Click here to switch to the map view.

The map label for this gene is asd [H]

Identifier: 116491944

GI number: 116491944

Start: 154851

End: 155897

Strand: Reverse

Name: asd [H]

Synonym: PEPE_0130

Alternate gene names: 116491944

Gene position: 155897-154851 (Counterclockwise)

Preceding gene: 116491945

Following gene: 116491943

Centisome position: 8.51

GC content: 44.6

Gene sequence:

>1047_bases
ATGTCAGCAATCACCGTTGCCATCCTAGGAGCCACTGGCGCCGTTGGAACCAGAATGATTGAGCAACTTGAACAGTCTAA
TATTGAAGTTCGTGATTTAAGACTACTCGCGTCGCCCCGTTCCGTCGGCAAAGTTCAAACTTTTCGCGGTCAAGAATATG
AAGTATCCGCCGCAACTCCTGATTCATTTATCGGGGTGGACTTAGTTTTATCCTCAGCTGGTGGCTCAGTTTCTAAAAAA
TTAATTCCCCACGCTGTAAAAAACGGCGCGGTCTGTATCGACAACACTAGTGCCTTTCGTATGGATCCAGAAGTTCCCCT
GGTTATTCCCGAGGTCAATTCTGATGATCTTGATTGGCATCACGGGATAATTGCTAATCCTAACTGTAGTACCATCCAAA
TGTTGGTAGCACTCGCCCCGCTTGATCGAAAATACGGTCTAAATCGGATTATTGTTTCAACCTATCAGGCTGCTTCTGGA
GCTGGTCAATCGGCTTGGAGTGAACTATTAGAGGAAGCTCGCCAACATCTTGATGGGCAAGCTGAAATAGCTAAAATTTT
GCCAGTTAGTGGCGCATCTCATCATTATCCTTTAGCATTTAATTTACTTCCTCAAATCGATGTTTTTGAAGATAACGGTT
ATACCCATGAAGAGTGGAAAATGATTCATGAATCCAAAAAAATTTTACGCCACGACTTGAATAATTCAGATTTAAAAGTG
ACGGCGACCTGTGTTCGGGTTCCTGTCCCCGTCGGGCATGGCGAATCCGTATACTTTGAATTAGAACAAAATCCATCGGT
GCCAGAAATTCAGACCGTTTTGGACCAAGCTGATGGCATCGTTTTGCAAGATGATCCCCGCACTCAGCTTTATCCTCAAC
CCATCACCGCTGAAGGACACCAATCCACTTTCGTCGGACGAATCCGAGCTGACGCTGAAAATCCAGGAGGTTATAATCTC
TGGGTTGTTTCTGATAATCTACTTAAAGGAGCGGCTTGGAATGCCGTCCAAATCGCCGAAACTTTAGTTCAAAGAGAATT
ACTGTAA

Upstream 100 bases:

>100_bases
GGTGGTGAAGGTTATTTACGTTTCTCGTATGCAGCATCCATGTCCAACTTACACGAAGCCGTTCGACGGCTTACAAAATT
TGTTCAGGAGGAAAAATAAT

Downstream 100 bases:

>100_bases
ATACCCTTACGTAACAAAAAAGTAGCATCCGACTTAATTTATAAGACGTTGCTACTTTTTGTCGTGCCACTGATTAAACC
AACTTTGCTTAAAAGTGAAA

Product: aspartate semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MSAITVAILGATGAVGTRMIEQLEQSNIEVRDLRLLASPRSVGKVQTFRGQEYEVSAATPDSFIGVDLVLSSAGGSVSKK
LIPHAVKNGAVCIDNTSAFRMDPEVPLVIPEVNSDDLDWHHGIIANPNCSTIQMLVALAPLDRKYGLNRIIVSTYQAASG
AGQSAWSELLEEARQHLDGQAEIAKILPVSGASHHYPLAFNLLPQIDVFEDNGYTHEEWKMIHESKKILRHDLNNSDLKV
TATCVRVPVPVGHGESVYFELEQNPSVPEIQTVLDQADGIVLQDDPRTQLYPQPITAEGHQSTFVGRIRADAENPGGYNL
WVVSDNLLKGAAWNAVQIAETLVQRELL

Sequences:

