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The map label for this gene is adhR [H]

Identifier: 116491878

GI number: 116491878

Start: 61866

End: 62231

Strand: Reverse

Name: adhR [H]

Synonym: PEPE_0060

Alternate gene names: 116491878

Gene position: 62231-61866 (Counterclockwise)

Preceding gene: 116491892

Following gene: 116491876

Centisome position: 3.4

GC content: 38.25

Gene sequence:

>366_bases
ATGAAAATCGAAGAAGTTGCCACACAATTTTCTATCTCAAGTCCCACCCTCCGTTACTATGAACACGAAGGATTATTAGG
TCCTGTTAAACGTGTCCACGGCATCCGTGACTATTCCGATCGTGACCTTGAGCGTCTAGATTTTATTCTATGCACAAAAA
AATGTGGAATGTCTTTAAAACAAATACAGCATTTCATTAATATTTACGAACAAGGCGATGAAACCATACCTGAGCGATTA
GCTATTCTCCAAGAACAGCTGGCTAAAACTCAAACCACCTTGATCGAACTAACCCAATCTATGGATCATTTGAAAGATAA
AATAGATGATCTTCATCAATTAGCGACTACCCATTCTGGAAAATAG

Upstream 100 bases:

>100_bases
ATCAATCACACGTTTAGTGTAGACTGATAGCTATTAATATCACTTTTATAACCATAGTTTACTCCTTAAAGTAAGCTTTA
AGTCAAGCGAGGATTTTACA

Downstream 100 bases:

>100_bases
ATTCTTAAATTCATTAGCCGCTTAACACAAAAACACTCAACATCAGTTTTTAACTAATGTTGAGTGTTTTATTTTAGATT
AAATGTTATTTAATCTTCGT

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 121; Mature: 121

Protein sequence:

>121_residues
MKIEEVATQFSISSPTLRYYEHEGLLGPVKRVHGIRDYSDRDLERLDFILCTKKCGMSLKQIQHFINIYEQGDETIPERL
AILQEQLAKTQTTLIELTQSMDHLKDKIDDLHQLATTHSGK

Sequences:

>Translated_121_residues
MKIEEVATQFSISSPTLRYYEHEGLLGPVKRVHGIRDYSDRDLERLDFILCTKKCGMSLKQIQHFINIYEQGDETIPERL
AILQEQLAKTQTTLIELTQSMDHLKDKIDDLHQLATTHSGK
>Mature_121_residues
MKIEEVATQFSISSPTLRYYEHEGLLGPVKRVHGIRDYSDRDLERLDFILCTKKCGMSLKQIQHFINIYEQGDETIPERL
AILQEQLAKTQTTLIELTQSMDHLKDKIDDLHQLATTHSGK

Specific function: Transcriptional regulator involved in the response to aldehyde stress. Binds to the promoter region of the adhA-yraA operon, the yraC and its own promoter region; binding is unchanged in the presence of aldehydes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 13998; Mature: 13998

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIEEVATQFSISSPTLRYYEHEGLLGPVKRVHGIRDYSDRDLERLDFILCTKKCGMSLK
CCHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHH
QIQHFINIYEQGDETIPERLAILQEQLAKTQTTLIELTQSMDHLKDKIDDLHQLATTHSG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
K
C
>Mature Secondary Structure
MKIEEVATQFSISSPTLRYYEHEGLLGPVKRVHGIRDYSDRDLERLDFILCTKKCGMSLK
CCHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHH
QIQHFINIYEQGDETIPERLAILQEQLAKTQTTLIELTQSMDHLKDKIDDLHQLATTHSG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141695; 9384377 [H]