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The map label for this gene is bglA [H]

Identifier: 116491923

GI number: 116491923

Start: 114093

End: 115529

Strand: Direct

Name: bglA [H]

Synonym: PEPE_0106

Alternate gene names: 116491923

Gene position: 114093-115529 (Clockwise)

Preceding gene: 116491922

Following gene: 116491924

Centisome position: 6.23

GC content: 42.03

Gene sequence:

>1437_bases
ATGACAAAATTACCAGAAAACTTTTTATGGGGCGGCGCTGTGGCTGCTCATCAATTAGAAGGAGCATGGCAAGCAGATGG
TAAAGGGGTTAGCATGGCCGACGTGATGACGGCGGGAGCTAACAAGGTACCGCGGAAGATTACCGATGGGGTAGTGCCGG
GTGAAAATTACCCTAACCACGAAGGAATCGATTTTTACCATCATTATCGTGAAGACGTTAAAATGTTTGCCGAATTAGGC
TTAAAAGCTTTCCGTACTTCGATTGCTTGGACCCGCATCTTTCCTAATGGTGATGATGCTGAACCTAATGAAGCTGGTTT
GAAATTTTATGACGACCTCTTTGATGAATGCTTGAAATATGGGATTGAACCGGTAATTACCTTGGCACATTTTGAAATGC
CTTATCATTTAGTTAAGAAATACAATGGTTTTTCTGACCGTCACGTAATTGATCTTTATGTTCGTTTCGCTGAAACTTGT
TTCAAACGCTATAAAGATAAGGTTAAGTATTGGATGACGTTCAACGAAATCAATAATCAGAGTATGTACAATAATGACTT
CTTGATGGCTACCAACTCAGGATTAGTTTTCAAGGGGGATGAAAATCGTGAAGCAGCGATGTATCAAGCTGCTCACTATG
AATTAGTAGCTAGTGCTAAAGCAGTTAAGTTGGGTCATGAAATTAATCCAGACTTCCAAATCGGTTGCATGATTAATTTC
ACGCCATTTTATCCGCTCAATGCAGCCCCAAATAACATCATGTTGGCTGAACGTTTAATGCAACGTCGCTACTGGTTCTC
CGATGTGCATGTCAACGGGGTTTATCCAGAAAATGTTGAAACTTACTTGCAACAAAAGGGTTACCGTCCAGACATTACAG
AAGCGGACCGTGAAATCCTTAAAGCCGGAACAGTGGATTATGTAGGCTTTAGTTACTACAATTCCAACACTGTGGCTCTT
CCTGAAGGTCGGTCAATTGATGAAAACTTAGCTCCAGAAGACGTAACGGTTGAAAATCCATACCTTGCAACTAGTGATTG
GGATTGGCCAATTGATCCAGTGGGTCTCCGTTATTCCCTCAATTGGTTAAACGACCGCTACCACTTACCAATGTTTATTG
TTGAAAATGGATTAGGGGCTTACGATACGGTCGAAAGTGACGGGGCAATTCATGATCCATACCGTGTGGATTACCTCCGA
GCTCACATCCAAGAAATGGAAAAAGCAGTTGAATTAGATGGCGTAAACTTGATGGGTTATACTCCATGGGGCTTTATCGA
CCTCGTTTCAGCTGGCACTGGTCAAATGTCTAAACGCTACGGCTTTATCTATGTTGATAAGGATGATGATGGCAACGGAA
CGCTCCAACGTTCTAAGAAAGATTCCTTTGGCTGGTATCAAAAAGTAATTCGTACAAACGGTGAAGATCTCGATTAA

Upstream 100 bases:

>100_bases
GTTTGCCGTGAAAGCTATACAAAAAATGGAAAATAGTTCAAACTTATCTATGAAAAGGCTTTCTACAGAAAAAGCTCATT
AAAAGAGAGGATGGATGAAA

Downstream 100 bases:

