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The map label for this gene is secA2

Identifier: 116491880

GI number: 116491880

Start: 63976

End: 66345

Strand: Direct

Name: secA2

Synonym: PEPE_0062

Alternate gene names: 116491880

Gene position: 63976-66345 (Clockwise)

Preceding gene: 116491879

Following gene: 116491881

Centisome position: 3.49

GC content: 38.44

Gene sequence:

>2370_bases
ATGGAATTTAATTTGGATAACTTTCGCTTAAGAAAGTATTCGAAAATCACAAAAAAAATTTTAGCACTAGGTAAAAAATA
CCAGACTTTAACGGATGATCAGTTACGTATAAAAACGGAAACGCTGAGAAATAAGCTGGTAAAAGGTGCTAGTTTAGATT
CTATACTAATTGAAGCCTACGCCACCATCCGTGAAGCAGATTTTCGAGTTTTAGGGTTGAAGCCCTTTGAAAACCAGGTT
TTGGGAGCCGTGGTGCTCCATTATGGGAATGTGGCACAAATGAATACGGGAGAAGGTAAGACTTTGACCGCTACCATGCC
CTTATATTTAAACGGTTTAACTGGCCCAGGAAATTTTTTAGTTACGGTTAATAGTTATCTAGCTAACCGAGACGCAGAAG
AGATTGGTAAAGTTTATAAATGGATGGGATTAACCTGTGCCTCAGGGGTGAGTTTAGACGATGAAGAATTGGATAAAAAG
GCTATTTATCAAAATGATATCGTTTATACCACTAATAGTGAACTGGGATTTGATTATTTAACCGATAATTTAGTCGATAA
TATTAATAAAAAGAAATTAAATGATTTGAATTTCGCTTTAGTCGACGAAGTAGATTCCGTTTTACTGGATTTAGCGCAAA
CCCCGTTGGTCATTTCAGGAGCCCCTCGGGTCCAATCCAATCTGTTCGTATCAACGGATCGGATTGTTAAAAGTTTAAAA
CCAAATGTAGATTTTGAATTTAGTGAAGACTTGAAGGATGTCTGGTTTACCCAAACCGGTATCGAACAGTTGGAAGAGTA
TCTAGGAATCCAAGGTTTAATTTCGGATAAGTGGTCGGACTTTTACCGCCATTTAGTTCTAGCACTAAAAGCTAACTACG
TTATGAAACGAAATCAAGACTATATCGTAACTAATAGGGAAGTCCTGTTGCTAGATAGCGAAAATGGGAGAGCCTTAACG
GGGATGAAGTTAGAAGCCGGAATTCATCAGGCTATTGAAGCAAAAGAGGAAGTTGAACTTAGTGACCAAACGCGATCTAT
GGCTTCGATTACGTTACAAAATTTTTTCAAGATGTTTCGGAAGTTATCGGGCATGACTGGTACGGCTAAGTCTTCTGCTC
GTGAATTTTTAGAGGTTTACAATTTGCCAGTTTTAAAAATTCCAACTCATAAACCTAACATTAGGATTGATCATGCAGAT
GTTGTCTTTGCGACCATGGATGAAAAAATTGAAGCAACCGTTCGGATGGTTAAGGCAGCGTATCAGATCAAGAGACCGGT
CTTGTTAAAGACGGGTTCGCTGTCTTTATCCAGACTCTATTCGCGAGTACTACTGGAACATGGCATTGTACACAATGTAT
TAAATGCTCAAAGTGAATCTAAAGAGGCGATGATAGTGGCTAGCGCTGGTAAATCGGGCGCGATTACGGTTGCTACATCA
ATGGCTGGGCGCGGAACCGATATTAAATTGGGTAAAGGCGTCAAAGAAAAGGGCGGTTTACTGGTAATTGGTACGGAACG
CATGGATAGTCGGCGAGTTGATGATCAACTACGGGGACGCGCCGGCCGGCAAGGTGATCCTGGGGAAAGTATTTTTCTAG
TTTCATTGGACGATAAGGTTGTTATTGAAAACGCACCAGATTGGGTAGAAAAATATCGTTTAAAGCTTGAACAAGCCGTG
GAGCAAGGTAAACGCAAATATGGCGCTCCACTAAAGGGACGCCGCGCTAGAAAAATTGTCGAAAAGGCTCAACAAGCGGC
TGATTCAGCAGCTGAAGAAAGTCGAAAAAATGCGGTAAAGATGGATGATATTTTACGAATTCAAAGAGAATTAATTTATG
ATTTTCGCGATTATATTATGAAATCAACCGATTTGACCACAATGGTTCAACAAATTAAAAATGATTATTTTAACGCGATT
GCTAGAGAGAATAAAAAAGATGCTGGAAAATTATTAGATTTTATTATCAATAATGTTGATTACAACTACATGGATAACGA
TTTCAATCCTGAGATTTTAGAAAGTACCGCTGATATAAAACAATATCTTGAAGAGATAGCACGTAATCGATGGAGCCAGC
AACAAATGATTGTTAATAACAAATTTAAACAAAACTATTTAGAACGATTGGCCGTTCTAAAAGCCTTGGATGTAGCCTGG
ATTGAGCAAGTAGATAACTTACAACAACTAAAAACGGTTGTAACGAGCCGCTCGTCTGGTCAACATAATCCGGTTTTTGA
ATATGAAAAAGAGGCCATGCATTCATTTGAACAAATGAAGAAGTTATTCTGGAAAAATACAGTTAAATATATGCTGTTGT
CAGAATTAATACCTGGTAAAAATGGATCAGTTAGGGTGGAATTTCCATGA

Upstream 100 bases:

>100_bases
GATTAAATCAATTTTTTTATAAAAAGTAAACAGAATATTGTAAAACAGTAAAATGAAAAACAATATAATATACAGAAACG
ATAAAAACAGGGGTAGGAAA

Downstream 100 bases:

>100_bases
AGAATAAATTTATCCATAGTGAATTGTTTTCGAAGGTTTTATTTACTTTGATGATGGTAGTTTTAATGGAATTAGGTCGT
CAAATTGTAATTCCATCTTT

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 789; Mature: 789

Protein sequence:

>789_residues
MEFNLDNFRLRKYSKITKKILALGKKYQTLTDDQLRIKTETLRNKLVKGASLDSILIEAYATIREADFRVLGLKPFENQV
LGAVVLHYGNVAQMNTGEGKTLTATMPLYLNGLTGPGNFLVTVNSYLANRDAEEIGKVYKWMGLTCASGVSLDDEELDKK
AIYQNDIVYTTNSELGFDYLTDNLVDNINKKKLNDLNFALVDEVDSVLLDLAQTPLVISGAPRVQSNLFVSTDRIVKSLK
PNVDFEFSEDLKDVWFTQTGIEQLEEYLGIQGLISDKWSDFYRHLVLALKANYVMKRNQDYIVTNREVLLLDSENGRALT
GMKLEAGIHQAIEAKEEVELSDQTRSMASITLQNFFKMFRKLSGMTGTAKSSAREFLEVYNLPVLKIPTHKPNIRIDHAD
VVFATMDEKIEATVRMVKAAYQIKRPVLLKTGSLSLSRLYSRVLLEHGIVHNVLNAQSESKEAMIVASAGKSGAITVATS
MAGRGTDIKLGKGVKEKGGLLVIGTERMDSRRVDDQLRGRAGRQGDPGESIFLVSLDDKVVIENAPDWVEKYRLKLEQAV
EQGKRKYGAPLKGRRARKIVEKAQQAADSAAEESRKNAVKMDDILRIQRELIYDFRDYIMKSTDLTTMVQQIKNDYFNAI
ARENKKDAGKLLDFIINNVDYNYMDNDFNPEILESTADIKQYLEEIARNRWSQQQMIVNNKFKQNYLERLAVLKALDVAW
IEQVDNLQQLKTVVTSRSSGQHNPVFEYEKEAMHSFEQMKKLFWKNTVKYMLLSELIPGKNGSVRVEFP

Sequences:

>Translated_789_residues
MEFNLDNFRLRKYSKITKKILALGKKYQTLTDDQLRIKTETLRNKLVKGASLDSILIEAYATIREADFRVLGLKPFENQV
LGAVVLHYGNVAQMNTGEGKTLTATMPLYLNGLTGPGNFLVTVNSYLANRDAEEIGKVYKWMGLTCASGVSLDDEELDKK
AIYQNDIVYTTNSELGFDYLTDNLVDNINKKKLNDLNFALVDEVDSVLLDLAQTPLVISGAPRVQSNLFVSTDRIVKSLK
PNVDFEFSEDLKDVWFTQTGIEQLEEYLGIQGLISDKWSDFYRHLVLALKANYVMKRNQDYIVTNREVLLLDSENGRALT
GMKLEAGIHQAIEAKEEVELSDQTRSMASITLQNFFKMFRKLSGMTGTAKSSAREFLEVYNLPVLKIPTHKPNIRIDHAD
VVFATMDEKIEATVRMVKAAYQIKRPVLLKTGSLSLSRLYSRVLLEHGIVHNVLNAQSESKEAMIVASAGKSGAITVATS
MAGRGTDIKLGKGVKEKGGLLVIGTERMDSRRVDDQLRGRAGRQGDPGESIFLVSLDDKVVIENAPDWVEKYRLKLEQAV
EQGKRKYGAPLKGRRARKIVEKAQQAADSAAEESRKNAVKMDDILRIQRELIYDFRDYIMKSTDLTTMVQQIKNDYFNAI
ARENKKDAGKLLDFIINNVDYNYMDNDFNPEILESTADIKQYLEEIARNRWSQQQMIVNNKFKQNYLERLAVLKALDVAW
IEQVDNLQQLKTVVTSRSSGQHNPVFEYEKEAMHSFEQMKKLFWKNTVKYMLLSELIPGKNGSVRVEFP
>Mature_789_residues
MEFNLDNFRLRKYSKITKKILALGKKYQTLTDDQLRIKTETLRNKLVKGASLDSILIEAYATIREADFRVLGLKPFENQV
LGAVVLHYGNVAQMNTGEGKTLTATMPLYLNGLTGPGNFLVTVNSYLANRDAEEIGKVYKWMGLTCASGVSLDDEELDKK
AIYQNDIVYTTNSELGFDYLTDNLVDNINKKKLNDLNFALVDEVDSVLLDLAQTPLVISGAPRVQSNLFVSTDRIVKSLK
PNVDFEFSEDLKDVWFTQTGIEQLEEYLGIQGLISDKWSDFYRHLVLALKANYVMKRNQDYIVTNREVLLLDSENGRALT
GMKLEAGIHQAIEAKEEVELSDQTRSMASITLQNFFKMFRKLSGMTGTAKSSAREFLEVYNLPVLKIPTHKPNIRIDHAD
VVFATMDEKIEATVRMVKAAYQIKRPVLLKTGSLSLSRLYSRVLLEHGIVHNVLNAQSESKEAMIVASAGKSGAITVATS
MAGRGTDIKLGKGVKEKGGLLVIGTERMDSRRVDDQLRGRAGRQGDPGESIFLVSLDDKVVIENAPDWVEKYRLKLEQAV
EQGKRKYGAPLKGRRARKIVEKAQQAADSAAEESRKNAVKMDDILRIQRELIYDFRDYIMKSTDLTTMVQQIKNDYFNAI
ARENKKDAGKLLDFIINNVDYNYMDNDFNPEILESTADIKQYLEEIARNRWSQQQMIVNNKFKQNYLERLAVLKALDVAW
IEQVDNLQQLKTVVTSRSSGQHNPVFEYEKEAMHSFEQMKKLFWKNTVKYMLLSELIPGKNGSVRVEFP

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=841, Percent_Identity=35.077288941736, Blast_Score=464, Evalue=1e-132,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA2_PEDPA (Q03HZ9)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_803615.1
- ProteinModelPortal:   Q03HZ9
- SMR:   Q03HZ9
- STRING:   Q03HZ9
- GeneID:   4418763
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_0062
- NMPDR:   fig|278197.10.peg.57
- eggNOG:   COG0653
- HOGENOM:   HBG284200
- OMA:   SPRVQSN
- ProtClustDB:   PRK09200
- BioCyc:   PPEN278197:PEPE_0062-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR000185
- InterPro:   IPR022490
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958
- TIGRFAMs:   TIGR03714

Pfam domain/function: PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 89473; Mature: 89473