>Translated_348_residues
MSAITVAILGATGAVGTRMIEQLEQSNIEVRDLRLLASPRSVGKVQTFRGQEYEVSAATPDSFIGVDLVLSSAGGSVSKK
LIPHAVKNGAVCIDNTSAFRMDPEVPLVIPEVNSDDLDWHHGIIANPNCSTIQMLVALAPLDRKYGLNRIIVSTYQAASG
AGQSAWSELLEEARQHLDGQAEIAKILPVSGASHHYPLAFNLLPQIDVFEDNGYTHEEWKMIHESKKILRHDLNNSDLKV
TATCVRVPVPVGHGESVYFELEQNPSVPEIQTVLDQADGIVLQDDPRTQLYPQPITAEGHQSTFVGRIRADAENPGGYNL
WVVSDNLLKGAAWNAVQIAETLVQRELL
>Mature_347_residues
SAITVAILGATGAVGTRMIEQLEQSNIEVRDLRLLASPRSVGKVQTFRGQEYEVSAATPDSFIGVDLVLSSAGGSVSKKL
IPHAVKNGAVCIDNTSAFRMDPEVPLVIPEVNSDDLDWHHGIIANPNCSTIQMLVALAPLDRKYGLNRIIVSTYQAASGA
GQSAWSELLEEARQHLDGQAEIAKILPVSGASHHYPLAFNLLPQIDVFEDNGYTHEEWKMIHESKKILRHDLNNSDLKVT
ATCVRVPVPVGHGESVYFELEQNPSVPEIQTVLDQADGIVLQDDPRTQLYPQPITAEGHQSTFVGRIRADAENPGGYNLW
VVSDNLLKGAAWNAVQIAETLVQRELL

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=345, Percent_Identity=32.7536231884058, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1789841, Length=362, Percent_Identity=27.0718232044199, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37949; Mature: 37818

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAITVAILGATGAVGTRMIEQLEQSNIEVRDLRLLASPRSVGKVQTFRGQEYEVSAATP
CCEEEEEEEECCCHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEECCCCEEEEECCCC
DSFIGVDLVLSSAGGSVSKKLIPHAVKNGAVCIDNTSAFRMDPEVPLVIPEVNSDDLDWH
CCCEEEEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCEEECCCCCEEEECCCCCCCCCC
HGIIANPNCSTIQMLVALAPLDRKYGLNRIIVSTYQAASGAGQSAWSELLEEARQHLDGQ
CCEEECCCCHHHHHHHHHCCCHHHCCCCEEEEEEEHHCCCCCHHHHHHHHHHHHHHCCCH
AEIAKILPVSGASHHYPLAFNLLPQIDVFEDNGYTHEEWKMIHESKKILRHDLNNSDLKV
HEEEEEEECCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEE
TATCVRVPVPVGHGESVYFELEQNPSVPEIQTVLDQADGIVLQDDPRTQLYPQPITAEGH
EEEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCC
QSTFVGRIRADAENPGGYNLWVVSDNLLKGAAWNAVQIAETLVQRELL
CCEEEEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SAITVAILGATGAVGTRMIEQLEQSNIEVRDLRLLASPRSVGKVQTFRGQEYEVSAATP
CEEEEEEEECCCHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEECCCCEEEEECCCC
DSFIGVDLVLSSAGGSVSKKLIPHAVKNGAVCIDNTSAFRMDPEVPLVIPEVNSDDLDWH
CCCEEEEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCEEECCCCCEEEECCCCCCCCCC
HGIIANPNCSTIQMLVALAPLDRKYGLNRIIVSTYQAASGAGQSAWSELLEEARQHLDGQ
CCEEECCCCHHHHHHHHHCCCHHHCCCCEEEEEEEHHCCCCCHHHHHHHHHHHHHHCCCH
AEIAKILPVSGASHHYPLAFNLLPQIDVFEDNGYTHEEWKMIHESKKILRHDLNNSDLKV
HEEEEEEECCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEE
TATCVRVPVPVGHGESVYFELEQNPSVPEIQTVLDQADGIVLQDDPRTQLYPQPITAEGH
EEEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCC
QSTFVGRIRADAENPGGYNLWVVSDNLLKGAAWNAVQIAETLVQRELL
CCEEEEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8098035; 9384377; 8345520 [H]