>100_bases
AATTATTTTCCCTATCCTCTCCAAGCGTTGAGACAAGCGTTAAAATGCGTTGCTATGCTAAAATAGTAGTAGAGAACGGA
TACATTTTAGAACGAGGAGG

Product: Beta-glucosidase/6-phospho-beta- glucosidase/beta-galactosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MTKLPENFLWGGAVAAHQLEGAWQADGKGVSMADVMTAGANKVPRKITDGVVPGENYPNHEGIDFYHHYREDVKMFAELG
LKAFRTSIAWTRIFPNGDDAEPNEAGLKFYDDLFDECLKYGIEPVITLAHFEMPYHLVKKYNGFSDRHVIDLYVRFAETC
FKRYKDKVKYWMTFNEINNQSMYNNDFLMATNSGLVFKGDENREAAMYQAAHYELVASAKAVKLGHEINPDFQIGCMINF
TPFYPLNAAPNNIMLAERLMQRRYWFSDVHVNGVYPENVETYLQQKGYRPDITEADREILKAGTVDYVGFSYYNSNTVAL
PEGRSIDENLAPEDVTVENPYLATSDWDWPIDPVGLRYSLNWLNDRYHLPMFIVENGLGAYDTVESDGAIHDPYRVDYLR
AHIQEMEKAVELDGVNLMGYTPWGFIDLVSAGTGQMSKRYGFIYVDKDDDGNGTLQRSKKDSFGWYQKVIRTNGEDLD

Sequences:

>Translated_478_residues
MTKLPENFLWGGAVAAHQLEGAWQADGKGVSMADVMTAGANKVPRKITDGVVPGENYPNHEGIDFYHHYREDVKMFAELG
LKAFRTSIAWTRIFPNGDDAEPNEAGLKFYDDLFDECLKYGIEPVITLAHFEMPYHLVKKYNGFSDRHVIDLYVRFAETC
FKRYKDKVKYWMTFNEINNQSMYNNDFLMATNSGLVFKGDENREAAMYQAAHYELVASAKAVKLGHEINPDFQIGCMINF
TPFYPLNAAPNNIMLAERLMQRRYWFSDVHVNGVYPENVETYLQQKGYRPDITEADREILKAGTVDYVGFSYYNSNTVAL
PEGRSIDENLAPEDVTVENPYLATSDWDWPIDPVGLRYSLNWLNDRYHLPMFIVENGLGAYDTVESDGAIHDPYRVDYLR
AHIQEMEKAVELDGVNLMGYTPWGFIDLVSAGTGQMSKRYGFIYVDKDDDGNGTLQRSKKDSFGWYQKVIRTNGEDLD
>Mature_477_residues
TKLPENFLWGGAVAAHQLEGAWQADGKGVSMADVMTAGANKVPRKITDGVVPGENYPNHEGIDFYHHYREDVKMFAELGL
KAFRTSIAWTRIFPNGDDAEPNEAGLKFYDDLFDECLKYGIEPVITLAHFEMPYHLVKKYNGFSDRHVIDLYVRFAETCF
KRYKDKVKYWMTFNEINNQSMYNNDFLMATNSGLVFKGDENREAAMYQAAHYELVASAKAVKLGHEINPDFQIGCMINFT
PFYPLNAAPNNIMLAERLMQRRYWFSDVHVNGVYPENVETYLQQKGYRPDITEADREILKAGTVDYVGFSYYNSNTVALP
EGRSIDENLAPEDVTVENPYLATSDWDWPIDPVGLRYSLNWLNDRYHLPMFIVENGLGAYDTVESDGAIHDPYRVDYLRA
HIQEMEKAVELDGVNLMGYTPWGFIDLVSAGTGQMSKRYGFIYVDKDDDGNGTLQRSKKDSFGWYQKVIRTNGEDLD

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI13273313, Length=491, Percent_Identity=29.7352342158859, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI32481206, Length=501, Percent_Identity=30.938123752495, Blast_Score=196, Evalue=5e-50,
Organism=Homo sapiens, GI110681710, Length=495, Percent_Identity=29.8989898989899, Blast_Score=189, Evalue=7e-48,
Organism=Homo sapiens, GI24497614, Length=489, Percent_Identity=29.4478527607362, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI28376633, Length=488, Percent_Identity=26.844262295082, Blast_Score=162, Evalue=7e-40,
Organism=Escherichia coli, GI2367174, Length=474, Percent_Identity=57.8059071729958, Blast_Score=587, Evalue=1e-169,
Organism=Escherichia coli, GI1789070, Length=482, Percent_Identity=48.1327800829876, Blast_Score=473, Evalue=1e-134,
Organism=Escherichia coli, GI2367270, Length=478, Percent_Identity=49.7907949790795, Blast_Score=451, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17552856, Length=477, Percent_Identity=29.559748427673, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17539390, Length=497, Percent_Identity=27.9678068410463, Blast_Score=175, Evalue=6e-44,
Organism=Drosophila melanogaster, GI21356577, Length=501, Percent_Identity=28.5429141716567, Blast_Score=163, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 54713; Mature: 54582

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLPENFLWGGAVAAHQLEGAWQADGKGVSMADVMTAGANKVPRKITDGVVPGENYPNH
CCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHCCCCCCCCCCCC
EGIDFYHHYREDVKMFAELGLKAFRTSIAWTRIFPNGDDAEPNEAGLKFYDDLFDECLKY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
GIEPVITLAHFEMPYHLVKKYNGFSDRHVIDLYVRFAETCFKRYKDKVKYWMTFNEINNQ
CCCCEEEEEHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCC
SMYNNDFLMATNSGLVFKGDENREAAMYQAAHYELVASAKAVKLGHEINPDFQIGCMINF
CEECCCEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEC
TPFYPLNAAPNNIMLAERLMQRRYWFSDVHVNGVYPENVETYLQQKGYRPDITEADREIL
CCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHH
KAGTVDYVGFSYYNSNTVALPEGRSIDENLAPEDVTVENPYLATSDWDWPIDPVGLRYSL
HCCCEEEEEEEEECCCEEECCCCCCCCCCCCCCCEEECCCEEECCCCCCCCCCCCEEEEE
NWLNDRYHLPMFIVENGLGAYDTVESDGAIHDPYRVDYLRAHIQEMEKAVELDGVNLMGY
EECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEE
TPWGFIDLVSAGTGQMSKRYGFIYVDKDDDGNGTLQRSKKDSFGWYQKVIRTNGEDLD
CCCCHHHHHCCCCCCHHHCEEEEEEECCCCCCCCEECCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TKLPENFLWGGAVAAHQLEGAWQADGKGVSMADVMTAGANKVPRKITDGVVPGENYPNH
CCCCCCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHCCCCCCCCCCCC
EGIDFYHHYREDVKMFAELGLKAFRTSIAWTRIFPNGDDAEPNEAGLKFYDDLFDECLKY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
GIEPVITLAHFEMPYHLVKKYNGFSDRHVIDLYVRFAETCFKRYKDKVKYWMTFNEINNQ
CCCCEEEEEHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCC
SMYNNDFLMATNSGLVFKGDENREAAMYQAAHYELVASAKAVKLGHEINPDFQIGCMINF
CEECCCEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEC
TPFYPLNAAPNNIMLAERLMQRRYWFSDVHVNGVYPENVETYLQQKGYRPDITEADREIL
CCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHH
KAGTVDYVGFSYYNSNTVALPEGRSIDENLAPEDVTVENPYLATSDWDWPIDPVGLRYSL
HCCCEEEEEEEEECCCEEECCCCCCCCCCCCCCCEEECCCEEECCCCCCCCCCCCEEEEE
NWLNDRYHLPMFIVENGLGAYDTVESDGAIHDPYRVDYLRAHIQEMEKAVELDGVNLMGY
EECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEE
TPWGFIDLVSAGTGQMSKRYGFIYVDKDDDGNGTLQRSKKDSFGWYQKVIRTNGEDLD
CCCCHHHHHCCCCCCHHHCEEEEEEECCCCCCCCEECCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8125345; 9384377 [H]