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFNLDNFRLRKYSKITKKILALGKKYQTLTDDQLRIKTETLRNKLVKGASLDSILIEAY
CCCCCCCHHHHHHHHHHHHHHHHCCHHCCCCCCHHEEHHHHHHHHHHCCCCHHHHHHHHH
ATIREADFRVLGLKPFENQVLGAVVLHYGNVAQMNTGEGKTLTATMPLYLNGLTGPGNFL
HHHHHCCEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCCEEEEEECEEEECCCCCCCEE
VTVNSYLANRDAEEIGKVYKWMGLTCASGVSLDDEELDKKAIYQNDIVYTTNSELGFDYL
EEEEHHHCCCCHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHCCCEEEECCCCCCHHHH
TDNLVDNINKKKLNDLNFALVDEVDSVLLDLAQTPLVISGAPRVQSNLFVSTDRIVKSLK
HHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEHHHHHHHHC
PNVDFEFSEDLKDVWFTQTGIEQLEEYLGIQGLISDKWSDFYRHLVLALKANYVMKRNQD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YIVTNREVLLLDSENGRALTGMKLEAGIHQAIEAKEEVELSDQTRSMASITLQNFFKMFR
EEEECCEEEEEECCCCCEEECEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
KLSGMTGTAKSSAREFLEVYNLPVLKIPTHKPNIRIDHADVVFATMDEKIEATVRMVKAA
HHCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCEEEEEHHHHHHHHHHHHHHH
YQIKRPVLLKTGSLSLSRLYSRVLLEHGIVHNVLNAQSESKEAMIVASAGKSGAITVATS
HHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEEE
MAGRGTDIKLGKGVKEKGGLLVIGTERMDSRRVDDQLRGRAGRQGDPGESIFLVSLDDKV
CCCCCCCEECCCCCCCCCCEEEEECCCCCCHHCCHHHHCCCCCCCCCCCEEEEEEECCEE
VIENAPDWVEKYRLKLEQAVEQGKRKYGAPLKGRRARKIVEKAQQAADSAAEESRKNAVK
EECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
MDDILRIQRELIYDFRDYIMKSTDLTTMVQQIKNDYFNAIARENKKDAGKLLDFIINNVD
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
YNYMDNDFNPEILESTADIKQYLEEIARNRWSQQQMIVNNKFKQNYLERLAVLKALDVAW
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEQVDNLQQLKTVVTSRSSGQHNPVFEYEKEAMHSFEQMKKLFWKNTVKYMLLSELIPGK
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NGSVRVEFP
CCCEEEECC
>Mature Secondary Structure
MEFNLDNFRLRKYSKITKKILALGKKYQTLTDDQLRIKTETLRNKLVKGASLDSILIEAY
CCCCCCCHHHHHHHHHHHHHHHHCCHHCCCCCCHHEEHHHHHHHHHHCCCCHHHHHHHHH
ATIREADFRVLGLKPFENQVLGAVVLHYGNVAQMNTGEGKTLTATMPLYLNGLTGPGNFL
HHHHHCCEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCCEEEEEECEEEECCCCCCCEE
VTVNSYLANRDAEEIGKVYKWMGLTCASGVSLDDEELDKKAIYQNDIVYTTNSELGFDYL
EEEEHHHCCCCHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHCCCEEEECCCCCCHHHH
TDNLVDNINKKKLNDLNFALVDEVDSVLLDLAQTPLVISGAPRVQSNLFVSTDRIVKSLK
HHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEHHHHHHHHC
PNVDFEFSEDLKDVWFTQTGIEQLEEYLGIQGLISDKWSDFYRHLVLALKANYVMKRNQD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YIVTNREVLLLDSENGRALTGMKLEAGIHQAIEAKEEVELSDQTRSMASITLQNFFKMFR
EEEECCEEEEEECCCCCEEECEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
KLSGMTGTAKSSAREFLEVYNLPVLKIPTHKPNIRIDHADVVFATMDEKIEATVRMVKAA
HHCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCEEEEEHHHHHHHHHHHHHHH
YQIKRPVLLKTGSLSLSRLYSRVLLEHGIVHNVLNAQSESKEAMIVASAGKSGAITVATS
HHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEEE
MAGRGTDIKLGKGVKEKGGLLVIGTERMDSRRVDDQLRGRAGRQGDPGESIFLVSLDDKV
CCCCCCCEECCCCCCCCCCEEEEECCCCCCHHCCHHHHCCCCCCCCCCCEEEEEEECCEE
VIENAPDWVEKYRLKLEQAVEQGKRKYGAPLKGRRARKIVEKAQQAADSAAEESRKNAVK
EECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
MDDILRIQRELIYDFRDYIMKSTDLTTMVQQIKNDYFNAIARENKKDAGKLLDFIINNVD
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
YNYMDNDFNPEILESTADIKQYLEEIARNRWSQQQMIVNNKFKQNYLERLAVLKALDVAW
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEQVDNLQQLKTVVTSRSSGQHNPVFEYEKEAMHSFEQMKKLFWKNTVKYMLLSELIPGK
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NGSVRVEFP
CCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA