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The map label for this gene is yajO [H]

Identifier: 116491879

GI number: 116491879

Start: 62378

End: 63400

Strand: Direct

Name: yajO [H]

Synonym: PEPE_0061

Alternate gene names: 116491879

Gene position: 62378-63400 (Clockwise)

Preceding gene: 116491877

Following gene: 116491880

Centisome position: 3.4

GC content: 39.59

Gene sequence:

>1023_bases
ATGACAAACGAATCAATGCAATATGCTAAATTAGGAAAAACTGATATCGAAGTTTCAAAAATTTGTATTGGGGCAATGAG
TTTTGGACAACCAGGGACGATGCATGATTGGACACTAGATTACCCGGAAAGTGAAAAGGTGATTCGACATGCTTTAAATC
TTGGAATTAACTTCTTTGATACGGCCAATGTTTATTCCAAAGGAACCAGTGAAGAATTTTTAGGGCGCGCATTAAAAGAA
AATAATATTGCACGTGACCAAGTTGTGATTGCTTCGAAGGTTTATTTCAATGAAGGACGGCTTTCAAAAGATGCAATTAA
CCGTGAAATTGATGGCACGCTCCGTCGTTTAGGTACAGATTACCTTGATTTATATATTATTCATCGCTTTGATTACCAAA
CGCCGATTGAAGAAACTATGTCAGCCTTAAATGATTTAGTAGTGGCTGGTAAAGTTCGTGCAATTGGGGCTTCAGCAATG
TATGGATATCAATTCTACAACATGCAACAAGTGGCTAAGGATCATGGTTGGGCTCAGTTCCAAACTATGGAAAATCACTA
TAATTTACTATATCGTGAAGATGAACGCGAATTAATTCCTATTTGTCAGCAAATGGATGTTTCTCTAATGCCTTACAGTC
CACTAGCGGCTGGGCATTTGAGTCGTCGAACCTGGCAAACGGATACTTTGCGCAGCAAGACTGATCGGGTGGCCATGGGA
AAATATGATCGAACAGAGGCTGAGGATATCAAGATTGTTAAACGAGTTGGTGAATTAGCCGATCGCTATGACGTTACCAT
GTCGCAAATTGCGTTAGCTTGGCAATGGGCCAAAGGGGTAACAGCTCCTATTATTGGTTCAACGAAGGCCAAACATTTAG
ATGATGCAGTAGCTGCTTTATCGGTTAAATTAACAAATGATGATGTTAAATACTTAGAAGAAATGTATATTCCCCATCCA
ATTGTAGGTGCGGTTGCGGAAAATCCAGCAGCAGGAACTGTATTAGTAGATGAGAAGAAATAA

Upstream 100 bases:

>100_bases
TGGTTATAAAAGTGATATTAATAGCTATCAGTCTACACTAAACGTGTGATTGATGAAAATGGTGGTTGTAAAATATTCTA
GATTGGAGTGGGTGGATTTT

Downstream 100 bases:

>100_bases
GTTAATTTGAATTAATCAAAAATAAAAACGGCTGTCAGAAGTAATTTCTGAGGGTCGTTTTTTCAGATTTAAACAGTTTT
AATTTAAAATATATTTAATT

Product: Aryl-alcohol dehydrogenase related enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTNESMQYAKLGKTDIEVSKICIGAMSFGQPGTMHDWTLDYPESEKVIRHALNLGINFFDTANVYSKGTSEEFLGRALKE
NNIARDQVVIASKVYFNEGRLSKDAINREIDGTLRRLGTDYLDLYIIHRFDYQTPIEETMSALNDLVVAGKVRAIGASAM
YGYQFYNMQQVAKDHGWAQFQTMENHYNLLYREDERELIPICQQMDVSLMPYSPLAAGHLSRRTWQTDTLRSKTDRVAMG
KYDRTEAEDIKIVKRVGELADRYDVTMSQIALAWQWAKGVTAPIIGSTKAKHLDDAVAALSVKLTNDDVKYLEEMYIPHP
IVGAVAENPAAGTVLVDEKK

Sequences:

>Translated_340_residues
MTNESMQYAKLGKTDIEVSKICIGAMSFGQPGTMHDWTLDYPESEKVIRHALNLGINFFDTANVYSKGTSEEFLGRALKE
NNIARDQVVIASKVYFNEGRLSKDAINREIDGTLRRLGTDYLDLYIIHRFDYQTPIEETMSALNDLVVAGKVRAIGASAM
YGYQFYNMQQVAKDHGWAQFQTMENHYNLLYREDERELIPICQQMDVSLMPYSPLAAGHLSRRTWQTDTLRSKTDRVAMG
KYDRTEAEDIKIVKRVGELADRYDVTMSQIALAWQWAKGVTAPIIGSTKAKHLDDAVAALSVKLTNDDVKYLEEMYIPHP
IVGAVAENPAAGTVLVDEKK
>Mature_339_residues
TNESMQYAKLGKTDIEVSKICIGAMSFGQPGTMHDWTLDYPESEKVIRHALNLGINFFDTANVYSKGTSEEFLGRALKEN
NIARDQVVIASKVYFNEGRLSKDAINREIDGTLRRLGTDYLDLYIIHRFDYQTPIEETMSALNDLVVAGKVRAIGASAMY
GYQFYNMQQVAKDHGWAQFQTMENHYNLLYREDERELIPICQQMDVSLMPYSPLAAGHLSRRTWQTDTLRSKTDRVAMGK
YDRTEAEDIKIVKRVGELADRYDVTMSQIALAWQWAKGVTAPIIGSTKAKHLDDAVAALSVKLTNDDVKYLEEMYIPHPI
VGAVAENPAAGTVLVDEKK

