAAACCAAACTCGGCCGGCACTCTCAGCAATTAGTCGCTCTGC
CATCCGGCAATTTGATCAAC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MINQVKTVVIAGCTGSMGQQTVQLIQNLPGFELVGGYAPHAIPQTSDYLVTNQLAELPQADIWIDFTVPSVVFQNIKYAI
THGYHPVVGTSGLSTSEMHELQTLAATKELGGLIAPNFGLSAVLLIQFAKQAAKYFPEAEVVEMHHQDKQDAPSGTAIAT
AKAISASRTHANDYDEIETIPGARGGKVDGVPIHSIRLPGYVAHEQVLFGGPGEALTIRQDSFDRQSFMSGVRLACQKVT
DLNTLVVGLENILD

Sequences:

>Translated_254_residues
MINQVKTVVIAGCTGSMGQQTVQLIQNLPGFELVGGYAPHAIPQTSDYLVTNQLAELPQADIWIDFTVPSVVFQNIKYAI
THGYHPVVGTSGLSTSEMHELQTLAATKELGGLIAPNFGLSAVLLIQFAKQAAKYFPEAEVVEMHHQDKQDAPSGTAIAT
AKAISASRTHANDYDEIETIPGARGGKVDGVPIHSIRLPGYVAHEQVLFGGPGEALTIRQDSFDRQSFMSGVRLACQKVT
DLNTLVVGLENILD
>Mature_254_residues
MINQVKTVVIAGCTGSMGQQTVQLIQNLPGFELVGGYAPHAIPQTSDYLVTNQLAELPQADIWIDFTVPSVVFQNIKYAI
THGYHPVVGTSGLSTSEMHELQTLAATKELGGLIAPNFGLSAVLLIQFAKQAAKYFPEAEVVEMHHQDKQDAPSGTAIAT
AKAISASRTHANDYDEIETIPGARGGKVDGVPIHSIRLPGYVAHEQVLFGGPGEALTIRQDSFDRQSFMSGVRLACQKVT
DLNTLVVGLENILD

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=273, Percent_Identity=26.3736263736264, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 27235; Mature: 27235

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINQVKTVVIAGCTGSMGQQTVQLIQNLPGFELVGGYAPHAIPQTSDYLVTNQLAELPQA
CCCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHHHHHHHHCCCC
DIWIDFTVPSVVFQNIKYAITHGYHPVVGTSGLSTSEMHELQTLAATKELGGLIAPNFGL
CEEEEECHHHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEECCCCCH
SAVLLIQFAKQAAKYFPEAEVVEMHHQDKQDAPSGTAIATAKAISASRTHANDYDEIETI
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHCC
PGARGGKVDGVPIHSIRLPGYVAHEQVLFGGPGEALTIRQDSFDRQSFMSGVRLACQKVT
CCCCCCCCCCEEEEEEECCCEECCCEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
DLNTLVVGLENILD
HHHHHHHHHHHHCC
>Mature Secondary Structure
MINQVKTVVIAGCTGSMGQQTVQLIQNLPGFELVGGYAPHAIPQTSDYLVTNQLAELPQA
CCCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHHHHHHHHCCCC
DIWIDFTVPSVVFQNIKYAITHGYHPVVGTSGLSTSEMHELQTLAATKELGGLIAPNFGL
CEEEEECHHHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEECCCCCH
SAVLLIQFAKQAAKYFPEAEVVEMHHQDKQDAPSGTAIATAKAISASRTHANDYDEIETI
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHCC
PGARGGKVDGVPIHSIRLPGYVAHEQVLFGGPGEALTIRQDSFDRQSFMSGVRLACQKVT
CCCCCCCCCCEEEEEEECCCEECCCEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
DLNTLVVGLENILD
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA