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The map label for this gene is patA [H]

Identifier: 116491945

GI number: 116491945

Start: 155899

End: 157080

Strand: Reverse

Name: patA [H]

Synonym: PEPE_0131

Alternate gene names: 116491945

Gene position: 157080-155899 (Counterclockwise)

Preceding gene: 116491946

Following gene: 116491944

Centisome position: 8.57

GC content: 43.23

Gene sequence:

>1182_bases
ATGCCTGAACTCGATTCAGCTTTACAAAACCAAACTCGGCCGGCACTCTCAGCAATTAGTCGCTCTGCCATCCGGCAATT
TGATCAACAAGTGTCTGATATCCCGGGAATTTTAAAGTTAACGTTGGGTGAGCCCGACTTAAACACGCCAGAACACGTTA
AACAAGTTTTAATTAACGCAATCACTAATAATGCCTCCCACTACGCTCCGTCGGCCGGCTTACTGCGTTTGCGCCAAGCT
GTTAGTAAATATCTACTGAACTCAACTAATATTCGGTACAACCCAGCGAGTGAAATCTTGATCACAATCGGAGCTACCGA
AGCAATTTTTGCTACCATGCAAACCATTTTAAGTGTTGGCGACGAAGTGATTATTCCAACTCCAACCTTTCCTTTATACA
TGGCAATTGCAAAAGCAATTGATGCCACGGTGATTGAAATCGATACCTCAGATACTGATTTTGTACTCACAGCCGATGCT
TTGAAACAAGCTTTACAAGCGCACCCGAACGCCAAAATGCTAGTCCTAAATTACCCAACTAATCCGACCGGCGCAACTTA
CTCTAAAAGCAAGCTAACAGAACTCGCCCAGGTGATTCAAAATTCGAAGCTATTCGTCCTAGCAGACGAAATTTACGGTG
AACTCAGTTACGATAATAAGCACTATTCCATAGCCGAACTACTACCTTCTCGAACTATTCTTATTAATGGAATTTCTAAA
TCGTACGCTATGACTGGCTATCGGATTGGTTTCTTAGCTGCTCCGGCGACGCTCACCAGTAATATTTTAAAATTACATGG
ATTCATGGTTACCACCGCTCCCACTAGTATTATGGAGGGGGCGATCGAGGCTCTATTACATGGTCAAGACGATGTAGCCA
AGATGTGCGAACAGTATCGGTTACGCCGTGACTACCTTGTAAAGGAACTTAATCAATTAAATTTTCAAGTTCGCTCGCCC
GCTGGGACTTTTTATCTTTTTGCTAAAATTCCCATCAATTTGATCCAAAATTCGAACCAGTTGGCCTTGCAAATCGCCCA
TCAAGCTAAATTAGCCGTGATTCCTGGCAAAGTTTTCGGAGCTGGTGGTGAAGGTTATTTACGTTTCTCGTATGCAGCAT
CCATGTCCAACTTACACGAAGCCGTTCGACGGCTTACAAAATTTGTTCAGGAGGAAAAATAA

Upstream 100 bases:

>100_bases
ATCTTTCATGTCTGGAGTTCGACTGGCTTGTCAAAAAGTGACCGATTTAAATACCTTAGTGGTTGGTCTAGAAAATATCT
TAGATTAGGGGGCTTTATAA

Downstream 100 bases:

>100_bases
TATGTCAGCAATCACCGTTGCCATCCTAGGAGCCACTGGCGCCGTTGGAACCAGAATGATTGAGCAACTTGAACAGTCTA
ATATTGAAGTTCGTGATTTA

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MPELDSALQNQTRPALSAISRSAIRQFDQQVSDIPGILKLTLGEPDLNTPEHVKQVLINAITNNASHYAPSAGLLRLRQA
VSKYLLNSTNIRYNPASEILITIGATEAIFATMQTILSVGDEVIIPTPTFPLYMAIAKAIDATVIEIDTSDTDFVLTADA
LKQALQAHPNAKMLVLNYPTNPTGATYSKSKLTELAQVIQNSKLFVLADEIYGELSYDNKHYSIAELLPSRTILINGISK
SYAMTGYRIGFLAAPATLTSNILKLHGFMVTTAPTSIMEGAIEALLHGQDDVAKMCEQYRLRRDYLVKELNQLNFQVRSP
AGTFYLFAKIPINLIQNSNQLALQIAHQAKLAVIPGKVFGAGGEGYLRFSYAASMSNLHEAVRRLTKFVQEEK

Sequences:

>Translated_393_residues
MPELDSALQNQTRPALSAISRSAIRQFDQQVSDIPGILKLTLGEPDLNTPEHVKQVLINAITNNASHYAPSAGLLRLRQA
VSKYLLNSTNIRYNPASEILITIGATEAIFATMQTILSVGDEVIIPTPTFPLYMAIAKAIDATVIEIDTSDTDFVLTADA
LKQALQAHPNAKMLVLNYPTNPTGATYSKSKLTELAQVIQNSKLFVLADEIYGELSYDNKHYSIAELLPSRTILINGISK
SYAMTGYRIGFLAAPATLTSNILKLHGFMVTTAPTSIMEGAIEALLHGQDDVAKMCEQYRLRRDYLVKELNQLNFQVRSP
AGTFYLFAKIPINLIQNSNQLALQIAHQAKLAVIPGKVFGAGGEGYLRFSYAASMSNLHEAVRRLTKFVQEEK
>Mature_392_residues
PELDSALQNQTRPALSAISRSAIRQFDQQVSDIPGILKLTLGEPDLNTPEHVKQVLINAITNNASHYAPSAGLLRLRQAV
SKYLLNSTNIRYNPASEILITIGATEAIFATMQTILSVGDEVIIPTPTFPLYMAIAKAIDATVIEIDTSDTDFVLTADAL
KQALQAHPNAKMLVLNYPTNPTGATYSKSKLTELAQVIQNSKLFVLADEIYGELSYDNKHYSIAELLPSRTILINGISKS
YAMTGYRIGFLAAPATLTSNILKLHGFMVTTAPTSIMEGAIEALLHGQDDVAKMCEQYRLRRDYLVKELNQLNFQVRSPA
GTFYLFAKIPINLIQNSNQLALQIAHQAKLAVIPGKVFGAGGEGYLRFSYAASMSNLHEAVRRLTKFVQEEK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=394, Percent_Identity=24.6192893401015, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI56713256, Length=394, Percent_Identity=24.6192893401015, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI95147551, Length=318, Percent_Identity=23.5849056603774, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI169881279, Length=318, Percent_Identity=23.5849056603774, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI4507369, Length=276, Percent_Identity=24.6376811594203, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI187936925, Length=357, Percent_Identity=25.4901960784314, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI14211921, Length=357, Percent_Identity=25.4901960784314, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI19263340, Length=385, Percent_Identity=22.0779220779221, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI215599424, Length=385, Percent_Identity=22.0779220779221, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI149944424, Length=382, Percent_Identity=24.3455497382199, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI169881281, Length=182, Percent_Identity=25.2747252747253, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1788722, Length=354, Percent_Identity=30.225988700565, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1786816, Length=356, Percent_Identity=24.7191011235955, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788627, Length=374, Percent_Identity=25.9358288770053, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1790797, Length=408, Percent_Identity=22.3039215686275, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787710, Length=337, Percent_Identity=27.0029673590504, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17567663, Length=376, Percent_Identity=23.6702127659574, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17567369, Length=360, Percent_Identity=27.5, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71994476, Length=366, Percent_Identity=27.0491803278689, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI71994472, Length=366, Percent_Identity=27.0491803278689, Blast_Score=111, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6322401, Length=348, Percent_Identity=25, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322075, Length=343, Percent_Identity=24.7813411078717, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573069, Length=388, Percent_Identity=28.3505154639175, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24646114, Length=388, Percent_Identity=28.3505154639175, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI28573067, Length=388, Percent_Identity=28.3505154639175, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI28573065, Length=388, Percent_Identity=28.3505154639175, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI18859735, Length=387, Percent_Identity=22.9974160206718, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI45551451, Length=366, Percent_Identity=24.3169398907104, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24641770, Length=366, Percent_Identity=24.3169398907104, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641760, Length=366, Percent_Identity=24.3169398907104, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641768, Length=366, Percent_Identity=24.3169398907104, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641766, Length=366, Percent_Identity=24.3169398907104, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641764, Length=366, Percent_Identity=24.3169398907104, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 43143; Mature: 43012

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPELDSALQNQTRPALSAISRSAIRQFDQQVSDIPGILKLTLGEPDLNTPEHVKQVLINA
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHH
ITNNASHYAPSAGLLRLRQAVSKYLLNSTNIRYNPASEILITIGATEAIFATMQTILSVG
HHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEECCHHHHHHHHHHHHHCC
DEVIIPTPTFPLYMAIAKAIDATVIEIDTSDTDFVLTADALKQALQAHPNAKMLVLNYPT
CCEEECCCCHHHHHHHHHHHCCEEEEEECCCCCEEEEHHHHHHHHHHCCCCEEEEEECCC
NPTGATYSKSKLTELAQVIQNSKLFVLADEIYGELSYDNKHYSIAELLPSRTILINGISK
CCCCCCCCHHHHHHHHHHHCCCCEEEEEHHHHCCCCCCCCCEEHHHHCCCCEEEEECCCH
SYAMTGYRIGFLAAPATLTSNILKLHGFMVTTAPTSIMEGAIEALLHGQDDVAKMCEQYR
HHHHCCEEEEEEECCHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHH
LRRDYLVKELNQLNFQVRSPAGTFYLFAKIPINLIQNSNQLALQIAHQAKLAVIPGKVFG
HHHHHHHHHHHHCCEEEECCCCCEEEEEECCHHHHCCCCCEEEEEECCCEEEEECCCEEC
AGGEGYLRFSYAASMSNLHEAVRRLTKFVQEEK
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PELDSALQNQTRPALSAISRSAIRQFDQQVSDIPGILKLTLGEPDLNTPEHVKQVLINA
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHH
ITNNASHYAPSAGLLRLRQAVSKYLLNSTNIRYNPASEILITIGATEAIFATMQTILSVG
HHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEECCHHHHHHHHHHHHHCC
DEVIIPTPTFPLYMAIAKAIDATVIEIDTSDTDFVLTADALKQALQAHPNAKMLVLNYPT
CCEEECCCCHHHHHHHHHHHCCEEEEEECCCCCEEEEHHHHHHHHHHCCCCEEEEEECCC
NPTGATYSKSKLTELAQVIQNSKLFVLADEIYGELSYDNKHYSIAELLPSRTILINGISK
CCCCCCCCHHHHHHHHHHHCCCCEEEEEHHHHCCCCCCCCCEEHHHHCCCCEEEEECCCH
SYAMTGYRIGFLAAPATLTSNILKLHGFMVTTAPTSIMEGAIEALLHGQDDVAKMCEQYR
HHHHCCEEEEEEECCHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHH
LRRDYLVKELNQLNFQVRSPAGTFYLFAKIPINLIQNSNQLALQIAHQAKLAVIPGKVFG
HHHHHHHHHHHHCCEEEECCCCCEEEEEECCHHHHCCCCCEEEEEECCCEEEEECCCEEC
AGGEGYLRFSYAASMSNLHEAVRRLTKFVQEEK
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2104615 [H]