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=333, Percent_Identity=27.3273273273273, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI27436962, Length=333, Percent_Identity=27.3273273273273, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI27436969, Length=313, Percent_Identity=27.7955271565495, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI27436966, Length=333, Percent_Identity=27.027027027027, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI4504825, Length=311, Percent_Identity=27.6527331189711, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI27436971, Length=313, Percent_Identity=27.4760383386581, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI223718702, Length=266, Percent_Identity=27.4436090225564, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI41152114, Length=200, Percent_Identity=30, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI41327764, Length=171, Percent_Identity=30.9941520467836, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI223718708, Length=156, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI87081735, Length=324, Percent_Identity=47.8395061728395, Blast_Score=312, Evalue=2e-86,
Organism=Escherichia coli, GI1788070, Length=332, Percent_Identity=30.421686746988, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1788081, Length=275, Percent_Identity=32.7272727272727, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1789375, Length=323, Percent_Identity=29.7213622291022, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789199, Length=347, Percent_Identity=25.6484149855908, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786400, Length=264, Percent_Identity=25.7575757575758, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI48994888, Length=284, Percent_Identity=26.4084507042254, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI87082198, Length=246, Percent_Identity=23.5772357723577, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI212645785, Length=180, Percent_Identity=32.7777777777778, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=336, Percent_Identity=38.6904761904762, Blast_Score=226, Evalue=3e-60,
Organism=Saccharomyces cerevisiae, GI6323998, Length=342, Percent_Identity=28.6549707602339, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6319958, Length=295, Percent_Identity=29.4915254237288, Blast_Score=123, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6319951, Length=324, Percent_Identity=27.1604938271605, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6322615, Length=270, Percent_Identity=28.1481481481481, Blast_Score=109, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6320079, Length=278, Percent_Identity=26.2589928057554, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321052, Length=145, Percent_Identity=28.9655172413793, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24646155, Length=164, Percent_Identity=36.5853658536585, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24640980, Length=362, Percent_Identity=21.8232044198895, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45549126, Length=362, Percent_Identity=21.8232044198895, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24646159, Length=329, Percent_Identity=27.0516717325228, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 38394; Mature: 38263

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNESMQYAKLGKTDIEVSKICIGAMSFGQPGTMHDWTLDYPESEKVIRHALNLGINFFD
CCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEE
TANVYSKGTSEEFLGRALKENNIARDQVVIASKVYFNEGRLSKDAINREIDGTLRRLGTD
CCCHHCCCCHHHHHHHHHHHCCCCHHHEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCH
YLDLYIIHRFDYQTPIEETMSALNDLVVAGKVRAIGASAMYGYQFYNMQQVAKDHGWAQF
HEEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHECCHHHHHHHHHHHHHHHHHHCCCHHE
QTMENHYNLLYREDERELIPICQQMDVSLMPYSPLAAGHLSRRTWQTDTLRSKTDRVAMG
EEHHCCCCEEEECCCCHHHHHHHHCCCEECCCCCHHHHHHHCCCCCCHHHHHHCCCEECC
KYDRTEAEDIKIVKRVGELADRYDVTMSQIALAWQWAKGVTAPIIGSTKAKHLDDAVAAL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHEE
SVKLTNDDVKYLEEMYIPHPIVGAVAENPAAGTVLVDEKK
EEEECCCHHHHHHHHCCCCCHHHHHCCCCCCCEEEEECCC
>Mature Secondary Structure 
TNESMQYAKLGKTDIEVSKICIGAMSFGQPGTMHDWTLDYPESEKVIRHALNLGINFFD
CCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEE
TANVYSKGTSEEFLGRALKENNIARDQVVIASKVYFNEGRLSKDAINREIDGTLRRLGTD
CCCHHCCCCHHHHHHHHHHHCCCCHHHEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCH
YLDLYIIHRFDYQTPIEETMSALNDLVVAGKVRAIGASAMYGYQFYNMQQVAKDHGWAQF
HEEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHECCHHHHHHHHHHHHHHHHHHCCCHHE
QTMENHYNLLYREDERELIPICQQMDVSLMPYSPLAAGHLSRRTWQTDTLRSKTDRVAMG
EEHHCCCCEEEECCCCHHHHHHHHCCCEECCCCCHHHHHHHCCCCCCHHHHHHCCCEECC
KYDRTEAEDIKIVKRVGELADRYDVTMSQIALAWQWAKGVTAPIIGSTKAKHLDDAVAAL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHEE
SVKLTNDDVKYLEEMYIPHPIVGAVAENPAAGTVLVDEKK
EEEECCCHHHHHHHHCCCCCHHHHHCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]